Experimental and biological variation of three-dimensional transcranial Doppler measurements

Research output: Contribution to journal › Journal article › peer-review

Standard

Experimental and biological variation of three-dimensional transcranial Doppler measurements. / Thomsen, L L; Iversen, Helle Klingenberg.

In: Journal of Applied Physiology, Vol. 75, No. 6, 12.1993, p. 2805-10.

Research output: Contribution to journal › Journal article › peer-review

Harvard

Thomsen, LL & Iversen, HK 1993, 'Experimental and biological variation of three-dimensional transcranial Doppler measurements', Journal of Applied Physiology, vol. 75, no. 6, pp. 2805-10.

APA

Thomsen, L. L., & Iversen, H. K. (1993). Experimental and biological variation of three-dimensional transcranial Doppler measurements. Journal of Applied Physiology, 75(6), 2805-10.

Vancouver

Thomsen LL, Iversen HK. Experimental and biological variation of three-dimensional transcranial Doppler measurements. Journal of Applied Physiology. 1993 Dec;75(6):2805-10.

Author

Thomsen, L L ; Iversen, Helle Klingenberg. / Experimental and biological variation of three-dimensional transcranial Doppler measurements. In: Journal of Applied Physiology. 1993 ; Vol. 75, No. 6. pp. 2805-10.

Bibtex

@article{505daebee20c4b94937906de8118e40f,
title = "Experimental and biological variation of three-dimensional transcranial Doppler measurements",
abstract = "A new transcranial Doppler system (3-D Transscan, Eden Medizinische Elektronik) was evaluated in relation to sex, age, intersubject, interobserver, side-to-side, and day-to-day variation. Fifty-eight healthy volunteers participated (aged 18-80 yr). Mean velocity was higher in females than in males and decreased with age. The coefficient of variation in the middle cerebral artery was 26% between subjects, 20% between sides, 16% between days, 13% between observers, and 7% during 5 min. The coefficient of variation was higher in the anterior and posterior cerebral arteries. Bruits were heard in 35 subjects, 24 females and 11 males (P = 0.002). When middle cerebral artery velocity was monitored, high- and low-frequency oscillations were found, with a mean frequency of 5 and 1.6/min, respectively. These variations underline the necessity of standardized conditions and very carefully matched control groups in studies using transcranial Doppler. This is especially important when expected changes are small and easy to overlook, as in studies of normal physiological responses and migraine.",
keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Aging, Blood Pressure, Carbon Dioxide, Cerebral Arteries, Cerebrovascular Circulation, Female, Headache, Heart Rate, Humans, Male, Middle Aged, Myocardial Infarction, Reference Values, Sex Characteristics, Ultrasonography, Doppler, Transcranial",
author = "Thomsen, {L L} and Iversen, {Helle Klingenberg}",
year = "1993",
month = dec,
language = "English",
volume = "75",
pages = "2805--10",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "6",

}

RIS

TY - JOUR

T1 - Experimental and biological variation of three-dimensional transcranial Doppler measurements

AU - Thomsen, L L

AU - Iversen, Helle Klingenberg

PY - 1993/12

Y1 - 1993/12

N2 - A new transcranial Doppler system (3-D Transscan, Eden Medizinische Elektronik) was evaluated in relation to sex, age, intersubject, interobserver, side-to-side, and day-to-day variation. Fifty-eight healthy volunteers participated (aged 18-80 yr). Mean velocity was higher in females than in males and decreased with age. The coefficient of variation in the middle cerebral artery was 26% between subjects, 20% between sides, 16% between days, 13% between observers, and 7% during 5 min. The coefficient of variation was higher in the anterior and posterior cerebral arteries. Bruits were heard in 35 subjects, 24 females and 11 males (P = 0.002). When middle cerebral artery velocity was monitored, high- and low-frequency oscillations were found, with a mean frequency of 5 and 1.6/min, respectively. These variations underline the necessity of standardized conditions and very carefully matched control groups in studies using transcranial Doppler. This is especially important when expected changes are small and easy to overlook, as in studies of normal physiological responses and migraine.

AB - A new transcranial Doppler system (3-D Transscan, Eden Medizinische Elektronik) was evaluated in relation to sex, age, intersubject, interobserver, side-to-side, and day-to-day variation. Fifty-eight healthy volunteers participated (aged 18-80 yr). Mean velocity was higher in females than in males and decreased with age. The coefficient of variation in the middle cerebral artery was 26% between subjects, 20% between sides, 16% between days, 13% between observers, and 7% during 5 min. The coefficient of variation was higher in the anterior and posterior cerebral arteries. Bruits were heard in 35 subjects, 24 females and 11 males (P = 0.002). When middle cerebral artery velocity was monitored, high- and low-frequency oscillations were found, with a mean frequency of 5 and 1.6/min, respectively. These variations underline the necessity of standardized conditions and very carefully matched control groups in studies using transcranial Doppler. This is especially important when expected changes are small and easy to overlook, as in studies of normal physiological responses and migraine.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Aging

KW - Blood Pressure

KW - Carbon Dioxide

KW - Cerebral Arteries

KW - Cerebrovascular Circulation

KW - Female

KW - Headache

KW - Heart Rate

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Reference Values

KW - Sex Characteristics

KW - Ultrasonography, Doppler, Transcranial

M3 - Journal article

C2 - 7907324

VL - 75

SP - 2805

EP - 2810

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 6

ER -

ID: 128984472