Per Mårten Hägglund
Associate Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- 2016
- Published
Seed thioredoxin h
Hägglund, Per Mårten, Finnie, C., Yano, H., Shahpiri, A., Buchanan, B. B., Henriksen, A. & Svensson, B., 1 Aug 2016, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1864, 8, p. 974-982 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
A redox-dependent dimerization switch regulates activity and tolerance for reactive oxygen species of barley seed glutathione peroxidase
Navrot, N., Skjoldager, N., Bunkenborg, J., Svensson, B. & Hägglund, Per Mårten, 2015, In: Plant Physiology and Biochemistry. 90, p. 58-63 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lactococcus lactis Thioredoxin Reductase is Sensitive to Light Inactivation
Björnberg, O., Viennet, T., Skjoldager, N., Ćurović, A., Nielsen, K. F., Svensson, B. & Hägglund, Per Mårten, 2015, In: Biochemistry. 54, 8, p. 1628-1637 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders
Kristensen, J. H., Larsen, L., Dasgupta, B., Brodmerkel, C., Curran, M., Karsdal, M. A., Sand, J. M. B., Willumsen, N., Knox, A. J., Bolton, C. E., Johnson, S. R., Hägglund, Per Mårten, Svensson, B. & Leeming, D. J., 2015, In: Clinical Biochemistry. 48, 16-17, p. 1083-1088 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling
Kristensen, J. H., Karsdal, M. A., Sand, J. M. B., Willumsen, N., Diefenbach, C., Svensson, B., Hägglund, Per Mårten & Oersnes-Leeming, D. J., 2015, In: BMC Pulmonary Medicine. 15, 1, 53.Research output: Contribution to journal › Journal article › Research › peer-review
Two Lactococcus lactis thioredoxin paralogues play different roles in responses to arsenate and oxidative stress
Efler, P., Kilstrup, M., Johnsen, S., Svensson, B. & Hägglund, Per Mårten, 2015, In: Microbiology (United Kingdom). 161, 3, p. 528-538 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Glycopeptide enrichment using a combination of ZIC-HILIC and cotton wool for exploring the glycoproteome of wheat flour albumins
Dedvisitsakul, P., Jacobsen, S., Svensson, B., Bunkenborg, J., Finnie, C. & Hägglund, Per Mårten, 2 May 2014, In: Journal of Proteome Research. 13, 5, p. 2696-2703 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gibberellic acid-induced aleurone layers responding to heat shock or tunicamycin provide insight into the N-glycoproteome, protein secretion, and endoplasmic reticulum stress
Barba-Espín, G., Dedvisitsakul, P., Hägglund, Per Mårten, Svensson, B. & Finnie, C., 1 Feb 2014, In: Plant Physiology. 164, 2, p. 951-965 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
A novel twist on molecular interactions between thioredoxin and nicotinamide adenine dinucleotide phosphate-dependent thioredoxin reductase: Molecular Interactions Between Trx and NTR
Kirkensgaard, Kristine Groth, Hägglund, Per Mårten, Shahpiri, A., Finnie, C., Henriksen, A. & Svensson, B., 2014, In: Proteins: Structure, Function, and Bioinformatics. 82, 4, p. 607-619Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of thioredoxin target disulfides using isotope-coded affinity tags
Hägglund, Per Mårten, Bunkenborg, J., Maeda, K., Finnie, C. & Svensson, B., 2014, Plant Proteomics. Jorrin-Novo, J. V. (ed.). Humana Press, p. 677-685 9 p. (Methods in Molecular Biology, Vol. 1072).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Lactococcus lactis TrxD represents a subgroup of thioredoxins prevalent in Gram-positive bacteria containing WCXDC active site motifs
Björnberg, O., Efler, P., Ebong, E. D., Svensson, B. & Hägglund, Per Mårten, 2014, In: Archives of Biochemistry and Biophysics. 564, p. 164-172 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of extracellular matrix quality in pulmonary fibrosis
Kristensen, J. H., Karsdal, M. A., Genovese, F., Johnson, S., Svensson, B., Jacobsen, S., Hägglund, Per Mårten & Leeming, D. J., 2014, In: Respiration. 88, 6, p. 487-499 13 p.Research output: Contribution to journal › Review › Research › peer-review
- 2013
- Published
Surface Binding Sites (SBSs), Mechanism and Regulation of Enzymes Degrading Amylopectin and α-Limit Dextrins
S. Møller, M., Cockburn, D., W. Nielsen, J., M. Jensen, J., B. Vester-christensen, M., M. Nielsen, M., M. Andersen, J., Wilkens, C., Rannes, J., Hägglund, Per Mårten, Henriksen, A., Abou Hachem, M., Willemoës, Martin & Svensson, B., 1 Jan 2013, In: Journal of Applied Glycoscience. 60, 2, p. 101-109Research output: Contribution to journal › Review › Research › peer-review
The barley grain thioredoxin system – an update
Hägglund, Per Mårten, Björnberg, O., Navrot, N., Jensen, J. M., Maeda, K., Kirkensgaard, Kristine Groth, Shahpiri, A., Sultan, A., Bunkenborg, J., Gubler, F., Barrero, J. M., Henriksen, A., Finnie, C. & Svensson, B., 2013, In: Frontiers in Plant Science. 4, 5 p., 151.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Dissecting molecular interactions involved in recognition of target disulfides by the barley thioredoxin system
Björnberg, O., Maeda, K., Svensson, B. & Hägglund, Per Mårten, 11 Dec 2012, In: Biochemistry. 51, 49, p. 9930-9939 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivation of barley limit dextrinase inhibitor by thioredoxin-catalysed disulfide reduction
Jensen, J. M., Hägglund, Per Mårten, Christensen, H. E. M. & Svensson, B., 30 Jul 2012, In: FEBS Letters. 586, 16, p. 2479-2482 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of subsite 2 of the Trichoderma reesei β-mannanase TrMan5A in hydrolysis and transglycosylation
Rosengren, A., Hägglund, Per Mårten, Anderson, L., Pavon-Orozco, P., Peterson-Wulff, R., Nerinckx, W. & Stålbrand, H., 1 May 2012, In: Biocatalysis and Biotransformation. 30, 3, p. 338-352 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)
Leeming, D. J., He, Y., Veidal, S. S., Nguyen, Q., Larsen, D. V., Koizumi, M., Segovia-Silvestre, T., Zhang, C., Zheng, Q., Sun, S., Cao, Y., Barkholt, V., Hägglund, Per Mårten, Bay-Jensen, A. C., Qvist, P. & Karsdal, M. A., 1 Nov 2011, In: Biomarkers. 16, 7, p. 616-628 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis
Veidal, S. S., Karsdal, M. A., Nawrocki, A., Larsen, M. R., Dai, Y., Zheng, Q., Hägglund, Per Mårten, Vainer, B., Skjøt-Arkil, H. & Leeming, D. J., 2011, In: Fibrogenesis & Tissue Repair. 4, p. 22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MMP mediated degradation of type VI collagen is highly associated with liver fibrosis--identification and validation of a novel biochemical marker assay
Veidal, S. S., Karsdal, M. A., Vassiliadis, E., Nawrocki, A., Larsen, M. R., Nguyen, Q. H. T., Hägglund, Per Mårten, Luo, Y., Zheng, Q., Vainer, B. & Leeming, D. J., 2011, In: P L o S One. 6, 9, p. e24753Research output: Contribution to journal › Journal article › Research › peer-review
Plant redox proteomics
Navrot, N., Finnie, C., Svensson, B. & Hägglund, Per Mårten, 2011, In: Journal of Proteomics. 74, 8, p. 1450-1462 13 p.Research output: Contribution to journal › Review › Research › peer-review
- 2010
Identification of thioredoxin target disulfides in proteins released from barley aleurone layers
Hägglund, Per Mårten, Bunkenborg, J., Yang, F., Harder, L. M., Finnie, C. & Svensson, B., 2010, In: Journal of Proteomics. 73, 6, p. 1133-1136 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic and thermodynamic properties of two barley thioredoxin h isozymes, HvTrxh1 and HvTrxh2
Maeda, K., Hägglund, Per Mårten, Björnberg, O., Winther, Jakob R. & Svensson, B., 2010, In: FEBS Letters. 584, 15, p. 3376-3380 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
Structure of Hordeum vulgare NADPH-dependent thioredoxin reductase 2. Unwinding the reaction mechanism
Kirkensgaard, Kristine Groth, Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 2009, In: Acta Crystallographica Section D: Biological Crystallography. 65, 9, p. 932-941 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Kinetics and stereochemistry of the Cellulomonas fimi β-mannanase studied using 1 H-NMR
Anderson, L., Hägglund, Per Mårten, Stoll, D., Lo Leggio, Leila, Drakenberg, T. & Stålbrand, H., 1 Jan 2008, In: Biocatalysis and Biotransformation. 26, 1-2, p. 86-95Research output: Contribution to journal › Journal article › Research › peer-review
Crystal structures of barley thioredoxin h isoforms HvTrxh1 and HvTrxh2 reveal features involved in protein recognition and possibly in discriminating the isoform specificity
Maeda, K., Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 2008, In: Protein Science. 17, 6, p. 1015-1024 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of thioredoxin disulfide targets using a quantitative proteomics approach based on isotope-coded affinity tags
Hägglund, Per Mårten, Bunkenborg, J., Maeda, K. & Svensson, B., 2008, In: Journal of Proteome Research. 7, 12, p. 5270-5276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
αAmylases. Interaction with Polysaccharide Substrates, Proteinaceous Inhibitors and Regulatory Proteins
Seo, E. S., Nielsen, M. M., Andersen, J. M., Vester-Christensen, M. B., Jensen, J. M., Christiansen, C., Dilokpimol, A., Hachem, M. A., Hägglund, Per Mårten, Maedal, K., Finnie, C., Blennow, Andreas & Svensson, B., 2008, Carbohydrate-Active Enzymes: Structure, Function and Applications. Elsevier, p. 20-36 17 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2007
- Published
Identification of a trypsin-like serine protease from Trichoderma reesei QM9414
Dienes, D., Börjesson, J., Hägglund, Per Mårten, Tjerneld, F., Lidén, G., Réczey, K. & Stålbrand, H., 3 Apr 2007, In: Enzyme and Microbial Technology. 40, 5, p. 1087-1094 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of glycosylated proteins by mass spectrometry using microcolumns and enzymatic digestion
Hägglund, Per Mårten & Larsen, M. R., 1 Jan 2007, Spectral Techniques In Proteomics. CRC Press, p. 81-100 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Modification-specific proteomic analysis of glycoproteins in human body fluids by mass spectrometry
Bunkenborg, J., Hägglund, Per Mårten & Jensen, O. N., 1 Jan 2007, Proteomics of Human Body Fluids: Principles, Methods, and Applications. Humana Press, p. 107-128 22 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
An enzymatic deglycosylation scheme enabling identification of core fucosylated N-glycans and O-glycosylation site mapping of human plasma proteins
Hägglund, Per Mårten, Matthiesen, R., Elortza, F., Højrup, P., Roepstorff, P., Jensen, O. N. & Bunkenborg, J., 2007, In: Journal of Proteome Research. 6, 8, p. 3021-3031 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Barley peroxidase isozymes: Expression and post-translational modification in mature seeds as identified by two-dimensional gel electrophoresis and mass spectrometry
Laugesen, S., Bak-Jensen, K. S., Hägglund, Per Mårten, Henriksen, A., Finnie, C., Svensson, B. & Roepstorff, P., 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 244-253 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomics of Disulphide and Cysteine Oxidoreduction
Maeda, K., Hägglund, Per Mårten, Finnie, C. & Svensson, B., 2007, Plant Proteomics. Wiley, p. 71-97 27 p. (Annual Plant Reviews, Vol. 28).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2006
- Published
Isolation and characterization of glycosylphosphatidylinositol-anchored peptides by hydrophilic interaction chromatography and MALDI tandem mass spectrometry
Omaetxebarria, M. J., Hägglund, Per Mårten, Elortza, F., Hooper, N. M., Arizmendi, J. M. & Jensen, O. N., 15 May 2006, In: Analytical Chemistry. 78, 10, p. 3335-3341 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Interactions between Barley α-Amylases, Substrates, Inhibitors and Regulatory Proteins
Abou Hachem, M., Bozonnet, S., Willemoës, Martin, C. Bønsager, B., Munch Nielsen, M., Fukuda, K., Kramhøft, B., Maeda, K., Sigurskjold, B. W., Hägglund, Per Mårten, Finnie, C., Mori, H., Robert, X., H. Jensen, M., Tranier, S., Aghajari, N., Haser, R. & Svensson, B., 2006, In: Journal of Applied Glycoscience. 53, 2, p. 163-169Research output: Contribution to journal › Journal article › Research › peer-review
Structural Basis for Target Protein Recognition by the Protein Disulfide Reductase Thioredoxin
Maeda, K., Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 2006, In: Structure. 14, 11, p. 1701-1710 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Molecular characterization of major cat allergen Fel d 1: Expression of heterodimer by use of a baculovirus expression system
Seppälä, U., Hägglund, Per Mårten, Wurtzen, P. A., Ipsen, H., Thorsted, P., Lenhard, T., Roepstorff, P. & Spangfort, M. D., 4 Feb 2005, In: Journal of Biological Chemistry. 280, 5, p. 3208-3216 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural aspects in semicrystalline samples of the mannan II family
Heux, L., Hägglund, Per Mårten, Putaux, J. L. & Chanzy, H., 1 Jan 2005, In: Biomacromolecules. 6, 1, p. 324-332 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Isolation, characterization, and enzymatic hydrolysis of acetyl-galactoglucomannan from spruce (Picea abies)
Stålbrand, H., Lundqvist, J., Andersson, Ann, Hägglund, Per Mårten, Anderson, L., Tjerneld, F., Jacobs, A., Teleman, A., Dahlman, O., Palm, M. & Zacchi, G., 1 Dec 2004, Henicelluloses: Science and Technology. Gatenholm, P. & Tenkanen, M. (eds.). p. 66-78 13 p. (A C S Symposium Series, Vol. 864).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation
Hägglund, Per Mårten, Bunkenborg, J., Elortza, F., Jensen, O. N. & Roepstorff, P., 1 May 2004, In: Journal of Proteome Research. 3, 3, p. 556-566 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
A cellulose-binding module of the Trichoderma reesei β-mannanase Man5A increases the mannan-hydrolysis of complex substrates
Hägglund, Per Mårten, Eriksson, T., Collén, A., Nerinckx, W., Claeyssens, M. & Stålbrand, H., 27 Feb 2003, In: Journal of Biotechnology. 101, 1, p. 37-48 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
endo-β-1,4-Mannanases from blue mussel, Mytilus edulis: Purification, characterization, and mode of action
Xu, B., Hägglund, Per Mårten, Stålbrand, H. & Janson, J. C., 18 Jan 2002, In: Journal of Biotechnology. 92, 3, p. 267-277 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Degradation of mannan I and II crystals by fungal endo-β-1,4-mannanases and a β-1,4-mannosidase studied with transmission electron microscopy
Hägglund, Per Mårten, Sabini, E., Boisset, C., Wilson, K., Chanzy, H. & Stålbrand, H., 4 Oct 2001, In: Biomacromolecules. 2, 3, p. 694-699 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cloning and characterization of Aspergillus niger genes encoding an α-galactosidase and a β-mannosidase involved in galactomannan degradation
Ademark, P., De Vries, R. P., Hägglund, Per Mårten, Stålbrand, H. & Visser, J., 27 Sep 2001, In: European Journal of Biochemistry. 268, 10, p. 2982-2990 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Hydrolytic properties of a β-mannosidase purified from Aspergillus niger
Ademark, P., Lundqvist, J., Hägglund, Per Mårten, Tenkanen, M., Torto, N., Tjerneld, F. & Stålbrand, H., 8 Oct 1999, In: Journal of Biotechnology. 75, 2-3, p. 281-289 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 182565837
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A meta-proteomics approach to study the interspecies interactions affecting microbial biofilm development in a model community
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The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage
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Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
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