Betydningen af mikroribonukleinsyre for sygdomsudvikling
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Betydningen af mikroribonukleinsyre for sygdomsudvikling. / Widjaya, Budiman; Seidelin, Jakob Benedict; Olsen, Jørgen; Nielsen, Ole Haagen.
In: Ugeskrift for Laeger, Vol. 171, No. 47, 16.11.2009, p. 3441-4.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Betydningen af mikroribonukleinsyre for sygdomsudvikling
AU - Widjaya, Budiman
AU - Seidelin, Jakob Benedict
AU - Olsen, Jørgen
AU - Nielsen, Ole Haagen
PY - 2009/11/16
Y1 - 2009/11/16
N2 - MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) consisting of approximately 22 nucleotides which are believed to control posttranscriptional gene expression by targeting messenger RNA (mRNA) either by degradation or silencing. This article focuses on the importance of miRNAs in different diseases. There are observations or even evidence that miRNA is involved in the pathogenesis of diseases such as autoimmune, cancer, cardio-vascular, metabolic and infectious diseases. The manipulation of the expression of one or several specific miRNAs could prove to be a promising treatment option, and may improve diagnostics and therapeutics in future patient care.
AB - MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) consisting of approximately 22 nucleotides which are believed to control posttranscriptional gene expression by targeting messenger RNA (mRNA) either by degradation or silencing. This article focuses on the importance of miRNAs in different diseases. There are observations or even evidence that miRNA is involved in the pathogenesis of diseases such as autoimmune, cancer, cardio-vascular, metabolic and infectious diseases. The manipulation of the expression of one or several specific miRNAs could prove to be a promising treatment option, and may improve diagnostics and therapeutics in future patient care.
KW - Animals
KW - Cardiovascular Diseases
KW - Diabetes Mellitus
KW - Gene Expression Regulation
KW - Hepatitis C
KW - Humans
KW - Inflammatory Bowel Diseases
KW - MicroRNAs
KW - Neoplasms
KW - English Abstract
KW - Journal Article
M3 - Tidsskriftartikel
C2 - 19925731
VL - 171
SP - 3441
EP - 3444
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 47
ER -
ID: 173051293