Ole Haagen Nielsen
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Denmark
Member of:
Internal Medicine: Gastroenterology and Hepatology
- Published
Magnetisk resonans-kolografi: Et nyt diagnostisk værktøj
Achiam, Michael Patrick, Chabanova, E., Løgager, V. B., Thomsen, Henrik S. & Nielsen, Ole Haagen, 7 Nov 2005, In: Ugeskrift for Laeger. 167, 45, p. 4279-4284 6 p.Research output: Contribution to journal › Review › peer-review
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Sulfasalazine and its anti-inflammatory metabolite, 5-aminosalicylic acid: effect on arachidonic acid metabolism in human neutrophils, and free radical scavenging
Ahnfelt-Rønne, I., Nielsen, Ole Haagen, Bukhave, K. & Elmgreen, J., 1987, In: Advances in prostaglandin, thromboxane, and leukotriene research. 17B, p. 918-22 5 p.Research output: Contribution to journal › Journal article › peer-review
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The antiinflammatory moiety of sulfasalazine, 5-aminosalicylic acid, is a radical scavenger
Ahnfelt-Rønne, I. & Nielsen, Ole Haagen, Jun 1987, In: Agents and Actions. 21, 1-2, p. 191-4 4 p.Research output: Contribution to journal › Journal article › peer-review
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Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid
Ahnfelt-Rønne, I., Nielsen, Ole Haagen, Christensen, A., Langholz, Ebbe, Binder, V. & Riis, P., May 1990, In: Gastroenterology. 98, 5 Pt 1, p. 1162-9 8 p.Research output: Contribution to journal › Journal article › peer-review
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Farmakogenetik--en ny behandlingsmulighed
Ainsworth, M. A. & Nielsen, Ole Haagen, 16 May 2005, In: Ugeskrift for Laeger. 167, 20, p. 2141Research output: Contribution to journal › Journal article
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Transjugulær intrahepatisk portosystemisk stent-shunts eller paracentese ved behandling af cirrosepatienter med refraktær ascites
Ainsworth, M. A. & Nielsen, Ole Haagen, 29 Aug 2005, In: Ugeskrift for Laeger. 167, 35, p. 3273-3276 4 p.Research output: Contribution to journal › Journal article › peer-review
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Tumornekrosefaktor alpha-antistof-behandling til vedligeholdelse af remission ved Crohns sygdom
Al-Subeihe, I. & Nielsen, Ole Haagen, 2008, In: Ugeskrift for læger. 170, 50, p. 4130-4134 4 p.Research output: Contribution to journal › Journal article › peer-review
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Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease
Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.Research output: Contribution to journal › Review › peer-review
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A proposal for a study on treatment selection and lifestyle recommendations in chronic inflammatory diseases: A danish multidisciplinary collaboration on prognostic factors and personalised medicine
Andersen, V., Holmskov, U., Bek Sørensen, S., Jawhara, M., Andersen, K. W., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F., Nielsen, O. H. & 18 others, , May 2017, In: Nutrients. 9, 5, 16 p., 499.Research output: Contribution to journal › Journal article › peer-review
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Kronisk inflammatorisk tarmsygdom i relation til graviditet
Andreasson, B., Nielsen, Ole Haagen, Bondesen, S., Jacobsen, O. & Jarnum, S., 4 Jun 1984, In: Ugeskrift for Laeger. 146, 23, p. 1708-10 3 p.Research output: Contribution to journal › Journal article › peer-review
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Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis
Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.Research output: Contribution to journal › Review › peer-review
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Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy
Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.Research output: Contribution to journal › Journal article › peer-review
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A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue
Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.Research output: Contribution to journal › Journal article › peer-review
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Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease
Bjerrum, Jakob Tveiten , Nyberg, C., Olsen, Jørgen & Nielsen, Ole Haagen, May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.Research output: Contribution to journal › Journal article › peer-review
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Azathioprin og 6-mercaptopurin som vedligeholdelsesbehandling ved colitis ulcerosa: Gennemgang af Cochrane-review
Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 12 Oct 2007, In: Ugeskrift for Laeger. 169, 50, p. 4341-4344 4 p.Research output: Contribution to journal › Journal article › peer-review
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Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology
Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Hao, F., Tang, H., Nicholson, J. K., Wang, Y., Olsen, Jørgen, Bjerrum, J. T., Nielsen, Ole Haagen, Shen, H., Tang, H. R., Nicholson, J. B., Wang, L. & Olsen, J., 2010, In: Journal of Proteome Research. 9, 2, p. 954-962 9 p.Research output: Contribution to journal › Journal article › peer-review
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Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia
Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Riis, Lene Buhl, Pittet, V., Mueller, C., Rogler, G. & Olsen, Jørgen, Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.Research output: Contribution to journal › Journal article › peer-review
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IBD metabonomics predicts phenotype, disease course, and treatment response
Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.Research output: Contribution to journal › Review › peer-review
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Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease
Bjerrum, J. T., Steenholdt, C., Ainsworth, M., Nielsen, Ole Haagen, Reed, M. A. C., Atkins, K., Günther, U. L., Hao, F. & Wang, Y., 2017, In: BMC Medicine. 15, 1, 13 p., 184.Research output: Contribution to journal › Journal article › peer-review
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5-aminosalicylsyre til induktion af remission eller respons ved Crohns sygdom--en gennemgang af et Cochranereview
Bjerrum, J. T., Munck, L. K. & Nielsen, Ole Haagen, 2011, In: Ugeskrift for Laeger. 173, 35, p. 2110-3 4 p.Research output: Contribution to journal › Journal article › peer-review
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Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.
Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Wang, Y. L. & Olsen, Jørgen, 2008, In: Nature Clinical Practice Gastroenterology & Hepatology. 5, 6, p. 332-43 11 p.Research output: Contribution to journal › Journal article › peer-review
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Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis
Bjerrum, Jakob Tveiten , Rantalainen, M., Wang, Y., Olsen, Jørgen & Nielsen, Ole Haagen, 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.Research output: Contribution to journal › Journal article › peer-review
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TNF-α-antistofbehandling og remissionsinduktion ved colitis ulcerosa: Gennemgang af et Cochrane-review
Bjerrum, Jakob Tveiten , Munck, Lars Kristian, Krogh-Madsen, M. & Nielsen, Ole Haagen, 26 Feb 2007, In: Ugeskrift for Laeger. 169, 9, p. 792-795 4 p.Research output: Contribution to journal › Review › peer-review
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Metabonomics in gastroenterology and hepatology
Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.Research output: Contribution to journal › Editorial › peer-review
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Genome-wide Gene Expression Analysis of Mucosal Colonic Biopsies and Isolated Colonocytes Suggests a Continuous Inflammatory State in the Lamina Propria of Patients with Quiescent Ulcerative Colitis
Bjerrum, Jakob Tveiten , Hansen, M., Olsen, Jørgen, Nielsen, Ole Haagen, Bjerrum, J. T., Hansen, M., Olsen, J. & Nielsen, Ole Haagen, 2010, In: Inflammatory Bowel Diseases. 16, 6, p. 999-1007 9 p.Research output: Contribution to journal › Journal article › peer-review
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Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets
Bjerrum, Jakob Tveiten , Wang, Y., Zhang, J., Riis, Lene Buhl, Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.Research output: Contribution to journal › Journal article › peer-review
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Perioperativ blodtransfusion og recidiv af karcinom i colon og rectum: Gennemgang af et Cochrane-review
Bjerrum, Jakob Tveiten , Jensen, L. S. & Nielsen, Ole Haagen, 21 Aug 2006, In: Ugeskrift for Laeger. 168, 34, 1 p.Research output: Contribution to journal › Review › peer-review
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Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals
Bjerrum, Jakob Tveiten , Wang, Y., Hao, F., Coskun, M., Ludwig, C., Guenther, U. & Nielsen, Ole Haagen, 2015, In: Metabolomics. 11, 1, p. 122-133 12 p.Research output: Contribution to journal › Journal article › peer-review
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Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study
Bojesen, R. D., Riis, Lene Buhl, Høgdall, Estrid Vilma Solyom, Nielsen, Ole Haagen & Jess, T., Dec 2017, In: Clinical Gastroenterology and Hepatology. 15, 12, p. 1900-1907.e2Research output: Contribution to journal › Journal article › peer-review
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Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study
Bojesen, R. D., Andersson, M., Riis, Lene Buhl, Nielsen, Ole Haagen & Jess, T., Sep 2016, In: Journal of Gastroenterology. 51, 9, p. 891-9 9 p.Research output: Contribution to journal › Journal article › peer-review
5-Aminosalicylic acid in the treatment of inflammatory bowel disease
Bondesen, S., Rasmussen, S. N., Rask-Madsen, J., Nielsen, Ole Haagen, Lauritsen, K., Binder, V., Hansen, S. H. & Hvidberg, E. F., 1987, In: Acta Medica Scandinavica. 221, 3, p. 227-42 16 p.Research output: Contribution to journal › Review › peer-review
Steady-state kinetics of 5-aminosalicylic acid and sulfapyridine during sulfasalazine prophylaxis in ulcerative colitis
Bondesen, S., Nielsen, Ole Haagen, Schou, J. B., Jensen, P. H., Lassen, L. B., Binder, V., Krasilnikoff, P. A., Danø, P., Hansen, S. H. & Rasmussen, S. N., 1986, In: Scandinavian Journal of Gastroenterology. 21, 6, p. 693-700 8 p.Research output: Contribution to journal › Journal article › peer-review
5-Aminosalicylic acid enemas in patients with active ulcerative colitis. Influence of acidity on the kinetic pattern
Bondesen, S., Nielsen, Ole Haagen, Jacobsen, O., Rasmussen, S. N., Hansen, S. H., Halskov, S., Binder, V. & Hvidberg, E. F., 1984, In: Scandinavian Journal of Gastroenterology. 19, 5, p. 677-82 6 p.Research output: Contribution to journal › Journal article › peer-review
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Microarray-dataanalyse
Borup, R. H. A., vlz241, vlz241, Nielsen, Ole Haagen & Nielsen, Finn Cilius, 29 May 2006, In: Ugeskrift for Laeger. 168, 22, p. 2159-2162 4 p.Research output: Contribution to journal › Journal article › peer-review
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Interleukin-4 and 13 induce the expression and release of monocyte chemoattractant protein 1, interleukin-6 and stem cell factor from human detrusor smooth muscle cells: synergy with interleukin-1beta and tumor necrosis factor-alpha
Bouchelouche, K., Andresen, Lars, Alvarez, S., Nordling, J., Nielsen, Ole Haagen & Bouchelouche, P., 2006, In: Journal of Urology. 175, 2, p. 760-5 6 p.Research output: Contribution to journal › Journal article › peer-review
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Recombinant human tumour necrosis factor increases cytosolic free calcium in murine fibroblasts and stimulates inositol phosphate formation in L-M and arachidonic acid release in 3T3 cells
Bouchelouche, P. N., Bendtzen, K., Bak, Søren & Nielsen, Ole Haagen, 1990, In: Cellular Signalling. 2, 5, p. 479-87 9 p.Research output: Contribution to journal › Journal article › peer-review
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Leukotriene B4 receptor levels and intracellular calcium signalling in polymorphonuclear leukocytes from patients with Crohn's disease
Bouchelouche, P. N., Berild, D., Nielsen, Ole Haagen, Elmgreen, J. & Poulsen, H. S., Apr 1995, In: European journal of gastroenterology & hepatology. 7, 4, p. 349-56 8 p.Research output: Contribution to journal › Journal article › peer-review
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Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Boyd, M., Coskun, M., Lilje, B., Andersson, Robin, Hoof, I., Lange, Jette Bornholdt, Dahlgaard, K., Olsen, Jørgen, Vitezic, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Troelsen, J. & Sandelin, Albin Gustav, 2014, In: D N A Research. 21, 6, p. 569-583 15 p.Research output: Contribution to journal › Journal article › peer-review
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Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › peer-review
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Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease
Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457Research output: Contribution to journal › Journal article › peer-review
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Autoantibodies to molecular targets in neutrophils in patients with ulcerative colitis
Brimnes, J., Nielsen, Ole Haagen, Wiik, A. & Heegaard, N. H. H., 1 Jan 1999, In: Digestive Diseases and Sciences. 44, 2, p. 415-423 9 p.Research output: Contribution to journal › Journal article › peer-review
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Mitogen activated protein kinases: a role in inflammatory bowel disease?
Broom, O. J., Widjaya, B., Troelsen, J., Olsen, Jørgen & Nielsen, Ole Haagen, 2009, In: Clinical and Experimental Immunology. 158, 3, p. 272-80 8 p.Research output: Contribution to journal › Journal article › peer-review
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Cysteinylleukotrieners betydning for kronisk inflammation og neoplasi i tarmen
Broom, O. J. & Nielsen, Ole Haagen, 2009, In: Ugeskrift for læger. 171, 4, p. 243-6 3 p.Research output: Contribution to journal › Journal article › peer-review
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Cytokines in inflammatory bowel disease
Brynskov, J., Nielsen, Ole Haagen, Ahnfelt-Rønne, I. & Bendtzen, K., Nov 1992, In: Scandinavian Journal of Gastroenterology. 27, 11, p. 897-906 10 p.Research output: Contribution to journal › Review › peer-review
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Cytokines (immunoinflammatory hormones) and their natural regulation in inflammatory bowel disease (Crohn's disease and ulcerative colitis): a review
Brynskov, J., Nielsen, Ole Haagen, Ahnfelt-Rønne, I. & Bendtzen, K., 1 Sep 1994, In: Digestive Diseases. 12, 5, p. 290-304 15 p.Research output: Contribution to journal › Review › peer-review
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Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD
Casén, C., Vebø, H. C., Sekelja, M., Hegge, F. T., Karlsson, M. K., Ciemniejewska, E., Dzankovic, S., Frøyland, C., Nestestog, R., Engstrand, L., Munkholm, Pia, Nielsen, Ole Haagen, Rogler, G., Simrén, M., Öhman, L., Vatn, M. H. & Rudi, K., Jul 2015, In: Alimentary Pharmacology and Therapeutics. 42, 1, p. 71-83 13 p.Research output: Contribution to journal › Journal article › peer-review
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Telomere dysfunction activates YAP1 to drive tissue inflammation
Chakravarti, D., Hu, B., Mao, X., Rashid, A., Li, J., Li, J., Liao, W. T., Whitley, E. M., Dey, P., Hou, P., LaBella, K. A., Chang, A., Wang, G., Spring, D. J., Deng, P., Zhao, D., Liang, X., Lan, Z., Lin, Y., Sarkar, S. & 16 others, , 2020, In: Nature Communications. 11, 13 p., 4766.Research output: Contribution to journal › Journal article › peer-review
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Telomere dysfunction instigates inflammation in inflammatory bowel disease
Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W. H., Chang, K., Reyes, L., Rashid, A., Wu, C. J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.Research output: Contribution to journal › Journal article › peer-review
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Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels
Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.Research output: Contribution to journal › Journal article › peer-review
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Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine
Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, , 2018, In: BMJ Open. 8, 2, 15 p., :e018166.Research output: Contribution to journal › Journal article › peer-review
ID: 4947702
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Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Research output: Contribution to journal › Journal article › peer-review
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Modulation of Gut Microbiota in Pathological States
Research output: Contribution to journal › Review › peer-review
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YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Research output: Contribution to journal › Journal article › peer-review
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