Drosophila as a Model to Study the Link between Metabolism and Cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Documents
- Drosophila as a Model to Study the Link between Metabolism and Cancer
Final published version, 266 KB, PDF document
Cellular metabolism has recently been recognized as a hallmark of cancer. Investigating the origin and effects of the reprogrammed metabolism of tumor cells, and identifying its genetic mediators, will improve our understanding of how these changes contribute to disease progression and may suggest new approaches to therapy. Drosophila melanogaster is emerging as a valuable model to study multiple aspects of tumor formation and malignant transformation. In this review, we discuss the use of Drosophila as model to study how changes in cellular metabolism, as well as metabolic disease, contribute to cancer.
Original language | English |
---|---|
Article number | 15 |
Journal | Journal of Developmental Biology |
Volume | 5 |
Issue number | 4 |
Number of pages | 14 |
DOIs | |
Publication status | Published - Dec 2017 |
- Drosophila, animal model, metabolism, cancer, Warburg effect, obesity, type 2 diabetes
Research areas
Number of downloads are based on statistics from Google Scholar and www.ku.dk
No data available
ID: 188481760