Sine Larsen
Professor Emerita, Professor emeritus.
- 2021
- Published
The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme
Ramos, J., Laux, V., Haertlein, M., Forsyth, V. T., Mossou, E., Larsen, Sine & Langkilde, Annette Eva, 1 Dec 2021, In: Acta crystallographica Section D: Structural biology . 77, 12, p. 1579-1590 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme
Ramos, J. C. M., Laux, V., Haertlein, M., Boeri Erba, E., McAuley , K., Forsyth, V. T., Mossou, E., Larsen, Sine & Langkilde, Annette Eva, 2021, In: IUCrJ. 8, 3, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Insights into the composition of ancient Egyptian red and black inks on papyri achieved by synchrotron-based microanalyses
Christiansen, T., Cotte, M., de Nolf, W., Mouro, E., Reyes-Herrera, J., de Meyer, S., Vanmeert, F., Lindelof, Poul Erik, Salvadó, N., Mortensen, Kell, Ryholt, Kim, Janssens, K. & Larsen, Sine, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 45, p. 27825–27835 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The structural basis of fungal glucuronoyl esterase activity on natural substrates
Ernst, H. A., Mosbech, C., Langkilde, Annette Eva, Westh, P., Meyer, A. S., Wittrup Agger, J. & Larsen, Sine, 2020, In: Nature Communications. 11, 1026, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
A comparative structural analysis of the surface properties of asco-laccases
Ernst, H. A., Jørgensen, L. J., Bukh, C., Piontek, K., Plattner, D. A., Østergaard, L. H., Larsen, Sine & Bjerrum, Morten Jannik, 2018, In: PLoS ONE. 13, 11, p. 1-27 e0206589.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model
Skubak, P., Arac, D., Bowler, M. W., Correia, A. R., Hoelz, A., Larsen, Sine, Leonard, G. A., McCarthy, A. A., McSweeney, S., Mueller-Dieckmann, C., Otten, H., Salzman, G. & Pannu, N. S., 2018, In: I U Cr J. 5, Part 2, p. 166-171 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
The nature of ancient Egyptian copper-containing carbon inks is revealed by synchrotron radiation based X-ray microscopy
Christiansen, T., Cotte, M., Loredo-Portales, R., Lindelof, Poul Erik, Mortensen, Kell, Ryholt, Kim & Larsen, Sine, 10 Nov 2017, In: Scientific Reports. 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
The function of the milk-clotting enzymes bovine and camel chymosin studied by a fluorescence resonance energy transfer assay
Jensen, J. L., Jacobsen, J., Moss, M. L., Rasmussen, F., Qvist, K. B., Larsen, Sine & van den Brink, J. M., 2015, In: Journal of Dairy Science. 98, 5, p. 2853-2860 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystallography is more than crystal structures
Larsen, Sine, 2015, In: IUCrJ. 2, p. 475-476 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2014
- Published
A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study
Czene, A., Tóth, E., Németh, E., Otten, H., Poulsen, Jens-Christian Navarro, Christensen, H. E. M., Rulíšek, L., Nagata, K., Larsen, Sine & Gyurcsik, B., 2014, In: Metallomics. 6, 11, p. 2090-2099 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystallography and large research infrastructures, a perfect marriage
Larsen, Sine, 2014, In: IUCrJ. 1, Part 5, p. 261-262 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Polysaccharide lyase family 4
Lo Leggio, Leila & Larsen, Sine, 2014, Cazypedia.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Design of thermostable rhamnogalacturonan lyase mutants from Bacillus licheniformis by combination of targeted single point mutations
da Silva, I. I. C. R., Jers, C., Otten, H., Nyffenegger, C., Larsen, D. M., Derkx, P. M. F., Meyer, A. S., Mikkelsen, J. D. & Larsen, Sine, 2014, In: Applied Microbiology and Biotechnology. 98, 10, p. 4521-4531 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Molecular architecture of a complex between an adhesion protein from the malaria parasite and intracellular adhesion molecule 1
Brown, A., Turner, Louise, Christoffersen, S., Andrews, K. A., Szestak, T., Zhao, Y., Larsen, Sine, Craig, A. G. & Higgins, M. K., 22 Feb 2013, In: Journal of Biological Chemistry. 288, 8, p. 5992-6003 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystallization and preliminary crystallographic analysis of an Escherichia coli-selected mutant of the nuclease domain of the metallonuclease colicin E7
Czene, A., Toth, E., Gyurcsik, B., Otten, H., Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Larsen, Sine, Christensen, H. E. M. & Nagata, K., 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, p. 551-554 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Camel and bovine chymosin: the relationship between their structures and cheese-making properties
Jensen, J. L., Mølgaard, A., Poulsen, Jens-Christian Navarro, Harboe, M. K., Simonsen, J. B., Lorentzen, A. M., Hjernø, K., van den Brink, J. M., Qvist, K. B. & Larsen, Sine, 2013, In: Acta Crystallographica. Section D: Biological Crystallography. D69, p. 901-913 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The binding of zinc ions to Emericella nidulans endo-β-1,4-galactanase is essential for crystal formation
Otten, H., Michalak, M., Mikkelsen, J. D. & Larsen, Sine, 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. F69, 8, p. 850-854 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria
Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In: Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Understanding Thermodynamic Properties at the Molecular Level: Multiple Temperature Charge Density Study of Ribitol and Xylitol
Madsen, Anders Østergaard, Mattson, R. & Larsen, Sine, 2011, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 115, p. 7794–7804Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: Structure and function of a large, enigmatic family
Harris, P. V., Welner, D. H., McFarland, K., Re, E., Poulsen, Jens-Christian Navarro, Brown, K., Salbo, R., Ding, H., Vlasenko, E., Marino, S., Xu, F., Cherry, J., Larsen, Sine & Lo Leggio, Leila, 2010, In: Biochemistry. 49, p. 3305-3316Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and biochemical studies elucidate the mechanism of rhamnogalacturonan lyase from Aspergillus aculeatus
Jensen, M. H., Otten, H., Christensen, U., Borchert, T. V., Christensen, L. L. H., Larsen, Sine & Lo Leggio, Leila, 2010, In: Journal of Molecular Biology. 404, p. 100-111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Citations in supplementary material
Weiss, M. S., Einspahr, H., Baker, E. N., Dauter, Z., Kaysser-Pyzalla, A. R., Kostorz, G. & Larsen, Sine, 2010, In: Journal of Applied Crystallography. 43, p. 1285-1286Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Investigating the binding of beta-1,4-galactan to Bacillus licheniformis beta-1,4-galactanase by crystallography and computational modeling
Le Nours, J., De Maria, L., Welner, D. H., Jørgensen, C. T., Borchert, T. V., Christensen, L. L., Larsen, Sine & Lo Leggio, Leila, 2009, In: Proteins - Structure Function and Bioinformatics. 75, p. 977-989Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: a structural and pre-steady state kinetic analysis
Siggaard, J. H. B., Johansson, E., Vognsen, T. R., Helt, S. S., Harris, P., Larsen, Sine & Willemoës, Martin, 2009, In: Archives of Biochemistry and Biophysics. 490, 1, p. 42-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis
Helt, S. S., Thymark, M., Harris, P., Aagaard, C., Dietrich, J., Larsen, Sine & Willemoës, Martin, 2008, In: Journal of Molecular Biology. 376, 2, p. 554-69 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase
Langkilde, Annette Eva, Kristensen, S. M., Lo Leggio, Leila, Mølgaard, A., Jensen, Jan Halborg, Houk, A. R., Poulsen, Jens-Christian Navarro, Larsen, Sine & Kauppinen, S., 2008, In: Acta Crystallographica. Section D: Biological Crystallography. 64, p. 851-863Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimated H-atom anisotropic displacement parameters: a comparison between different methods and with neutron diffraction results
Munshi, P., Madsen, Anders Østergaard, Spackman, M. A., Larsen, Sine & Destro, R., 2008, In: Acta Crystallographica. Section A: Foundations of Crystallography. A64, p. 465-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Quaternary Structure and functional domains of the CI repressor from Bacteriophage TP901-1
Pedersen, M., Lo Leggio, Leila, Grossmann, J. G., Larsen, Sine & Hammer, K., 2008, In: Journal of Molecular Biology. 373, p. 983-996Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure and function of enzymes in biomass degradation
Welner, D. H., Jensen, M. H., McFarland, K. C., Poulsen, Jens-Christian Navarro, Otten, H., Salbo, R., Christensen, U., Harris, P., Larsen, Sine, Borchert, T., Christensen, L. L. H., Friis, E. P. & Lo Leggio, Leila, 2008, Biotechnology of lignocellulose degradation and Biomass Utilization - Mie Bioforum 2008. p. 349-355Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- 2007
- Published
Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme
Johansson, E., Thymark, M., Bynck, J. H., Fanø, M., Larsen, Sine & Willemoës, Martin, 2007, In: FEBS Journal. 274, 16, p. 4188-4198 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insight into Solid-State Entropy from Diffraction Data
Madsen, Anders Østergaard & Larsen, Sine, 2007, In: Angewandte Chemie - International Edition. 46, 45, p. 8609-8613Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The crystal structure of human dipeptidyl peptidase I (cathepsin C) in complex with the inhibitor Gly-Phe-CHN2
Mølgaard, A., Arnau, J., Lauritzen, C., Larsen, Sine, Petersen, G. & Pedersen, J., 2007, In: Biochemical Journal. 401, 3, p. 645-50 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase
Thymark, M., Johansson, E., Larsen, Sine & Willemoës, Martin, 2007, In: Archives of Biochemistry and Biophysics. 470, 1, p. 20-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of benzoate pyrimidine analogues with class 1A dihydroorotate dehydrogenase from Lactococcus lactis
Wolfe, A. E., Thymark, M., Gattis, S. G., Fagan, R. L., Hu, Y., Johansson, E., Arent, S., Larsen, Sine & Palfey, B. A., 2007, In: Biochemistry. 46, 19, p. 5741-53 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
The extraordinary specificity of xanthine phosphoribosyltransferase from Bacillus subtilis elucidated by reaction kinetics, ligand binding, and crystallography
Arent, S., Kadziola, Anders, Larsen, Sine, Neuhard, J. & Jensen, K. F., 2006, In: Biochemistry. 45, 21, p. 6615-6627Research output: Contribution to journal › Journal article › Research › peer-review
High-throughput sample handling and data collection at synchrotrons: embedding the ESRF in the high-throughput gene-to-structure pipeline
Beteva, A., Cipriani, F., Cusack, S., Delageniere, S., Gabadinho, J., Gordon, E. J., Guijarro, M., Hall, D. R., Larsen, S., Launer, L., Lavault, C. B., Leonard, G. A., Mairs, T., McCarthy, A., McCarthy, J., Meyer, J., Mitchell, E., Monaco, S., Nurizzo, D., Pernot, P. & 12 others, , 2006, In: Acta Crystallographica. Section D: Biological Crystallography. 62, 10, p. 1162-1169 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Automation of sample mounting for macromolecular crystallography
Cipriani, F., Felisaz, F., Launer, L., Aksoy, J., Caserotto, H., Cusack, S., Dallery, M., di-Chiaro, F., Guijarr, M., Huet, J., Larsen, Sine, Lentini, M., McCarthy, J., McSweeeney, S., Ravelli, R., Renier, M., Taffut, C., Thompson, A., Leonard, G. A. & Walsh, M. A., 2006, In: Acta Crystallographica. Section D: Biological Crystallography. 62, 10, p. 1251-1259 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31
Ernst, H. A., Lo Leggio, Leila, Willemoës, Martin, Leonard, G. A., Blum, P. & Larsen, Sine, 2006, In: Journal of Molecular Biology. 358, 4, p. 1106-24Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Allosteric regulation and communication between subunits in uracil phosphoribosyltransferase from Sulfolobus solfataricus
Arent, S., Harris, P., Jensen, K. F. & Larsen, Sine, 2005, In: Biochemistry. 44, 3, p. 883-892Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Facile cobalt(III) template synthesis of novel branched hexadentate polyamine monocarboxylates
Barfod, R., Eriksen, J., Golding, B. T., Hammershøi, Anders, Jacobsen, T. A., Langkilde, Annette Eva, Larsen, Sine, Mønsted, O., Sargeson, A. M. & Sørensen, H. O., 2005, In: Dalton Transactions (Print Edition). 3, p. 491-500 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of different crystal forms of the a-glucosidase MalA from Sulfolobus solfataricus
Ernst, H. A., Willemoës, Martin, Lo Leggio, Leila, Leonard, G., Blum, P. & Larsen, Sine, 2005, In: Acta Crystallographica Section F. 61, p. 1039-1042Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of different crystal forms of the alpha-glucosidase MalA from Sulfolobus solfataricus
Ernst, H. A., Willemoës, Martin, Lo Leggio, Leila, Leonard, G., Blum, P. & Larsen, Sine, 2005, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 61, Pt 12, p. 1039-42 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the structure of glucan lyases by sequence analysis, circular dichroism and proteolysis
Ernst, H. A., Lo Leggio, Leila, Yu, S., Finnie, C., Svensson, B. & Larsen, Sine, 2005, In: Biologia. 60, Suppl. 16, p. 149-159Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Allosteric properties of the GTP activated and CTP inhibited uracil phosphoribosyltransferase from the thermoacidophilic archeon Sulfolobus solfataricus
Jensen, K. F., Arent, S., Larsen, Sine & Schack, L., 2005, In: FEBS Journal. 272, p. 1440-1453Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Allosteric regulation of the GTP activated and CTP inhibited uracil phosphoribosyltransferase from the thermophilic archaeon Sulfolobus solfataricus
Jensen, K. F., Arent, S., Larsen, Sine & Schack, L., 2005, In: FEBS Journal. 272, 6, p. 1440-1453Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structures of dCTP deaminase from Escherichia coli with bound substrate and product
Johansson, E. H., Fanø, M., Bynck, J. H., Neuhard, J., Larsen, Sine, Sigurdskjold, B., Christensen, U. & Willemoës, M., 2005, In: The Journal of Biological Chemistry. 280, p. 3051-3059Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii.
Kadziola, Anders, Jepsen, C. H., Johansson, E., McGuire, J., Larsen, Sine & Hove-Jensen, B., 2005, In: Journal of Molecular Biology. 354, 4, p. 815-28 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and analysis of 21 novel disease-causing amino acid substitutions in the conserved part of ATP7A
Møller, L. B., Bukrinsky, J. T., Mølgaard, A., Paulsen, M., Lund, C., Tümer, Z., Larsen, Sine & Horn, N., 2005, In: Human Mutation. 26, p. 84-93Research output: Contribution to journal › Journal article › Research › peer-review
- Published
2-(1-Naphthyl)propionic acid
Riis, E. P. & Larsen, Sine, 2005, In: Acta Crystallographica. Section E: Structure Reports Online. E61, p. o1396-o1397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetra-tert-butyl-di-μ-hydroxo digallium(III) and 1,12-diaza-3,4:9,10- dibenzo-5,8-dioxo-cyclo-pentadecane. Structure and isomers of the coordination compound
Sun, H., Thulstrup, Peter Waaben, Larsen, Sine & Larsen, Erik, 1 Nov 2005, In: International Journal of Molecular Sciences. 6, 11, p. 276-290 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8853
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Crystallography is more than crystal structures
Research output: Contribution to journal › Editorial › Research › peer-review
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167
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Crystallography and large research infrastructures, a perfect marriage
Research output: Contribution to journal › Editorial › Research › peer-review
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139
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A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model
Research output: Contribution to journal › Journal article › Research › peer-review
Published