Ulla M. Wewer
Professor
BRIC Administration
Ole Maaløes Vej 5
2200 København N.
- 2018
- Published
Personlig medicin vil involvere alle specialer, og det handler om andet end genomet
Ullum, H., Hersom, C., Wewer, Ulla M., Skøtt, O., Nielsen, L. B. & Rasmussen, L. H., 2018, In: Ugeskrift for Laeger. 180, 6, p. 501 1 p.Research output: Contribution to journal › Editorial › Research
- 2017
- Published
Corporate culture: research can benefit
Westendorp, Rudi GJ & Wewer, Ulla M., 2017, In: Nature. 542, 7641, 1 p., 295.Research output: Contribution to journal › Journal article › Communication
- 2016
- Published
The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
Høye, A. M., Couchman, John Robert, Wewer, Ulla M. & Yoneda, A., 2016, In: Scientific Reports. 6, 14 p., 28529.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth
Albrechtsen, Reidar, Kveiborg, Marie, Hansen, D. S., Vikeså, J., Noer, Julie Boertmann, Kotzsh, A., Nielsen, Finn Cilius, Wewer, Ulla M. & Frohlich, C., 15 Oct 2013, In: Journal of Cell Science. 126, 20, p. 4707-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12
Kveiborg, Marie, Fröhlich, C., Albrechtsen, Reidar & Wewer, Ulla M., 29 Aug 2013, Handbook of Proteolytic Enzymes. Elsevier, Vol. 1. p. 1114-1122 9 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins
Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In: Biochemical Journal. 452, 1, p. 97-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of ROCK Activity in Cancer
Morgan-Fisher, M., Wewer, Ulla M. & Yoneda, A., 29 Jan 2013, In: Journal of Histochemistry and Cytochemistry. 61, 3, p. 185-198Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The newcomer in the integrin family: Integrin α9 in biology and cancer.
Høye, A. M., Couchman, John Robert, Wewer, Ulla M., Yoneda, A. & Fukami, K., May 2012, In: Advances in Biological Regulation. 52, 2, p. 326-339Research output: Contribution to journal › Review › Research › peer-review
- Published
A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II
Yoneda, A., Morgan-Fisher, M., Wait, R., Couchman, John Robert & Wewer, Ulla M., 2012, In: Molecular and Cellular Biology. 32, 10, p. 1788-804 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanism
Hansen, D. S., Leyme, A., Grandal, M. V., Albrechtsen, Reidar, van Deurs, B., Wewer, Ulla M. & Kveiborg, Marie, 2012, In: Traffic - International Journal of Intracellular Transport. 13, 11, p. 1532-46 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Analysis of a Breast Cancer-Associated Mutation in the Intracellular Domain of the Metalloprotease ADAM12
Stautz, D., Wewer, Ulla M. & Kveiborg, Marie, 2012, In: P L o S One. 7, 5, p. e37628Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression
Frohlich, C., Nehammer, C., Albrechtsen, Reidar, Kronqvist, P., Kveiborg, Marie, Sehara-Fujisawa, A., Mercurio, A. M. & Wewer, Ulla M., 29 Aug 2011, In: Molecular Cancer Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KU bestemmer selv over sin forskning
Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication
- Published
Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity
Albrechtsen, Reidar, Hansen, D. S., Sanjay, A., Kveiborg, Marie & Wewer, Ulla M., 15 Jan 2011, In: Experimental Cell Research. 317, 2, p. 195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity
Stautz, D., Sanjay, A., Hansen, M. T., Albrechtsen, Reidar, Wewer, Ulla M. & Kveiborg, Marie, 2010, In: Experimental Cell Research. 316, 1, p. 55-67Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2)
Kveiborg, Marie, Jacobsen, J., Lee, M., Nagase, H., Wewer, Ulla M. & Murphy, G., 2010, In: Biochemical Journal. 430, 1, p. 79-86 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage
Lydolph, M. C., Morgan-Fisher, M., Høye, A. M., Couchman, John Robert, Wewer, Ulla M. & Yoneda, A., 2009, In: Experimental Cell Research. 315, 19, p. 3312-24 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired cutaneous wound healing in mice lacking tetranectin
Iba, K., Hatakeyama, N., Kojima, T., Murata, M., Matsumura, T., Wewer, Ulla M., Wada, T., Sawada, N. & Yamashita, T., 2009, In: Wound Repair and Regeneration. 17, 1, p. 108-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting ADAM12 in human disease: head, body or tail?
Jacobsen, J. & Wewer, Ulla M., 2009, In: Current Pharmaceutical Design. 15, 20, p. 2300-10 10 p.Research output: Contribution to journal › Review › Research
- 2008
- Published
ADAM12: a potential target for the treatment of chronic wounds
Harsha, A., Stojadinovic, O., Brem, H., Sehara-Fujisawa, A., Wewer, Ulla M., Loomis, C. A., Blobel, C. P. & Tomic-Canic, M., 1 Aug 2008, In: Journal of Molecular Medicine. 86, 8, p. 961-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment
Pories, S. E., Zurakowski, D., Roy, R., Lamb, C. C., Raza, S., Exarhopoulos, A., Scheib, R. G., Schumer, S., Lenahan, C., Borges, V., Louis, G. W., Anand, A., Isakovich, N., Hirshfield-Bartek, J., Wewer, Ulla M., Lotz, M. M. & Moses, M. A., 1 May 2008, In: Cancer Epidemiology, Biomarkers & Prevention. 17, 5, p. 1034-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging-From molecules to populations.
Sander, M., Avlund, K., Lauritzen, Martin, Gottlieb, T., Stevnsner, T., Wewer, Ulla M. & Bohr, V. A., 2008, In: Mechanisms of Ageing and Development. 129, p. 614-623Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Catalytic properties of ADAM12 and its domain deletion mutants.
Jacobsen, J., Visse, R., Sørensen, H. P., Enghild, J. J., Brew, K., Wewer, Ulla M. & Nagase, H., 2008, In: Biochemistry. 47, 2, p. 537-547 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular roles of ADAM12 in health and disease.
Kveiborg, Marie, Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2008, In: International Journal of Biochemistry & Cell Biology. 40, 9, p. 1685-702 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression, purification and insights into structure and folding of the ADAM22 pro domain.
Sørensen, H. P., Jacobsen, J., Nielbo, S., Poulsen, F. M. & Wewer, Ulla M., 2008, In: Protein Expression and Purification. 61, 2, p. 175-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heparan sulfate regulates ADAM12 through a molecular switch mechanism.
Sørensen, H. P., Vives, R. R., Manetopoulos, C., Albrechtsen, Reidar, Lydolph, M. C., Jacobsen, J., Couchman, John Robert & Wewer, Ulla M., 2008, In: Journal of Biological Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice
Jørgensen, L. H., Jensen, C. H., Wewer, Ulla M. & Schrøder, H. D., 1 Nov 2007, In: American Journal of Pathology. 171, 5, p. 1599-607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome
Christiansen, M., Spencer, K., Laigaard, J., Cowans, N. J., Larsen, S. O. & Wewer, Ulla M., 2007, In: Prenatal Diagnosis. 27, 7, p. 611-615 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forsknings- og ytringsfriheden på universiteterne: forskningspolitisk årsmøde 2007
Kærgård, Niels, Bache, C., Flensted-Jensen, M., Harder, Peter, Olesen, Søren-Peter & Wewer, Ulla M., 2007, København: Det Kongelige Danske Videnskabernes Selskab.Research output: Book/Report › Book › Communication
- Published
The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor
Atfi, A., Dumont, E., Colland, F., Bonnier, D., L'helgoualc'h, A., Prunier, C., Ferrand, N., Clément, B., Wewer, Ulla M. & Théret, N., 2007, In: Journal of Cell Biology. 178, 2, p. 201-208 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome
Laigaard, J., Spencer, K., Christiansen, M., Cowans, N. J., Larsen, S. O., Pedersen, B. N. & Wewer, Ulla M., 2006, In: Prenatal Diagnosis. 26, 10, p. 973-979 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme.
Wewer, Ulla M., Mörgelin, M., Holck, P., Jacobsen, J., Lydolph, M. C., Johnsen, A. H., Kveiborg, Marie & Albrechtsen, Reidar, 2006, In: Journal of Biological Chemistry. 281, 14, p. 9418-22 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12-S stimulates bone growth in transgenic mice by modulating chondrocyte proliferation and maturation.
Kveiborg, Marie, Albrechtsen, Reidar, Rudkjaer, L., Wen, G., Damgaard-Pedersen, K. & Wewer, Ulla M., 2006, In: Journal of Bone and Mineral Research. 21, 8, p. 1288-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal serum ADAM12 levels in Down and Edwards' syndrome pregnancies at 9-12 weeks' gestation
Laigaard, J., Cuckle, H., Wewer, Ulla M. & Christiansen, M., 2006, In: Prenatal Diagnosis. 26, 8, p. 689-691 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular profiling of ADAM12 in human bladder cancer.
Albrechtsen, Reidar, Dyrskjøt, L., Rudkjaer, L., Ørntoft, T. F., Frohlich, C. & Wewer, Ulla M., 2006, In: Clinical Cancer Research. 12, 24, p. 7359-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA-binding IMPs promote cell adhesion and invadopodia formation.
Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells
Le Pabic, H., L'Helgoualc'h, A., Coutant, A., Wewer, Ulla M., Baffet, G., Clément, B. & Théret, N., 1 Dec 2005, In: Journal of Hepatology. 43, 6, p. 1038-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sub-cellular localisation of fukutin related protein in different cell lines and in the muscle of patients with MDC1C and LGMD2I
Torelli, S., Brown, S. C., Brockington, M., Dolatshad, N. F., Jimenez, C., Skordis, L., Feng, L. H., Merlini, L., Jones, D. H., Romero, N., Wewer, Ulla M., Voit, T., Sewry, C. A., Noguchi, S., Nishino, I. & Muntoni, F., 1 Dec 2005, In: Neuromuscular Disorders. 15, 12, p. 836-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 overexpression does not improve outcome in mice with laminin alpha2-deficient muscular dystrophy
Guo, L. T., Shelton, G. D., Wewer, Ulla M. & Engvall, E., 1 Nov 2005, In: Neuromuscular Disorders. 15, 11, p. 786-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage
Li, S., Bordoy, R., Stanchi, F., Moser, M., Braun, A., Kudlacek, O., Wewer, Ulla M., Yurchenco, P. D. & Fässler, R., 1 Jul 2005, In: Journal of Cell Science. 118, Pt 13, p. 2913-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 and alpha9beta1 integrin are instrumental in human myogenic cell differentiation
Lafuste, P., Sonnet, C., Chazaud, B., Dreyfus, P. A., Gherardi, R. K., Wewer, Ulla M. & Authier, F., 1 Feb 2005, In: Molecular Biology of the Cell. 16, 2, p. 861-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role for ADAM12 in breast tumor progression and stromal cell apoptosis.
Kveiborg, Marie, Frohlich, C., Albrechtsen, Reidar, Tischler, V., Dietrich, N., Holck, P., Kronqvist, P., Rank, F., Mercurio, A. M. & Wewer, Ulla M., 2005, In: Cancer Research. 65, 11, p. 4754-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
Thodeti, C. K., Frohlich, C., Nielsen, C. K., Takada, Y., Fässler, R., Albrechtsen, Reidar & Wewer, Ulla M., 2005, In: FEBS Letters. 579, 25, p. 5589-95 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer
Hammer, N. A., Hansen, Thomas van Overeem, Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2005, In: Reproduction. 130, 2, p. 203-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchy of ADAM12 binding to integrins in tumor cells.
Thodeti, C. K., Fröhlich, C., Nielsen, C. K., Holck, P., Sundberg, C., Kveiborg, Marie, Mahalingam, Y., Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2005, In: Experimental Cell Research. 309, 2, p. 438-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of the disintegrin and metalloprotease ADAM12 in preeclampsia.
Laigaard, J., Sørensen, T., Placing, S., Holck, P., Frohlich, C., Wøjdemann, K. R., Sundberg, K., Shalmi, A., Tabor, A., Nørgaard-Pedersen, B., Ottesen, B., Christiansen, M. & Wewer, Ulla M., 2005, In: Obstetrics and Gynecology. 106, 1, p. 144-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18.
Laigaard, J., Christiansen, M., Frohlich, C., Pedersen, B. N., Ottesen, B. & Wewer, Ulla M., 2005, In: Prenatal Diagnosis. 25, 1, p. 45-6 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage
Roy, R., Wewer, Ulla M., Zurakowski, D., Pories, S. E. & Moses, M. A., 3 Dec 2004, In: Journal of Biological Chemistry. 279, 49, p. 51323-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice
Hansen, Thomas van Overeem, Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 914939
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The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
Research output: Contribution to journal › Journal article › Research › peer-review
Published