A proteomics sample metadata representation for multiomics integration and big data analysis
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- A proteomics sample metadata representation for multiomics integration and big data analysis
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The amount of public proteomics data is rapidly increasing but there is no standardized format to describe the sample metadata and their relationship with the dataset files in a way that fully supports their understanding or reanalysis. Here we propose to develop the transcriptomics data format MAGE-TAB into a standard representation for proteomics sample metadata. We implement MAGE-TAB-Proteomics in a crowdsourcing project to manually curate over 200 public datasets. We also describe tools and libraries to validate and submit sample metadata-related information to the PRIDE repository. We expect that these developments will improve the reproducibility and facilitate the reanalysis and integration of public proteomics datasets.
Original language | English |
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Article number | 5854 |
Journal | Nature Communications |
Volume | 12 |
Issue number | 1 |
Number of pages | 8 |
ISSN | 2041-1723 |
DOIs | |
Publication status | Published - 2021 |
Bibliographical note
Publisher Copyright:
© 2021, The Author(s).
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