Ulrik Gether

Ulrik Gether

Head of Department, Professor


  1. 2003
  2. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In : European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy

    Rasmussen, Søren Gøgsig Faarup, Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, Ulrik, 31 Oct 2003, In : European Journal of Pharmacology. 479, 1-3, p. 13-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter

    Norregaard, L., Loland, Claus Juul & Gether, Ulrik, 15 Aug 2003, In : The Journal of Biological Chemistry. 278, 33, p. 30587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 14 Feb 2003, In : The Journal of Biological Chemistry. 278, 7, p. 4990-5000 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Evidence for distinct sodium-, dopamine-, cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine

    Norregaard, L., Loland, Claus Juul & Gether, Ulrik, 2003, In : Journal of Biological Chemistry. Vol. 278 (33), p. 30587-96

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter interanalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 2003, In : Journal of Biological Chemistry. Vol. 278 (7), p. 4990-5000

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Probing dopamine transporter structure and function y Zn2+ site engineering

    Loland, Claus Juul, Nørgaard-Nielsen, K. & Gether, Ulrik, 2003, In : European Journal of Pharmacology. Vol. 479, no 1-3, p. 187-97

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Residues in the extracellular loop 4 are critical for maintaining the conformational equilibrium of the gamma-aminobutyric acid transporter-1.

    MacAulay, Nanna, Meinild, A., Zeuthen, T. & Gether, Ulrik, 2003, In : Journal of Biological Chemistry. 278, 31, p. 28771-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2002
  11. Published

    Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1

    MacAulay, Nanna, Zeuthen, T. & Gether, Ulrik, 15 Oct 2002, In : Journal of Physiology. 544, Pt 2, p. 447-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Zn(2+) site engineering at the oligomeric interface of the dopamine transporter

    Norgaard-Nielsen, K., Norregaard, L., Hastrup, H., Javitch, J. A. & Gether, Ulrik, 31 Jul 2002, In : FEBS letters. 524, 1-3, p. 87-91 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The role of zinc ions in reverse transport mediated by monoamine transporters

    Scholze, P., Nørregaard, L., Singer, E. A., Freissmuth, M., Gether, Ulrik & Sitte, H. H., 14 Jun 2002, In : Journal of Biological Chemistry. 277, 24, p. 21505-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Conformational basis for the Li+- induced leak current in the rat ¿- aminobutyric acid (GABA) transporter- 1

    MacAulay, Nanna, Zeuthen, T. & Gether, Ulrik, 2002, In : Journal of Physiology. 544, 2, p. 447-458

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In : Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Passive water and urea permeability of a human Na(+)-glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klærke, Dan Arne & Zeuthen, T., 2002, In : Journal of Physiology. 542, 3, p. 817-828 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Structural basis for activation of G-protein-coupled receptors.

    Gether, Ulrik, Asmar, F., Meinild, A. K. & Rasmussen, Søren Gøgsig Faarup, 2002, In : Basic & Clinical Pharmacology & Toxicology. 91, 6, p. 304-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The role of zine ions in reverse transport mediated by monoamine transporters

    Scholze, P., Norregaard, L., Singer, E. A., Freissmuth, M., Gether, Ulrik & Sitte, H. H., 2002, In : Journal of Biological Chemistry. 277, p. 21505-21513

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Understanding G-protein coupled receptors and their role in the CNS

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2002, Structural mechanics of GPCR activation. p. 43-62

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  21. Published

    Use of fluorescence spectroscopy to study conformational changes in the beta 2-adrenoceptor

    Kobilka, B. K. & Gether, Ulrik, 2002, In : Methods in Enzymology. 343, 343, p. 170-182 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Zn(2+) site engineering oat the oligomeric interface of the dopamine transporter

    Nørgaard-Nielsen, K., Norregaard, L., Hastrup-Nielsen, H., Javitch, J. A. & Gether, Ulrik, 2002, In : FEBS Letters. vol. 524(1-3), p. 87-91

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2001
  24. Published

    Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6

    Ballesteros, J. A., Jensen, A. D., Liapakis, G., Rasmussen, Søren Gøgsig Faarup, Shi, L. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276 (31), p. 29171-29177

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling

    Jensen, A. D., Guarnieri, F., Rasmussen, Søren Gøgsig Faarup, Asmar, F., Ballesteros, J. A. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276 (12), p. 9279-9290

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

    Rasmussen, Søren Gøgsig Faarup, Carroll, F. I., Maresch, M. J., Jensen, A. D. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276 (7), p. 4717-4723

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites

    Gether, Ulrik, Norregaard, L. & Loland, Claus Juul, 2001, In : Life Sciences. 68 (19-20), p. 2187-2198

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Engineered Zn(2+)switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents

    MacAulay, Nanna, Bendahan, A., Loland, Claus Juul, Zeuthen, T., Kanner, B. I. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276, p. 40476-40485

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations

    Seifert, R., Wenzel-Seifert, K., Gether, Ulrik & Kobilka, B. K., 2001, In : Journal of Pharmacology and Experimental Therapeutics. 297 (3), p. 1218-1226

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J. A., Weinstein, H. & Gether, Ulrik, 2001, In : Biochemistry. 39 (51), p. 15836-15846

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Water transport by the human Na+-coupled glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klaerke, D. A. & Zeuthen, T., 2001, In : Journal of Physiology. 530 (Pt 3), p. 367-378

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2000
  33. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J., Weinstein, H. & Gether, Ulrik, 26 Dec 2000, In : Biochemistry. 39, 51, p. 15836-15846 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Assessing adrenergic receptor conformation using chemically reactive fluorescent probes

    Jensen Dam, A. & Gether, Ulrik, 2000, Methods in Molecular Biology, vol.126: Adrenergic Receptors Protocols. Totowa, NJ: Humana Press, p. 345-359

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  35. Published

    The effect of pH on ß2 adrenoceptor function

    Pejman, G., Hans, S., Roland, S., Tae Weon, L., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik & Kobilka, B. K., 2000, In : Journal of Biological Chemistry. 5, Vol. 275, p. 3121-3127

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Uncovering molecular mechanism involved in activation of G protein-coupled receptors

    Gether, Ulrik, 2000, In : Endocrine Reviews. 21(1), p. 90-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 1999
  38. Published

    Assessing adrenergic receptor using chemically reactive fluorescent probes

    Dam Jensen, A. & Gether, Ulrik, 1999, In Adrenergic Receptor Protocols, in the Methods for Molecular Biology. Humana Press, p. 345-361

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  39. Published

    Characterization of ligand-induced conformational states in the beta 2 adrenergic receptor

    Kobilka, B. K., Gether, Ulrik, Seifert, R., Lin, S. & Ghanouni, P., 1999, In : Journal of Receptors and Signal Transduction. 19, p. 293-300

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

    Loland, Claus Juul, Norregaard, L. & Gether, Ulrik, 1999, In : Journal of Biological Chemistry. 274, 52, p. 36928-34 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Direct assessment of conformational changes in G protein coupled receptors using fluorescence spectroscopy

    Gether, Ulrik & Kobilka, B. K., 1999, In Signal Transduction - A practical Approach, in The practical Approach series, 2nd edition. Oxford: Oxford University Press, p. 01-17

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  42. Published

    Effects of guanine, inosine, and xanthine nucleotides on beta(2)-adrenergic receptor/G(s) interactions: evidence for multiple receptor conformations

    Seifert, R., Gether, Ulrik, Wenzel-Seifert, K. & Kobilka, B. K., 1999, In : Molecular Pharmacology. 56, p. 348-358

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Examining the efficiency of receptor/G-protein coupling with a cleavable beta2-adrenoceptor-Gsalpha fusion protein

    Seifert, R., Wenzel-Seifert, K., Gether, Ulrik, Lam, V. T. & Kobilka, B. K., 1999, In : European Journal of Biochemistry. 260, p. 661-666

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Fluorescence spectrosocpy analysis of conformational changes in the Β2 adrenergic receptor

    Gether, Ulrik, 1999, In Structure/Function of G-protein coupled receptors, in the Receptor Biochemistry and Methodology. New York: Wiley, p. 315-334

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  45. Published

    Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI

    Rasmussen, Søren Gøgsig Faarup, Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, Ulrik, 1999, In : Molecular Pharmacology. 56, p. 175-184

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 1998
  47. Published

    Delineation of an endogenous zinc-binding site in the human dopamine transporter.

    Norregaard, L., Frederiksen, D., Nielsen, E. Ø. & Gether, Ulrik, 1998, In : EMBO Journal. 17, p. 4266-4273

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 1990
  49. Published

    Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

    Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & tml152, tml152, 1990, In : F E B S Letters. 260, 1, p. 73-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

    Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., tml152, tml152 & Schwartz, Thue W., 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 3 4 Next

ID: 11898