Philip Allan Seymour

Philip Allan Seymour

Assistant professor


  1. 2020
  2. Published

    Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development

    Liu, D., Kousa, A. I., O'Neill, K. E., Rouse, P., Popis, M., Farley, A. M., Tomlinson, S. R., Ulyanchenko, Svetlana, Guillemot, F., Seymour, Philip Allan, Jørgensen, Mette Christine, Serup, Palle, Koch, U., Radtke, F. & Blackburn, C. C., 2020, In: Development (Cambridge, England). 147, p. 1-16 dev178582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

    Seymour, Philip Allan, Collin, C. A., Egeskov-Madsen, A. L. R., Jørgensen, Mette Christine, Shimojo, H., Imayoshi, I., de Lichtenberg, K. H., Kopan, R., Kageyama, R. & Serup, Palle, 2020, In: Developmental Cell. 52, 6, p. 731-747.e8 26 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2019
  5. Published

    Mesodermal induction of pancreatic fate commitment

    Seymour, Philip Allan & Serup, Palle, Aug 2019, In: Seminars in Cell and Developmental Biology. 92, p. 77-88

    Research output: Contribution to journalReviewResearchpeer-review

  6. 2018
  7. Published

    Mechanosignalling via integrins directs fate decisions of pancreatic progenitors

    Mamidi, A., Prawiro, C., Seymour, Philip Allan, de Lichtenberg, K. H., Jackson, Abigail Laura, Serup, Palle & Semb, Tor Henrik, Dec 2018, In: Nature. 564, 7734, p. 114-118 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  8. Published

    Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors

    Liu, K., Leuckx, G., Sakano, D., Seymour, Philip Allan, Mattsson, C. L., Rautio, L., Staels, W., Verdonck, Y., Serup, Palle, Kume, S., Heimberg, H. & Andersson, O., Jan 2018, In: Diabetes. 67, 1, p. 58-70 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. E-pub ahead of print

    Notch controls multiple pancreatic cell fate regulators through direct hes1-mediated repression.

    de Lichtenberg, K. H., Seymour, Philip Allan, Jørgensen, Mette Christine, Kim, Y., Grapin-Botton, A., Magnuson, M. A., Nakic, N., Ferrer, J. & Serup, Palle, 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-30 30 p.

    Research output: Contribution to journalJournal articleResearch

  10. 2016
  11. Published

    Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo

    Horn, S., Kirkegaard, J. S., Hoelper, S., Seymour, Philip Allan, Rescan, C., Nielsen, Jens Høiriis, Madsen, O. D., Jensen, J. N., Kruger, M., Gronborg, M. & Ahnfelt-Rønne, J., 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 133-143 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2015
  13. Published

    A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells

    Shih, H. P., Seymour, Philip Allan, Patel, N. A., Xie, R., Wang, A., Liu, P. P., Yeo, G. W., Magnuson, M. A. & Sander, M., 13 Oct 2015, In: Cell Reports. 13, 2, p. 326-36 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Pairing-up SOX to kick-start beta cell genesis

    Botton, Anne, Seymour, Philip Allan & Gradwohl, G., May 2015, In: Diabetologia. 58, 5, p. 859-861 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A conserved role for Notch in priming the cellular response to Shh through ciliary localisation of the key Shh transducer, Smoothened

    Stasiulewicz, M., Gray, S., Mastromina, I., Silva, J. C., Bjorklund, M., Seymour, Philip Allan, Booth, D., Thompson, C., Green, R., Hall, E. A., Serup, Palle & Dale, J. K., 2015, In: Development. 142, p. 2291-2303 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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