Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease. / Feldt-Rasmussen, Ulla; Bliddal, Sofie; Rasmussen, Åse Krogh; Boas, Malene; Hilsted, Linda; Main, Katharina.

In: Journal of Thyroid Research, Vol. 2011, 2011, p. 598712.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Feldt-Rasmussen, U, Bliddal, S, Rasmussen, ÅK, Boas, M, Hilsted, L & Main, K 2011, 'Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease', Journal of Thyroid Research, vol. 2011, pp. 598712. https://doi.org/10.1155/2017/4324130, https://doi.org/10.4061/2011/598712

APA

Feldt-Rasmussen, U., Bliddal, S., Rasmussen, Å. K., Boas, M., Hilsted, L., & Main, K. (2011). Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease. Journal of Thyroid Research, 2011, 598712. https://doi.org/10.1155/2017/4324130, https://doi.org/10.4061/2011/598712

Vancouver

Feldt-Rasmussen U, Bliddal S, Rasmussen ÅK, Boas M, Hilsted L, Main K. Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease. Journal of Thyroid Research. 2011;2011:598712. https://doi.org/10.1155/2017/4324130, https://doi.org/10.4061/2011/598712

Author

Feldt-Rasmussen, Ulla ; Bliddal, Sofie ; Rasmussen, Åse Krogh ; Boas, Malene ; Hilsted, Linda ; Main, Katharina. / Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease. In: Journal of Thyroid Research. 2011 ; Vol. 2011. pp. 598712.

Bibtex

@article{63fe6c0ad18447b3ae58311e0b9091d7,
title = "Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease",
abstract = "Physiological changes during gestation are important to be aware of in measurement and interpretation of thyroid function tests in women with autoimmune thyroid diseases. Thyroid autoimmune activity is decreasing in pregnancy. Measurement of serum TSH is the first-line screening variable for thyroid dysfunction also in pregnancy. However, using serum TSH for control of treatment of maternal thyroid autoimmunity infers a risk for compromised foetal development. Peripheral thyroid hormone values are highly different among laboratories, and there is a need for laboratory-specific gestational age-related reference ranges. Equally important, the intraindividual variability of the thyroid hormone measurements is much narrower than the interindividual variation (reflecting the reference interval). The best laboratory assessment of thyroid function is a free thyroid hormone estimate combined with TSH. Measurement of antithyroperoxidase and/or TSH receptor antibodies adds to the differential diagnosis of autoimmune and nonautoimmune thyroid diseases.",
author = "Ulla Feldt-Rasmussen and Sofie Bliddal and Rasmussen, {{\AA}se Krogh} and Malene Boas and Linda Hilsted and Katharina Main",
year = "2011",
doi = "10.1155/2017/4324130",
language = "English",
volume = "2011",
pages = "598712",
journal = "Journal of Thyroid Research",
issn = "2042-0072",
publisher = "Hindawi Publishing Corporation",

}

RIS

TY - JOUR

T1 - Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease

AU - Feldt-Rasmussen, Ulla

AU - Bliddal, Sofie

AU - Rasmussen, Åse Krogh

AU - Boas, Malene

AU - Hilsted, Linda

AU - Main, Katharina

PY - 2011

Y1 - 2011

N2 - Physiological changes during gestation are important to be aware of in measurement and interpretation of thyroid function tests in women with autoimmune thyroid diseases. Thyroid autoimmune activity is decreasing in pregnancy. Measurement of serum TSH is the first-line screening variable for thyroid dysfunction also in pregnancy. However, using serum TSH for control of treatment of maternal thyroid autoimmunity infers a risk for compromised foetal development. Peripheral thyroid hormone values are highly different among laboratories, and there is a need for laboratory-specific gestational age-related reference ranges. Equally important, the intraindividual variability of the thyroid hormone measurements is much narrower than the interindividual variation (reflecting the reference interval). The best laboratory assessment of thyroid function is a free thyroid hormone estimate combined with TSH. Measurement of antithyroperoxidase and/or TSH receptor antibodies adds to the differential diagnosis of autoimmune and nonautoimmune thyroid diseases.

AB - Physiological changes during gestation are important to be aware of in measurement and interpretation of thyroid function tests in women with autoimmune thyroid diseases. Thyroid autoimmune activity is decreasing in pregnancy. Measurement of serum TSH is the first-line screening variable for thyroid dysfunction also in pregnancy. However, using serum TSH for control of treatment of maternal thyroid autoimmunity infers a risk for compromised foetal development. Peripheral thyroid hormone values are highly different among laboratories, and there is a need for laboratory-specific gestational age-related reference ranges. Equally important, the intraindividual variability of the thyroid hormone measurements is much narrower than the interindividual variation (reflecting the reference interval). The best laboratory assessment of thyroid function is a free thyroid hormone estimate combined with TSH. Measurement of antithyroperoxidase and/or TSH receptor antibodies adds to the differential diagnosis of autoimmune and nonautoimmune thyroid diseases.

U2 - 10.1155/2017/4324130

DO - 10.1155/2017/4324130

M3 - Journal article

VL - 2011

SP - 598712

JO - Journal of Thyroid Research

JF - Journal of Thyroid Research

SN - 2042-0072

ER -

ID: 40146219