Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study
Research output: Contribution to journal › Journal article › Research › peer-review
Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS) have shown higher predictive value for proarrhythmia with beat-to-beat variability of repolarization duration (BVR) when compared with QT intervals. Here, we evaluate variability of QT intervals in patients with a history of drug-induced long QT syndrome (dLQTS) and TdP in absence of a mutation in any of the major LQTS genes.
|Journal||European Heart Journal|
|Number of pages||6|
|Publication status||Published - Jan 2008|
- Aged, Arrhythmias, Cardiac, Case-Control Studies, Disease Susceptibility, Electrocardiography, Female, Heart Rate, Humans, Long QT Syndrome, Male, Middle Aged, Pilot Projects, Predictive Value of Tests, Torsades de Pointes