Ulrik Gether

Ulrik Gether

Head of Department, Professor


  1. 2009
  2. Published

    Do stressful life events predict medical treatment outcome in first episode of depression?

    Bock, C., Bukh, J. D., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. D., Vinberg, Maj, Gether, U. & Kessing, Lars Vedel, 2009, In : Social Psychiatry and Psychiatric Epidemiology. 44, 9, p. 752-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Does bereavement-related first episode depression differ from other kinds of first depressions?

    Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj & Gether, U., 2009, In : Social Psychiatry and Psychiatric Epidemiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Elucidating Conformational Changes in the {gamma}-Aminobutyric Acid Transporter-1

    Meinild, A., Loo, D. D. F., Hansen, S. S., Gether, Ulrik & MacAulay, Nanna, 2009, In : Journal of Biological Chemistry. 284, 24, p. 16226-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    How curved membranes recruit amphipathic helices and protein anchoring motifs

    Hatzakis, Nikos, Bhatia, V. K., Larsen, J., Madsen, Kenneth Lindegaard, Bolinger, P., Kunding, A. H., Castillo Leon, J. J., Gether, Ulrik, Hedegård, Per & Stamou, Dimitrios, 2009, In : Nature Chemical Biology. 5, 11, p. 835-841 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Interaction between genetic polymorphisms and stressful life events in first episode depression

    Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In : Journal of Affective Disorders. 119, 1-3, p. 107-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Introducing tetraCys motifs at two different sites results in a functional dopamine transporter

    Orun, O., Rasmussen, S. & Gether, Ulrik, 2009, In : Acta Biologica Hungarica. 60, 1, p. 15-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Neurotransmitter transporters: structure and function

    Loland, Claus Juul & Gether, Ulrik, 2009, Texbook of Drug Design and Discovery. Madsen, U., Krogsgaard-Larsen, P. & Stromgaard, K. (eds.). 4 ed. Taylor & Francis

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  9. Published

    No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment

    Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In : European Neuropsychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    PICK1 expression in the Drosophila central nervous system primarily occurs in the neuroendocrine system

    Jansen, A. M., Nässel, D. R., Madsen, Kenneth Lindegaard, Jung, A. G., Gether, Ulrik & Kjærulff, Ole, 2009, In : Journal of Comparative Neurology. 517, 3, p. 313-32 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    Validity of the diagnosis of a single depressive episode in a case register

    Bock, C., Bukh, J. D., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. D., Vinberg, Maj, Gether, U. & Kessing, Lars Vedel, 2009, In : Clinical Practice and Epidemiology in Mental Health. 5, p. 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs

    Eriksen, J., Rasmussen, Søren Gøgsig Faarup, Jørgensen, T. N., Vaegter, C. B., Cha, J. H., Zou, M., Newman, A. H. & Gether, Ulrik, 2009, In : Journal of Neuroscience. 29, 21, p. 6794-808 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2008
  15. Published

    An intracellular interaction network regulates conformational transitions in the dopamine transporter.

    Kniazeff, J., Shi, L., Loland, Claus Juul, Javitch, J. A., Weinstein, H. & Gether, Ulrik, 2008, In : Journal of Biological Chemistry. 283, 25, p. 17691-701 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Are life events prior to first episode of major depression a predictor of medical treatment outcome?

    Bock, C., Bukh, J. D., Christensen, M. V., Gether, Ulrik & Kessing, L. V., 2008, In : European Psychiatry. 23, Suppl. 2, p. S200-S200

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Correlation between genetic and geographic structure in Europe

    Lao, O., Lu, T. T., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A., Gether, Ulrik, Werge, Thomas, Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Gieger, C., Wichmann, H., Rüther, A., Schreiber, S., Becker, C., Nürnberg, P., Nelson, M. R., Krawczak, M. & Kayser, M., 2008, In : Current Biology. 18, 16, p. 1241-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genetic Polymorphisms and the outcome of antidepressant Treatment

    Bukh, J. D., Bock, C., Christensen, M. V., Gether, Ulrik & Kessing, L. V., 2008, In : European Psychiatry. 23, p. S200-S200

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glycine transporter dimers - Evidence for occurrence in the plasma membrane

    Bartholomaeus, I., Milan-Lobo, L., Nicke, A., Dutertre, S., Hastrup, H., Jha, A., Gether, Ulrik, Sitte, H. H., Betz, H. & Eulenburg, V., 2008, In : Journal of Biological Chemistry. 283, 16, p. 10978-10991 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glycine transporter dimers: evidence for occurrence in the plasma membrane

    Bartholomäus, I., Milan-Lobo, L., Nicke, A., Dutertre, S., Hastrup, H., Jha, A., Gether, Ulrik, Sitte, H. H., Betz, H. & Eulenburg, V., 2008, In : Journal of Biological Chemistry. 283, 16, p. 10978-91 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1

    Bassan, M., Liu, H., Madsen, Kenneth Lindegaard, Armsen, W., Zhou, J., Desilva, T., Chen, W., Paradise, A., Brasch, M. A., Staudinger, J., Gether, Ulrik, Irwin, N. & Rosenberg, P. A., 2008, In : European Journal of Neuroscience. 27, 1, p. 66-82 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Membrane localization is critical for activation of the PICK1 BAR domain

    Madsen, Kenneth Lindegaard, Eriksen, J., Milan-Lobo, L., Han, D. S., Niv, M. Y., Ammendrup-Johnsen, I., Henriksen, U., Bhatia, V. K., Stamou, Dimitrios, Sitte, H. H., McMahon, H. T., Weinstein, H. & Gether, Ulrik, 2008, In : Traffic - International Journal of Intracellular Transport. 9, 8, p. 1327-43 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Membrane localization is critical for activation of the PICK1BAR domain

    Madsen, K. L., Eriksen, J., Milan-Lobo, L., Han, D. S., Niv, M. Y., mmendrup-Johnsen, I., Henriksen, U., Bhatia, V. K., Stamou, Dimitrios, Sitte, H. H., McMahon, H. T., Weinstein, H. & Gether, Ulrik, 2008, In : Traffic - International Journal of Intracellular Transport. 9, 8, p. 1327-1343 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling

    Klewe, I. V., Nielsen, S. M., Tarpø, L., Urizar, E., Dipace, C., Javitch, J. A., Gether, Ulrik, Egebjerg, J. & Christensen, K. V., 2008, In : Neuropharmacology. 54, 8, p. 1215-1222 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Reliability of clinical ICD-10 diagnoses among electroconvulsive therapy patients with chronic affective disorders

    Jakobsen, K. D., Hansen, T. F., Dam, H., Larsen, E. B., Gether, Ulrik & Werge, Thomas, 2008, In : European Journal of Psychiatry. 22, 3, p. 161-172 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

    Binda, F., Dipace, C., Bowton, E., Robertson, S. D., Lute, B. J., Fog, J. U., Zhang, M., Sen, N., Colbran, R. J., Gnegy, M. E., Gether, Ulrik, Javitch, J. A., Erreger, K. & Galli, A., 2008, In : Molecular Pharmacology. 74, 4, p. 1101-1108 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The binding sites for cocaine and dopamine in the dopamine transporter overlap.

    Beuming, T., Kniazeff, J., Bergmann, M. L., Shi, L., Gracia, L., Raniszewska, K., Newman, A. H., Javitch, J. A., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 2008, In : Nature Neuroscience. 11, 7, p. 780-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2007
  29. Published

    Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites

    Plenge, P., Gether, Ulrik & Rasmussen, Søren Gøgsig Faarup, 2007, In : European Journal of Pharmacology. 567, 1-2, p. 1-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching

    Adkins, E. M., Samuvel, D. J., Fog, J. U., Eriksen, J., Jayanthi, L. D., Vaegter, C. B., Ramamoorthy, S. & Gether, Ulrik, 2007, In : Biochemistry. 46, 37, p. 10484-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

    Loland, Claus Juul, Desai, R. I., Zou, M., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L. & Gether, Ulrik, 2007, In : Molecular Pharmacology. 73, 3, p. 813-23 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2006
  33. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, Arne, Jul 2006, In : Trends in Pharmacological Sciences. 27, 7, p. 375-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport

    Fog, J. U., Khoshbouei, H., Holy, M., Owens, W. A., Vaegter, C. B., Sen, N., Nikandrova, Y., Bowton, E., McMahon, D. G., Colbran, R. J., Daws, L. C., Sitte, H. H., Javitch, J. A., Galli, A. & Gether, Ulrik, 2006, In : Neuron. 51, 4, p. 417-429 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype

    Martinat, C., Bacci, J., Leete, T., Kim, J., Vanti, W. B., Newman, A. H., Cha, J. H., Gether, Ulrik, Wang, H. & Abeliovich, A., 2006, In : Proceedings of the National Academy of Science of the United States of America. 103, 8, p. 2874-2879 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding (vol 279, pg 3228, 2004)

    Loland, C. J., Granas, C., Javitch, J. A. & Gether, Ulrik, 2006, In : Journal of Biological Chemistry. 281, 35, p. 25867-25867

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Molecular mechanisms of GPCR activation

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2006, G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive ActivityG Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity. 2006: Wiley, Vol. 24. p. 27-42 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  38. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, A., 2006, In : Trends in Pharmacological Sciences. 27, 7, p. 375-383 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization

    Jayanthi, L. D., Annamalai, B., Samuvel, D. J., Gether, Ulrik & Ramamoorthy, S., 2006, In : Journal of Biological Chemistry. 281, 33, p. 23326-40 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Regulation of dopamine transporter trafficking by intracellular amphetamine.

    Kahlig, K. M., Lute, B. J., Wei, Y., Loland, Claus Juul, Gether, Ulrik, Javitch, J. A. & Galli, A., 2006, In : Molecular Pharmacology. 70, 2, p. 542-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Zn2+ modulation of neurotransmitter transporters

    Nørgaard-Nielsen, K. & Gether, Ulrik, 2006, In : Handbook of Experimental Pharmacology. 175, p. 1-22 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2005
  43. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In : Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2

    Henriksen, U. B., Fog, J. U., Litman, Thomas & Gether, Ulrik, 4 Nov 2005, In : Journal of Biological Chemistry. 280, 44, p. 36926-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8

    Kniazeff, J., Loland, Claus Juul, Goldberg, N., Quick, M., Das, S., Sitte, H. H., Javitch, J. A. & Gether, Ulrik, Nov 2005, In : Neuropharmacology. 49, 6, p. 715-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2

    Henriksen, U. B., Gether, Ulrik & Litman, Thomas, 1 Apr 2005, In : Journal of Cell Science. 118, Pt 7, p. 1417-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Purification and fluorescent labeling of the human serotonin transporter

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 8 Mar 2005, In : Biochemistry. 44, 9, p. 3494-505 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Molecular determinants for the complex binding specificity of the PDZ domain in PICK1

    Madsen, Kenneth Lindegaard, Beuming, T., Niv, M. Y., Chang, C., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In : Journal of Biological Chemistry. 280, 21, p. 20539-48 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Molecular determinants for the complex binding specifity of the PDZ domain in PICK1

    Madsen, K. L., Beuming, T., Niv, M. Y., Chang, C. W., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In : Journal of Biological Chemistry. Vol. 280, no. 21, p. 20539-48

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2004
  51. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding

    Loland, Claus Juul, Grånäs, C., Javitch, J. A. & Gether, Ulrik, 30 Jan 2004, In : The Journal of Biological Chemistry. 279, 5, p. 3228-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Insights from endogenous and engineered Zn2+-binding sites in monoanine transporters

    Loland, Claus Juul & Gether, Ulrik, 2004, Molecular Neuropharmacology: Strategies and Methods. p. 191-213

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  53. Published

    Intracellular residues in the dopamine transporter critical for conformational isomerization, molecular gating and cocaine binding

    Loland, Claus Juul, Granas, C., Javitc, J. & Gether, Ulrik, 2004, In : Journal of Biological Chemistry. Vol. 279, no. 5, p. 3228-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ doamin interactions

    Bjerggaard, C., Fog, J. U., Hastrup-Nielsen, H., Madsen, K., Loland, Claus Juul, Javitch, J. & Gether, Ulrik, 2004, In : Journal of Neuroscience. Vol. 24, no. 31, p. 7024-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions

    Bjerggaard, C., Fog, J. U., Hastrup, H., Madsen, Kenneth Lindegaard, Loland, C. J., Javitch, J. A. & Gether, Ulrik, 2004, In : Journal of Neuroscience. 24, 31, p. 7024-36 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Zinc Potentiates an Uncoupled Anion Conductance Associated with the Dopamine Transporter

    Meinild, A., Sitte, H. H. & Gether, Ulrik, 2004, In : Journal of Biological Chemistry. 279, 48, p. 49671-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11898