Ole Jannik Bjerrum

Ole Jannik Bjerrum

Professor, emeritus


  1. 2022
  2. Published

    Dorsal horn volume loss and pain pathway changes in Cavalier King Charles Spaniels with syringomyelia, signs of pain, and phantom scratching

    Mortensen, D., Thoefner, M. S., Agerholm, Jørgen Steen, Slumstrup, L., Jensen, T. S., Bjerrum, Ole Jannik, Berendt, Mette & Nyengaard, J. R., 2022, In: Pain. 163, 12, p. 2365-2379

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2020
  4. Published

    Analysis of the Authorized Target Populations for Fixed Dose Combination Products Between 2000 and 2017 Reveals Discrepancies Between EMA's and FDA's Views on Initial Dual-Therapy

    Bjerrum, Ole Jannik, Eichendorff, S. & Alkis, N. B., Mar 2020, In: Therapeutic Innovation & Regulatory Science. 54, 2, p. 297-302 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

    Nøhr-Nielsen, A., Lange, Theis, Forman, Julie Lyng, Papathanasiou, T., Foster, D. J. R., Upton, R. N., Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2020, In: The AAPS Journal. 22, 2, 32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pregabalin alleviates clinical signs of syringomyelia-related central neuropathic pain in Cavalier King Charles Spaniel dogs: a randomized controlled trial

    Thoefner, M. S., Skovgaard, Lene Theil, McEvoy, Fintan, Berendt, Mette & Bjerrum, Ole Jannik, 2020, In: Veterinary Anaesthesia and Analgesia. 47, 2, p. 238–248

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2019
  8. Published

    Analysis of the Authorized Target Populations for Fixed Dose Combination Products Between 2000 and 2017 Reveals Discrepancies Between EMA’s and FDA’s Views on Initial Dual-Therapy

    Bjerrum, Ole Jannik, Eichendorff, S. & Alkis, N. B., 2019, In: Therapeutic Innovation & Regulatory Science. 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

    Nøhr-Nielsen, A., De Bruin, M. L., Thomsen, M., Pipper, C. B., Lange, Theis, Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2019, In: British Journal of Clinical Pharmacology. 85, 8, p. 1829-1840 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Glutamate transport system as a key constituent of glutamosome: Molecular pathology and pharmacological modulation in chronic pain

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2019, In: Neuropharmacology. 161, 107623.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Mechanical sensory threshold in Cavalier King Charles spaniels with syringomyelia-associated scratching and control dogs

    Thoefner, M. S., Westrup, U., Toft, N., Bjerrum, Ole Jannik & Berendt, Mette, 2019, In: Veterinary Journal. 246, p. 92-97 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Identifying Off-label Prescriptions trough Data Mining in Danish Community Pharmacy Servers: An exploratory Study on Desmopressin, Diclofenac, Fucidin, Mirtazapine and Quetiapine

    Bjerrum, Ole Jannik & Androlyte, M., Aug 2018, In: Basic & Clinical Pharmacology & Toxicology. 123 , 2, p. 155–160 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain

    Kristensen, P. J., Gegelashvili, G., Munro, G., Heegaard, Anne-Marie & Bjerrum, Ole Jannik, Feb 2018, In: European Journal of Pain. 22, 2, p. 282-294

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

    Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2017
  18. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

    Kristensen, P. J., Heegaard, Anne-Marie, Hestehave, Sara, Jeggo, R. D., Bjerrum, Ole Jannik & Munro, G., Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    From Face-to-fase training to blended learning in the postgraduate program SafeSciMet - a case study

    Bjerrum, Ole Jannik, Vos, C., Dragovic, S., Jochimsen, M., Dirac, J., Foth, H. & Wiese, J., 2017, In: European Journal of Pharmaceutical Sciences. 96, p. III-VIII 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain: Molecular Mechanisms and Pharmacology

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 225-253 29 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  21. 2016
  22. Published

    A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science: Workshop Proceedings and Commentary

    Borup, G., Bach, K. F., Schmiegelow, M., Kildemoes, H. W., Bjerrum, Ole Jannik & Westergaard, N., May 2016, In: Therapeutic Innovation & Regulatory Science. 50, 3, p. 304-311 8 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  23. 2015
  24. Published

    An analysis of the fixed-dose combinations authorized by the European Union, 2009-14: A Focus on benefit-risk and clinial development condition

    Sawicki-Wrzask, D., Thomsen, M. & Bjerrum, Ole Jannik, 2015, In: Therapeutic Innovation & Regulatory Science. 49, 4, p. 553-559 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    High-affinity Glutamate Transporters in Pain: An Emerging and Therapeutic Target

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2015, In: Journal of Neurochemistry. 6, p. 712-30 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Intraplantar injection of tetrahydrobiopterin induces nociception in mice

    Nasser, A., Ali, S., Wilsbech, S., Bjerrum, Ole Jannik & Birk Møller, L., 2015, In: Neuroscience Letters. 584, p. 247-252 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The wider use of fixed-dose combinations emphasizes the need for a global approach to regulatory guideline development

    Gautam, Y., Bjerrum, Ole Jannik & Schmiegelow, M., 2015, In: Therapeutic Innovation & Regulatory Science. 49, 1, p. 197-204 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2014
  29. Published

    Drug-drug combinations revisited

    Bjerrum, Ole Jannik, Gautam, Y., Honoré, P. G. H. & Vana, V., 15 Jan 2014, In: European Journal of Hospital Pharmacy - Science and Practice. 21, 1, p. 8-12 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. 2013
  31. Published

    Measurement of sedation in rats. Comparison of the locomotor activity test, open field test and the rotarod test

    Bjerrum, Ole Jannik, Nasser, A., Basnet, A., Merry, A. & Kristensen, P., Nov 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  32. Published

    Medicines combinations options and regulatory hurdles

    Bjerrum, Ole Jannik, Gautam, Y., Bjerrum, E. J., Schmiegelow, M. & Boonen, H. C. M., 16 Jul 2013, In: European Journal of Pharmaceutical Sciences. 49, 4, p. 659-63 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie, Møller, A. T., Larsen, M., Dalbøge, L. S., Dupont, E., Jensen, T. S. & Møller, L. B., 19 Feb 2013, In: Molecular Pain. 9, p. 5

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Donepezil anvendt ved neuropatisk smerte

    Bjerrum, Ole Jannik & Bjerrum, H. J., 2013, In: Ugesskrift for læger. 175, 42, p. 2493-2494 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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