Uffe Kristiansen

Uffe Kristiansen

Associate Professor


  1. 2024
  2. Published

    Long-term immune cell profiling in stroke patients with or without infections

    Sørensen, N. V., Hasseldam, Henrik, Johansen, F. F., Kristiansen, Uffe, Overgaard, K., Iversen, Helle Klingenberg & Rasmussen, Rune Skovgaard, 2024, In: International Journal of Neuroscience. 134, 2, p. 197-205

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2021
  4. Published

    An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion

    Jørgensen, Anders, Thygesen, M. B., Kristiansen, Uffe & Poulsen, Henrik Enghusen, 2021, In: Scandinavian Journal of Clinical and Laboratory Investigation. 81, 7, p. 540-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes

    Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect

    Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors

    Falk-Petersen, C. B., Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In: Scientific Reports. 10, 1, 12 p., 10078.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2019
  10. Published

    Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)

    Leguizamon, Cesar Ramon Romero, Elnagar, M., Kristiansen, Uffe & Kohlmeier, Kristi Anne, 6 Feb 2019, In: Scientific Reports. p. 1 - 11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2018
  12. Published

    The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice

    von Schoubye, N. L., Frederiksen, K., Kristiansen, Uffe, Petersen, A. V., Dalby, N. O., Grunnet, M., Jensen, H. S., Jespersen, Thomas, Sohal, V. S. & Perrier, Jean-Francois Marie, 2018, In: Neuroscience Letters. 662, p. 29-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2017
  14. Published

    Anticonvulsive evaluation of THIP in the murine pentylenetetrazole kindling model: lack of anticonvulsive effect of THIP despite functional δ-subunit-containing GABAA receptors in dentate gyrus granule cells

    Simonsen, C., Boddum, K., von Schoubye, N. L., Kloppenburg, A., Sønderskov, K., Hansen, S. L. & Kristiansen, Uffe, Aug 2017, In: Pharmacology Research & Perspectives. 5, 4, 15 p., e00322.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2016
  16. Published

    Astrocytic GABA transporter activity modulates excitatory neurotransmission

    Boddum, K., Jensen, T. P., Magloire, V., Kristiansen, Uffe, Rusakov, D. A., Pavlov, I. & Walker, M. C., 25 Nov 2016, In: Nature Communications. 7, 10 p., 13572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors

    Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Uterine contraction induced by Ghanaian plants used to induce abortion

    Larsen, B. H., Soelberg, Jens, Kristiansen, Uffe & Jäger, A. K., 2016, In: South African Journal of Botany. 106, p. 137-39 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2015
  20. Published

    GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology

    Krall, J., Balle, T., Krogsgaard-Larsen, N., Sørensen, T. E., Krogsgaard-Larsen, Povl, Kristiansen, Uffe & Frølund, Bente, 2015, Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Vol. 72. p. 201-27 27 p. (Advances in Pharmacology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  21. 2014
  22. Published

    The GABAA Antagonist DPP-4-PIOL Selectively Antagonises Tonic over Phasic GABAergic Currents in Dentate Gyrus Granule Cells

    Boddum, K., Frølund, Bente & Kristiansen, Uffe, 8 Aug 2014, In: Neurochemical Research. 39, 11, p. 2078–2084 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Hippocampal P3-Like Auditory Event-Related Potentials are Disrupted in a Rat Model of Cholinergic Degeneration in Alzheimer's Disease: Reversal by Donepezil Treatment: Reversal by Donepezil Treatment

    Laursen, B., Mørk, A., Kristiansen, Uffe & Bastlund, J. F., 2 Jul 2014, In: Journal of Alzheimer's Disease. 42, 4, p. 1179–1189 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats

    Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2013
  26. Published

    Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration

    Laursen, B., Mørk, A., Plath, N., Kristiansen, Uffe & Bastlund, J. F., 11 Nov 2013, In: Brain Research. 1543, p. 253-262

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors

    Hoestgaard-Jensen, K., O'Connor, R. M., Dalby, N. O., Simonsen, C., Finger, B. C., Golubeva, A., Hammer, H., Bergmann, M. L., Kristiansen, Uffe, Krogsgaard-Larsen, Povl, Bräuner, Hans, Ebert, B., Frølund, Bente, Cryan, J. F. & Jensen, Anders A., Oct 2013, In: British Journal of Pharmacology. 170, 4, p. 919-32 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Leukocyte infiltration in experimental stroke

    Grønberg, N. V., Johansen, F. F., Kristiansen, Uffe & Hasseldam, Henrik, 18 Sep 2013, In: Journal of Neuroinflammation. 10, 9 p., 115.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Repeated potentiation of the metabotropic glutamate receptor 5 and the alpha 7 nicotinic acetylcholine receptor modulates behavioural and GABAergic deficits induced by early postnatal phencyclidine (PCP) treatment

    Kjærby, Celia, Bundgaard, C., Fejgin, K., Kristiansen, Uffe & Dalby, N. O., Sep 2013, In: Neuropharmacology. 72, p. 157-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice

    Laursen, B., Mørk, A., Plath, N., Kristiansen, Uffe & Bastlund, J. F., 1 Mar 2013, In: Behavioural Brain Research. 240, 1, p. 146-52 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Pharmacological evidence of functional inhibitory metabotrophic glutamate receptors on mouse arousal-related cholinergic laterodorsal tegmental neurons

    Kohlmeier, Kristi Anne, Christensen, M. H., Kristensen, M. P. & Kristiansen, Uffe, 2013, In: Neuropharmacology. 66, p. 99-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as ¿-aminobutyric acidA receptor agonists

    Petersen, J. G., Bergmann, R., Møller, H. A., Jørgensen, Charlotte Grube, Nielsen, Birgitte, Kehler, J., Frydenvang, Karla Andrea, Kristensen, Jesper Langgaard, Balle, T., Jensen, Anders A., Kristiansen, Uffe & Frølund, Bente, 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 993-1006

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2012
  34. Published

    Anti-histamine effect of Rubia tibetica, used to treat anaphylaxis caused by tick bites in the Pamir Mountains, Afghanistan

    Jeppesen, A. S., Kristiansen, Uffe, Soelberg, Jens & Jäger, A. K., 14 Jun 2012, In: Journal of Ethnopharmacology. 141, 3, p. 1077-1079 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  35. Published

    Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?

    Hansen, S. L., Sterjev, Z., Werngreen, M., Simonsen, B. J., Knudsen, K. E., Nielsen, A. H., Pedersen, M. E., Badolo, L., Kristiansen, Uffe & Vestergaard, H. T., May 2012, In: European Journal of Pharmacology. 682, 1-3, p. 43-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2011
  37. Published

    Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder

    Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In: Lægemiddelforskning. 2011, p. 23-25

    Research output: Contribution to journalJournal articleCommunication

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