Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet

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Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet. / Gelabert, Pere; Sandoval-Velasco, Marcela; Serres, Aitor; de Manuel, Marc; Renom, Pere; Margaryan, Ashot; Stiller, Josefin; de-Dios, Toni; Fang, Qi; Feng, Shaohong; Mañosa, Santi; Pacheco, George; Ferrando-Bernal, Manuel; Shi, Guolin; Hao, Fei; Chen, Xianqing; Petersen, Bent; Olsen, Remi-André; Navarro, Arcadi; Deng, Yuan; Dalén, Love; Marquès-Bonet, Tomàs; Zhang, Guojie; Antunes, Agostinho; Gilbert, M. Thomas P.; Lalueza-Fox, Carles.

In: Current Biology, Vol. 30, No. 1, 2020, p. 108-114, e1-e5.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Gelabert, P, Sandoval-Velasco, M, Serres, A, de Manuel, M, Renom, P, Margaryan, A, Stiller, J, de-Dios, T, Fang, Q, Feng, S, Mañosa, S, Pacheco, G, Ferrando-Bernal, M, Shi, G, Hao, F, Chen, X, Petersen, B, Olsen, R-A, Navarro, A, Deng, Y, Dalén, L, Marquès-Bonet, T, Zhang, G, Antunes, A, Gilbert, MTP & Lalueza-Fox, C 2020, 'Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet', Current Biology, vol. 30, no. 1, pp. 108-114, e1-e5. https://doi.org/10.1016/j.cub.2019.10.066

APA

Gelabert, P., Sandoval-Velasco, M., Serres, A., de Manuel, M., Renom, P., Margaryan, A., ... Lalueza-Fox, C. (2020). Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet. Current Biology, 30(1), 108-114, e1-e5. https://doi.org/10.1016/j.cub.2019.10.066

Vancouver

Gelabert P, Sandoval-Velasco M, Serres A, de Manuel M, Renom P, Margaryan A et al. Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet. Current Biology. 2020;30(1):108-114, e1-e5. https://doi.org/10.1016/j.cub.2019.10.066

Author

Gelabert, Pere ; Sandoval-Velasco, Marcela ; Serres, Aitor ; de Manuel, Marc ; Renom, Pere ; Margaryan, Ashot ; Stiller, Josefin ; de-Dios, Toni ; Fang, Qi ; Feng, Shaohong ; Mañosa, Santi ; Pacheco, George ; Ferrando-Bernal, Manuel ; Shi, Guolin ; Hao, Fei ; Chen, Xianqing ; Petersen, Bent ; Olsen, Remi-André ; Navarro, Arcadi ; Deng, Yuan ; Dalén, Love ; Marquès-Bonet, Tomàs ; Zhang, Guojie ; Antunes, Agostinho ; Gilbert, M. Thomas P. ; Lalueza-Fox, Carles. / Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet. In: Current Biology. 2020 ; Vol. 30, No. 1. pp. 108-114, e1-e5.

Bibtex

@article{3229ab3a32944a4cac952e0e0c830295,
title = "Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet",
abstract = "As the only endemic neotropical parrot to have recently lived in the northern hemisphere, the Carolina parakeet (Conuropsis carolinensis) was an iconic North American bird. The last surviving specimen died in the Cincinnati Zoo in 1918 [1]. The cause of its extinction remains contentious: besides excessive mortality associated to habitat destruction and active hunting, their survival could have been negatively affected by its range having become increasingly patchy [2] or by the exposure to poultry pathogens [3, 4]. In addition, the Carolina parakeet showed a predilection for cockleburs, an herbaceous plant that contains a powerful toxin, carboxyatractyloside, or CAT [5], which did not seem to affect them but made the birds notoriously toxic to most predators [3]. To explore the demographic history of this bird, we generated the complete genomic sequence of a preserved specimen held in a private collection in Espinelves (Girona, Spain), as well as of a close extant relative, Aratinga solstitialis. We identified two non-synonymous genetic changes in two highly conserved proteins known to interact with CAT that could underlie a specific dietary adaptation to this toxin. Our genomic analyses did not reveal evidence of a dramatic past demographic decline in the Carolina parakeet; also, its genome did not exhibit the long runs of homozygosity that are signals of recent inbreeding and are typically found in endangered species. As such, our results suggest its extinction was an abrupt process and thus likely solely attributable to human causes.",
author = "Pere Gelabert and Marcela Sandoval-Velasco and Aitor Serres and {de Manuel}, Marc and Pere Renom and Ashot Margaryan and Josefin Stiller and Toni de-Dios and Qi Fang and Shaohong Feng and Santi Ma{\~n}osa and George Pacheco and Manuel Ferrando-Bernal and Guolin Shi and Fei Hao and Xianqing Chen and Bent Petersen and Remi-Andr{\'e} Olsen and Arcadi Navarro and Yuan Deng and Love Dal{\'e}n and Tom{\`a}s Marqu{\`e}s-Bonet and Guojie Zhang and Agostinho Antunes and Gilbert, {M. Thomas P.} and Carles Lalueza-Fox",
note = "Copyright {\circledC} 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.",
year = "2020",
doi = "10.1016/j.cub.2019.10.066",
language = "English",
volume = "30",
pages = "108--114, e1--e5",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "1",

}

RIS

TY - JOUR

T1 - Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet

AU - Gelabert, Pere

AU - Sandoval-Velasco, Marcela

AU - Serres, Aitor

AU - de Manuel, Marc

AU - Renom, Pere

AU - Margaryan, Ashot

AU - Stiller, Josefin

AU - de-Dios, Toni

AU - Fang, Qi

AU - Feng, Shaohong

AU - Mañosa, Santi

AU - Pacheco, George

AU - Ferrando-Bernal, Manuel

AU - Shi, Guolin

AU - Hao, Fei

AU - Chen, Xianqing

AU - Petersen, Bent

AU - Olsen, Remi-André

AU - Navarro, Arcadi

AU - Deng, Yuan

AU - Dalén, Love

AU - Marquès-Bonet, Tomàs

AU - Zhang, Guojie

AU - Antunes, Agostinho

AU - Gilbert, M. Thomas P.

AU - Lalueza-Fox, Carles

N1 - Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.

PY - 2020

Y1 - 2020

N2 - As the only endemic neotropical parrot to have recently lived in the northern hemisphere, the Carolina parakeet (Conuropsis carolinensis) was an iconic North American bird. The last surviving specimen died in the Cincinnati Zoo in 1918 [1]. The cause of its extinction remains contentious: besides excessive mortality associated to habitat destruction and active hunting, their survival could have been negatively affected by its range having become increasingly patchy [2] or by the exposure to poultry pathogens [3, 4]. In addition, the Carolina parakeet showed a predilection for cockleburs, an herbaceous plant that contains a powerful toxin, carboxyatractyloside, or CAT [5], which did not seem to affect them but made the birds notoriously toxic to most predators [3]. To explore the demographic history of this bird, we generated the complete genomic sequence of a preserved specimen held in a private collection in Espinelves (Girona, Spain), as well as of a close extant relative, Aratinga solstitialis. We identified two non-synonymous genetic changes in two highly conserved proteins known to interact with CAT that could underlie a specific dietary adaptation to this toxin. Our genomic analyses did not reveal evidence of a dramatic past demographic decline in the Carolina parakeet; also, its genome did not exhibit the long runs of homozygosity that are signals of recent inbreeding and are typically found in endangered species. As such, our results suggest its extinction was an abrupt process and thus likely solely attributable to human causes.

AB - As the only endemic neotropical parrot to have recently lived in the northern hemisphere, the Carolina parakeet (Conuropsis carolinensis) was an iconic North American bird. The last surviving specimen died in the Cincinnati Zoo in 1918 [1]. The cause of its extinction remains contentious: besides excessive mortality associated to habitat destruction and active hunting, their survival could have been negatively affected by its range having become increasingly patchy [2] or by the exposure to poultry pathogens [3, 4]. In addition, the Carolina parakeet showed a predilection for cockleburs, an herbaceous plant that contains a powerful toxin, carboxyatractyloside, or CAT [5], which did not seem to affect them but made the birds notoriously toxic to most predators [3]. To explore the demographic history of this bird, we generated the complete genomic sequence of a preserved specimen held in a private collection in Espinelves (Girona, Spain), as well as of a close extant relative, Aratinga solstitialis. We identified two non-synonymous genetic changes in two highly conserved proteins known to interact with CAT that could underlie a specific dietary adaptation to this toxin. Our genomic analyses did not reveal evidence of a dramatic past demographic decline in the Carolina parakeet; also, its genome did not exhibit the long runs of homozygosity that are signals of recent inbreeding and are typically found in endangered species. As such, our results suggest its extinction was an abrupt process and thus likely solely attributable to human causes.

U2 - 10.1016/j.cub.2019.10.066

DO - 10.1016/j.cub.2019.10.066

M3 - Journal article

C2 - 31839456

VL - 30

SP - 108-114, e1-e5

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 1

ER -

ID: 231955310