Stefan Stürup

Stefan Stürup

Associate Professor


  1. 2024
  2. Published

    Determination of trace elements in ibuprofen drug products using microwave-assisted acid digestion and inductively coupled plasma-mass spectrometry

    Holmfred, Else Skovgaard, Alrijjal, A., Chamberlain, C. P., Maher, K. & Stürup, Stefan, 2024, In: Heliyon. 10, 1, 11 p., e23566.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Determination of Trace Elements in Ibuprofen Drug Products Using Microwave-Assisted Acid Digestion and Inductively Coupled Plasma-Mass Spectrometry

    Holmfred, Else Skovgaard, Alrijjal, A., Chamberlain, C. P., Maher, K. & Stürup, Stefan, 1 Aug 2023, Social Science Research Network (SSRN), 22 p. (JPBA-D-23-01192).

    Research output: Working paperPreprintResearch

  5. 2022
  6. Published

    In Vitro Characterization of a Threonine-Ligated Molybdenyl-Sulfide Cluster as a Putative Cyanide Poisoning Antidote: Intracellular Distribution, Effects on Organic Osmolyte Homeostasis, and Induction of Cell Death

    Gretarsdottir, J. M., Lambert, Ian Henry, Stürup, Stefan & Suman, S. G., 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 907–918

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells

    Lambert, Ian Henry, Nielsen, D. & Stürup, Stefan, 2020, In: American journal of physiology. Cell physiology. 318, 3, p. C581-C597

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2019
  10. Published

    Ex vivo toxicological evaluation of experimental anticancer gold(I) complexes with lansoprazole-type ligands

    Estrada-Ortiz, N., Lopez-Gonzales, E., Woods, B., Stürup, Stefan, de Graaf, I. A. M., Groothuis, G. M. M. & Casini, A., 1 Nov 2019, In: Toxicology Research. 8, 6, p. 885-895

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Development of a UPLC-IDA-ICP-MS/MS method for peptide quantitation in plasma by Se-labelling and comparison to S-detection of the native peptide

    Grønbæk-Thorsen, F., Stürup, Stefan, Gammelgaard, Bente & Møller, L. H., 2019, In: Journal of Analytical Atomic Spectrometry. 34, p. 375-383 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Distribution of platinum between nuclear and cytosolic fractions: can subcellular fractionation be performed quantitatively?

    Dam, C. S., Lambert, Ian Henry, Gammelgaard, Bente & Stürup, Stefan, 2019, In: Journal of Pharmaceutical and Biomedical Analysis. 165, p. 82-89 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin

    Han, J., Räder, A. F. B., Reichart, F., Aikman, B., Wenzel, M. N., Woods, B., Weinmüller, M., Ludwig, B. S., Stürup, Stefan, Groothuis, G. M. M., Permentier, H. P., Bischoff, R., Kessler, H., Horvatovich, P. & Casini, A., 21 Nov 2018, In: Bioconjugate Chemistry. 29, 11, p. 3856-3865 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies

    Azmi, I. D. M., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 5 Jun 2018, In: Langmuir : the ACS journal of surfaces and colloids. 34, 22, p. 6570-6581 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods

    Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Laser-assisted delivery enhances topical uptake of the anticancer agent cisplatin

    Wenande, E., Olesen, U. H., Boesen, M. R., Persson, Daniel Pergament, Lerche, C. M., Stürup, Stefan, Gammelgaard, Bente, Husted, Søren, Anderson, R. R. & Hædersdal, Merete, 2018, In: Drug Delivery. 25, 1, p. 1877-1885

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin

    Spreckelmeyer, S., van der Zee, M., Bertrand, B., Bodio, E., Stürup, Stefan & Casini, A., 2018, In: Frontiers in Chemistry. 6, 15 p., 377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2017
  20. Published

    Mitigating Cyanide Poisoning

    Suman, S. G., Gretarsdottir, J. M., Lambert, Ian Henry & Stürup, Stefan, Jul 2017, p. S261-S261.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  21. Published

    On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent

    Spreckelmeyer, S., Estrada-Ortiz, N., Prins, G. G. H., Van Der Zee, M., Gammelgaard, Bente, Stürup, Stefan, De Graaf, I. A. M., Groothuis, G. M. M. & Casini, A., 2017, In: Metallomics. 9, 12, p. 1786-1795 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Preparation of bis(5-phenyltetrazolato) Pt(II) and Pt(IV) analogues of transplatin and in vitro evaluation for antitumor activity

    Perfahl, S., Bodtke, A., Pracharova, J., Kasparkova, J., Brabec, V., Cuadrado, J., Stürup, Stefan, Schulzke, C. & Bednarski, P. J., 2017, In: Inorganica Chimica Acta. 456, p. 86-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2016
  24. Published

    Cellular uptake of metallated cobalamins

    Tran, M. T. Q., Stürup, Stefan, Lambert, Ian Henry, Gammelgaard, Bente, Furger, E. & Alberto, R., 2016, In: Metallomics. 8, 3, p. 298-304 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells

    Sørensen, B. H., Dam, C. S., Stürup, Stefan & Lambert, Ian Henry, 2016, In: Journal of Inorganic Biochemistry. 160, p. 287-295 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Quantification of low molecular weight selenium metabolites in human plasma after treatment with selenite in pharmacological doses by LC-ICP-MS

    Flouda, K., Dersch, J. M., Gabel-Jensen, C., Stürup, Stefan, Mistra, S., Björnstedt, M. & Gammelgaard, Bente, 2016, In: Analytical and Bioanalytical Chemistry. 408, 9, p. 2293-2301 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection

    Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2015
  29. Published

    Modulatory Effect of Human Plasma on the Internal Nanostructure and Size Characteristics of Liquid-Crystalline Nanocarriers

    Mat Azmi, I. D. B., Wu, L., Wibroe, P. P., Nilsson, C., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 30 Apr 2015, In: Langmuir. 31, 18, p. 5042–49 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid

    Dersch, J. M., Nguyen, T. T. T. N., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, Apr 2015, In: Analytical and Bioanalytical Chemistry. 407, 10, p. 2829-36 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin

    Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis

    Dam, C. S., Henarejos, S. A. P., Tsolakou, T., Segato, C. A., Gammelgaard, Bente, Yellol, G. S., Ruiz, J., Lambert, Ian Henry & Stürup, Stefan, 2015, In: Metallomics. 5, p. 885-895 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Evaluation of a membrane desolvator for LC-ICPMS analysis of selenium and platinum species for application to peptides and proteins

    Møller, L. H., Dam, C. S., Nguyen, T. T. T. N., Stürup, Stefan & Gammelgaard, Bente, 2015, In: Journal of Analytical Atomic Spectrometry. 30, 1, p. 277-284 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2014
  35. Published

    Quantification of pharmaceutical peptides using selenium as an elemental detection label

    Møller, L. H., Gabel-Jensen, C., Franzyk, Henrik, Bahnsen, J. S., Stürup, Stefan & Gammelgaard, Bente, 16 Jul 2014, In: Metallomics : integrated biometal science. 6, p. 1639-1647 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Environmental arsenic exposure, selenium and sputum alpha-1 antitrypsin

    Burgess, J. L., Kurzius-Spencer, M., Poplin, G. S., Littau, S. R., Kopplin, M. J., Stürup, Stefan, Boitano, S. & Clark Lantz, R., Mar 2014, In: Journal of Exposure Science and Environmental Epidemiology. 24, 2, p. 150-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2013
  38. Published

    Development and validation of an ICP-OES method for quantitation of elemental impurities in tablets according to coming US pharmacopeia chapters

    Jensen, C. S., Jensen, H., Gammelgaard, Bente & Stürup, Stefan, Oct 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 84, p. 209-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Determination of platinum drug release and liposome stability in human plasma by CE-ICP-MS

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 5 Jun 2013, In: International Journal of Pharmaceutics. 449, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Genome-wide association study of serum selenium concentrations

    Gong, J., Hsu, L., Harrison, T., B. King, I., Stürup, Stefan, Song, X., Duggan, D., Liu, Y., Hutter, C., J. Chanock, S., B. Eaton, C., R. Marshall, J. & Peters, U., 2013, In: Nutrients. 5, 5, p. 1706-1718 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Kvalitetssikring af målrettede nanopartikler til kemoterapi

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Lægemiddelforskning. 2012, p. 50-51

    Research output: Contribution to journalJournal articleCommunication

  42. Published

    Metallomics in drug development: characterization of a liposomal cisplatin drug formulation in human plasma by CE-ICP-MS

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Analytical and Bioanalytical Chemistry. 405, 6, p. 1845-1854

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2012
  44. Analytical Approaches for Assaying Metallodrugs in Biological Samples: Recent Methodological Developments and Future Trends

    Timerbaev, A. & Stürup, Stefan, 2012, In: Current Drug Metabolism. 13, 3, p. 272-283

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Assessing element-specific patterns of bioaccumulation across New England lakes

    Ward, D. M., Mayes, B., Stürup, Stefan, Folt, C. L. & Chen, C. Y., 2012, In: Science of the Total Environment. 421-422, 3-4, p. 230-237

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS

    Gammelgaard, Bente, Stürup, Stefan & Christensen, M. V., 2012, In: Metallomics. 4, 2, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Inductively coupled plasma mass spectrometry for analysis of metal-containing pharmaceuticals

    Gammelgaard, Bente, Stürup, Stefan & Møller, C., 2012, Encyclopedia of Drug Metabolism and Interactions. Lyubimov, A. V. (ed.). Wiley, Vol. 6. p. 1-25 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  48. Published

    Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In: Analytical and Bioanalytical Chemistry. 402, p. 2131-2139

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2011
  50. Published

    Determination of the binding sites for oxaliplatin on insulin using mass spectrometry-based approaches

    Møller, C., Sprenger, R. R., Stürup, Stefan & Højrup, P., 2011, In: Analytical and Bioanalytical Chemistry. 401, p. 1619-1629

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Investigation of the selenium metabolism in cancer cell lines

    Lunøe, K., Gabel-Jensen, C., Stürup, Stefan, Andresen, Lars, Skov, Søren & Gammelgaard, Bente, 2011, In: Metallomics. 3, 2, p. 162-168 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Quantitative HPLC-ICP-MC analysis of antimony redox speciation in complex sample matrices: new insights into the Sb-chemistry causing poor chromatographic recoveries

    Hansen, C., Schmidt, B., Larsen, E. H., Gammelgaard, Bente, Stürup, Stefan & Hansen, H. R., 2011, In: Analyst. 136, 5, p. 996-1002

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Reduction of Sb(V) in a human macrophage cell line measured by HPLC-ICP-MS

    Hansen, C., Hansen, E. W., Hansen, H. R., Gammelgaard, Bente & Stürup, Stefan, 2011, In: Biological Trace Element Research. 144, 1-3, p. 234-243

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Simultaneous measurement of phosphorus and platinum by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry (SEC-ICPMS) using xenon as reactive collision gas for charaterization of platinum drug liposomes

    Nguyen, T. T. N. T., Stürup, Stefan, Østergaard, Jesper, Franzen, U. & Gammelgaard, Bente, 2011, In: Journal of Analytical Atomic Spectrometry. 26, 7, p. 1466-1473

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2010
  56. Published

    Stability, accumulation and cytotoxicity of an albumin-cisplatin adduct

    Møller, C., Tastesen, H. S., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 1 Dec 2010, In: Metallomics. 2, 12, p. 811-818 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Pinpointing differences in cisplatin-induced apoptosis in adherent and non-adherent cancer cells

    Tastesen, H. S., Holm, J. B., Poulsen, K. A., Møller, C., Stürup, Stefan, Hoffmann, E. K. & Lambert, Ian Henry, 1 Jan 2010, In: Cellular Physiology and Biochemistry. 26, 6, p. 809-820 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    A method for analysis of dimethyl selenide and dimethyl diselenide by LC-ICP-DRC-MS

    Lunøe, K., Skov, S., Gabel-Jensen, C., Stürup, Stefan & Gammelgaard, Bente, 2010, In: Analytical and Bioanalytical Chemistry. 398, 7-8, p. 3081-3086

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Elevated antimony concentrations in commercial juices

    Hansen, C., Tsirigotaki, A., Bak, S. A., Pergantis, S. A., Stürup, Stefan, Gammelgaard, Bente & Hansen, H. R., 2010, In: Journal of Environmental Monitoring. 12, p. 822-824

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Ny viden om antimon - ny indsigt i glemt tropesygdom

    Hansen, C., Gammelgaard, Bente, Stürup, Stefan & Hansen, H. R., 2010, In: Lægemiddelforskning. 2010, p. 16-18

    Research output: Contribution to journalJournal articleCommunication

  61. Published

    Reply to comments on ‘Elevated antimony concentrations in commercial juices’

    Hansen, C., Tsirigotaki, A., Bak, S. A., Pergantis, S. A., Stürup, Stefan, Gammelgaard, Bente & Hansen, H. R., 2010, In: Journal of Environmental Monitoring. 12, p. 2308

    Research output: Contribution to journalLetterResearchpeer-review

  62. Published

    The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse

    Frost, A. B., Larsen, F., Larsen, Susan Weng, Østergaard, Jesper, Thomsen, M. H., Stürup, Stefan, Andersen, P. H. & Larsen, C. S., 2010, In: Pharmaceutical Research. 27, 1, p. 143-150 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2009
  64. Published

    Is Glutathione the Major Cellular Target of Cisplatin? A Study of the Interactions of Cisplatin with Cancer Cell Extracts

    Kasherman, Y., Stürup, Stefan & gibson, D., 18 Jun 2009, In: Journal of Medicinal Chemistry. 52, 14, p. 4319-4328 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Trans labilization of am(m)ine ligands from platinum (II) complexes by cancer cell extracts

    Kasherman, Y., Stürup, Stefan & Gibson, D., 2009, In: Journal of Biological Inorganic Chemistry. 14, 3, p. 387-399

    Research output: Contribution to journalJournal articleResearchpeer-review

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