Detecting the brachyspina mutation

Research output: Patent

This invention relates to methods for the detection of a bovine that is affected by or carrier of brachyspina. It is based on the identification of a 3.3 Kb deletion in the bovine FANCI gene that is shown to cause the brachyspina syndrome. The present invention provides methods and uses for determining whether a bovine is affected by or carrier of brachyspina by analyzing its genomic DNA or its RNA. The methods can be used to perform marker assisted selection or genomic selection for increased fertility in said bovine.

Original languageEnglish
IPCC12Q 1/68 (2006.01)
Patent numberWO 2012/155995 A1
Filing date22/11/2012
Publication statusPublished - 2012

ID: 44582313