Determinants of serum tryptase in a general population: the relationship of serum tryptase to obesity and asthma
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Determinants of serum tryptase in a general population : the relationship of serum tryptase to obesity and asthma. / Fenger, R V; Linneberg, A; Vidal, C; Vizcaino, L; Husemoen, Lise-Lotte; Aadahl, Mette; Gonzalez-Quintela, A.
In: International Archives of Allergy and Immunology, Vol. 157, No. 2, 2012, p. 151-8.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Determinants of serum tryptase in a general population
T2 - the relationship of serum tryptase to obesity and asthma
AU - Fenger, R V
AU - Linneberg, A
AU - Vidal, C
AU - Vizcaino, L
AU - Husemoen, Lise-Lotte
AU - Aadahl, Mette
AU - Gonzalez-Quintela, A
N1 - Copyright © 2011 S. Karger AG, Basel.
PY - 2012
Y1 - 2012
N2 - Recent studies indicate that mast cells are more abundant in the obese state. Total serum tryptase (ST) is a marker of mast cell numbers or activity. Since obesity and asthma have been consistently linked in epidemiological studies, a possible higher mast cell activity in obesity could be a factor between the two conditions. The aim of this study was to investigate determinants of ST and whether a potential association between obesity and allergic respiratory disease would be influenced by levels of ST in obese persons.
AB - Recent studies indicate that mast cells are more abundant in the obese state. Total serum tryptase (ST) is a marker of mast cell numbers or activity. Since obesity and asthma have been consistently linked in epidemiological studies, a possible higher mast cell activity in obesity could be a factor between the two conditions. The aim of this study was to investigate determinants of ST and whether a potential association between obesity and allergic respiratory disease would be influenced by levels of ST in obese persons.
U2 - 10.1159/000327535
DO - 10.1159/000327535
M3 - Journal article
C2 - 21985913
VL - 157
SP - 151
EP - 158
JO - International Archives of Allergy and Immunology
JF - International Archives of Allergy and Immunology
SN - 1018-2438
IS - 2
ER -
ID: 40217515