Vilhelm Bohr

Vilhelm Bohr

Affiliate professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, Guido, Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In : D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

    Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In : Journal of Visualized Experiments. 129, e56301.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In : Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, Morten, Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, Linda Hildegard, Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L., De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In : Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, Linda Hildegard, Dec 2016, In : Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In : The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. A research agenda for aging in China in the 21st century

    Fang, E. F., Scheibye-Knudsen, Morten, Jahn, H. J., Li, J., Ling, L., Guo, H., Zhu, X., Preedy, V., Lu, H., Bohr, Vilhelm, Chan, W. Y., Liu, Y. & Ng, T. B., Nov 2015, In : Ageing Research Reviews. 24, Pt B, p. 197-205 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Acetylation regulates WRN catalytic activities and affects base excision DNA repair

    Muftuoglu, M., Kusumoto, R., Speina, E., Beck, G., Cheng, W. & Bohr, Vilhelm, Jan 2008, In : P L o S One. 3, 4, p. e1918

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In : Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Ageing as a risk factor for neurodegenerative disease

    Hou, Y., Dan, X., Babbar, M., Wei, Y., Hasselbalch, Steen, Croteau, D. L. & Bohr, Vilhelm, 2019, In : Nature Reviews. Neurology. 15, 10, p. 565-581 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Aging, longevity and health

    Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In : Mechanisms of Ageing and Development. p. 522-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Aprataxin localizes to mitochondria and preserves mitochondrial function

    Sykora, P., Croteau, D. L., Bohr, Vilhelm & Wilson, D. M., 3 May 2011, In : Proceedings of the National Academy of Sciences USA (PNAS). 108, 18, p. 7437-42 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance

    Maynard, S., Keijzers, Guido, Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In : Acta Physiologica (Print). 213, 1, p. 156-170 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Base excision repair activities differ in human lung cancer cells and corresponding normal controls

    Karahalil, B., Bohr, Vilhelm & De Souza-Pinto, N. C., 1 Dec 2010, In : Anticancer Research. 30, 12, p. 4963-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Base excision repair of oxidative DNA damage and association with cancer and aging

    Maynard, S., Schurman, S. H., Harboe, C., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2009, In : Carcinogenesis. 30, 1, p. 2-10 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

    Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, Guido, Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In : DNA Repair. 10, 1, p. 73-86 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Bohr på ny

    Bohr, Vilhelm, Bohr, T., Topsøe, H., Bruun, L., Knudsen, H., Nielsen, H., Aaserud, F., Grandin, K., von Bülow, H., Kragh, H., Andersen, Anja C., Mølmer, K., Favrholdt, D., Faye, J. & Zinkernagel, H., 2 May 2013, København: Forlaget Epsilon.Dk.

    Research output: Book/ReportBookCommunication

  18. Published

    Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

    Aamann, M. D., Hvitby, C. P., Popuri, V., Muftuoglu, M., Lemminger, L. P. B., Skeby, C. K., Keijzers, Guido, Ahn, B., Bjørås, M., Bohr, Vilhelm & Stevnsner, T. V., Jan 2014, In : Mechanisms of Ageing and Development. 135, p. 1-14 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In : Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, Morten, Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. ,. I., Brosh, R. M. ,. J., Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In : National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging

    Lee, J., Demarest, T. G., Babbar, M., Kim, E. W., Okur, M. N., De, S., Croteau, D. L. & Bohr, Vilhelm, 2019, In : Nucleic Acids Research. 47, 16, p. 8548-8562

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy

    Scheibye-Knudsen, M., Ramamoorthy, M., Sykora, P., Maynard, S., Lin, P., Minor, R. K., Wilson, D. M., Cooper, M., Spencer, R., de Cabo, R., Croteau, D. L. & Bohr, Vilhelm, Apr 2012, In : The Journal of Experimental Medicine. 209, 4, p. 855-69 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

    Aamann, M. D., Sorensen, M. M., Hvitby, C. P., Berquist, B. R., Muftuoglu, M., Tian, J., de Souza-Pinto, N. C., Scheibye-Knudsen, M., Wilson, D. M., Stevnsner, T. V. & Bohr, Vilhelm, 1 Jul 2010, In : The FASEB Journal. 24, 7, p. 2334-46 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase

    Muftuoglu, M., de Souza-Pinto, N. C., Dogan, A., Aamann, M., Stevnsner, T., Rybanska, I., Kirkali, G., Dizdaroglu, M. & Bohr, Vilhelm, Apr 2009, In : Journal of Biological Chemistry. 284, 14, p. 9270-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding

    Rossi, M. L., Ghosh, A. K., Kulikowicz, T., Croteau, D. L. & Bohr, Vilhelm, 1 Jul 2010, In : DNA Repair. 9, 7, p. 796-804 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders

    Scheibye-Knudsen, Morten, Fang, E. F., Croteau, D. L. & Bohr, Vilhelm, 2014, In : Autophagy. 10, 8, p. 1468-1469 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

    Kusumoto-Matsuo, R., Opresko, P. L., Ramsden, D., Tahara, H. & Bohr, Vilhelm, 1 May 2010, In : Aging. 2, 5, p. 274-84 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    DNA Damage, DNA Repair, Aging, and Neurodegeneration

    Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In : Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    DNA Repair and the Accumulation of Oxidatively Damaged DNA Are Affected by Fruit Intake in Mice

    Croteau, D. L., de Souza-Pinto, N. C., Harboe, C., Keijzers, Guido, Zhang, Y., Becker, K., Sheng, S. & Bohr, Vilhelm, Dec 2010, In : Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 65, 12, p. 1300-1311 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population

    Rasmussen, Lene Juel, Shiloh, Y., Bergersen, Linda Hildegard, Sander, M., Bohr, Vilhelm & Tønjum, T., Oct 2013, In : Mechanisms of Ageing and Development. 134, 10, p. 427-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    DNA polymerase beta participates in mitochondrial DNA repair

    Sykora, P., Kanno, S., Akbari, Mansour, Kulikowicz, T., Baptiste, B. A., Leandro, G. S., Lu, H., Tian, J., May, A., Becker, K. A., Croteau, D. L., Wilson, D. M., Sobol, R. W., Yasui, A. & Bohr, Vilhelm, Aug 2017, In : Molecular and Cellular Biology. 37, 16, e00237-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    DNA repair deficiency in neurodegeneration

    Jeppesen, D. K., Bohr, Vilhelm & Stevnsner, T. V., 30 Apr 2011, In : Progress in Neurobiology. 94, 2, p. 166-200 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

    Maynard, S., Hejl, Anne-Mette, Dinh, T. T. S., Keijzers, Guido, Hansen, Åse Marie, Madsen, Claus Desler, Moreno-Villanueva, M., Bürkle, A., Rasmussen, Lene Juel, Waldemar, Gunhild & Bohr, Vilhelm, Oct 2015, In : Aging. 7, 10, p. 793-815 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction

    Fang, E. F., Scheibye-Knudsen, M., Brace, L. E., Kassahun, H., SenGupta, T., Nilsen, H., Mitchell, J. R., Croteau, D. L. & Bohr, Vilhelm, 8 May 2014, In : Cell. 157, 4, p. 882-96 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms

    Massip, L., Garand, C., Labbé, A., Perreault, E., Turaga, R. V. N., Bohr, Vilhelm & Lebel, M., 11 Mar 2010, In : Oncogene. 29, 10, p. 1486-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

    Li, X., Fang, E. F., Scheibye-Knudsen, Morten, Cui, H., Qiu, L., Li, J., He, Y., Huang, Jing, Bohr, Vilhelm, Ng, T. B. & Guo, H., 2014, In : Scientific Reports. 4, 6434.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells

    Zheng, Jin, Croteau, D. L., Bohr, Vilhelm & Akbari, Mansour, 2019, In : Nucleic Acids Research. 47, 8, p. 4086–4110

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In : European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Earl R. Stadtman

    Levine, R. L. & Bohr, Vilhelm, 1 Jan 2010, In : Mechanisms of Ageing and Development. 131, 1, p. 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Emerging Antitumor Activities of the Bitter Melon (Momordica charantia)

    Fang, E. F., Froetscher, L., Scheibye-Knudsen, Morten, Bohr, Vilhelm, Wong, J. H. & Ng, T. B., 2019, In : Current Protein and Peptide Science. 20, 3, p. 296-301 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions

    Liu, D., Croteau, D. L., Souza-Pinto, N., Pitta, M., Tian, J., Wu, C., Jiang, H., Mustafa, K., Keijzers, Guido, Bohr, Vilhelm & Mattson, M. P., Feb 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 680-692 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1

    Rhee, D. B., Ghosh, A., Lu, J., Bohr, Vilhelm & Liu, Y., 2 Jan 2011, In : DNA Repair. 10, 1, p. 34-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population

    Berquist, B. R., Singh, D. K., Fan, J., Kim, D., Gillenwater, E., Kulkarni, A., Bohr, Vilhelm, Ackerman, E. J., Tomkinson, A. E. & Wilson, D. M., 1 Aug 2010, In : Nucleic Acids Symposium Series. 38, 15, p. 5023-35 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Genome instability in Alzheimer disease

    Hou, Y., Song, H., Croteau, D. L., Akbari, Mansour & Bohr, Vilhelm, Jan 2017, In : Mechanisms of Ageing and Development. 161, part A, p. 83-94 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

    Zheng, Jin, Akbari, Mansour, Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In : Acta Neuropathologica Communications. 8, 1, 23 p., 25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Human RECQL5beta stimulates flap endonuclease 1

    Speina, E., Dawut, L., Hedayati, M., Wang, Z., May, A., Schwendener, S., Janscak, P., Croteau, D. L. & Bohr, Vilhelm, 1 May 2010, In : Nucleic Acids Symposium Series. 38, 9, p. 2904-16 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Human RecQL4 helicase plays critical roles in prostate carcinogenesis

    Su, Y., Meador, J. A., Calaf, G. M., Proietti De-Santis, L., Zhao, Y., Bohr, Vilhelm & Balajee, A. S., 15 Nov 2010, In : Cancer Research. 70, 22, p. 9207-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Human embryonic stem cells have enhanced repair of multiple forms of DNA damage

    Maynard, S., Swistowska, A. M., Lee, J. W., Liu, Y., Liu, S., Da Cruz, A. B., Rao, M., de Souza-Pinto, N. C., Zeng, X. & Bohr, Vilhelm, 1 Sep 2008, In : Stem Cells. 26, 9, p. 2266-74 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Keijzers, Guido, Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In : Bioscience Reports. 35, 3, 13 p., e00206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Impact papers on aging in 2009

    Blagosklonny, M. V., Campisi, J., Sinclair, D. A., Bartke, A., Blasco, M. A., Bonner, W. M., Bohr, Vilhelm, Brosh, R. M., Brunet, A., Depinho, R. A., Donehower, L. A., Finch, C. E., Finkel, T., Gorospe, M., Gudkov, A. V., Hall, M. N., Hekimi, S., Helfand, S. L., Karlseder, J., Kenyon, C., Kroemer, G., Longo, V., Nussenzweig, A., Osiewacz, H. D., Peeper, D. S., Rando, T. A., Rudolph, K. L., Sassone-Corsi, P., Serrano, M., Sharpless, N. E., Skulachev, V. P., Tilly, J. L., Tower, J., Verdin, E. & Vijg, J., 1 Mar 2010, In : Aging. 2, 3, p. 111-21 11 p.

    Research output: Contribution to journalReviewResearch

Previous 1 2 Next

ID: 4975983