Adhesion molecules in inflammatory and neoplastic intestinal diseases

Research output: Contribution to journalReviewResearchpeer-review

Adhesion molecules participate in a broad variety of biological processes, i.e. tumor progression and inflammation, through their involvement in cell-to-cell interactions and immunoinflammatory cell migration. This review describes the basic properties of adhesion molecules with reference to inflammatory bowel disease and colorectal carcinoma. Accumulating data suggest that adhesion molecules could be pathogenetically pertinent to other gastrointestinal disorders such as celiac disease (nontropical sprue) and gastroduodenal ulcer. Future therapeutic approaches in inflammatory and malignant disorders may possibly be development of principles targeting adhesion molecules.

Original languageEnglish
JournalDigestive Diseases
Issue number5
Pages (from-to)322-36
Number of pages15
Publication statusPublished - 1 Sep 1995

    Research areas

  • Cell Adhesion Molecules/physiology, Colorectal Neoplasms/physiopathology, Humans, Inflammation/physiopathology, Inflammatory Bowel Diseases/physiopathology

ID: 218727046