Actomyosin organisation for adhesion, spreading, growth and movement in chick fibroblasts.

Research output: Contribution to journalJournal articleResearchpeer-review

Examination of the actomyosin structures and their relation to adhesion, movement and growth in the first fibroblasts migrating from chick heart explants shows striking differences with fibroblasts adapted to grow in culture. The latter have focal adhesions which seem to immobilize them for anchorage-dependent growth, rather than facilitate their movement. The fibroblasts specialized for movement from the explants, though equally well spread, make contact with substratum through extensive areas of relatively unspecialized membrane, have less well developed stress fibres and a low growth rate.
Original languageEnglish
JournalCell Biology International Reports
Issue number5
Pages (from-to)431-9
Number of pages8
Publication statusPublished - 1979

Bibliographical note

Keywords: Actomyosin; Animals; Antigens; Cell Adhesion; Cell Division; Cell Movement; Cells, Cultured; Chick Embryo; Cytoskeleton; Fibroblasts; Fluorescent Antibody Technique; Microscopy, Electron; Microscopy, Interference; Myocardium

ID: 5168005