Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect

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Standard

Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. / Gorham, Katrine A; Andersen, Mads Peter Sulbæk; Meinardi, Simone; Delfino, Ralph J; Staimer, Norbert; Tjoa, Thomas; Rowland, F Sherwood; Blake, Donald R.

In: Biomarkers, Vol. 14, No. 1, 2009, p. 17-25.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gorham, KA, Andersen, MPS, Meinardi, S, Delfino, RJ, Staimer, N, Tjoa, T, Rowland, FS & Blake, DR 2009, 'Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect', Biomarkers, vol. 14, no. 1, pp. 17-25. https://doi.org/10.1080/13547500902730680

APA

Gorham, K. A., Andersen, M. P. S., Meinardi, S., Delfino, R. J., Staimer, N., Tjoa, T., Rowland, F. S., & Blake, D. R. (2009). Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. Biomarkers, 14(1), 17-25. https://doi.org/10.1080/13547500902730680

Vancouver

Gorham KA, Andersen MPS, Meinardi S, Delfino RJ, Staimer N, Tjoa T et al. Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. Biomarkers. 2009;14(1):17-25. https://doi.org/10.1080/13547500902730680

Author

Gorham, Katrine A ; Andersen, Mads Peter Sulbæk ; Meinardi, Simone ; Delfino, Ralph J ; Staimer, Norbert ; Tjoa, Thomas ; Rowland, F Sherwood ; Blake, Donald R. / Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. In: Biomarkers. 2009 ; Vol. 14, No. 1. pp. 17-25.

Bibtex

@article{c2e9cc98efab4732bfd23a318b3b983b,
title = "Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect",
abstract = "The relationship of exhaled ethane and n-pentane to exhaled NO, carbonylated proteins, and indoor/outdoor atmospheric pollutants were examined in order to evaluate ethane and n-pentane as potential markers of airway inflammation and/or oxidative stress. Exhaled NO and carbonylated proteins were found to have no significant associations with either ethane (p = 0.96 and p = 0.81, respectively) or n-pentane (p = 0.44 and 0.28, respectively) when outliers were included. In the case where outliers were removed n-pentane was found to be inversely associated with carbonylated proteins. Exhaled hydrocarbons adjusted for indoor hydrocarbon concentrations were instead found to be positively associated with air pollutants (NO, NO(2) and CO), suggesting pollutant exposure is driving exhaled hydrocarbon concentrations. Given these findings, ethane and n-pentane do not appear to be markers of airway inflammation or oxidative stress.",
keywords = "Aged, Aged, 80 and over, Biological Markers, Breath Tests, Ethane, Female, Humans, Male, Pentanes",
author = "Gorham, {Katrine A} and Andersen, {Mads Peter Sulb{\ae}k} and Simone Meinardi and Delfino, {Ralph J} and Norbert Staimer and Thomas Tjoa and Rowland, {F Sherwood} and Blake, {Donald R}",
year = "2009",
doi = "10.1080/13547500902730680",
language = "English",
volume = "14",
pages = "17--25",
journal = "Biomarkers",
issn = "1354-750X",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect

AU - Gorham, Katrine A

AU - Andersen, Mads Peter Sulbæk

AU - Meinardi, Simone

AU - Delfino, Ralph J

AU - Staimer, Norbert

AU - Tjoa, Thomas

AU - Rowland, F Sherwood

AU - Blake, Donald R

PY - 2009

Y1 - 2009

N2 - The relationship of exhaled ethane and n-pentane to exhaled NO, carbonylated proteins, and indoor/outdoor atmospheric pollutants were examined in order to evaluate ethane and n-pentane as potential markers of airway inflammation and/or oxidative stress. Exhaled NO and carbonylated proteins were found to have no significant associations with either ethane (p = 0.96 and p = 0.81, respectively) or n-pentane (p = 0.44 and 0.28, respectively) when outliers were included. In the case where outliers were removed n-pentane was found to be inversely associated with carbonylated proteins. Exhaled hydrocarbons adjusted for indoor hydrocarbon concentrations were instead found to be positively associated with air pollutants (NO, NO(2) and CO), suggesting pollutant exposure is driving exhaled hydrocarbon concentrations. Given these findings, ethane and n-pentane do not appear to be markers of airway inflammation or oxidative stress.

AB - The relationship of exhaled ethane and n-pentane to exhaled NO, carbonylated proteins, and indoor/outdoor atmospheric pollutants were examined in order to evaluate ethane and n-pentane as potential markers of airway inflammation and/or oxidative stress. Exhaled NO and carbonylated proteins were found to have no significant associations with either ethane (p = 0.96 and p = 0.81, respectively) or n-pentane (p = 0.44 and 0.28, respectively) when outliers were included. In the case where outliers were removed n-pentane was found to be inversely associated with carbonylated proteins. Exhaled hydrocarbons adjusted for indoor hydrocarbon concentrations were instead found to be positively associated with air pollutants (NO, NO(2) and CO), suggesting pollutant exposure is driving exhaled hydrocarbon concentrations. Given these findings, ethane and n-pentane do not appear to be markers of airway inflammation or oxidative stress.

KW - Aged

KW - Aged, 80 and over

KW - Biological Markers

KW - Breath Tests

KW - Ethane

KW - Female

KW - Humans

KW - Male

KW - Pentanes

U2 - 10.1080/13547500902730680

DO - 10.1080/13547500902730680

M3 - Journal article

C2 - 19283520

VL - 14

SP - 17

EP - 25

JO - Biomarkers

JF - Biomarkers

SN - 1354-750X

IS - 1

ER -

ID: 44565349