Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs. / Lilius, Tuomas O.; Blomqvist, Kim; Hauglund, Natalie L.; Liu, Guojun; Stæger, Frederik Filip; Baerentzen, Simone; Du, Ting; Ahlstrom, Fredrik; Backman, Janne T.; Kalso, Eija A.; Rauhala, Pekka, V; Nedergaard, Maiken.

In: Journal of Controlled Release, Vol. 304, 2019, p. 29-38.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Lilius, TO, Blomqvist, K, Hauglund, NL, Liu, G, Stæger, FF, Baerentzen, S, Du, T, Ahlstrom, F, Backman, JT, Kalso, EA, Rauhala, PV & Nedergaard, M 2019, 'Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs', Journal of Controlled Release, vol. 304, pp. 29-38. https://doi.org/10.1016/j.jconrel.2019.05.005

APA

Lilius, T. O., Blomqvist, K., Hauglund, N. L., Liu, G., Stæger, F. F., Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V., & Nedergaard, M. (2019). Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs. Journal of Controlled Release, 304, 29-38. https://doi.org/10.1016/j.jconrel.2019.05.005

Vancouver

Lilius TO, Blomqvist K, Hauglund NL, Liu G, Stæger FF, Baerentzen S et al. Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs. Journal of Controlled Release. 2019;304:29-38. https://doi.org/10.1016/j.jconrel.2019.05.005

Author

Lilius, Tuomas O. ; Blomqvist, Kim ; Hauglund, Natalie L. ; Liu, Guojun ; Stæger, Frederik Filip ; Baerentzen, Simone ; Du, Ting ; Ahlstrom, Fredrik ; Backman, Janne T. ; Kalso, Eija A. ; Rauhala, Pekka, V ; Nedergaard, Maiken. / Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs. In: Journal of Controlled Release. 2019 ; Vol. 304. pp. 29-38.

Bibtex

@article{1112159432684df0913ea9fb0c992372,
title = "Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs",
keywords = "Drug delivery, Glymphatic system, Pharmacokinetics, alpha(2)-adrenergic agonist, Dexmedetomidine, Opioid, Amyloid-beta, Antibody therapy",
author = "Lilius, {Tuomas O.} and Kim Blomqvist and Hauglund, {Natalie L.} and Guojun Liu and St{\ae}ger, {Frederik Filip} and Simone Baerentzen and Ting Du and Fredrik Ahlstrom and Backman, {Janne T.} and Kalso, {Eija A.} and Rauhala, {Pekka, V} and Maiken Nedergaard",
year = "2019",
doi = "10.1016/j.jconrel.2019.05.005",
language = "English",
volume = "304",
pages = "29--38",
journal = "Journal of Controlled Release",
issn = "0168-3659",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

AU - Lilius, Tuomas O.

AU - Blomqvist, Kim

AU - Hauglund, Natalie L.

AU - Liu, Guojun

AU - Stæger, Frederik Filip

AU - Baerentzen, Simone

AU - Du, Ting

AU - Ahlstrom, Fredrik

AU - Backman, Janne T.

AU - Kalso, Eija A.

AU - Rauhala, Pekka, V

AU - Nedergaard, Maiken

PY - 2019

Y1 - 2019

KW - Drug delivery

KW - Glymphatic system

KW - Pharmacokinetics

KW - alpha(2)-adrenergic agonist

KW - Dexmedetomidine

KW - Opioid

KW - Amyloid-beta

KW - Antibody therapy

U2 - 10.1016/j.jconrel.2019.05.005

DO - 10.1016/j.jconrel.2019.05.005

M3 - Journal article

C2 - 31067483

VL - 304

SP - 29

EP - 38

JO - Journal of Controlled Release

JF - Journal of Controlled Release

SN - 0168-3659

ER -

ID: 225380618