Vilhelm Bohr
Affiliate professor
Molecular Aging Program
Mærsk Tårnet, Building: 7.3.40
2200 København N
Member of:
Web: Center for Healthy Aging
Web Track 3: Individualized health
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Mitochondrial helicases and mitochondrial genome maintenance
de Souza-Pinto, N. C., Aamann, M. D., Kulikowicz, T., Stevnsner, T. V. & Bohr, Vilhelm, 2010, In : Mechanisms of Ageing and Development. 131, 7-8, p. 503-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells
de Souza-Pinto, N. C., Maynard, S., Hashiguchi, K., Hu, J., Muftuoglu, M. & Bohr, Vilhelm, Aug 2009, In : Molecular and Cellular Biology. 29, 16, p. 4441-54 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells
Zheng, Jin, Croteau, D. L., Bohr, Vilhelm & Akbari, Mansour, 2019, In : Nucleic Acids Research. 47, 8, p. 4086–4110Research output: Contribution to journal › Journal article › Research › peer-review
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Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy
Zheng, Jin, Akbari, Mansour, Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In : Acta Neuropathologica Communications. 8, 1, 23 p., 25.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1
Yang, J., Tadokoro, T., Keijzers, G., Mattson, M. P. & Bohr, Vilhelm, 2010, In : Journal of Biological Chemistry. 285, 36, p. 28191-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress
Yang, B., Figueroa, D. M., Hou, Y., Babbar, M., Baringer, S. L., Croteau, D. L. & Bohr, Vilhelm, 2019, In : Free Radical Biology and Medicine. 141, p. 47-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sarcopenia, Aging and Prospective Interventional Strategies
Waltz, T. B., Fivenson, E. M., Morevati, M., Li, C., Becker, K. G., Bohr, Vilhelm & Fang, E. F., 2018, In : Current Medicinal Chemistry. 25, 40, p. 5588-5596 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Modulation of DNA base excision repair during neuronal differentiation
Sykora, P., Yang, J., Ferrarelli, L. K., Tian, J., Tadokoro, T., Kulkarni, A., Weissman, L., Keijzers, G., Wilson, D. M., Mattson, M. P. & Bohr, Vilhelm, Jul 2013, In : Neurobiology of Aging. 34, 7, p. 1717-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aprataxin localizes to mitochondria and preserves mitochondrial function
Sykora, P., Croteau, D. L., Bohr, Vilhelm & Wilson, D. M., 3 May 2011, In : Proceedings of the National Academy of Sciences USA (PNAS). 108, 18, p. 7437-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA polymerase beta participates in mitochondrial DNA repair
Sykora, P., Kanno, S., Akbari, Mansour, Kulikowicz, T., Baptiste, B. A., Leandro, G. S., Lu, H., Tian, J., May, A., Becker, K. A., Croteau, D. L., Wilson, D. M., Sobol, R. W., Yasui, A. & Bohr, Vilhelm, Aug 2017, In : Molecular and Cellular Biology. 37, 16, e00237-17.Research output: Contribution to journal › Journal article › Research › peer-review
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Human RecQL4 helicase plays critical roles in prostate carcinogenesis
Su, Y., Meador, J. A., Calaf, G. M., Proietti De-Santis, L., Zhao, Y., Bohr, Vilhelm & Balajee, A. S., 15 Nov 2010, In : Cancer Research. 70, 22, p. 9207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human RECQL5beta stimulates flap endonuclease 1
Speina, E., Dawut, L., Hedayati, M., Wang, Z., May, A., Schwendener, S., Janscak, P., Croteau, D. L. & Bohr, Vilhelm, 1 May 2010, In : Nucleic Acids Symposium Series. 38, 9, p. 2904-16 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
Soerensen, M., Dato, S., Christensen, K., McGue, M., Stevnsner, T. V., Bohr, Vilhelm & Christiansen, L., 1 Dec 2010, In : Aging Cell. 9, 6, p. 1010-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The involvement of human RECQL4 in DNA double-strand break repair
Singh, D. K., Karmakar, P., Aamann, M. D., Schurman, S. H., May, A., Croteau, D. L., Burks, L., Plon, S. E. & Bohr, Vilhelm, 1 Jun 2010, In : Aging Cell. 9, 3, p. 358-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RECQ HELICASE RECQL4 PARTICIPATES IN NON-HOMOLOGOUS END JOINING AND INTERACTS WITH THE KU COMPLEX
Shamanna, R. A., Singh, D. K., Lu, H., Mirey, G., Keijzers, G., Salles, B., Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In : Carcinogenesis. 35, 11, p. 2415-2424 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protecting the mitochondrial powerhouse
Scheibye-Knudsen, Morten, Fang, E. F., Croteau, D. L., Wilson, D. M. & Bohr, Vilhelm, 1 Mar 2015, In : Trends in Cell Biology. 25, 3, p. 158-170 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
Scheibye-Knudsen, M., Ramamoorthy, M., Sykora, P., Maynard, S., Lin, P., Minor, R. K., Wilson, D. M., Cooper, M., Spencer, R., de Cabo, R., Croteau, D. L. & Bohr, Vilhelm, Apr 2012, In : The Journal of Experimental Medicine. 209, 4, p. 855-69 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
Scheibye-Knudsen, Morten, Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. ,. I., Brosh, R. M. ,. J., Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In : National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507Research output: Contribution to journal › Journal article › Research › peer-review
Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders
Scheibye-Knudsen, Morten, Fang, E. F., Croteau, D. L. & Bohr, Vilhelm, 2014, In : Autophagy. 10, 8, p. 1468-1469 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome
Scheibye-Knudsen, Morten, Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, Linda Hildegard, Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L., De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In : Cell Metabolism. 20, 5, p. 840-855 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Roles of Werner syndrome protein in protection of genome integrity
Rossi, M. L., Ghosh, A. K. & Bohr, Vilhelm, 2 Mar 2010, In : DNA Repair. 9, 3, p. 331-44 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding
Rossi, M. L., Ghosh, A. K., Kulikowicz, T., Croteau, D. L. & Bohr, Vilhelm, 1 Jul 2010, In : DNA Repair. 9, 7, p. 796-804 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1
Rhee, D. B., Ghosh, A., Lu, J., Bohr, Vilhelm & Liu, Y., 2 Jan 2011, In : DNA Repair. 10, 1, p. 34-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population
Rasmussen, Lene Juel, Shiloh, Y., Bergersen, Linda Hildegard, Sander, M., Bohr, Vilhelm & Tønjum, T., Oct 2013, In : Mechanisms of Ageing and Development. 134, 10, p. 427-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In : Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4975983
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511
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RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
175
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Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Research output: Contribution to journal › Journal article › Research › peer-review
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168
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Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Research output: Contribution to journal › Journal article › Research › peer-review
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