Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology


  1. 2017
  2. Published

    Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study

    Bojesen, R. D., Riis, Lene Buhl, Høgdall, Estrid Vilma Solyom, Nielsen, Ole Haagen & Jess, T., Dec 2017, In: Clinical Gastroenterology and Hepatology. 15, 12, p. 1900-1907.e2

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis

    Soendergaard, C., Kvist, P. H., Thygesen, P., Reslow, M., Nielsen, Ole Haagen, Kopchick, J. J. & Holm, T. L., 23 Sep 2017, In: International Journal of Molecular Sciences (Online). 18, 10, 20 p., 2046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A proposal for a study on treatment selection and lifestyle recommendations in chronic inflammatory diseases: A danish multidisciplinary collaboration on prognostic factors and personalised medicine

    Andersen, V., Holmskov, U., Bek Sørensen, S., Jawhara, M., Andersen, K. W., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F., Nielsen, O. H. & 18 others, Christensen, R., Bo Bojesen, A., Sorensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Heitmann, Berit, Boye, M., Nielsen, C. L., Werner, L., Kjeldsen, J. & Ellingsen, T., May 2017, In: Nutrients. 9, 5, 16 p., 499.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    An open prospective study evaluating efficacy and safety of a new medical device for rectal application of activated carbon in the treatment of chronic, uncomplicated perianal fistulas

    Zawadzki, A., Johnson, L. B., Bohe, M., Johansson, C., Ekelund, M. & Nielsen, Ole Haagen, Apr 2017, In: International Journal of Colorectal Disease. 32, 4, p. 509-512 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Sphingosine-1-phosphate signaling in inflammatory bowel disease

    Nielsen, Ole Haagen, Li, Yuan, Lindbom, B. J. & Coskun, M., Apr 2017, In: Trends in Molecular Medicine. 23, 4, p. 362-374 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Novel targeted therapies for inflammatory bowel disease

    Coskun, M., Vermeire, S. & Nielsen, Ole Haagen, Feb 2017, In: Trends in Pharmacological Sciences. 38, 2, p. 127-142 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

    Holmberg, F. E., Seidelin, Jakob Benedict, Yin, X., Mead, B. E., Tong, Z., Li, Yuan, Karp, J. M. & Nielsen, Ole Haagen, 2017, In: EMBO Molecular Medicine. 9, 5, p. 558-570 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    How genetic testing can lead to targeted management of XIAP deficiency-related inflammatory bowel disease

    Nielsen, Ole Haagen & LaCasse, E. C., 2017, In: Genetics In Medicine. 19, p. 133-143

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Impact of feedback and monitoring on colonoscopy withdrawal times and polyp detection rates

    Nielsen, A. B., Nielsen, Ole Haagen & Hendel, J., 2017, In: BMJ Open Gastroenterology. 4, 6 p., e000142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

    Bjerrum, J. T., Steenholdt, C., Ainsworth, M., Nielsen, Ole Haagen, Reed, M. A. C., Atkins, K., Günther, U. L., Hao, F. & Wang, Y., 2017, In: BMC Medicine. 15, 1, 13 p., 184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Modulation of Gut Microbiota in Pathological States

    Wang, Y., Wang, B., Wu, J., Jiang, X., Tang, H. & Nielsen, Ole Haagen, 2017, In: Engineering. 3, 1, p. 83-89 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Regulation of laminin γ2 expression by CDX2 in colonic epithelial cells is impaired during active inflammation

    Coskun, M., Soendergaard, C., Joergensen, S., Dahlgaard, K., Riis, Lene Buhl, Nielsen, Ole Haagen, Sandelin, Albin Gustav & Troelsen, J. T., 2017, In: Journal of Cellular Biochemistry. 118, 2, p. 298-307 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

    Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2016
  16. Published

    Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study

    Bojesen, R. D., Andersson, M., Riis, Lene Buhl, Nielsen, Ole Haagen & Jess, T., Sep 2016, In: Journal of Gastroenterology. 51, 9, p. 891-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes

    Søndergaard, C., Kvist, P. H., Seidelin, Jakob Benedict, Pelzer, H. & Nielsen, Ole Haagen, Aug 2016, In: Journal of Gastroenterology. 51, 8, p. 796-807 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mechanisms behind efficacy of tumor necrosis factor inhibitors in inflammatory bowel diseases

    Olesen, C. M., Coskun, M., Peyrin-Biroulet, L. & Nielsen, Ole Haagen, Mar 2016, In: Pharmacology & Therapeutics. 159, p. 110-119 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Circulating cytokines and cytokine receptors in infliximab treatment failure due to TNF-α independent Crohn disease

    Steenholdt, Casper, Coskun, M., Buhl, S., Bendtzen, K., Ainsworth, M. A., Brynskov, J. & Nielsen, Ole Haagen, 2016, In: Medicine (Baltimore). 95, 16, 8 p., e3417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Iron replacement therapy: do we need new guidelines?

    Nielsen, Ole Haagen, Coskun, M. & Weiss, G., 2016, In: Current Opinion in Gastroenterology. 32, 2, p. 128-135 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Pharmacology and optimization of thiopurines and methotrexate in inflammatory bowel disease

    Coskun, M., Steenholdt, Casper, de Boer, N. K. & Nielsen, Ole Haagen, 2016, In: Clinical Pharmacokinetics. 55, 3, p. 257-274 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Will novel oral formulations change the management of inflammatory bowel disease?

    Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Ainsworth, M. A. & Coskun, M., 2016, In: Expert Opinion on Investigational Drugs. 25, 6, p. 709-718 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. 2015
  24. Published

    Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease

    Salem, M., Nielsen, Ole Haagen, Nys, K., Yazdanyar, S. & Seidelin, Jakob Benedict, Nov 2015, In: Clinical and Translational Gastroenterology. 6, 9 p., e122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Preface

    Rogler, G., Herfarth, H., Hibi, T. & Nielsen, Ole Haagen, 9 Jul 2015, Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease. Karger, p. viii

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearchpeer-review

  26. Published

    Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD

    Casén, C., Vebø, H. C., Sekelja, M., Hegge, F. T., Karlsson, M. K., Ciemniejewska, E., Dzankovic, S., Frøyland, C., Nestestog, R., Engstrand, L., Munkholm, Pia, Nielsen, Ole Haagen, Rogler, G., Simrén, M., Öhman, L., Vatn, M. H. & Rudi, K., Jul 2015, In: Alimentary Pharmacology and Therapeutics. 42, 1, p. 71-83 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review

    Nielsen, Ole Haagen, Ainsworth, M., Coskun, M. & Weiss, G., Jun 2015, In: Medicine (Baltimore). 94, 23, p. 1-14 14 p., e963.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Alpha-1 antitrypsin and granulocyte colony-stimulating factor as serum biomarkers of disease severity in ulcerative colitis

    Soendergaard, C., Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Kvist, P. H. & Bjerrum, J. T., May 2015, In: Inflammatory Bowel Diseases. 21, 5, p. 1077-88 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    ATG16L1: A multifunctional susceptibility factor in Crohn disease

    Salem, M., Ammitzboell, M., Nys, K., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 3 Apr 2015, In: Autophagy. 11, 4, p. 585-94 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants

    Salem, M., Seidelin, Jakob Benedict, Eickhardt-Dalbøge, S. R., Alhede, M., Rogler, G. & Nielsen, Ole Haagen, Mar 2015, In: Clinical and Experimental Immunology. 179, 3, p. 426-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis

    Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Integrative Transcriptomic and Metabonomic Molecular Profiling of Colonic Mucosal Biopsies Indicates a Unique Molecular Phenotype for Ulcerative Colitis

    Rantalainen, M., Bjerrum, Jakob Tveiten , Olsen, Jørgen, Nielsen, Ole Haagen & Wang, Y., 2 Jan 2015, In: Journal of Proteome Research. 14, 1, p. 479-90 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation

    Seidelin, Jakob Benedict, Larsen, S., Linnemann, D., Vainer, B., Coskun, M., Troelsen, J. T. & Nielsen, Ole Haagen, Jan 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 308, 2, p. G92-G99 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Anti-TNF-α Therapy for Extraintestinal Manifestations of Inflammatory Bowel Disease

    Nielsen, Ole Haagen, Bendtzen, K. & Pedersen, J., 2015, In: Frontiers of Gastrointestinal Research. 34, p. 206-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals

    Bjerrum, Jakob Tveiten , Wang, Y., Hao, F., Coskun, M., Ludwig, C., Guenther, U. & Nielsen, Ole Haagen, 2015, In: Metabolomics. 11, 1, p. 122-133 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Objective Quantification of Immune Cell Infiltrates and Epidermal Proliferation in Psoriatic Skin: A Comparison of Digital Image Analysis and Manual Counting

    Soendergaard, C., Nielsen, Ole Haagen, Skak, K., Røpke, M. A., Seidelin, Jakob Benedict & Kvist, P. H., 2015, In: Applied Immunohistochemistry & Molecular Morphology. p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The role and advances of immunomodulator therapy for inflammatory bowel disease

    Nielsen, Ole Haagen, Coskun, M., Steenholdt, Casper & Rogler, G., 2015, In: Expert Review of Gastroenterology & Hepatology. 9, 2, p. 177-189 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. 2014
  39. Published

    Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia

    Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Riis, Lene Buhl, Pittet, V., Mueller, C., Rogler, G. & Olsen, Jørgen, Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation

    Pedersen, J., LaCasse, E. C., Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, Nov 2014, In: Trends in Molecular Medicine. 20, 11, p. 652-65 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Prognosis After First-Time Myocardial Infarction in Patients With Inflammatory Bowel Disease According to Disease Activity: Nationwide Cohort Study

    Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Erichsen, R., Lamberts, M., Khalid, U., Nielsen, Ole Haagen, Torp-Pedersen, Christian, Gislason, Gunnar Hilmar & Hansen, Peter Riis, Nov 2014, In: Circulation. Cardiovascular Quality and Outcomes (Print). 7, 6, p. 857-862 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Inflammatory Bowel Disease Is Associated With an Increased Risk of Hospitalization for Heart Failure: a Danish Nationwide Cohort A Danish Nationwide Cohort Study

    Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Erichsen, R., Lamberts, M., Khalid, U., Nielsen, Ole Haagen, Torp-Pedersen, C., Gislason, G. H. & Hansen, Peter Riis, Sep 2014, In: Circulation: Heart Failure. 7, 5, p. 717-722 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Proximal collagenous gastroenteritides: Clinical management. A systematic review

    Nielsen, Ole Haagen, Riis, Lene Buhl, Danese, S., Bojesen, R. D. & Soendergaard, C., Aug 2014, In: Annals of Medicine. 46, 5, p. 311-317 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease

    Bjerrum, Jakob Tveiten , Nyberg, C., Olsen, Jørgen & Nielsen, Ole Haagen, May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Increased risk of atrial fibrillation and stroke during active stages of inflammatory bowel disease: a nationwide study

    Kristensen, S. L., Lindhardsen, J., Ahlehoff, O., Erichsen, R., Lamberts, M., Khalid, U., Torp-Pedersen, C., Nielsen, Ole Haagen, Gislason, Gunnar Hilmar & Hansen, Peter Riis, Apr 2014, In: Europace. 16, 4, p. 477-484 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Inflammatory pathways of importance for management of inflammatory bowel disease

    Pedersen, J., Coskun, M., Soendergaard, C., Salem, M. & Nielsen, Ole Haagen, 7 Jan 2014, In: World Journal of Gastroenterology. 20, 1, p. 64-77 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Collagenous sprue: a coeliac disease look-alike with different treatment strategy

    Soendergaard, C., Riis, Lene Buhl & Nielsen, Ole Haagen, 2014, In: BMJ Case Reports. 2014

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    IBD medications during pregnancy and lactation

    Nielsen, Ole Haagen, Maxwell, C. & Hendel, J., 2014, In: Nature Reviews. Gastroenterology & Hepatology. 11, 2, p. 116-127 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2

    Boyd, M., Coskun, M., Lilje, B., Andersson, Robin, Hoof, I., Lange, Jette Bornholdt, Dahlgaard, K., Olsen, Jørgen, Vitezic, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Troelsen, J. & Sandelin, Albin Gustav, 2014, In: D N A Research. 21, 6, p. 569-583 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

    Bjerrum, Jakob Tveiten , Rantalainen, M., Wang, Y., Olsen, Jørgen & Nielsen, Ole Haagen, 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2

    Coskun, M., Olsen, A. K., Bzorek, M., Holck, S., Engel, U. H., Nielsen, Ole Haagen & Troelsen, J. T., 2014, In: Carcinogenesis. 35, 5, p. 1185-1192 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Letter: European Medicines Agency recommendations for allergic reactions to intravenous iron-containing medicines

    Gomollõn, F., Chowers, Y., Danese, S., Dignass, A., Nielsen, Ole Haagen, Lakatos, P. L., Lees, C. W., Lindgren, S., Lukas, M., Mantzaris, G. J., Michetti, P., Moum, B., Peyrin-Biroulet, L., Toruner, M., Van Der Woude, J., Weiss, G., Stoevelaar, H. & Reinisch, W., 2014, In: Alimentary Pharmacology and Therapeutics. 39, 7, p. 743-744

    Research output: Contribution to journalComment/debateResearch

  53. Published

    New strategies for treatment of inflammatory bowel disease

    Nielsen, Ole Haagen, 2014, In: Frontiers in Medicine. 1, p. 1-5 5 p., 3.

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    Which Biological Agents Are Most Appropriate for Ulcerative Colitis?

    Nielsen, Ole Haagen & Ainsworth, M. A., 2014, In: Annals of Internal Medicine. 160, 10, p. 733-734 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

ID: 4947702