Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology


  1. Published

    Magnetisk resonans-kolografi: Et nyt diagnostisk værktøj

    Achiam, Michael Patrick, Chabanova, E., Løgager, V. B., Thomsen, Henrik S. & Nielsen, Ole Haagen, 7 Nov 2005, In: Ugeskrift for Laeger. 167, 45, p. 4279-4284 6 p.

    Research output: Contribution to journalReviewpeer-review

  2. Published

    Sulfasalazine and its anti-inflammatory metabolite, 5-aminosalicylic acid: effect on arachidonic acid metabolism in human neutrophils, and free radical scavenging

    Ahnfelt-Rønne, I., Nielsen, Ole Haagen, Bukhave, K. & Elmgreen, J., 1987, In: Advances in prostaglandin, thromboxane, and leukotriene research. 17B, p. 918-22 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    The antiinflammatory moiety of sulfasalazine, 5-aminosalicylic acid, is a radical scavenger

    Ahnfelt-Rønne, I. & Nielsen, Ole Haagen, Jun 1987, In: Agents and Actions. 21, 1-2, p. 191-4 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid

    Ahnfelt-Rønne, I., Nielsen, Ole Haagen, Christensen, A., Langholz, Ebbe, Binder, V. & Riis, P., May 1990, In: Gastroenterology. 98, 5 Pt 1, p. 1162-9 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Farmakogenetik--en ny behandlingsmulighed

    Ainsworth, M. A. & Nielsen, Ole Haagen, 16 May 2005, In: Ugeskrift for Laeger. 167, 20, p. 2141

    Research output: Contribution to journalJournal article

  6. Published

    Transjugulær intrahepatisk portosystemisk stent-shunts eller paracentese ved behandling af cirrosepatienter med refraktær ascites

    Ainsworth, M. A. & Nielsen, Ole Haagen, 29 Aug 2005, In: Ugeskrift for Laeger. 167, 35, p. 3273-3276 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Tumornekrosefaktor alpha-antistof-behandling til vedligeholdelse af remission ved Crohns sygdom

    Al-Subeihe, I. & Nielsen, Ole Haagen, 2008, In: Ugeskrift for læger. 170, 50, p. 4130-4134 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

    Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.

    Research output: Contribution to journalReviewpeer-review

  9. Published

    A proposal for a study on treatment selection and lifestyle recommendations in chronic inflammatory diseases: A danish multidisciplinary collaboration on prognostic factors and personalised medicine

    Andersen, V., Holmskov, U., Bek Sørensen, S., Jawhara, M., Andersen, K. W., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F., Nielsen, O. H. & 18 others, Christensen, R., Bo Bojesen, A., Sorensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Heitmann, Berit, Boye, M., Nielsen, C. L., Werner, L., Kjeldsen, J. & Ellingsen, T., May 2017, In: Nutrients. 9, 5, 16 p., 499.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Kronisk inflammatorisk tarmsygdom i relation til graviditet

    Andreasson, B., Nielsen, Ole Haagen, Bondesen, S., Jacobsen, O. & Jarnum, S., 4 Jun 1984, In: Ugeskrift for Laeger. 146, 23, p. 1708-10 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis

    Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

    Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue

    Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease

    Bjerrum, Jakob Tveiten , Nyberg, C., Olsen, Jørgen & Nielsen, Ole Haagen, May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Azathioprin og 6-mercaptopurin som vedligeholdelsesbehandling ved colitis ulcerosa: Gennemgang af Cochrane-review

    Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 12 Oct 2007, In: Ugeskrift for Laeger. 169, 50, p. 4341-4344 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology

    Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Hao, F., Tang, H., Nicholson, J. K., Wang, Y., Olsen, Jørgen, Bjerrum, J. T., Nielsen, Ole Haagen, Shen, H., Tang, H. R., Nicholson, J. B., Wang, L. & Olsen, J., 2010, In: Journal of Proteome Research. 9, 2, p. 954-962 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia

    Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Riis, Lene Buhl, Pittet, V., Mueller, C., Rogler, G. & Olsen, Jørgen, Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    IBD metabonomics predicts phenotype, disease course, and treatment response

    Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.

    Research output: Contribution to journalReviewpeer-review

  19. Published

    Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

    Bjerrum, J. T., Steenholdt, C., Ainsworth, M., Nielsen, Ole Haagen, Reed, M. A. C., Atkins, K., Günther, U. L., Hao, F. & Wang, Y., 2017, In: BMC Medicine. 15, 1, 13 p., 184.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    5-aminosalicylsyre til induktion af remission eller respons ved Crohns sygdom--en gennemgang af et Cochranereview

    Bjerrum, J. T., Munck, L. K. & Nielsen, Ole Haagen, 2011, In: Ugeskrift for Laeger. 173, 35, p. 2110-3 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

    Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Wang, Y. L. & Olsen, Jørgen, 2008, In: Nature Clinical Practice Gastroenterology & Hepatology. 5, 6, p. 332-43 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

    Bjerrum, Jakob Tveiten , Rantalainen, M., Wang, Y., Olsen, Jørgen & Nielsen, Ole Haagen, 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    TNF-α-antistofbehandling og remissionsinduktion ved colitis ulcerosa: Gennemgang af et Cochrane-review

    Bjerrum, Jakob Tveiten , Munck, Lars Kristian, Krogh-Madsen, M. & Nielsen, Ole Haagen, 26 Feb 2007, In: Ugeskrift for Laeger. 169, 9, p. 792-795 4 p.

    Research output: Contribution to journalReviewpeer-review

  24. Published

    Metabonomics in gastroenterology and hepatology

    Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.

    Research output: Contribution to journalEditorialpeer-review

  25. Published

    Genome-wide Gene Expression Analysis of Mucosal Colonic Biopsies and Isolated Colonocytes Suggests a Continuous Inflammatory State in the Lamina Propria of Patients with Quiescent Ulcerative Colitis

    Bjerrum, Jakob Tveiten , Hansen, M., Olsen, Jørgen, Nielsen, Ole Haagen, Bjerrum, J. T., Hansen, M., Olsen, J. & Nielsen, Ole Haagen, 2010, In: Inflammatory Bowel Diseases. 16, 6, p. 999-1007 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets

    Bjerrum, Jakob Tveiten , Wang, Y., Zhang, J., Riis, Lene Buhl, Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Perioperativ blodtransfusion og recidiv af karcinom i colon og rectum: Gennemgang af et Cochrane-review

    Bjerrum, Jakob Tveiten , Jensen, L. S. & Nielsen, Ole Haagen, 21 Aug 2006, In: Ugeskrift for Laeger. 168, 34, 1 p.

    Research output: Contribution to journalReviewpeer-review

  28. Published

    Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals

    Bjerrum, Jakob Tveiten , Wang, Y., Hao, F., Coskun, M., Ludwig, C., Guenther, U. & Nielsen, Ole Haagen, 2015, In: Metabolomics. 11, 1, p. 122-133 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study

    Bojesen, R. D., Riis, Lene Buhl, Høgdall, Estrid Vilma Solyom, Nielsen, Ole Haagen & Jess, T., Dec 2017, In: Clinical Gastroenterology and Hepatology. 15, 12, p. 1900-1907.e2

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study

    Bojesen, R. D., Andersson, M., Riis, Lene Buhl, Nielsen, Ole Haagen & Jess, T., Sep 2016, In: Journal of Gastroenterology. 51, 9, p. 891-9 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. 5-Aminosalicylic acid in the treatment of inflammatory bowel disease

    Bondesen, S., Rasmussen, S. N., Rask-Madsen, J., Nielsen, Ole Haagen, Lauritsen, K., Binder, V., Hansen, S. H. & Hvidberg, E. F., 1987, In: Acta Medica Scandinavica. 221, 3, p. 227-42 16 p.

    Research output: Contribution to journalReviewpeer-review

  32. Steady-state kinetics of 5-aminosalicylic acid and sulfapyridine during sulfasalazine prophylaxis in ulcerative colitis

    Bondesen, S., Nielsen, Ole Haagen, Schou, J. B., Jensen, P. H., Lassen, L. B., Binder, V., Krasilnikoff, P. A., Danø, P., Hansen, S. H. & Rasmussen, S. N., 1986, In: Scandinavian Journal of Gastroenterology. 21, 6, p. 693-700 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. 5-Aminosalicylic acid enemas in patients with active ulcerative colitis. Influence of acidity on the kinetic pattern

    Bondesen, S., Nielsen, Ole Haagen, Jacobsen, O., Rasmussen, S. N., Hansen, S. H., Halskov, S., Binder, V. & Hvidberg, E. F., 1984, In: Scandinavian Journal of Gastroenterology. 19, 5, p. 677-82 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Microarray-dataanalyse

    Borup, R. H. A., vlz241, vlz241, Nielsen, Ole Haagen & Nielsen, Finn Cilius, 29 May 2006, In: Ugeskrift for Laeger. 168, 22, p. 2159-2162 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Interleukin-4 and 13 induce the expression and release of monocyte chemoattractant protein 1, interleukin-6 and stem cell factor from human detrusor smooth muscle cells: synergy with interleukin-1beta and tumor necrosis factor-alpha

    Bouchelouche, K., Andresen, Lars, Alvarez, S., Nordling, J., Nielsen, Ole Haagen & Bouchelouche, P., 2006, In: Journal of Urology. 175, 2, p. 760-5 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Recombinant human tumour necrosis factor increases cytosolic free calcium in murine fibroblasts and stimulates inositol phosphate formation in L-M and arachidonic acid release in 3T3 cells

    Bouchelouche, P. N., Bendtzen, K., Bak, Søren & Nielsen, Ole Haagen, 1990, In: Cellular Signalling. 2, 5, p. 479-87 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Leukotriene B4 receptor levels and intracellular calcium signalling in polymorphonuclear leukocytes from patients with Crohn's disease

    Bouchelouche, P. N., Berild, D., Nielsen, Ole Haagen, Elmgreen, J. & Poulsen, H. S., Apr 1995, In: European journal of gastroenterology & hepatology. 7, 4, p. 349-56 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2

    Boyd, M., Coskun, M., Lilje, B., Andersson, Robin, Hoof, I., Lange, Jette Bornholdt, Dahlgaard, K., Olsen, Jørgen, Vitezic, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Troelsen, J. & Sandelin, Albin Gustav, 2014, In: D N A Research. 21, 6, p. 569-583 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

    Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease

    Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Autoantibodies to molecular targets in neutrophils in patients with ulcerative colitis

    Brimnes, J., Nielsen, Ole Haagen, Wiik, A. & Heegaard, N. H. H., 1 Jan 1999, In: Digestive Diseases and Sciences. 44, 2, p. 415-423 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Mitogen activated protein kinases: a role in inflammatory bowel disease?

    Broom, O. J., Widjaya, B., Troelsen, J., Olsen, Jørgen & Nielsen, Ole Haagen, 2009, In: Clinical and Experimental Immunology. 158, 3, p. 272-80 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Cysteinylleukotrieners betydning for kronisk inflammation og neoplasi i tarmen

    Broom, O. J. & Nielsen, Ole Haagen, 2009, In: Ugeskrift for læger. 171, 4, p. 243-6 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Cytokines in inflammatory bowel disease

    Brynskov, J., Nielsen, Ole Haagen, Ahnfelt-Rønne, I. & Bendtzen, K., Nov 1992, In: Scandinavian Journal of Gastroenterology. 27, 11, p. 897-906 10 p.

    Research output: Contribution to journalReviewpeer-review

  45. Published

    Cytokines (immunoinflammatory hormones) and their natural regulation in inflammatory bowel disease (Crohn's disease and ulcerative colitis): a review

    Brynskov, J., Nielsen, Ole Haagen, Ahnfelt-Rønne, I. & Bendtzen, K., 1 Sep 1994, In: Digestive Diseases. 12, 5, p. 290-304 15 p.

    Research output: Contribution to journalReviewpeer-review

  46. Published

    Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD

    Casén, C., Vebø, H. C., Sekelja, M., Hegge, F. T., Karlsson, M. K., Ciemniejewska, E., Dzankovic, S., Frøyland, C., Nestestog, R., Engstrand, L., Munkholm, Pia, Nielsen, Ole Haagen, Rogler, G., Simrén, M., Öhman, L., Vatn, M. H. & Rudi, K., Jul 2015, In: Alimentary Pharmacology and Therapeutics. 42, 1, p. 71-83 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Telomere dysfunction activates YAP1 to drive tissue inflammation

    Chakravarti, D., Hu, B., Mao, X., Rashid, A., Li, J., Li, J., Liao, W. T., Whitley, E. M., Dey, P., Hou, P., LaBella, K. A., Chang, A., Wang, G., Spring, D. J., Deng, P., Zhao, D., Liang, X., Lan, Z., Lin, Y., Sarkar, S. & 16 others, Terranova, C., Deribe, Y. L., Blutt, S. E., Okhuysen, P., Zhang, J., Vilar, E., Nielsen, Ole Haagen, Dupont, A., Younes, M., Patel, K. R., Shroyer, N. F., Rai, K., Estes, M. K., Wang, Y. A., Bertuch, A. A. & DePinho, R. A., 2020, In: Nature Communications. 11, 13 p., 4766.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Telomere dysfunction instigates inflammation in inflammatory bowel disease

    Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W. H., Chang, K., Reyes, L., Rashid, A., Wu, C. J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E. & 9 others, Zhang, J., Younes, M., DuPont, A., Thirumurthi, S., Vilar, E., Estes, M. K., Colla, S., Shroyer, N. F. & DePinho, R. A., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

    Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

    Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, Bojesen, A. B., Sørensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexoe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., 2018, In: BMJ Open. 8, 2, 15 p., :e018166.

    Research output: Contribution to journalJournal articlepeer-review

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ID: 4947702