Ole Winther

Ole Winther

Professor with special responsibilities, Visiting professor, Professor MSO


  1. 2020
  2. Published

    Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

    Prachar, Marek, Justesen, S., Steen-Jensen, D. B., Thorgrimsen, S., Jurgons, E., Winther, Ole & Bagger, F. O., 2020, In: Scientific Reports. 10, 8 p., 20465.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Optimal Variance Control of the Score-Function Gradient Estimator for Importance Weighted Bounds

    Liévin, V., Dittadi, A., Christensen, Anders & Winther, Ole, 2020, In: Advances in Neural Information Processing Systems. 2020-December, 12 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  4. Published

    Systematic review of machine learning for diagnosis and prognosis in dermatology

    Thomsen, K., Iversen, L., Titlestad, T. L. & Winther, Ole, 2020, In: Journal of Dermatological Treatment. 31, 5, p. 496-510

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    scVAE: variational auto-encoders for single-cell gene expression data

    Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Forecasting Mood in Bipolar Disorder From Smartphone Self-assessments: Hierarchical Bayesian Approach

    Busk, J., Faurholt-Jepsen, M., Frost, M., Bardram, J. E., Kessing, Lars Vedel & Winther, Ole, 1 Apr 2020, In: JMIR mHealth and uHealth. 8, 4, 14 p., e15028.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2021
  8. Published

    A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

    Gabrielaite, M., Torp, M., Rasmussen, M., Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C., Kinalis, S., Madsen, M., Yde, C., Rønn, O. L., Marvig, R., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, bioRxiv, 29 p.

    Research output: Working paperPreprintResearch

  9. Published

    A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

    Gabrielaite, M., Torp, M. H., Rasmussen, Malthe Sebro, Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, In: Cancers. 13, 24, 6283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Improved metagenome binning and assembly using deep variational autoencoders

    Nissen, J. N., Johansen, Joachim, Allesoe, R. L., Sonderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Jensen, Lars Juhl, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2021, In: Nature Biotechnology. 39, p. 555-560

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data

    Montemurro, A., Schuster, Viktoria, Povlsen, H. R., Bentzen, A. K., Jurtz, V., Chronister, W. D., Crinklaw, A., Hadrup, S. R., Winther, Ole, Peters, B., Jessen, L. E. & Nielsen, M., 2021, In: Communications Biology . 4, 13 p., 1060.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Reducing the rate of psychiatric re-admissions in bipolar disorder using smartphones - The RADMIS trial

    Faurholt-Jepsen, M., Lindbjerg Tønning, M., Fros, M., Martiny, Klaus, Tuxen, N., Rosenberg, N., Busk, J., Winther, Ole, Thaysen-Petersen, D., Aamund, K. A., Tolderlund, L., Bardram, J. E. & Kessing, Lars Vedel, 2021, In: Acta Psychiatrica Scandinavica. 143, 5, p. 453-465 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The effect of smartphone-based monitoring and treatment on the rate and duration of psychiatric readmission in patients with unipolar depressive disorder: The RADMIS randomized controlled trial

    Tønning, M. L., Faurholt-Jepsen, Maria , Frost, M., Martiny, Klaus, Tuxen, N., Rosenberg, N., Busk, J., Winther, Ole, Melbye, S. A., Thaysen-Petersen, D., Aamund, K. A., Tolderlundh, L., Bardram, J. E. & Kessing, Lars Vedel, 2021, In: Journal of Affective Disorders. 282, p. 354-363 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2022
  15. Published

    Calibrated uncertainty for molecular property prediction using ensembles of message passing neural networks

    Busk, J., Jørgensen, P. B., Bhowmik, A., Schmidt, M. N., Winther, Ole & Vegge, T., 2022, In: Machine Learning: Science and Technology. 3, 1, 12 p., 015012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    DeepLoc 2.0: multi-label subcellular localization prediction using protein language models

    Thumuluri, V., Almagro Armenteros, J. J., Johansen, A. R., Nielsen, H. & Winther, Ole, 2022, In: Nucleic Acids Research. 50, W1, p. W228-W234

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Interpretable autoencoders trained on single cell sequencing data can transfer directly to data from unseen tissues

    Walbech, J. S., Kinalis, S., Winther, Ole, Nielsen, Finn Cilius & Bagger, F. O., 2022, In: Cells. 11, 12 p., 85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    NetSurfP-3.0: accurate and fast prediction of protein structural features by protein language models and deep learning

    Høie, M. H., Kiehl, E. N., Petersen, Bent, Nielsen, M., Winther, Ole, Nielsen, H., Hallgren, J. & Marcatili, P., 2022, In: Nucleic Acids Research. 50, W1, p. W510-W515 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    SignalP 6.0 predicts all five types of signal peptides using protein language models

    Teufel, Felix Georg, Almagro Armenteros, J. J., Johansen, A. R., Gíslason, M. H., Pihl, S. I., Tsirigos, Konstantinos, Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 2022, In: Nature Biotechnology. 40, p. 1023-1025

    Research output: Contribution to journalComment/debateResearch

  20. Published

    Transfer learning reveals sequence determinants of regulatory element accessibility

    Salvatore, Marco, Horlacher, M., Winther, Ole & Andersson, Robin, 2022, bioRxiv, 24 p.

    Research output: Working paperPreprintResearch

  21. Published

    Transition1x: a dataset for building generalizable reactive machine learning potentials

    Schreiner, M., Bhowmik, A., Vegge, T., Busk, J. & Winther, Ole, 2022, In: Scientific Data. 9, 1, 9 p., 779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2023
  23. Published

    Deep integrative models for large-scale human genomics

    Sigurdsson, Arnór Ingi, Louloudis, Ioannis, Banasik, Karina, Westergaard, David, Winther, Ole, Lund, O., Ostrowski, Sisse Rye, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, B. & Rasmussen, Simon, 2023, In: Nucleic Acids Symposium Series. 51, 12, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    DeepPeptide predicts cleaved peptides in proteins using conditional random fields

    Teufel, Felix Georg, Refsgaard, J. C., Madsen, C. T., Stahlhut, C., Grønborg, M., Winther, Ole & Madsen, D., 2023, In: Bioinformatics (Oxford, England). 39, 10, 6 p., btad616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Deorphanizing Peptides Using Structure Prediction

    Teufel, Felix Georg, Refsgaard, J. C., Kasimova, M. A., Deibler, K., Madsen, C. T., Stahlhut, C., Grønborg, M., Winther, Ole & Madsen, D., 2023, In: Journal of Chemical Information and Modeling. 63, 9, 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    DermX: An end-to-end framework for explainable automated dermatological diagnosis

    Jalaboi, R., Faye, F., Orbes-Arteaga, M., Jørgensen, D., Winther, Ole & Galimzianova, A., 2023, In: Medical Image Analysis. 83, 12 p., 102647.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Explainable Image Quality Assessments in Teledermatological Photography

    Jalaboi, R., Winther, Ole & Galimzianova, A., 2023, In: Telemedicine and e-Health. 29, 9, p. 1342-1348 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Graph neural network interatomic potential ensembles with calibrated aleatoric and epistemic uncertainty on energy and forces

    Busk, J., Schmidt, M. N., Winther, Ole, Vegge, T. & Jørgensen, P. B., 2023, In: Physical Chemistry Chemical Physics. 25, p. 25828-25837 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    GraphPart: homology partitioning for biological sequence analysis

    Teufel, Felix Georg, Gíslason, M. H., Almagro Armenteros, J. J., Johansen, A. R., Winther, Ole & Nielsen, H., 2023, In: NAR Genomics and Bioinformatics. 5, 4, 9 p., lqad088.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Molecular Representations in Machine-Learning-Based Prediction of PK Parameters for Insulin Analogs

    Einarson, K. A., Bendtsen, K. M., Li, K., Thomsen, M., Kristensen, N. R., Winther, Ole, Fulle, S., Clemmensen, L. & Refsgaard, H. H. F., 2023, In: ACS Omega. 8, 26, p. 23566-23578 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    RNA trafficking and subcellular localization—a review of mechanisms, experimental and predictive methodologies

    Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2023, In: Briefings in Bioinformatics. 24, 5, 14 p., bbad249.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Towards in silico CLIP-seq: predicting protein-RNA interaction via sequence-to-signal learning

    Horlacher, M., Wagner, N., Moyon, L., Kuret, K., Goedert, N., Salvatore, Marco, Ule, J., Gagneur, J., Winther, Ole & Marsico, A., 2023, In: Genome Biology. 24, 1, 37 p., 180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Transfer learning identifies sequence determinants of cell-type specific regulatory element accessibility

    Salvatore, Marco, Horlacher, M., Marsico, A., Winther, Ole & Andersson, Robin, 2023, In: NAR Genomics and Bioinformatics. 5, 2, 10 p., 026.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Uncertainty-aware and explainable machine learning for early prediction of battery degradation trajectory

    Rieger, L. H., Flores, E., Nielsen, K. F., Norby, P., Ayerbe, E., Winther, Ole, Vegge, T. & Bhowmik, A., 2023, In: Digital Discovery. 2, 1, p. 112-122 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Variational Open-Domain Question Answering

    Liévin, V., Motzfeldt, A. G., Jensen, I. R. & Winther, Ole, 2023, In: Proceedings of Machine Learning Research. 202, p. 20950-20977 28 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  36. 2024
  37. Published

    Can large language models reason about medical questions?

    Liévin, V., Hother, C. E., Motzfeldt, A. G. & Winther, Ole, 2024, In: Patterns. 5, 3, 12 p., 100943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    DeepLocRNA: an interpretable deep learning model for predicting RNA subcellular localization with domain-specific transfer-learning

    Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2024, In: Bioinformatics. 40, 2, 10 p., btae065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    DiscoTope-3.0: improved B-cell epitope prediction using inverse folding latent representations

    Høie, M. H., Gade, F. S., Johansen, J., Würtzen, C., Winther, Ole, Nielsen, M. & Marcatili, P., 2024, In: Frontiers in Immunology. 15, 12 p., 1322712.

    Research output: Contribution to journalJournal articleResearchpeer-review

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