An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine. / Nielsen, Ditte Dencker; Weikop, Pia; Sørensen, Gunnar; Woldbye, David P D; Wörtwein, Gitta; Wess, Jürgen; Fink-Jensen, Anders.

In: Psychopharmacology, Vol. 224, No. 2, 2012, p. 277-87.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nielsen, DD, Weikop, P, Sørensen, G, Woldbye, DPD, Wörtwein, G, Wess, J & Fink-Jensen, A 2012, 'An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine', Psychopharmacology, vol. 224, no. 2, pp. 277-87. https://doi.org/10.1007/s00213-012-2751-8

APA

Nielsen, D. D., Weikop, P., Sørensen, G., Woldbye, D. P. D., Wörtwein, G., Wess, J., & Fink-Jensen, A. (2012). An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine. Psychopharmacology, 224(2), 277-87. https://doi.org/10.1007/s00213-012-2751-8

Vancouver

Nielsen DD, Weikop P, Sørensen G, Woldbye DPD, Wörtwein G, Wess J et al. An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine. Psychopharmacology. 2012;224(2):277-87. https://doi.org/10.1007/s00213-012-2751-8

Author

Nielsen, Ditte Dencker ; Weikop, Pia ; Sørensen, Gunnar ; Woldbye, David P D ; Wörtwein, Gitta ; Wess, Jürgen ; Fink-Jensen, Anders. / An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine. In: Psychopharmacology. 2012 ; Vol. 224, No. 2. pp. 277-87.

Bibtex

@article{81711a0520924d6ea87b725296bfcb77,
title = "An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine",
abstract = "The mesostriatal dopamine system plays a key role in mediating the reinforcing effects of psychostimulant drugs like cocaine. The muscarinic M(4) acetylcholine receptor subtype is centrally involved in the regulation of dopamine release in striatal areas. Consequently, striatal M(4) receptors could be a novel target for modulating psychostimulant effects of cocaine.",
author = "Nielsen, {Ditte Dencker} and Pia Weikop and Gunnar S{\o}rensen and Woldbye, {David P D} and Gitta W{\"o}rtwein and J{\"u}rgen Wess and Anders Fink-Jensen",
year = "2012",
doi = "10.1007/s00213-012-2751-8",
language = "English",
volume = "224",
pages = "277--87",
journal = "Psychopharmacology",
issn = "0033-3158",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine

AU - Nielsen, Ditte Dencker

AU - Weikop, Pia

AU - Sørensen, Gunnar

AU - Woldbye, David P D

AU - Wörtwein, Gitta

AU - Wess, Jürgen

AU - Fink-Jensen, Anders

PY - 2012

Y1 - 2012

N2 - The mesostriatal dopamine system plays a key role in mediating the reinforcing effects of psychostimulant drugs like cocaine. The muscarinic M(4) acetylcholine receptor subtype is centrally involved in the regulation of dopamine release in striatal areas. Consequently, striatal M(4) receptors could be a novel target for modulating psychostimulant effects of cocaine.

AB - The mesostriatal dopamine system plays a key role in mediating the reinforcing effects of psychostimulant drugs like cocaine. The muscarinic M(4) acetylcholine receptor subtype is centrally involved in the regulation of dopamine release in striatal areas. Consequently, striatal M(4) receptors could be a novel target for modulating psychostimulant effects of cocaine.

U2 - 10.1007/s00213-012-2751-8

DO - 10.1007/s00213-012-2751-8

M3 - Journal article

C2 - 22648127

VL - 224

SP - 277

EP - 287

JO - Psychopharmacology

JF - Psychopharmacology

SN - 0033-3158

IS - 2

ER -

ID: 48447898