Vibe Hallundbæk Østergaard

Vibe Hallundbæk Østergaard

Associate Professor


  1. 2024
  2. Published

    A mutational atlas for Parkin proteostasis

    Clausen, L., Voutsinos, Vasileios, Cagiada, Matteo, Johansson, Kristoffer Enøe, Grønbæk-Thygesen, Martin, Nariya, S., Powell, R. L., Have, M. K. N., Østergaard, Vibe Hallundbæk, Stein, Amelie, Fowler, D. M., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Nature Communications. 15, 1, 17 p., 1541.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Emerging roles of the CIP2A–TopBP1 complex in genome integrity

    Ummethum, Henning Ole, Li, Jiayi, Lisby, Michael & Østergaard, Vibe Hallundbæk, 2023, In: NAR Cancer. 5, 4, 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2021
  6. Published

    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

    Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Functions of TopBP1 in preserving genome integrity during mitosis

    Bagge, J., Østergaard, Vibe Hallundbæk & Lisby, Michael, 2021, In: Seminars in Cell and Developmental Biology. 113, p. 57-64 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Large Intronic Deletion of the Fragile Site Gene PRKN Dramatically Lowers Its Fragility Without Impacting Gene Expression

    Munk, S. H. N., Voutsinos, Vasileios & Østergaard, Vibe Hallundbæk, 2021, In: Frontiers in Genetics. 12, 9 p., 695172.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2020
  10. Published

    A distinct role for recombination repair factors in an early cellular response to transcription-replication conflicts

    Shao, Xin, Joergensen, A. M., Howlett, N. G., Lisby, Michael & Østergaard, Vibe Hallundbæk, 2020, In: Nucleic Acids Research. 48, 10, p. 5467-5484 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

    Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2018
  13. Published

    Common Chromosomal Fragile Sites - Conserved Failure Stories

    Voutsinos, Vasileios, Munk, S. H. N. & Østergaard, Vibe Hallundbæk, 2018, In: Genes. 9, 12, p. 1-16 580.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells

    Pentzold, C., Shah, S. A., Hansen, Niels Richard, Le Tallec, B., Seguin-Orlando, A., Debatisse, M., Lisby, Michael & Østergaard, Vibe Hallundbæk, 2018, In: Nucleic Acids Research. 46, 3, p. 1280-1294 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    Transcription-replication conflicts at chromosomal fragile sites—consequences in M phase and beyond

    Østergaard, Vibe Hallundbæk & Lisby, Michael, Mar 2017, In: Chromosoma. 126, 2, p. 213-222 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. 2016
  18. Published

    The role of HERC2 and RNF8 ubiquitin E3 ligases in the promotion of translesion DNA synthesis in the chicken DT40 cell line

    Mohiuddin, M., Kobayashi, S., Keka, I. S., Guilbaud, G., Sale, J., Narita, Takeo, Abdel-Aziz, H. I., Wang, X., Ogawa, S., Sasanuma, H., Chiu, R., Østergaard, Vibe Hallundbæk, Lisby, Michael & Takeda, S., Apr 2016, In: DNA Repair. 40, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

    Moudry, P., Watanabe, K., Wolanin, K. M., Bartkova, J., Wassing, I. E., Watanabe, S., Strauss, R., Pedersen, R. T., Østergaard, Vibe Hallundbæk, Lisby, Michael, Andújar-Sánchez, M., Maya-Mendoza, A., Esashi, F., Lukas, Jiri & Bartek, J., 2016, In: The Journal of Cell Biology. 212, 3, p. 281-288 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    TopBP1 makes the final call for repair on the verge of cell division

    Østergaard, Vibe Hallundbæk & Lisby, Michael, 2016, In: Molecular & Cellular Oncology. 3, 2, 3 p., e1093066.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    TopBP1-mediated DNA processing during mitosis

    Gallina, I., Christiansen, S. K., Pedersen, R. T., Lisby, Michael & Østergaard, Vibe Hallundbæk, 2016, In: Cell Cycle. 15, 2, p. 176-183 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2015
  23. Published

    TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

    Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Published

    The genetic and biochemical basis of FANCD2 Monoubiquitination

    Rajendra, E., Østergaard, Vibe Hallundbæk, Langevin, F., Wang, M., Dornan, G. L., Patel, K. J. & Passmore, L. A., 2014, In: Molecular Cell. 54, 5, p. 858-869 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability

    Germann, S. M., Schramke, V., Pedersen, R. T., Gallina, I., Eckert-Boulet, N., Østergaard, Vibe Hallundbæk & Lisby, Michael, 2014, In: Journal of Cell Biology. 204, 1, p. 45-59 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2012
  28. Published

    RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

    Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In: D N A Repair. 11, 11, p. 892–905 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2011
  30. Published

    Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination

    Germann, S. M., Østergaard, Vibe Hallundbæk, Haas, C., Salis, P., Motegi, A. & Lisby, Michael, 2011, In: D N A Repair. 10, 2, p. 210-224 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2009
  32. The QTK Loop is Essential for the Communication between the N-Terminal ATPase Domain and the Central Cleavage-Ligation Region in Human Topoisomerase IIα

    Bendsen, S., Østergaard, Vibe Hallundbæk, Skouboe, C., Brinch, M., Knudsen, B. R. & Andersen, A. H., 2009, In: Biochemistry. 48, 27, p. 6508-6515 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2007
  34. Published

    Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair

    Østergaard, Vibe Hallundbæk, Langevin, F., Kuiken, H. J., Pace, P., Niedzwiedz, W., Simpson, L. J., Ohzeki, M., Takata, M., Sale, J. E. & Patel, K. J., 14 Dec 2007, In: Molecular Cell. 28, 5, p. 798-809 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2006
  36. Published

    RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40

    Simpson, L. J., Ross, A. L., Szüts, D., Alviani, C. A., Østergaard, Vibe Hallundbæk, Patel, K. J. & Sale, J. E., 1 Sep 2006, In: EMBO Reports. 7, 9, p. 927-932 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2004
  38. Published

    Dissecting the cell-killing mechanism of the topoisomerase II-targeting drug ICRF-193

    Østergaard, Vibe Hallundbæk, Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28100-28105 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Hindering the strand passage reaction of human topoisomerase IIα without disturbing DNA cleavage, ATP hydrolysis, or the operation of the N-terminal clamp

    Østergaard, Vibe Hallundbæk, Giangiacomo, L., Bjergbaek, L., Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28093-28099 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The Transducer Domain Is Important for Clamp Operation in Human DNA Topoisomerase IIα

    Østergaard, Vibe Hallundbæk, Bjergbaek, L., Skouboe, C., Giangiacomo, L., Knudsen, B. R. & Andersen, A. H., 16 Jan 2004, In: Journal of Biological Chemistry. 279, 3, p. 1684-1691 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2003
  42. Published

    A human topoisomerase IIα heterodimer with only one ATP binding site can go through successive catalytic cycles

    Skouboe, C., Bjergbaek, L., Østergaard, Vibe Hallundbæk, Larsen, M. K., Knudsen, B. R. & Andersen, A. H., 21 Feb 2003, In: Journal of Biological Chemistry. 278, 8, p. 5768-5774 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11903628