Sergey Vakhrushev
Associate Professor
Glycomics Program
Blegdamsvej 3
2200 København N.
- 2023
- Published
A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution
Chen, Yen-Hsi, Tian, W., Yasuda, M., Ye, Z., Song, Ming, Mandel, Ulla, Kristensen, C., Povolo, Lorenzo, Marques, A. R. A., Čaval, T., Heck, A. J. R., Sampaio, J. L., Johannes, L., Tsukimura, T., Desnick, R., Vakhrushev, Sergey, Yang, Zhang & Clausen, Henrik, 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1128371.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., thor Straten, Per, Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Larsen, I. S. B., Povolo, Lorenzo, Zhou, L., Tian, W., Mygind, Kasper Johansen, Hintze, John, Jiang, C., Hartill, V., Prescott, K., Johnson, C. A., Mullegama, S. V., McConkie-Rosell, A., McDonald, M., Hansen, Lars, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Worzfeld, T., Joshi, Hiren Jitendra & Halim, Adnan, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 21, p. e2302584120Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C- and O-Mannosylated Peptides
Hütte, H. J., Tiemann, B., Shcherbakova, A., Grote, V., Hoffmann, M., Povolo, Lorenzo, Lommel, M., Strahl, S., Vakhrushev, Sergey, Rapp, E., Buettner, F. F. R., Halim, Adnan, Imberty, A. & Bakker, H., 2022, In: Analytical Chemistry. 94, 20, p. 7329–7338Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
Coelho, H., Rivas, M. D. L., Grosso, A. S., Diniz, A., Soares, C. O., Francisco, R. A., Dias, J. S., Compañon, I., Sun, L., Narimatsu, Yoshiki, Vakhrushev, Sergey, Clausen, Henrik, Cabrita, E. J., Jiménez-Barbero, J., Corzana, F., Hurtado-Guerrero, R. & Marcelo, F., 2022, In: JACS Au. 2, 3, p. 631-645 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CNOT6: A Novel Regulator of DNA Mismatch Repair
Song, P., Liu, S., Liu, D., Keijzers, Guido, Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth
Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the glycosylation of mucins by use of O-glycodomain reporters recombinantly expressed in glycoengineered HEK293 cells
Konstantinidi, Andriana, Nason, R., Čaval, T., Sun, L., Sørensen, Daniel Madriz, Furukawa, S., Ye, Z., Vincentelli, R., Narimatsu, Yoshiki, Vakhrushev, Sergey & Clausen, Henrik, 2022, In: Journal of Biological Chemistry. 298, 4, 101784.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global mapping of GalNAc-T isoform-specificities and O-glycosylation site-occupancy in a tissue-forming human cell line
Nielsen, Mathias Alexander Ingemann, de Haan, Noortje, Kightlinger, W., Ye, Z., Dabelsteen, Sally, Li, Minyan, Jewett, M. C., Bagdonaite, Ieva , Vakhrushev, Sergey & Wandall, Hans H., 2022, In: Nature Communications. 13, 17 p., 6257.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycoproteomics
Bagdonaite, Ieva , Malaker, S. A., Polasky, D. A., Riley, N. M., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Halim, Adnan, Aoki-Kinoshita, K. F., Nesvizhskii, A. I., Bertozzi, C. R., Wandall, Hans H., Parker, B. L., Thaysen-Andersen, M. & Scott, N. E., 2022, In: Nature Reviews Methods Primers. 2, 1, 48.Research output: Contribution to journal › Review › Research › peer-review
ID: 21237349
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162
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
117
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A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
95
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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Research output: Contribution to journal › Review › Research › peer-review
Published