Vilhelm Bohr
Affiliate professor
Molecular Aging Program
Panum Instituttet, Blegdamsvej 3, 2200 København N, 07 Bygning 7, Building: 07-3-13
Member of:
Web: Center for Healthy Aging
Web Track 3: Individualized health
Toward understanding genomic instability, mitochondrial dysfunction and aging
Fakouri, N. B., Hou, Y., Demarest, T. G., Christiansen, L. S., Okur, M. N., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2019, In: F E B S Journal. 286, 6, p. 1058-1073 16 p.Research output: Contribution to journal › Review › peer-review
- Published
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.Research output: Contribution to journal › Journal article › peer-review
- Published
The role of RecQ helicases in non-homologous end-joining
Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.Research output: Contribution to journal › Review › peer-review
- Published
The role of DNA base excision repair in brain homeostasis and disease
Akbari, M., Morevati, M., Croteau, D. & Bohr, Vilhelm, Aug 2015, In: DNA Repair. 32, p. 172-9 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells
de Souza-Pinto, N. C., Maynard, S., Hashiguchi, K., Hu, J., Muftuoglu, M. & Bohr, Vilhelm, Aug 2009, In: Molecular and Cellular Biology. 29, 16, p. 4441-54 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The mitochondrial transcription factor A functions in mitochondrial base excision repair
Canugovi, C., Maynard, S., Bayne, A. V., Sykora, P., Tian, J., de Souza-Pinto, N. C., Croteau, D. L. & Bohr, Vilhelm, 5 Oct 2010, In: DNA Repair. 9, 10, p. 1080-9 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The involvement of human RECQL4 in DNA double-strand break repair
Singh, D. K., Karmakar, P., Aamann, M. D., Schurman, S. H., May, A., Croteau, D. L., Burks, L., Plon, S. E. & Bohr, Vilhelm, 1 Jun 2010, In: Aging Cell. 9, 3, p. 358-71 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients
Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The cGAS-STING signaling pathway is modulated by urolithin A
Madsen, Helena Borland, Park, J. H., Chu, X., Hou, Y., Li, Zhiquan, Rasmussen, Lene Juel, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2024, In: Mechanisms of Ageing and Development. 217, 11 p., 111897.Research output: Contribution to journal › Journal article › peer-review
- Published
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › peer-review
- Published
The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Madsen, Helena Borland, Pease, L. I., Scanlan, R. L., Akbari, M., Rasmussen, Lene Juel, Shanley, D. P. & Bohr, Vilhelm, 2023, In: Frontiers in Aging Neuroscience. 15, 17 p., 1290681.Research output: Contribution to journal › Journal article › peer-review
- Published
Telomerer--begyndelsen og enden
Bohr, Vilhelm, 4 Oct 2010, In: Ugeskrift for Laeger. 172, 40, p. 2744Research output: Contribution to journal › Journal article › peer-review
- Published
Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases
Popuri, V., Croteau, D. L. & Bohr, Vilhelm, 4 Jun 2010, In: DNA Repair. 9, 6, p. 636-42 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › peer-review
- Published
Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells
Akbari, M., Sykora, P. & Bohr, Vilhelm, 10 Aug 2015, In: Scientific Reports. 5, 8 p., 12876 .Research output: Contribution to journal › Journal article › peer-review
- Published
Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome
Okur, M. N., Mao, B., Kimura, R., Haraczy, S., Fitzgerald, T., Edwards-Hollingsworth, K., Tian, J., Osmani, W., Croteau, D. L., Kelley, M. W. & Bohr, Vilhelm, Jan 2020, In: npj Aging and Mechanisms of Disease. 6, 10 p., 1.Research output: Contribution to journal › Journal article › peer-review
- Published
Sarcopenia, Aging and Prospective Interventional Strategies
Waltz, T. B., Fivenson, E. M., Morevati, M., Li, C., Becker, K. G., Bohr, Vilhelm & Fang, E. F., 2018, In: Current Medicinal Chemistry. 25, 40, p. 5588-5596 9 p.Research output: Contribution to journal › Review › peer-review
- Published
Salidroside promotes healthy longevity by interfering with HSP90 activity
Zhang, J., Li, Zhiquan, Song, J., Zhou, L., Chen, X., Ge, W., Dong, T., Luo, Y., Mao, T., Li, Z., Tan, D., Rasmussen, Lene Juel, Bohr, Vilhelm, Tong, X. & Dai, F., 2024, In: GeroScience. 46, p. 1641–1655 15 p.Research output: Contribution to journal › Journal article › peer-review
- Published
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
McCord, R. A., Michishita, E., Hong, T., Berber, E., Boxer, L. D., Kusumoto, R., Guan, S., Shi, X., Gozani, O., Burlingame, A. L., Bohr, Vilhelm & Chua, K. F., 1 Jan 2009, In: Aging. 1, 1, p. 109-21 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Roles of Werner syndrome protein in protection of genome integrity
Rossi, M. L., Ghosh, A. K. & Bohr, Vilhelm, 2 Mar 2010, In: DNA Repair. 9, 3, p. 331-44 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Roles of NAD+ in Health and Aging
Lautrup, S., Hou, Y., Fang, E. F. & Bohr, Vilhelm, 2024, In: Cold Spring Harbor Perspectives in Medicine. 14, 1, 27 p., a041193.Research output: Contribution to journal › Journal article › peer-review
- Published
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.Research output: Contribution to journal › Journal article › peer-review
- Published
Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
Soerensen, M., Dato, S., Christensen, K., McGue, M., Stevnsner, T. V., Bohr, Vilhelm & Christiansen, L., 1 Dec 2010, In: Aging Cell. 9, 6, p. 1010-7 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
Maynard, S., Keijzers, G., Gram, M., Desler, Claus, Bendix, L., Budtz-Joergensen, Esben, Molbo, Drude, Croteau, D. L., Osler, Merete, Stevnsner, T. V., Rasmussen, Lene Juel, Dela, Flemming, Avlund, K. & Bohr, Vilhelm, 30 Nov 2013, In: Aging. p. 850-864 15 p.Research output: Contribution to journal › Journal article › peer-review
- Published
RecQ dysfunction contributes to social and depressive-like behavior and affects aldolase activity in mice
Hou, Y., Park, J. H., Dan, X., Chu, X., Yang, B., Hussain, M., Croteau, D. L. & Bohr, Vilhelm, 2023, In: Neurobiology of Disease. 180, 11 p., 106092.Research output: Contribution to journal › Journal article › peer-review
ID: 4975983
Most downloads
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281
downloads
Mitochondria in the signaling pathways that control longevity and health span
Research output: Contribution to journal › Review › peer-review
Published -
277
downloads
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Research output: Contribution to journal › Journal article › peer-review
Published -
248
downloads
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Research output: Contribution to journal › Journal article › peer-review
Published