Paul Cloos
Paul Cloos

Associate Professor


  1. 2018
  2. Published

    The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

    Weissmann, S., Cloos, Paul, Sidoli, S., Jensen, O. N., Pollard, S. & Helin, Kristian, 2018, In : Cancer Research. 78, 15, p. 4114-4125 12 p.

    Research output: Contribution to journalJournal article

  3. 2014
  4. Published
  5. 2013
  6. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, Brian, Helgstrand, C., Andersson, J. L., Leurs, Ulrike, Cloos, Paul, Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In : P L o S One. 8, 7, p. e67653

    Research output: Contribution to journalJournal article

  7. 2012
  8. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, Paul, Kastrup, Jette Sandholm Jensen, Helin, Kristian, Olsen, L. & Gajhede, Michael, Jun 2012, In : F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal article

  9. Published

    Identification of catechols as histone-lysine demethylase inhibitors

    Nielsen, A. L., Kristensen, L. H., Stephansen, K. B., Kristensen, J. B. L., Helgstrand, C., Lees, M., Cloos, Paul, Helin, Kristian, Gajhede, Michael & Olsen, L., 2012, In : F E B S Letters. 586, 8, p. 1190-4 5 p.

    Research output: Contribution to journalJournal article

  10. 2011
  11. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal article

  12. Published

    TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

    Williams, Kristine, Christensen, Jesper, Pedersen, Marianne Terndrup, Johansen, Jens Vilstrup, Cloos, Paul, Rappsilber, J. & Helin, Kristian, 19 May 2011, In : Nature. 473, 7347, p. 343-8 6 p.

    Research output: Contribution to journalJournal article

  13. Published

    The Role of Histone Demethylases in Disease

    Cloos, Paul, 2011, Epigenetic Aspects of Chronic Diseases. Roach, HI., Bronner, F. & Oreffo, ROC. (eds.). Springer, p. 75-93 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  14. 2010
  15. Published

    JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

    Pasini, D., Cloos, Paul, Walfridsson, J., Pålsson, Linda Elin, Bukowski, J., Johansen, Jens Vilstrup, Bak, Mads, Tommerup, Niels, Rappsilber, J. & Helin, Kristian, 2010, In : Nature. 464, 7286, p. 306-10 4 p.

    Research output: Contribution to journalJournal article

  16. 2009
  17. Published

    The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

    Agger, Karl, Cloos, Paul, Rudkjaer, L., Williams, Kristine, Andersen, G., Christensen, Jesper & Helin, Kristian, 2009, In : Genes & Development. 23, 10, p. 1171-6 5 p.

    Research output: Contribution to journalJournal article

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