Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor


  1. 2024
  2. Accepted/In press

    AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications

    Pippione, A. C., Vigato, C., Tucciarello, C., Hussain, Samrina, Salladini, Edoardo, Truong, H. H., Henriksen, N. M., Vanzetti, G., Giordano, G., Zonari, D., Mirza, Osman Asghar, Frydenvang, Karla Andrea, Pignochino, Y., Oliaro-Bosso, S., Boschi, D. & Lolli, M. L., 2024, (Accepted/In press) In: ACS Medicinal Chemistry Letters.

    Research output: Contribution to journalLetterResearchpeer-review

  3. Published

    Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer

    Pippione, A. C., Kovachka, S., Vigato, C., Bertarini, L., Mannella, I., Sainas, S., Rolando, B., Denasio, E., Piercy-Mycock, H., Romalho, L., Salladini, E., Adinolfi, S., Zonari, D., Peraldo-Neia, C., Chiorino, G., Passoni, A., Mirza, O. A., Frydenvang, K., Pors, K., Lolli, M. L. & 3 others, Spyrakis, F., Oliaro-Bosso, S. & Boschi, D., 2024, In: European Journal of Medicinal Chemistry. 268, 20 p., 116193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Published

    Functional Characterization of the Putative POT from Clostridium perfringens

    Gharabli, H., Rafiq, M., Iqbal, A., Yan, R., Aduri, N. G., Sharma, N., Prabhala, B. K. & Mirza, Osman Asghar, 2023, In: Biology. 12, 5, 11 p., 651.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Accepted/In press

    Identification of additional mechanistically important residues in the multidrug transporter styMdtM of Salmonella Typhi

    Shaheen, A., Tariq, A., Ismat, F., Naveed, H., De Zorzi, R., Iqbal, M., Storici, P., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2023, (Accepted/In press) In: Journal of Biomolecular Structure and Dynamics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification of key amino acid residues in AtUMAMIT29 for transport of glucosinolates

    Meyer, L., Crocoll, C., Halkier, Barbara Ann, Mirza, Osman Asghar & Xu, Deyang, 2023, In: Frontiers in Plant Science. 14, 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

    Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

    Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Accepted/In press

    The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

    Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. 2022
  12. Published

    Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1

    Rafiq, M., Ernst, H. A., Aduri, N. G., Prabhala, B. K., Tufail, S., Rahman, M., Bloch, Magnus Borup, Mirza, N., Taylor, Nicholas M I, Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2022, In: Protein Expression and Purification. 190, 7 p., 105990.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Highly soluble and stable ‘insertion domain’ of the capsid penton base protein provides complete protection against infections caused by fowl adenoviruses

    Tufail, S., Shah, M. A., Asif, T. A., Ullah, R., Shehzad, A., Ismat, F., Shah, M. S., Habib, M., Calisto, B. M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2022, In: Microbial Pathogenesis. 173, Part A, 6 p., 105835.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 1302772