Gene expression of the endolymphatic sac

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Gene expression of the endolymphatic sac. / Friis, Morten; Martin-Bertelsen, Tomas; Friis-Hansen, Lennart; Winther, Ole; Henao Giraldo, Ricardo; Sørensen, Mads Sølvsten; Qvortrup, Klaus.

In: Acta Oto-Laryngologica, Vol. 131, No. 12, 2011, p. 1257-63.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Friis, M, Martin-Bertelsen, T, Friis-Hansen, L, Winther, O, Henao Giraldo, R, Sørensen, MS & Qvortrup, K 2011, 'Gene expression of the endolymphatic sac', Acta Oto-Laryngologica, vol. 131, no. 12, pp. 1257-63. https://doi.org/10.3109/00016489.2011.616910

APA

Friis, M., Martin-Bertelsen, T., Friis-Hansen, L., Winther, O., Henao Giraldo, R., Sørensen, M. S., & Qvortrup, K. (2011). Gene expression of the endolymphatic sac. Acta Oto-Laryngologica, 131(12), 1257-63. https://doi.org/10.3109/00016489.2011.616910

Vancouver

Friis M, Martin-Bertelsen T, Friis-Hansen L, Winther O, Henao Giraldo R, Sørensen MS et al. Gene expression of the endolymphatic sac. Acta Oto-Laryngologica. 2011;131(12):1257-63. https://doi.org/10.3109/00016489.2011.616910

Author

Friis, Morten ; Martin-Bertelsen, Tomas ; Friis-Hansen, Lennart ; Winther, Ole ; Henao Giraldo, Ricardo ; Sørensen, Mads Sølvsten ; Qvortrup, Klaus. / Gene expression of the endolymphatic sac. In: Acta Oto-Laryngologica. 2011 ; Vol. 131, No. 12. pp. 1257-63.

Bibtex

@article{471115513dd74a8aabe2f1216a8ae82a,
title = "Gene expression of the endolymphatic sac",
abstract = "Conclusion: The endolymphatic sac is part of the membranous inner ear and is thought to play a role in the fluid homeostasis and immune defense of the inner ear; however, the exact function of the endolymphatic sac is not fully known. Many of the detected mRNAs in this study suggest that the endolymphatic sac has multiple and diverse functions in the inner ear. Objectives:The objective of this study was to provide a comprehensive review of the genes expressed in the endolymphatic sac in the rat and perform a functional characterization based on measured mRNA abundance. Methods:Microarray technology was used to investigate the gene expression of the endolymphatic sac with the surrounding dura. Characteristic and novel endolymphatic sac genes were determined by comparing with expressions in pure dura. Results: In all, 463 genes were identified specific for the endolymphatic sac. Functional annotation clustering revealed 29 functional clusters.",
author = "Morten Friis and Tomas Martin-Bertelsen and Lennart Friis-Hansen and Ole Winther and {Henao Giraldo}, Ricardo and S{\o}rensen, {Mads S{\o}lvsten} and Klaus Qvortrup",
year = "2011",
doi = "10.3109/00016489.2011.616910",
language = "English",
volume = "131",
pages = "1257--63",
journal = "Acta Oto-Laryngologica",
issn = "0001-6489",
publisher = "Taylor & Francis",
number = "12",

}

RIS

TY - JOUR

T1 - Gene expression of the endolymphatic sac

AU - Friis, Morten

AU - Martin-Bertelsen, Tomas

AU - Friis-Hansen, Lennart

AU - Winther, Ole

AU - Henao Giraldo, Ricardo

AU - Sørensen, Mads Sølvsten

AU - Qvortrup, Klaus

PY - 2011

Y1 - 2011

N2 - Conclusion: The endolymphatic sac is part of the membranous inner ear and is thought to play a role in the fluid homeostasis and immune defense of the inner ear; however, the exact function of the endolymphatic sac is not fully known. Many of the detected mRNAs in this study suggest that the endolymphatic sac has multiple and diverse functions in the inner ear. Objectives:The objective of this study was to provide a comprehensive review of the genes expressed in the endolymphatic sac in the rat and perform a functional characterization based on measured mRNA abundance. Methods:Microarray technology was used to investigate the gene expression of the endolymphatic sac with the surrounding dura. Characteristic and novel endolymphatic sac genes were determined by comparing with expressions in pure dura. Results: In all, 463 genes were identified specific for the endolymphatic sac. Functional annotation clustering revealed 29 functional clusters.

AB - Conclusion: The endolymphatic sac is part of the membranous inner ear and is thought to play a role in the fluid homeostasis and immune defense of the inner ear; however, the exact function of the endolymphatic sac is not fully known. Many of the detected mRNAs in this study suggest that the endolymphatic sac has multiple and diverse functions in the inner ear. Objectives:The objective of this study was to provide a comprehensive review of the genes expressed in the endolymphatic sac in the rat and perform a functional characterization based on measured mRNA abundance. Methods:Microarray technology was used to investigate the gene expression of the endolymphatic sac with the surrounding dura. Characteristic and novel endolymphatic sac genes were determined by comparing with expressions in pure dura. Results: In all, 463 genes were identified specific for the endolymphatic sac. Functional annotation clustering revealed 29 functional clusters.

U2 - 10.3109/00016489.2011.616910

DO - 10.3109/00016489.2011.616910

M3 - Journal article

C2 - 22017353

VL - 131

SP - 1257

EP - 1263

JO - Acta Oto-Laryngologica

JF - Acta Oto-Laryngologica

SN - 0001-6489

IS - 12

ER -

ID: 35165492