Atrial secretion of B-type natriuretic peptide

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Atrial secretion of B-type natriuretic peptide. / Goetze, Jens Peter; Friis-Hansen, Lennart; Rehfeld, Jens F; Nilsson, Brian; Svendsen, Jesper Hastrup.

In: European Heart Journal, Vol. 27, No. 14, 2006, p. 1648-50.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Goetze, JP, Friis-Hansen, L, Rehfeld, JF, Nilsson, B & Svendsen, JH 2006, 'Atrial secretion of B-type natriuretic peptide', European Heart Journal, vol. 27, no. 14, pp. 1648-50. https://doi.org/10.1093/eurheartj/ehl109

APA

Goetze, J. P., Friis-Hansen, L., Rehfeld, J. F., Nilsson, B., & Svendsen, J. H. (2006). Atrial secretion of B-type natriuretic peptide. European Heart Journal, 27(14), 1648-50. https://doi.org/10.1093/eurheartj/ehl109

Vancouver

Goetze JP, Friis-Hansen L, Rehfeld JF, Nilsson B, Svendsen JH. Atrial secretion of B-type natriuretic peptide. European Heart Journal. 2006;27(14):1648-50. https://doi.org/10.1093/eurheartj/ehl109

Author

Goetze, Jens Peter ; Friis-Hansen, Lennart ; Rehfeld, Jens F ; Nilsson, Brian ; Svendsen, Jesper Hastrup. / Atrial secretion of B-type natriuretic peptide. In: European Heart Journal. 2006 ; Vol. 27, No. 14. pp. 1648-50.

Bibtex

@article{e32b7dd0a30011df928f000ea68e967b,
title = "Atrial secretion of B-type natriuretic peptide",
abstract = "In the normal heart, the endocrine capacity resides in the atria. Atrial myocytes express and secrete natriuretic hormones that regulate fluid homeostasis and blood pressure. But in ventricular disease, atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) gene expression is also activated in ventricular myocytes. Plasma concentrations of natriuretic peptides and their biosynthetic precursors are accordingly increased in patients with marked ventricular dysfunction. In contrast, atrial peptide secretion in ventricular disease has received less attention, and our present understanding of the endocrine atria during ventricular dysfunction is still scarce. Although ventricular disease and increased circulating concentrations are associated, it does not entail that the ventricle is the sole or even the main source in all types of heart disease. Clearly, the endocrine atria are also active in heart failure. Plasma measurement of cardiac natriuretic peptides and their molecular precursors can perhaps help us to discriminate when, where and how.",
author = "Goetze, {Jens Peter} and Lennart Friis-Hansen and Rehfeld, {Jens F} and Brian Nilsson and Svendsen, {Jesper Hastrup}",
note = "Keywords: Atrial Fibrillation; Heart Atria; Heart Failure; Humans; Microscopy, Confocal; Myocytes, Cardiac; Natriuretic Peptide, Brain",
year = "2006",
doi = "10.1093/eurheartj/ehl109",
language = "English",
volume = "27",
pages = "1648--50",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "14",

}

RIS

TY - JOUR

T1 - Atrial secretion of B-type natriuretic peptide

AU - Goetze, Jens Peter

AU - Friis-Hansen, Lennart

AU - Rehfeld, Jens F

AU - Nilsson, Brian

AU - Svendsen, Jesper Hastrup

N1 - Keywords: Atrial Fibrillation; Heart Atria; Heart Failure; Humans; Microscopy, Confocal; Myocytes, Cardiac; Natriuretic Peptide, Brain

PY - 2006

Y1 - 2006

N2 - In the normal heart, the endocrine capacity resides in the atria. Atrial myocytes express and secrete natriuretic hormones that regulate fluid homeostasis and blood pressure. But in ventricular disease, atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) gene expression is also activated in ventricular myocytes. Plasma concentrations of natriuretic peptides and their biosynthetic precursors are accordingly increased in patients with marked ventricular dysfunction. In contrast, atrial peptide secretion in ventricular disease has received less attention, and our present understanding of the endocrine atria during ventricular dysfunction is still scarce. Although ventricular disease and increased circulating concentrations are associated, it does not entail that the ventricle is the sole or even the main source in all types of heart disease. Clearly, the endocrine atria are also active in heart failure. Plasma measurement of cardiac natriuretic peptides and their molecular precursors can perhaps help us to discriminate when, where and how.

AB - In the normal heart, the endocrine capacity resides in the atria. Atrial myocytes express and secrete natriuretic hormones that regulate fluid homeostasis and blood pressure. But in ventricular disease, atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) gene expression is also activated in ventricular myocytes. Plasma concentrations of natriuretic peptides and their biosynthetic precursors are accordingly increased in patients with marked ventricular dysfunction. In contrast, atrial peptide secretion in ventricular disease has received less attention, and our present understanding of the endocrine atria during ventricular dysfunction is still scarce. Although ventricular disease and increased circulating concentrations are associated, it does not entail that the ventricle is the sole or even the main source in all types of heart disease. Clearly, the endocrine atria are also active in heart failure. Plasma measurement of cardiac natriuretic peptides and their molecular precursors can perhaps help us to discriminate when, where and how.

U2 - 10.1093/eurheartj/ehl109

DO - 10.1093/eurheartj/ehl109

M3 - Journal article

C2 - 16785247

VL - 27

SP - 1648

EP - 1650

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 14

ER -

ID: 21258927