Pontus Emanuel Gourdon

Pontus Emanuel Gourdon

Associate Professor


  1. 2020
  2. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin

    He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In : Redox Biology. 36, 11 p., 101631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

    Kitchen, P., Salman, M. M., Halsey, A. M., Clarke-Bland, C., MacDonald, J. A., Ishida, H., Vogel, H. J., Almutiri, S., Logan, A., Kreida, S., Al-Jubair, T., Missel, Julie Winkel, Gourdon, Pontus Emanuel, Törnroth-Horsefield, S., Conner, M. T., Ahmed, Z., Conner, A. C. & Bill, R. M., 2020, In : Cell. 181, 4, p. 784-799

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The rapid “teabag” method for high-end purification of membrane proteins

    Hering, J., Missel, Julie Winkel, Zhang, Liying, Gunnarsson, A., Castaldo, M., Pedersen, Per Amstrup, Ek, M., Gourdon, Pontus Emanuel & Snijder, H. J., 2020, In : Scientific Reports. 10, 11 p., 16167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The transport mechanism of P4 ATPase lipid flippases

    Lopez Marques, Rosa Laura, Gourdon, Pontus Emanuel, Günther-Pomorski, Thomas & Palmgren, Michael, 2020, In : Biochemical Journal. 477, 19, p. 3769-3790 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

    Gotfryd, Kamil, Boesen, T., Mortensen, J. S., Khelashvili, G., Quick, M., Terry, D. S., Missel, Julie Winkel, LeVine, M. V., Gourdon, Pontus Emanuel, Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, Claus Juul, Nissen, P. & Gether, Ulrik, 2020, In : Nature Communications. 11, 1, 14 p., 1005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2019
  8. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, Liying, Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, Kamil, 2019, In : Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, Liying, Cui, Y., Missel, Julie Winkel, Grønberg, Christina, Gotfryd, Kamil, Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In : PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2018
  11. Published

    Human adipose glycerol flux is regulated by a pH gate in AQP10

    Gotfryd, Kamil, Mósca, A. F., Missel, Julie Winkel, Truelsen, S. F., Wang, Kaituo, Spulber, M., Krabbe, S., Hélix-nielsen, C., Laforenza, U., Soveral, G., Pedersen, Per Amstrup & Gourdon, Pontus Emanuel, 2018, In : Nature Communications. 9, p. 1-11 4749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Interactions of a Bacterial Cu(I)-ATPase with a Complex Lipid Environment

    Autzen, Henriette Elisabeth, Koldso, H., Stansfeld, P. J., Gourdon, Pontus Emanuel, Sansom, M. S. P. & Nissen, P., 2018, In : Biochemistry. 57, 28, p. 4063-4073

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Isolation and Characterization of Nanobodies against a Zinc-Transporting P-Type ATPase

    Longhin, E., Grønberg, Christina, Hu, Q., Duelli, A. S., Andersen, K. R., Laursen, N. S. & Gourdon, Pontus Emanuel, 2018, In : Antibodies. 7, 4, 15 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function

    Lindahl, V., Gourdon, Pontus Emanuel, Andersson, M. & Hess, B., 2018, In : Scientific Reports. 8, 13 p., 2995 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    Purification and functional comparison of nine human Aquaporins produced in Saccharomyces cerevisiae for the purpose of biophysical characterization

    Bjørkskov, F. B., Krabbe, S., Nurup, C. N., Missel, Julie Winkel, Spulber, M., Bomholt, J., Molbaek, Karen, Helix-Nielsen, C., Gotfryd, Kamil, Gourdon, Pontus Emanuel & Pedersen, Per Amstrup, 4 Dec 2017, In : Scientific Reports. 7, 21 p., 16899.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

    Skjørringe, T., Pedersen, Per Amstrup, Thorborg, S. S., Nissen, P., Gourdon, Pontus Emanuel & Møller, L. B., 7 Apr 2017, In : Scientific Reports. 7, 18 p., 757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Phospholipid flipping involves a central cavity in P4 ATPases

    Jensen, M. S., Costa, S., Duelli, A. S., Andersen, P. A., Pedas, Lisbeth Rosager, Stanchev, Lyubomir, Gourdon, Pontus Emanuel, Palmgren, Michael, Günther-Pomorski, Thomas & Lopez Marques, Rosa Laura, 2017, In : Scientific Reports. 7, 13 p., 17621.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2016
  20. Published

    Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport

    Grønberg, Christina, Sitsel, O., Lindahl, E., Gourdon, Pontus Emanuel & Andersson, M., 6 Dec 2016, In : Biophysical Journal. 111, 11, p. 2417-2429 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Initiating heavy-atom-based phasing by multi-dimensional molecular replacement

    Pedersen, B. P., Gourdon, Pontus Emanuel, Liu, X., Karlsen, J. L. & Nissen, P., 1 Mar 2016, In : Acta crystallographica Section D: Structural biology . 72, 3, p. 440-445 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Crystal Structure of an Ammonia-Permeable Aquaporin

    Kirscht, A., Kaptan, S. S., Bienert, G. P., Chaumont, F., Nissen, P., de Groot, B. L., Kjellbom, P., Gourdon, Pontus Emanuel & Johanson, U., Mar 2016, In : PLoS Biology. 14, 3, 19 p., e1002411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Crystallization of P-type ATPases by the High Lipid-Detergent (HiLiDe) Method

    Sitsel, O., Wang, Kaituo, Liu, X. & Gourdon, Pontus Emanuel, 2016, P-Type ATPases: Methods and Protocols. Bublitz, M. (ed.). Springer, Vol. 1377. p. 413-420 8 p. (Methods in Molecular Biology, Vol. 1377).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Overproduction of PIB-Type ATPases

    Liu, X., Sitsel, O., Wang, Kaituo & Gourdon, Pontus Emanuel, 2016, P-Type ATPases: Methods and Protocols. Bublitz, M. (ed.). Springer, Vol. 1377. p. 29-36 8 p. (Methods in Molecular Biology, Vol. 1377).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  25. 2015
  26. Published

    Structure and Function of Cu(I)- and Zn(II)-ATPases

    Sitsel, O., Grønberg, Christina, Autzen, Henriette Elisabeth, Wang, Kaituo, Meloni, G., Nissen, P. & Gourdon, Pontus Emanuel, 22 Sep 2015, In : Biochemistry. 54, 37, p. 5673-5683 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. A sulfur-based transport pathway in Cu+-ATPases

    Mattle, D., Zhang, L., Sitsel, O., Pedersen, L. T., Moncelli, M. R., Tadini-Buoninsegni, F., Gourdon, Pontus Emanuel, Rees, D. C., Nissen, P. & Meloni, G., 1 Jun 2015, In : E M B O Reports. 16, 6, p. 728-470 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2014
  29. Published

    Structure and mechanism of Zn2+-transporting P-type ATPases

    Wang, Kaituo, Sitsel, O., Meloni, G., Autzen, Henriette Elisabeth, Andersson, M., Klymchuk, T., Nielsen, A. M., Rees, D. C., Nissen, P. & Gourdon, Pontus Emanuel, 23 Oct 2014, In : Nature. 514, 7523, p. 518-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Initiating Heavy-atom Based Phasing by Multi-Dimensional Molecular Replacement

    Pedersen, B. P., Gourdon, Pontus Emanuel, Liu, X., Karlsen, J. L. & Nissen, P., 28 Mar 2014, In : arXiv. p. 1-19 19 p.

    Research output: Contribution to journalJournal articleResearch

  31. Published

    Copper-transporting P-type ATPases use a unique ion-release pathway

    Andersson, M., Mattle, D., Sitsel, O., Klymchuk, T., Nielsen, A. M., Moller, L. B., White, S. H., Nissen, P. & Gourdon, Pontus Emanuel, Jan 2014, In : Nature Structural and Molecular Biology. 21, 1, p. 43-48 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate

    Azouaoui, H., Montigny, C., Ash, M., Fijalkowski, F. A., Jacquot, A., Grønberg, Christina, Lopez Marques, Rosa Laura, Palmgren, Michael, Garrigos, M., le Maire, M., Decottignies, P., Gourdon, Pontus Emanuel, Nissen, P., Champeil, P. & Lenoir, G., 2014, In : PloS one. 9, 11, p. 1-16 16 p., e112176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2013
  34. Published

    Heterologous expression and purification of an active human TRPV3 ion channel

    Kol, S., Braun, C. S., Thiel, G., Doyle, D. A., Sundström, M., Gourdon, Pontus Emanuel & Nissen, P., 1 Dec 2013, In : The F E B S Journal (Online). 280, 23, p. 6010-6021 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Crystal Structure of Na+, K+-ATPase in the Na+-Bound State

    Nyblom, M., Poulsen, H., Gourdon, Pontus Emanuel, Reinhard, L., Andersson, M., Lindahl, E., Fedosova, N. & Nissen, P., 4 Oct 2013, In : Science. 342, 6154, p. 123-127

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    On Allosteric Modulation of P-Type Cu+-ATPases

    Mattle, D., Sitsel, O., Autzen, Henriette Elisabeth, Meloni, G., Gourdon, Pontus Emanuel & Nissen, P., 10 Jul 2013, In : Journal of Molecular Biology. 425, 13, p. 2299-2308

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2012
  38. Published

    Structural models of the human copper P-type ATPases ATP7A and ATP7B

    Gourdon, Pontus Emanuel, Sitsel, O., Karlsen, J. L., Moller, L. B. & Nissen, P., Apr 2012, In : Biological Chemistry. 393, 4, p. 205-216

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2011
  40. Published

    Crystal structure of a copper-transporting PIB-type ATPase

    Gourdon, Pontus Emanuel, Liu, X., Skjørringe, T., Morth, J. P., Møller, L. B., Pedersen, B. P. & Nissen, P., 7 Jul 2011, In : Nature. 475, 7354, p. 59-64 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Crystallization and preliminary structural analysis of the Listeria monocytogenes Ca2+-ATPase LMCA1

    Andersen, J. L., Gourdon, Pontus Emanuel, Moller, J. V., Morth, J. P. & Nissen, P., Jun 2011, In : Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 67, p. 718-722

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    HiLiDe-Systematic Approach to Membrane Protein Crystallization in Lipid and Detergent

    Gourdon, Pontus Emanuel, Andersen, J. L., Hein, K. L., Bublitz, M., Pedersen, B. P., Liu, X., Yatime, L., Nyblom, M., Nielsen, T. T., Olesen, C., Moller, J. V., Nissen, P. & Morth, J. P., Jun 2011, In : Crystal Growth & Design. 11, 6, p. 2098-2106

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Characterization of a Listeria monocytogenes Ca2+ Pump A SERCA-TYPE ATPase WITH ONLY ONE Ca2+-BINDING SITE

    Faxen, K., Andersen, J. L., Gourdon, Pontus Emanuel, Fedosova, N., Morth, J. P., Nissen, P. & Moller, J. V., 14 Jan 2011, In : Journal of Biological Chemistry. 286, 2, p. 1609-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2008
  45. Published

    Optimized in vitro and in vivo expression of proteorhodopsin: A seven-transmembrane proton pump

    Gourdon, Pontus Emanuel, Alfredsson, A., Pedersen, A., Mahnerberg, E., Nyblom, M., Widell, M., Berntsson, R., Pinhassi, J., Braiman, M., Hansson, O., Bonander, N., Karlsson, G. & Neutze, R., Mar 2008, In : Protein Expression and Purification. 58, 1, p. 103-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2007
  47. Published

    Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist

    Toernroth-Horsefield, S., Gourdon, Pontus Emanuel, Horsefield, R., Brive, L., Yamamoto, N., Mori, H., Snijder, A. & Neutze, R., Dec 2007, In : Structure. 15, 12, p. 1663-1673

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Light stimulates growth of proteorhodopsin-containing marine Flavobacteria

    Gomez-Consarnau, L., Gonzalez, J. M., Coll-Llado, M., Gourdon, Pontus Emanuel, Pascher, T., Neutze, R., Pedros-Alio, C. & Pinhassi, J., 11 Jan 2007, In : Nature. 445, 7124, p. 210-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2006
  50. Published

    Picosecond calorimetry: Time-resolved x-ray diffraction studies of liquid CH2Cl2

    Georgiou, P., Vincent, J., Andersson, M., Wöhri, A. B., Gourdon, Pontus Emanuel, Poulsen, J., Davidsson, J. & Neutze, R., 21 Jun 2006, In : Journal of Chemical Physics. 124, 23, 234507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2005
  52. Published

    Conformational regulation of charge recombination reactions in a photosynthetic bacterial reaction center

    Katona, G., Snijder, A., Gourdon, Pontus Emanuel, Andréasson, U., Hansson, O., Andréasson, L. & Neutze, R., Jul 2005, In : Nature Structural and Molecular Biology. 12, 7, p. 630-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2003
  54. Published

    Functional split and crosslinking of the membrane domain of the beta subunit of proton-translocating transhydrogenase from Escherichia coli

    Althage, M., Karlsson, J., Gourdon, Pontus Emanuel, Levin, M., Bill, R., Tigerstrom, A. & Rydstrom, J., 23 Sep 2003, In : Biochemistry. 42, 37, p. 10998-11003

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 108586181