Ole Østergaard

Ole Østergaard

Researcher, Forsker

Member of:


    1. 2024
    2. Published
    3. Published

      Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

      Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T. & 31 others, Sahoo, S., Torrecilhas, A. C., Zheng, L., Zijlstra, A., Abuelreich, S., Bagabas, R., Bergese, P., Bridges, E. M., Brucale, M., Burger, D., Carney, R. P., Cocucci, E., Crescitelli, R., Hanser, E., Harris, A. L., Haughey, N. J., Benediktsdóttir, B. E., Gargiulo, E., Gori, A., Guo, W., Hufnagel, Antonia Sophie, Di Ianni, E., Jacobsen, Søren, Li, B., Mellergaard, M., Nejsum, P., Nolan, J. P., Østergaard, Ole, Yarani, R., Yin, H. & MISEV Consortium, M. C., 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.

      Research output: Contribution to journalJournal articlepeer-review

    4. E-pub ahead of print

      Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition

      Guzman, U. H., Martinez Del Val, A., Ye, Z., Damoc, E., Arrey, T. N., Pashkova, A., Renuse, S., Denisov, E., Petzoldt, J., Peterson, A. C., Harking, F., Østergaard, O., Rydbirk, R., Aznar, S., Stewart, H., Xuan, Y., Hermanson, D., Horning, S., Hock, C., Makarov, A. & 2 others, Zabrouskov, V. & Olsen, Jesper Velgaard, 2024, (E-pub ahead of print) In: Nature Biotechnology.

      Research output: Contribution to journalJournal articlepeer-review

    5. 2023
    6. Published
    7. 2022
    8. Published

      Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology

      Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, Aznar, S., 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.

      Research output: Contribution to journalJournal articlepeer-review

    9. 2021
    10. Published

      Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

      Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.

      Research output: Contribution to journalJournal articlepeer-review

    11. 2020
    12. Published

      Mass-Spectrometry Based Proteome Comparison of Extracellular Vesicle Isolation Methods: Comparison of ME-kit, Size-Exclusion Chromatography, and High-Speed Centrifugation

      Askeland, A., Borup, A., Østergaard, Ole, Olsen, Jesper Velgaard, Lund, S. M., Christiansen, G., Kristensen, S. R., Heegaard, N. H. H. & Pedersen, S., 2020, In: Biomedicines. 8, 8, 15 p., 246.

      Research output: Contribution to journalJournal articlepeer-review

    13. 2018
    14. Generation and Characterization of Cell-Derived Microvesicles from HUVECs

      Cherre, S., Granberg, M., Østergaard, Ole, Heegaard, N. H. H. & Rozlosnik, N., 2018, In: BioNanoScience. 8, p. 140–153 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    15. Published

      Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

      Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J-M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M., Beckham, C. & 31 others, Bedina Zavec, A., Benmoussa, A., Berardi, A. C., Bergese, P., Bielska, E., Blenkiron, C., Bobis-Wozowicz, S., Boilard, E., Boireau, W., Bongiovanni, A., Borràs, F. E., Bosch, S., Boulanger, C. M., Breakefield, X., Breglio, A. M., Brennan, M. Á., Brigstock, D. R., Brisson, A., Broekman, M. L., Bromberg, J. F., Bryl-Górecka, P., Buch, S., Buck, A. H., Burger, D., Busatto, S., Buschmann, D., Jørgensen, M. M., Jacobsen, Søren, Nejsum, P., Østergaard, Ole & Xu, J., 2018, In: Journal of Extracellular Vesicles. 7, 1, p. 1-47 1535750.

      Research output: Contribution to journalJournal articlepeer-review

    16. 2017
    17. Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions

      Loke, I., Østergaard, Ole, Heegaard, N. H. H., Packer, N. H. & Thaysen-Andersen, M., Aug 2017, In: Molecular and Cellular Proteomics. 16, 8, p. 1507-1527 21 p.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      A review of studies of the proteomes of circulating microparticles: Key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus

      Nielsen, C. T., Østergaard, Ole, Rasmussen, N. S., Jacobsen, Søren & Heegaard, N. H. H., 2017, In: Clinical Proteomics. 14, 24 p., 11.

      Research output: Contribution to journalReviewpeer-review

    19. Published

      Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines

      Alsarraf, H., Dedic, E., Bjerrum, Morten Jannik, Østergaard, Ole, Kristensen, M. P., Petersen, J. W. & Jørgensen, R., 2017, In: Virulence. 8, 8, p. 1880-1889 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    20. Published

      Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus

      Østergaard, Ole, Nielsen, Christoffer Tandrup Holst, Tanassi, J. T., Iversen, L. V., Jacobsen, Søren & Heegaard, N. H. H., 2017, In: Clinical Proteomics. 14, 13 p., 23.

      Research output: Contribution to journalJournal articlepeer-review

    21. 2016
    22. A Novel Fic (Filamentation Induced by cAMP) Protein from Clostridium difficile Reveals an Inhibitory Motif-independent Adenylylation/AMPylation Mechanism

      Dedic, E., Alsarraf, H., Welner, D. H., Østergaard, Ole, Klychnikov, O. I., Hensbergen, P. J., Corver, J., van Leeuwen, H. C. & Jørgensen, R., 2016, In: The Journal of Biological Chemistry. 291, 25, p. 13286-13300 15 p.

      Research output: Contribution to journalJournal articlepeer-review

    23. Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation

      Østergaard, Ole, Follmann, F., Olsen, A. W., Heegaard, N. H., Andersen, P. & Rosenkrands, I., 2016, In: Molecular and Cellular Proteomics. 15, 12, p. 3540-3550 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    24. 2015
    25. Published

      Impact of microRNA-130a on the neutrophil proteome

      Pedersen, C. C., Refsgaard, J. C., Østergaard, Ole, Jensen, Lars Juhl, Heegaard, N. H. H., Borregaard, N. & Cowland, J. B., 25 Nov 2015, In: B M C Immunology. 16, 10 p., 70.

      Research output: Contribution to journalJournal articlepeer-review

    26. Published

      Cross-sectional study of soluble selectins, fractions of circulating microparticles and their relationship to lung and skin involvement in systemic sclerosis

      Iversen, L. V., Ullman, S., Østergaard, Ole, Nielsen, C. T., Halberg, P., Karlsmark, Tonny, Heegaard, N. H. H. & Jacobsen, Søren, 2015, In: BMC Musculoskeletal Disorders. 16, 9 p., 191.

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis

      Nielsen, Christoffer Tandrup Holst, Østergaard, Ole, Rekvig, O. P., Sturfelt, G., Jacobsen, Søren & Heegaard, N. H. H., 2015, In: Lupus. 24, 11, p. 1150-60

      Research output: Contribution to journalJournal articlepeer-review

    28. Important options available--from start to finish--for translating proteomics results to clinical chemistry

      Heegaard, N. H. H., Østergaard, Ole, Bahl, J. M. C., Overgaard, M., Beck, H. C., Rasmussen, L. M. & Larsen, M. R., 2015, In: Proteomics - Clinical Applications. 9, 1-2, p. 235-252 18 p.

      Research output: Contribution to journalReviewpeer-review

    29. 2014
    30. Published

      Filaggrin is a predominant member of the denaturation-resistant nickel-binding proteome of human epidermis

      Ross-Hansen, K., Østergaard, Ole, Tanassi, J. T., Thyssen, Jacob Pontoppidan, Johansen, Jeanne Duus, Menné, T. & Heegaard, N. H. H., Apr 2014, In: The Journal of Investigative Dermatology. 134, 4, p. 1164-1166 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    31. Published

      Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses

      Sørensen, O. E., Clemmensen, S. N., Dahl, S. L., Østergaard, Ole, Heegaard, N. H. H., Glenthøj, A., Nielsen, Finn Cilius & Borregaard, N., 2014, In: The Journal of Clinical Investigation. 124, 10, p. 4539-48 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      Plasma levels of galectin-3-binding protein reflect type I interferon activity and are increased in patients with systemic lupus erythematosus

      Nielsen, C. T., Lood, C., Østergaard, Ole, Iversen, L. V., Voss, A., Bengtsson, A., Jacobsen, Søren & Heegaard, N. H. H., 2014, In: Lupus Now. 1, p. 1-8 8 p., e000026.

      Research output: Contribution to journalJournal articlepeer-review

    33. Published

      Protein expression, characterization, crystallization and preliminary X-ray crystallographic analysis of a Fic protein from Clostridium difficile

      Welner, D., Dedic, E., van Leeuwen, H. C., Kuijper, E., Bjerrum, Morten Jannik, Østergaard, Ole & Jørgensen, R., 2014, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 70, p. 827-831 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    34. 2013
    35. Published

      A heparin-based method for flow cytometric analysis of microparticles directly from platelet-poor plasma in calcium containing buffer

      Iversen, L. V., Østergaard, Ole, Nielsen, C., Jacobsen, Søren & Heegaard, N. H. H., 2013, In: Journal of Immunological Methods. 388, 1-2, p. 49-59 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    36. Published

      Circulating microparticles and plasma levels of soluble E- and P-selectins in patients with systemic sclerosis

      Iversen, L., Østergaard, Ole, Ullman, S., Nielsen, C. T., Halberg, P., Karlsmark, Tonny, Heegaard, N. H. H. & Jacobsen, Søren, 2013, In: Scandinavian Journal of Rheumatology. 42, 6, p. 473-482 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    37. Published

      Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors

      Rørvig, S., Østergaard, Ole, Heegaard, N. H. H. & Borregaard, N., 2013, In: Journal of Leukocyte Biology. 94, 4, p. 711-721 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    38. Published

      Unique Protein Signature of Circulating Microparticles in Systemic Lupus Erythematosus

      Østergaard, Ole, Nielsen, C., Iversen, L. V., Tanassi, J. T., Knudsen, S., Jacobsen, Søren & Heegaard, N. H. H., 2013, In: Arthritis & Rheumatism. 65, 10, p. 2680-2690 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    39. 2012
    40. Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation

      Nielsen, C. T., Østergaard, Ole, Stener, L., Iversen, L. V., Truedsson, L., Gullstrand, B., Jacobsen, Søren & Heegaard, N. H. H., 2012, In: Arthritis & Rheumatism. 64, 4, p. 1227-1236 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    41. Published

      Quantitative proteome profiling of normal human circulating microparticles

      Østergaard, Ole, Nielsen, C. T., Iversen, L. V., Jacobsen, Søren, Tanassi, J. T. & Heegaard, N. H. H., 2012, In: Journal of Proteome Research. 11, 4, p. 2154-63 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    42. 2011
    43. Published

      Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis

      Clemmensen, S. N., Jacobsen, L. C., Rørvig, S., Askaa, B., Christenson, K., Iversen, M., Jørgensen, M. H., Larsen, M. T., van Deurs, B., Østergaard, Ole, Heegaard, N. H., Cowland, J. B. & Borregaard, N., 1 Jun 2011, In: European Journal of Haematology. 86, 6, p. 517-30 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    44. Published

      Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus

      Nielsen, C. T., Østergaard, Ole, Johnsen, C., Jacobsen, Søren & Heegaard, N. H. H., 2011, In: Arthritis & Rheumatism. 63, 10, p. 3067-77 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    45. 2009
    46. Published

      Integration of the barley genetic and seed proteome maps for chromosome 1H, 2H, 3H, 5H and 7H

      Finnie, C., Bagge, M., Steenholdt, T., Østergaard, Ole, Bak-Jensen, K. S., Backes, G. M., Jensen, A., Giese, N. H., Larsen, J., Roepstorff, P. & Svensson, B., 2009, In: Functional & Integrative Genomics. 9, 1, p. 135-143 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    47. 2007
    48. Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis

      Giorgetti, S., Stoppini, M., Tennent, G. A., Relini, A., Marchese, L., Raimondi, S., Monti, M., Marini, S., Østergaard, Ole, Heegaard, N. H. H., Pucci, P., Esposito, G., Merlini, G. & Bellotti, V., 2007, In: Protein Science. 16, 2, p. 343-9 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    49. Spatio-temporal profiling and degradation of alpha-amylase isozymes during barley seed germination

      Bak-Jensen, K. S., Laugesen, S., Østergaard, Ole, Finnie, C., Roepstorff, P. & Svensson, B., 2007, In: F E B S Journal. 274, 10, p. 2552-2565 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    50. 2004
    51. Aspects of the barley seed proteome during development and germination

      Finnie, C., Maeda, K., Østergaard, Ole, Bak-Jensen, K. S., Larsen, J. & Svensson, B., 2004, In: Biochemical Society Transactions. 32, Pt3, p. 517-9 3 p.

      Research output: Contribution to journalReviewpeer-review

    52. Proteome analysis of barley seeds: Identification of major proteins from two-dimensional gels (pI 4-7)

      Østergaard, Ole, Finnie, C., Laugesen, S., Roepstorff, P. & Svensson, B., 2004, In: Proteomics. 4, 8, p. 2437-2447 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    53. 2003
    54. Identification, cloning and characterization of two thioredoxin h isoforms, HvTrxh1 and HvTrxh2, from the barley seed proteome

      Maeda, K., Finnie, C., Østergaard, Ole & Svensson, B., 2003, In: European Journal of Biochemistry. 270, 12, p. 2633-43 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    55. 2002
    56. Initial proteome analysis of mature barley seeds and malt

      Østergaard, Ole, Melchior, S., Roepstorff, P. & Svensson, B., 2002, In: Proteomics. 2, 6, p. 733-9 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    ID: 196983073