Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology

ORCID: 0000-0003-4612-8635

Publication year:
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1 - 50 out of 352Page size: 50
  1. 2024
  2. Published

    Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation

    Nielsen, Ole Haagen, Gubatan, J. M., Kolho, K., Streett, S. E. & Maxwell, C., 30 Mar 2024, In: The Lancet. 403, 10433, p. 1291-1303

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation

    Hausmann, Annika, Steenholdt, Casper, Nielsen, Ole Haagen & Jensen, Kim Bak, 20 Mar 2024, In: Trends in Molecular Medicine. 30, 3, p. 239-251

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care

    Nielsen, Ole Haagen & Pardi, D. S., 2024, In: Drugs and Aging. 41, p. 113-123 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Gut Microbiome and Disorders of the Gastrointestinal Tract

    Hammerhøj, A., Gubatan, J. M. & Nielsen, Ole Haagen, 2024, In: Microorganisms. 12, 3, 2 p., 576.

    Research output: Contribution to journal › Editorial › Research › peer-review

  6. Published

    IAPs and RIPK1 mediate LPS-induced cytokine production in healthy subjects and Crohn's disease

    Seidelin, Jakob Benedict, Jensen, Simone, Hansen, M., Bronze, M. R. D. C., Cuchet-Lourenҫo, D., Nejentsev, S., LaCasse, E. C. & Nielsen, Ole Haagen, 2024, In: Clinical and Experimental Immunology. 215, 3, p. 291–301 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Mirikizumab (Omvoh™) for ulcerative colitis

    Hammerhøj, A., Boye, T. L., Langholz, Ebbe & Nielsen, Ole Haagen, 2024, In: Trends in Pharmacological Sciences. 45, 3, p. 281-282 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2023
  9. Published

    Kinase Signaling in Colitis-Associated Colon Cancer and Inflammatory Bowel Disease

    Temby, M., Boye, T. L., Hoang, J., Nielsen, Ole Haagen & Gubatan, J., Nov 2023, In: Biomolecules. 13, 11, 14 p., 1620.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis

    Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Deucravacitinib (Sotyktu™) for plaque psoriasis

    Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253

    Research output: Contribution to journal › Letter › Research › peer-review

  12. Published

    Effectiveness of Non-Budesonide Therapies in Management of Microscopic Colitis: A Systematic Review and Meta-analysis

    Rehde, A., Hendel, S. K., Juhl, C. B., Gubatan, J. & Nielsen, Ole Haagen, 2023, In: Drugs. 83, 11, p. 1027-1038 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

    Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-analysis

    Gubatan, J., Barber, G. E., Nielsen, Ole Haagen, Juhl, C. B., Maxwell, C., Eisenberg, M. L. & Streett, S. E., 2023, In: Clinical Gastroenterology and Hepatology. 21, 9, p. 2222-2238 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Selective JAK1 inhibitors for the treatment of inflammatory bowel disease

    Nielsen, Ole Haagen, Boye, T. L., Gubatan, J., Chakravarti, D., Jaquith, J. B. & LaCasse, E. C., 2023, In: Pharmacology and Therapeutics. 245, 108402.

    Research output: Contribution to journal › Review › Research › peer-review

  16. 2022
  17. Published

    Microscopic colitis: Etiopathology, diagnosis, and rational management

    Nielsen, Ole Haagen, Fernandez-Banares, F., Sato, T. & Pardi, D. S., 1 Aug 2022, In: eLife. 11, 21 p., e79397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Biologics for Inflammatory Bowel Disease and their Safety in Pregnancy: A Systematic Review and Meta-analysis

    Nielsen, Ole Haagen, Gubatan, J. M., Juhl, C. B., Streett, S. E. & Maxwell, C., 2022, In: Clinical Gastroenterology and Hepatology. 20, 1, p. 74-87.e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis

    Holmstroem, R. B., Nielsen, Ole Haagen, Jacobsen, Søren, Riis, Lene Buhl, Theile, S., Bjerrum, Jakob Tveiten , Vilmann, Peter, Johansen, Julia Sidenius, Boisen, M. K., Eefsen, R. H. L., Svane, Inge Marie, Nielsen, Dorte Lisbet & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer

    Gubatan, J., Boye, T. L., Temby, M., Sojwal, R. S., Holman, D. R., Sinha, S. R., Rogalla, S. R. & Nielsen, Ole Haagen, 2022, In: Microorganisms. 10, 7, 1371.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Impact of fibre and red/processed meat intake on treatment outcomes among patients with chronic inflammatory diseases initiating biological therapy: A prospective cohort study

    Overgaard, S. H., Sørensen, S. B., Munk, H. L., Nexøe, A. B., Glerup, H., Henriksen, R. H., Guldmann, T., Pedersen, N., Saboori, S., Hvid, L., Dahlerup, J. F., Hvas, C. L., Jawhara, M., Andersen, K. W., Pedersen, A. K., Nielsen, O. H., Bergenheim, F., Brodersen, J. B., Heitmann, B. L., Halldorsson, T. I. & 6 others, Holmskov, U., Bygum, A., Christensen, R., Kjeldsen, J., Ellingsen, T. & Andersen, V., 2022, In: Frontiers in Nutrition. 9, 13 p., 985732.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets

    Bjerrum, Jakob Tveiten , Wang, Y., Zhang, J., Riis, Lene Buhl, Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease

    Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select

    Niu, Yiyuan, Ferreira Azevedo, Catarina A, Li, Xin, Kamali, E., Nielsen, Ole Haagen, Sørensen, Claus Storgaard & Frödin, Morten, 2022, In: Nature Genetics. 54, 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Reply

    Nielsen, Ole Haagen, Gubatan, J. & Juhl, C. B., 2022, In: Clinical Gastroenterology and Hepatology. 20, 4, p. 963-964

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  26. Published

    Selective tyrosine kinase 2 inhibitors in inflammatory bowel disease

    Nielsen, Ole Haagen, Boye, T. L., Chakravarti, D. & Gubatan, J., 2022, In: Trends in Pharmacological Sciences. 43, 5, p. 424-436

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Tuft Cells and Their Role in Intestinal Diseases

    Hendel, S. K., Kellermann, L., Hausmann, Annika, Bindslev, Niels, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Frontiers in Immunology. 13, 13 p., 822867.

    Research output: Contribution to journal › Review › Research › peer-review

  28. 2021
  29. Published

    Identification, isolation and analysis of human gut-associated lymphoid tissues

    Jørgensen, P. B., Fenton, T. M., Mörbe, U. M., Riis, Lene Buhl, Jakobsen, H. L., Nielsen, Ole Haagen & Agace, W. W., 22 Feb 2021, In: Nature Protocols. 16, p. 2051–2067

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis

    Gubatan, J. M., Nielsen, Ole Haagen, Levitte, S., Juhl, C. B., Maxwell, C., Streett, S. E. & Habtezion, A., 2021, In: Am J Gastroenterol. 116, 2, p. 243-253

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    IBD metabonomics predicts phenotype, disease course, and treatment response

    Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Telomere dysfunction instigates inflammation in inflammatory bowel disease

    Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W. H., Chang, K., Reyes, L., Rashid, A., Wu, C. J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E. & 9 others, Zhang, J., Younes, M., DuPont, A., Thirumurthi, S., Vilar, E., Estes, M. K., Colla, S., Shroyer, N. F. & DePinho, R. A., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2020
  34. Published

    Efficacy and safety of methotrexate in the management of inflammatory bowel disease: A systematic review and meta-analysis of randomized, controlled trials

    Nielsen, Ole Haagen, Steenholdt, C., Juhl, C. B. & Rogler, G., Mar 2020, In: EClinicalMedicine. 20, 10 p., 100271.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue

    Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity

    Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, Lene Buhl, Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., Brunak, Søren, Habtezion, A., Nielsen, Ole Haagen, Johansson-Lindbom, B. & Agace, W. W., 2020, In: Immunity. 52, 3, p. 557-570, e1-e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mucosal vitamin D signaling in inflammatory bowel disease

    Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

    Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Telomere dysfunction activates YAP1 to drive tissue inflammation

    Chakravarti, D., Hu, B., Mao, X., Rashid, A., Li, J., Li, J., Liao, W. T., Whitley, E. M., Dey, P., Hou, P., LaBella, K. A., Chang, A., Wang, G., Spring, D. J., Deng, P., Zhao, D., Liang, X., Lan, Z., Lin, Y., Sarkar, S. & 16 others, Terranova, C., Deribe, Y. L., Blutt, S. E., Okhuysen, P., Zhang, J., Vilar, E., Nielsen, Ole Haagen, Dupont, A., Younes, M., Patel, K. R., Shroyer, N. F., Rai, K., Estes, M. K., Wang, Y. A., Bertuch, A. A. & DePinho, R. A., 2020, In: Nature Communications. 11, 13 p., 4766.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2019
  41. Published

    Metabonomics in gastroenterology and hepatology

    Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.

    Research output: Contribution to journal › Editorial › Research › peer-review

  42. Published

    Biosimilars for management of Crohn disease

    Nielsen, Ole Haagen & Ainsworth, M. A., 2019, In: Annals of Internal Medicine. 170, 2, p. 129-130 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  43. Published

    Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

    Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Managing vitamin D deficiency in inflammatory bowel disease

    Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Methotrexate for inflammatory bowel disease: time for reconsideration

    Nielsen, Ole Haagen, Ainsworth, M. A. & Steenholdt, Casper, 2019, In: Expert Review of Gastroenterology and Hepatology. 13, 5, p. 407-409 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  46. Published

    Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease

    Gubatan, J., Chou, N. D., Nielsen, Ole Haagen & Moss, A. C., 2019, In: Alimentary Pharmacology and Therapeutics. 50, 11-12, p. 1146-1158 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. 2018
  48. Published

    Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier

    Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

    Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

    Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

    Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

    Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, Bojesen, A. B., Sørensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexoe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., 2018, In: BMJ Open. 8, 2, 15 p., :e018166.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Inflammatory bowel disease with primary sclerosing cholangitis: A Danish population-based cohort study 1977-2011

    Sørensen, J. Ø., Nielsen, Ole Haagen, Andersson, M., Ainsworth, M. A., Ytting, H., Bélard, E. & Jess, T., 2018, In: Liver International. 38, 3, p. 532-541

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD

    Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Rational Management of Iron-Deficiency Anaemia in Inflammatory Bowel Disease

    Nielsen, Ole Haagen, Soendergaard, C., Vikner, M. E. & Weiss, G., 2018, In: Nutrients. 10, 1, 25 p., 82.

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    Role of Vitamin D in the Natural History of Inflammatory Bowel Disease

    Nielsen, Ole Haagen, Rejnmark, L. & Moss, A. C., 2018, In: Journal of Crohn's and Colitis. 12, 6, p. 742-752 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    Targeting JAK-STAT signal transduction in IBD

    Soendergaard, C., Bergenheim, F. H., Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 2018, In: Pharmacology & Therapeutics. 192, p. 100-111

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4947702