Sergey Vakhrushev

Sergey Vakhrushev

Associate Professor


  1. 2023
  2. Published

    A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

    Chen, Yen-Hsi, Tian, W., Yasuda, M., Ye, Z., Song, Ming, Mandel, Ulla, Kristensen, C., Povolo, Lorenzo, Marques, A. R. A., Čaval, T., Heck, A. J. R., Sampaio, J. L., Johannes, L., Tsukimura, T., Desnick, R., Vakhrushev, Sergey, Yang, Zhang & Clausen, Henrik, 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1128371.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

    Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., thor Straten, Per, Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Identification of global inhibitors of cellular glycosylation

    Sørensen, D. M., Büll, C., Madsen, T. D., Lira-Navarrete, E., Clausen, T. M., Clark, A. E., Garretson, A. F., Karlsson, R., Pijnenborg, J. F. A., Yin, X., Miller, R. L., Chanda, S. K., Boltje, T. J., Schjoldager, K. T., Vakhrushev, S. Y., Halim, A., Esko, J. D., Carlin, A. F., Hurtado-Guerrero, R., Weigert, R. & 2 others, Clausen, Henrik & Narimatsu, Yoshiki, 2023, In: Nature Communications. 14, 1, 19 p., 948.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Sensitive and Specific Global Cell Surface N-Glycoproteomics Shows Profound Differences Between Glycosylation Sites and Subcellular Components

    de Haan, Noortje, Song, Ming, Grant, O. C., Ye, Z., Khoder Agha, F., Aasted, Mikkel Koed Møller, Woods, R. J., Vakhrushev, Sergey & Wandall, Hans H., 2023, In: Analytical Chemistry. 95, 47, p. 17328-17336 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase

    Larsen, I. S. B., Povolo, Lorenzo, Zhou, L., Tian, W., Mygind, Kasper Johansen, Hintze, John, Jiang, C., Hartill, V., Prescott, K., Johnson, C. A., Mullegama, S. V., McConkie-Rosell, A., McDonald, M., Hansen, Lars, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Worzfeld, T., Joshi, Hiren Jitendra & Halim, Adnan, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 21, p. e2302584120

    Research output: Contribution to journalJournal articlepeer-review

  7. 2022
  8. Published

    A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C- and O-Mannosylated Peptides

    Hütte, H. J., Tiemann, B., Shcherbakova, A., Grote, V., Hoffmann, M., Povolo, Lorenzo, Lommel, M., Strahl, S., Vakhrushev, Sergey, Rapp, E., Buettner, F. F. R., Halim, Adnan, Imberty, A. & Bakker, H., 2022, In: Analytical Chemistry. 94, 20, p. 7329–7338

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling

    Coelho, H., Rivas, M. D. L., Grosso, A. S., Diniz, A., Soares, C. O., Francisco, R. A., Dias, J. S., Compañon, I., Sun, L., Narimatsu, Yoshiki, Vakhrushev, Sergey, Clausen, Henrik, Cabrita, E. J., Jiménez-Barbero, J., Corzana, F., Hurtado-Guerrero, R. & Marcelo, F., 2022, In: JACS Au. 2, 3, p. 631-645 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    CNOT6: A Novel Regulator of DNA Mismatch Repair

    Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

    Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Exploring the glycosylation of mucins by use of O-glycodomain reporters recombinantly expressed in glycoengineered HEK293 cells

    Konstantinidi, Andriana, Nason, R., Čaval, T., Sun, L., Sørensen, Daniel Madriz, Furukawa, S., Ye, Z., Vincentelli, R., Narimatsu, Yoshiki, Vakhrushev, Sergey & Clausen, Henrik, 2022, In: Journal of Biological Chemistry. 298, 4, 101784.

    Research output: Contribution to journalJournal articlepeer-review

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ID: 21237349