Effects of casein, whey and soy proteins on volumetric bone density and bone strength in immunocompromised piglets

Research output: Contribution to journalJournal articleResearchpeer-review

Summary:Background and aims: Bone-promoting effect of different proteins in early life, under immunocompromised conditions, is unknown. We investigated effects of milk- and plantderived proteins on bone development in immunocompromised piglets.
Methods: Newborn, colostrum-deprived piglets were assigned to a formula based on either casein (n=11), whey (n=11) or soy (n=10) as the protein source (each 55 g/L), and equal amounts of fat, carbohydrates, calcium and phosphorus.
Results & Conclusion: Despite efforts to sustain immuno-protection (sow serum and antibiotic injections), some piglets became sick and were early euthanised. After 6 days, bone density (peripheral quantitative computed tomography), bone mechanical strength (three-point bending test) and serum insulin-like growth factor-I (sIGF-I) (immunoassay) were measured in the surviving piglets (casein n=5, whey n=9, soy n=5).

Original languageEnglish
Journale - S P E N
Issue number3
Pages (from-to)57-62
Number of pages6
Publication statusPublished - 2007

ID: 8068458