Dietary factors impact on the association between CTSS variants and obesity related traits

Research output: Contribution to journalJournal articleResearchpeer-review

  • Henri Hooton
  • Claus Holst
  • Jorg Hager
  • Francis Rousseau
  • Rikke D Hansen
  • Anne Tjønneland
  • Nina Roswall
  • Daphne L van der A
  • Kim Overvad
  • Marianne Uhre Jakobsen
  • Heiner Boeing
  • Karina Meidtner
  • Domenico Palli
  • Giovanna Masala
  • Nabila Bouatia-Naji
  • Wim H M Saris
  • Edith J M Feskens
  • Nicolas J Wareham
  • Karani S Vimaleswaran
  • Dominique Langin
  • Ruth J F Loos
  • Karine Clément
Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects are influenced by dietary factors--increased by high protein, glycemic index and energy diets.
Original languageEnglish
JournalP L o S One
Issue number7
Pages (from-to)e40394
Publication statusPublished - 2012

ID: 48585741