Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion
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Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion. / Riber, C; Hojgaard, L; Madsen, J L; Rehfeld, J F; Olsen, O.
In: Digestion, Vol. 57, No. 3, 1996, p. 161-4.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion
AU - Riber, C
AU - Hojgaard, L
AU - Madsen, J L
AU - Rehfeld, J F
AU - Olsen, O
PY - 1996
Y1 - 1996
N2 - The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration of fish oil and trioleate. After intravenous injection of 99mTc-HIDA, 30 ml of a lipid labelled with 111In was administered through a gastric tube. Using dual scintigraphy with two markers, gallbladder and gastric emptying were measured simultaneously for 120 min. Plasma concentrations of gastrin, secretin and CCK, were determined throughout the period. The emptying of the gallbladder was reduced by 27% and the release of CCK by 85% after fish oil as compared with trioleate. Gastric emptying as well as the release of gastrin and secretin were similar after the two types of fat. The results suggest that the reduced gallbladder emptying after fish oil may be due to a smaller release of CCK.
AB - The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration of fish oil and trioleate. After intravenous injection of 99mTc-HIDA, 30 ml of a lipid labelled with 111In was administered through a gastric tube. Using dual scintigraphy with two markers, gallbladder and gastric emptying were measured simultaneously for 120 min. Plasma concentrations of gastrin, secretin and CCK, were determined throughout the period. The emptying of the gallbladder was reduced by 27% and the release of CCK by 85% after fish oil as compared with trioleate. Gastric emptying as well as the release of gastrin and secretin were similar after the two types of fat. The results suggest that the reduced gallbladder emptying after fish oil may be due to a smaller release of CCK.
KW - Adult
KW - Cholecystokinin
KW - Fatty Acids, Omega-3
KW - Fish Oils
KW - Gallbladder Emptying
KW - Gastric Emptying
KW - Gastrins
KW - Humans
KW - Imino Acids
KW - Indium Radioisotopes
KW - Male
KW - Organotechnetium Compounds
KW - Radioimmunoassay
KW - Secretin
KW - Technetium Tc 99m Lidofenin
KW - Triolein
KW - Comparative Study
KW - Journal Article
M3 - Journal article
C2 - 8739088
VL - 57
SP - 161
EP - 164
JO - Digestion
JF - Digestion
SN - 0012-2823
IS - 3
ER -
ID: 165885729