Özcan Met

Özcan Met

Visiting associate professor, Gæstelektor

Member of:


    1. 2023
    2. Published

       of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes

      Hulen, T. M., Friese, C., Kristensen, N. P., Granhøj, J. S., Borch, T. H., Peeters, M. J. W., Donia, M., Andersen, Mads Hald, Hadrup, S. R., Svane, Inge Marie & Met, Özcan, 2023, In: Frontiers in Immunology. 14, 15 p., 1180997.

      Research output: Contribution to journalJournal articlepeer-review

    3. Published

      Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy

      Mortensen, R. E. J., Holmström, M. O., Lisle, T. L., Hasselby, Jane Preuss, Willemoe, G. L., Met, Özcan, Svane, Inge Marie, Johansen, Julia Sidenius, Nielsen, Dorte Lisbet, Chen, I. M. & Andersen, Mads Hald, 2023, In: Journal for ImmunoTherapy of Cancer. 11, 3

      Research output: Contribution to journalJournal articlepeer-review

    4. Published

      Restoring tumor immunogenicity with dendritic cell reprogramming

      Zimmermannova, O., Ferreira, A. G., Ascic, E., Santiago, M. V., Kurochkin, I., Hansen, M., Met, Ö., Caiado, I., Shapiro, I. E., Michaux, J., Humbert, M., Soto-Cabrera, D., Benonisson, H., Silvério-Alves, R., Gomez-Jimenez, D., Bernardo, C., Bauden, M., Andersson, R., Höglund, M., Miharada, K. & 9 others, Nakamura, Y., Hugues, S., Greiff, L., Lindstedt, M., Rosa, F. F., Pires, C. F., Bassani-Sternberg, M., Svane, Inge Marie & Pereira, C. F., 2023, In: Science immunology. 8, 85, 20 p., eadd4817.

      Research output: Contribution to journalJournal articlepeer-review

    5. Published

      TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy

      Tvingsholm, S. A., Frej, M. S., Rafa, V. M., Hansen, U. K., Ormhøj, M., Tyron, A., Jensen, A. W. P., Kadivar, M., Bentzen, A. K., Munk, K. K., Aasbjerg, G. N., Ternander, J. S. H., Heeke, C., Tamhane, T., Schmess, C., Funt, S. A., Kjeldsen, J. W., Kverneland, A. H., Met, Ö., Draghi, A. & 4 others, Jakobsen, S. N., Donia, M., Svane, Inge Marie & Hadrup, S. R., 2023, In: Journal for ImmunoTherapy of Cancer. 11, 8, 16 p., e006847.

      Research output: Contribution to journalJournal articlepeer-review

    6. 2022
    7. Published

      Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV

      Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.

      Research output: Contribution to journalJournal articlepeer-review

    8. Published

      Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells

      Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.

      Research output: Contribution to journalJournal articlepeer-review

    9. Published

      Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

      Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, Ho, V. T., Hobbs, G. S., Knudsen, T. A., Skov, V., Kjær, L., Larsen, T. S., Hansen, D. L., Lindsley, R. C., Hasselbalch, Hans Carl, Grauslund, J. H., Lisle, T. L., Met, Özcan, Wilkinson, P., Greenbaum, B., Sepulveda, M. A., Chan, T., Rampal, R., Andersen, Mads Hald, Abdel-Wahab, O., Bhardwaj, N., Wolchok, J. D., Mullally, A. & Merghoub, T., 2022, In: Science Translational Medicine. 14, 649, eaba4380.

      Research output: Contribution to journalJournal articlepeer-review

    10. Published

      Clinical advances and ongoing trials on mRNA vaccines for cancer treatment

      Lorentzen, C. L., Haanen, J. B., Met, Özcan & Svane, Inge Marie, 2022, In: The Lancet Oncology. 23, 10, p. e450-e458

      Research output: Contribution to journalReviewpeer-review

    11. Published

      Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy

      Chamberlain, C. A., Bennett, Eric Paul, Kverneland, Anders Handrup, Svane, Inge Marie, dqp123, dqp123 & Met, Özcan, 2022, In: Molecular Therapy - Oncolytics. 24, p. 417-428 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    12. Published

      Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment

      Bendtsen, S. K., Perez Penco, Maria, Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, Niels, Met, Özcan, Svane, Inge Marie, Madsen, Daniel Hargbøl & Andersen, Mads Hald, 2022, In: OncoImmunology. 11, 1, 2026020.

      Research output: Contribution to journalJournal articlepeer-review

    13. Published

      Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma.

      Rohaan, M. W., Borch, T. H., Van Den Berg, J. H., Met, Ö., Kessels, R., Geukes Foppen, M. H., Stoltenborg Granhøj, J., Nuijen, B., Nijenhuis, C., Jedema, I., Van Zon, M., Scheij, S., Beijnen, J. H., Hansen, M., Voermans, C., Noringriis, I. M., Monberg, T. J., Holmstroem, R. B., Wever, L. D. V., Van Dijk, M. & 37 others, Grijpink-Ongering, L. G., Valkenet, L. H. M., Torres Acosta, A., Karger, M., Borgers, J. S. W., Ten Ham, R. M. T., Retèl, V. P., Van Harten, W. H., Lalezari, F., Van Tinteren, H., Van Der Veldt, A. A. M., Hospers, G. A. P., Stevense-Den Boer, M. A. M., Suijkerbuijk, K. P. M., Aarts, M. J. B., Piersma, D., Van Den Eertwegh, A. J. M., De Groot, J. W. B., Vreugdenhil, G., Kapiteijn, E., Boers-Sonderen, M. J., Fiets, W. E., Van Den Berkmortel, F. W. P. J., Ellebaek, E., Hølmich, Lisbet Rosenkrantz, Van Akkooi, A. C. J., Van Houdt, W. J., Wouters, M. W. J. M., Van Thienen, J. V., Blank, C. U., Meerveld-Eggink, A., Klobuch, S., Wilgenhof, S., Schumacher, T. N., dqp123, dqp123, Svane, Inge Marie & Haanen, J. B. A. G., 2022, In: New England Journal of Medicine. 387, 23, p. 2113-2125 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions

      Granhøj, J. S., Jensen, Agnete Witness Præst, Presti, M., Met, Özcan, Svane, Inge Marie & dqp123, dqp123, 2022, In: Expert Opinion on Biological Therapy. 22, 5, p. 627-641 15 p.

      Research output: Contribution to journalReviewpeer-review

    15. 2021
    16. Published

      Therapeutic Cancer Vaccination With a Peptide Derived From the Calreticulin Exon 9 Mutations Induces Strong Cellular Immune Responses in Patients With CALR-Mutant Chronic Myeloproliferative Neoplasms

      Handlos Grauslund, J., Holmström, M. O., Jørgensen, N. G., Klausen, U., Weis-Banke, S. E., El Fassi, D., Schöllkopf, C., Clausen, M. B., Gjerdrum, L. M. R., Breinholt, M. F., Kjeldsen, J. W., Hansen, M., Koschmieder, S., Chatain, N., Novotny, G. W., Petersen, J., Kjær, L., Skov, V., Met, Ö., Svane, I. M. & 2 others, Hasselbalch, Hans Carl & Andersen, Mads Hald, 26 Feb 2021, In: Frontiers in Oncology. 11, 17 p., 637420.

      Research output: Contribution to journalJournal articlepeer-review

    17. Published

      Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner

      Holmström, M. O., Mortensen, R. E. J., Pavlidis, A. M., Martinenaite, E., Weis-Banke, S. E., Aaboe-Jørgensen, M., Bendtsen, S. K., Met, Özcan, Pedersen, A. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, Feb 2021, In: Cellular and Molecular Immunology. 18, 2, p. 415-426 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors

      Morgan Hulen , T., Chamberlain, C. A., Svane, Inge Marie & Met, Özcan, 2021, In: Immuno. 1, 3, p. 194-211

      Research output: Contribution to journalJournal articlepeer-review

    19. Published

      An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma

      Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, Anne Ortved, Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2021, In: OncoImmunology. 10, 1, 1975889.

      Research output: Contribution to journalJournal articlepeer-review

    20. Published

      Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

      Borch, T. H., Harbst, K., Rana, A. H., Andersen, R., Martinenaite, E., Kongsted, P., Pedersen, M., Nielsen, M., Kjeldsen, J. W., Kverneland, Anders Handrup, Lauss, M., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Jönsson, G., dqp123, dqp123 & Svane, Inge Marie, 2021, In: Journal for ImmunoTherapy of Cancer. 9, 7, 15 p., e00270.

      Research output: Contribution to journalJournal articlepeer-review

    21. Published

      Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules

      Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, Per & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.

      Research output: Contribution to journalJournal articlepeer-review

    22. Published

      Real-time monitoring of mitochondrial respiration in cytokine-differentiated human primary T cells

      Mølgaard, K., Rahbech, A., Met, Özcan, Svane, Inge Marie, thor Straten, Per, Desler, Claus & Peeters, M. J. W., 2021, In: Journal of Visualized Experiments. 176, e62984.

      Research output: Contribution to journalJournal articlepeer-review

    23. Published

      The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma

      Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    24. Published

      Vaccination against pd-l1 with io103 a novel immune modulatory vaccine in basal cell carcinoma: A phase iia study

      Jørgensen, N. G., Kaae, Jeanette, Grauslund, J. H., Met, Özcan, Nielsen, S. L., Pedersen, A. W., Svane, Inge Marie, Ehrnrooth, E., Andersen, Mads Hald, Zachariae, Claus & Skov, Lone, 2021, In: Cancers. 13, 4, p. 1-15 15 p., 911.

      Research output: Contribution to journalJournal articlepeer-review

    25. Published

      Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens

      Holmen Olofsson, G., Idorn, M., Carnaz Simões, A. M., Aehnlich, P., Skadborg, S. K., Noessner, E., Debets, R., Moser, B., Met, Özcan & thor Straten, Per, 2021, In: Frontiers in Immunology. 12, 645131.

      Research output: Contribution to journalJournal articlepeer-review

    26. 2020
    27. Published

      Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

      Kverneland, Anders Handrup, Pedersen, M., Wulff Westergaard, M. C., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: OncoTarget. 11, 22, p. 2092-2105 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer

      Friese, C., Harbst, K., Borch, T. H., Westergaard, M. C. W., Pedersen, M., Kverneland, A., Jönsson, G., dqp123, dqp123, Svane, Inge Marie & Met, Özcan, 2020, In: Scientific Reports. 10, 1, 12 p., 3914.

      Research output: Contribution to journalJournal articlepeer-review

    29. Published

      Future role for adoptive T-cell therapy in checkpoint inhibitor-resistant metastatic melanoma

      Borch, T. H., Andersen, R., Ellebaek, E., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, e000668.

      Research output: Contribution to journalJournal articlepeer-review

    30. Published

      INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

      Bennett, Eric Paul, Petersen, B. L., Johansen, I. E., Niu, Yiyuan, Yang, Zhang, Chamberlain, C. A., Met, Özcan, Wandall, Hans H. & Frödin, Morten, 2020, In: Nucleic Acids Research. 48, 21, p. 11958-11981 24 p.

      Research output: Contribution to journalJournal articlepeer-review

    31. Published

      Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial

      Jørgensen, N. G., Klausen, U., Grauslund, J. H., Helleberg, C., Aagaard, T. G., Do, T. H., Ahmad, S. M., Olsen, L. R., Klausen, T. W., Breinholt, M. F., Hansen, M., Martinenaite, E., Met, Özcan, Svane, Inge Marie, Knudsen, L. M. & Andersen, Mads Hald, 2020, In: Frontiers in Immunology. 11, 11 p., 595035.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      Qualitative analysis of tumor-infiltrating lymphocytes across human tumor types reveals a higher proportion of bystander CD8+ T cells in non-melanoma cancers compared to melanoma

      Gokuldass, A., Draghi, A., Papp, K., Borch, T. H., Nielsen, M., Westergaard, M. C. W., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Özcan, Harbst, K., Lauss, M., Soraggi, S., Csabai, I., Szállási, Z., Jönsson, G., Svane, Inge Marie & dqp123, dqp123, 2020, In: Cancers. 12, 11, p. 1-15 15 p., 3344.

      Research output: Contribution to journalJournal articlepeer-review

    33. Published

      T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road

      Crowther, M. D., Svane, Inge Marie & Met, Özcan, 2020, In: Cells. 9, 7, 18 p., 1588.

      Research output: Contribution to journalReviewpeer-review

    34. Published

      The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines

      Weis-Banke, S. E., Hübbe, M. L., Holmström, M. O., Jørgensen, M. A., Bendtsen, S. K., Martinenaite, E., Carretta, M., Svane, Inge Marie, Ødum, Niels, Pedersen, A. W., Met, Özcan, Madsen, D. H. & Andersen, Mads Hald, 2020, In: OncoImmunology. 9, 1, 16 p., 1771142.

      Research output: Contribution to journalJournal articlepeer-review

    35. 2019
    36. Published

      Principles of adoptive T cell therapy in cancer

      Met, Özcan, Jensen, K. M., Chamberlain, C. A., dqp123, dqp123 & Svane, Inge Marie, 11 Jan 2019, In: Seminars in Immunopathology. 41, 1, p. 49–58

      Research output: Contribution to journalJournal articlepeer-review

    37. Published

      Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

      Hu, T., Buus, T. B., Krejsgaard, T., Nansen, A., Lundholt, B. K., Spee, P., Fredholm, S., Petersen, D. L., Blümel, E., Gluud, M., Monteiro, M. N., Willerslev-Olsen, A., Andersen, M. H., Straten, P. T., Met, Ö., Stolearenco, V., Fogh, H., Gniadecki, R., Nastasi, C., Litman, T. & 3 others, Woetmann, Anders , Gjerdrum, Lise Mette Rahbek & Ødum, Niels, 2019, In: OncoTarget. 10, 47, p. 4894-4906 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    38. Published

      Inflammation induced PD-L1-specific T cells

      Munir, S., Lundsager, M. T., Jørgensen, M. A., Hansen, M., Petersen, T. H., Bonefeld, Charlotte Menne, Friese, C., Met, Özcan, thor Straten, Per & Andersen, Mads Hald, 2019, In: Cell Stress & Chaperones. 3, 10, p. 319-327

      Research output: Contribution to journalJournal articlepeer-review

    39. Published

      MERTK Acts as a costimulatory receptor on human cd8 t cells

      Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & thor Straten, Per, 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    40. Published

      T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients

      Viborg, N., Ramskov, S., Andersen, R. S., Sturm, T., Fugmann, T., Bentzen, A. K., Rafa, V. M., thor Straten, Per, Svane, Inge Marie, Met, Özcan & Hadrup, S. R., 2019, In: OncoImmunology. 8, 12, 11 p., 1663107.

      Research output: Contribution to journalJournal articlepeer-review

    41. Published

      Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells

      Levring, T. B., Kongsbak-Wismann, Martin, Rode, A. K. O., Al-Jaberi, F. A. H., Lopez, D. V., Met, Özcan, Woetmann, Anders , Bonefeld, Charlotte Menne, Ødum, Niels & Geisler, Carsten, 2019, In: Scientific Reports. 9, 13 p., 16725.

      Research output: Contribution to journalJournal articlepeer-review

    42. 2018
    43. Published

      The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy

      Holmstrom, M. O., Martinenaite, E., Ahmad, S. M., Met, Özcan, Friese, C., Kjaer, L., Riley, C. H., thor Straten, Per, Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 1 Feb 2018, In: Leukemia. 32, 2, p. 429-437

      Research output: Contribution to journalJournal articlepeer-review

    44. Published

      Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model

      Idorn, M., Skadborg, S. K., Kellermann, L., Halldórsdóttir, H. R., Holmen Olofsson, G., Met, Özcan & thor Straten, Per, 2018, In: OncoImmunology. 7, 8, 10 p., e1450715.

      Research output: Contribution to journalJournal articlepeer-review

    45. Published

      Frequent adaptive immune responses against arginase-1

      Martinenaite, E., Mortensen, R. E. J., Hansen, M., Orebo Holmström, M., Munir Ahmad, S., Grønne Dahlager Jørgensen, N., Met, Özcan, dqp123, dqp123, Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 3, 9 p., e1404215.

      Research output: Contribution to journalJournal articlepeer-review

    46. Published

      Improved migration of tumor ascites lymphocytes to ovarian cancer microenvironment by CXCR2 transduction

      Idorn, M., Olsen, M., Halldórsdóttir, H. R., Skadborg, S. K., Pedersen, M., Høgdall, Claus Kim, Høgdall, Estrid Vilma Solyom, Met, Özcan & thor Straten, Per, 2018, In: OncoImmunology. 7, 4, 12 p., e1412029.

      Research output: Contribution to journalJournal articlepeer-review

    47. Published

      SATB1 in malignant T cells

      Fredholm, S. M., Willerslev-Olsen, A., Met, Ö., Kubat, L., Gluud, M., Mathiasen, S. L., Friese, C., Blümel, E., Petersen, D. L., Hu, T., Nastasi, C., Lindahl, L. M., Buus, T. B., Krejsgaard, T. F., Wasik, M. A., Kopp, K. L. M., Koralov, S. B., Persson, J. L., Bonefeld, C. M., Geisler, C. & 4 others, Woetmann, Anders , Iversen, L., Becker, J. C. & Ødum, Niels, 2018, In: The Journal of Investigative Dermatology. 138, 8, p. 1805-1815 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    48. Published

      T cells isolated from patients with checkpoint inhibitor-resistant melanoma are functional and can mediate tumor regression

      Andersen, R., Borch, T. H., Draghi, A., Gokuldass, A., Rana, M. A. H., Pedersen, M., Nielsen, M., Kongsted, P., Kjeldsen, J. W., Westergaard, M. C. W., Radic, H. D., Chamberlain, C. A., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Larsen, M. S., Met, Özcan, Svane, Inge Marie & dqp123, dqp123, 2018, In: Annals of Oncology. 29, 7, p. 1575-1581 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    49. Published

      T-cell Responses in the Microenvironment of Primary Renal Cell Carcinoma-Implications for Adoptive Cell Therapy

      Andersen, R., Westergaard, M. C. W., Kjeldsen, J. W., Müller, A., Pedersen, N. W., Hadrup, S. R., Met, Özcan, Seliger, B., Kromann-Andersen, B., Hasselager, T., dqp123, dqp123 & Svane, Inge Marie, 2018, In: Cancer Immunology Research. 6, 2, p. 222-235 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    50. Published

      The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy

      Ahmad, S. M., Martinenaite, E., Holmström, M., Jørgensen, M. A., Met, Özcan, Nastasi, C., Klausen, U., dqp123, dqp123, Pedersen, Lars Møller, Munksgaard, Lars, Ødum, Niels, Woetmann, Anders , Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 2, 10 p., e1390641.

      Research output: Contribution to journalJournal articlepeer-review

    51. 2017
    52. Published

      Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study

      Kongsted, P., Borch, T. H., Ellebaek, E., Iversen, T. Z., Andersen, R., Met, Özcan, Hansen, M., Lindberg, H., Sengeløv, L. & Svane, Inge Marie, 1 Apr 2017, In: Cytotherapy. 19, 4, p. 500-513 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    53. Published

      The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms

      Holmström, M. O., Hjortso, M. D., Ahmad, S. M., Met, Özcan, Martinenaite, E., Riley, C., Straten, P., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2017, In: Leukemia. 31, p. 495-498

      Research output: Contribution to journalLetterpeer-review

    54. 2016
    55. Published

      Therapeutic Vaccination against A Modified Minimal Survivin Epitope Induces Functional CD4 T Cells That Recognize Survivin-Expressing Cells

      Nitschke, N. J., Bjoern, J., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 1 Sep 2016, In: Scandinavian Journal of Immunology. 84, 3, p. 191-193 3 p.

      Research output: Contribution to journalComment/debatepeer-review

    56. Published

      mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma

      Borch, T. H., Engell-Noerregaard, L., Iversen, T. Z., Ellebaek, E., Met, Özcan, Hansen, M., Andersen, Mads Hald, thor Straten, Per & Svane, Inge Marie, 1 Sep 2016, In: OncoImmunology. 5, 9, 12 p., e1207842.

      Research output: Contribution to journalJournal articlepeer-review

    57. Published

      Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21

      Hansen, M., Met, Özcan, Larsen, N. B., Rosenkilde, Mette, Andersen, Mads Hald, Svane, Inge Marie & Hjortø, Gertrud Malene, Sep 2016, In: Cytotherapy. 18, 9, p. 1187-1196

      Research output: Contribution to journalJournal articlepeer-review

    58. Published

      PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine

      Munir Ahmad, S., Martinenaite, E., Hansen, M., Junker, N., Borch, T. H., Met, Özcan, Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2 Aug 2016, In: OncoImmunology. 5, 8, e1202391.

      Research output: Contribution to journalJournal articlepeer-review

    59. Published

      Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen

      Andersen, R., Donia, M., Ellebæk, E., Borch, T. H., Kongsted, P., Iversen, T. Z., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Andersen, Mads Hald, thor Straten, Per & Svane, Inge Marie, Aug 2016, In: Clinical Cancer Research. 22, 15, p. 3734-3745 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    60. Published

      CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment

      Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.

      Research output: Contribution to journalJournal articlepeer-review

    61. Published

      Immune monitoring using mRNA-transfected dendritic cells

      Borch, T. H., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Humana Press, Vol. 1428. p. 245-259 15 p. (Methods in Molecular Biology, Vol. 1428).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    62. Published

      Large-scale mRNA transfection of dendritic cells by electroporation in continuous flow systems

      Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 2016, Methods in Molecular Biology. Humana Press, Vol. 1428. p. 151-161 11 p. (Methods in Molecular Biology, Vol. 1428).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    63. Published

      Transfection of tumor-infiltrating T cells with mRNA encoding CXCR2

      Idorn, M., thor Straten, Per, Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Rhoads, R. E. (ed.). Springer, Vol. 1428. p. 261-276 16 p. (Methods in Molecular Biology, Vol. 1428).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    64. 2015
    65. Published

      Broadening the repertoire of melanoma-associated T-cell epitopes

      Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    66. Published

      Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer

      Hjortsø, M. D., Larsen, S. K., Kongsted, P., Met, Özcan, Frøsig, T. M., Andersen, G. H., Ahmad, S. M., Svane, Inge Marie, Becker, J. C., Straten, P. T. & Andersen, Mads Hald, Jan 2015, In: OncoImmunology. 4, 1, e968480.

      Research output: Contribution to journalJournal articlepeer-review

    67. 2014
    68. Published

      Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor

      Donia, M., Larsen, S. M., Met, Özcan & Svane, Inge Marie, Aug 2014, In: Cytotherapy. 16, 8, p. 1117–1120 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    69. Published

      Spontaneous presence of FOXO3-specific T cells in cancer patients

      Larsen, S. K., Ahmad, S. M., Idorn, M., Met, Özcan, Martinenaite, E., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 1 Jan 2014, In: OncoImmunology. 3, 8, e953411.

      Research output: Contribution to journalJournal articlepeer-review

    70. T-cell responses to oncogenic Merkel cell polyomavirus proteins distinguish patients with Merkel cell carcinoma from healthy donors

      Lyngaa, R., Pedersen, N. W., Schrama, D., Thrue, C. A., Ibrani, D., Met, Özcan, Straten, P., Nghiem, P., Becker, J. C. & Hadrup, S. R., 2014, In: Clinical Cancer Research. 20, 7, p. 1768-1778 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    71. 2013
    72. Published

      In-chip fabrication of free-form 3D constructs for directed cell migration analysis

      Olsen, M. H., Hjortø, Gertrud Malene, Hansen, M., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 21 Dec 2013, In: Lab On a Chip. 13, 24, p. 4800-4809 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    73. Published

      HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

      Munir, S., Andersen, G. H., Met, Özcan, Donia, M., Frøsig, T. M., Larsen, S. K., Klausen, T. W., Svane, Inge Marie & Andersen, Mads Hald, 15 Mar 2013, In: Cancer Research. 73, 6, p. 1764-76 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    74. Published

      Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA

      Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    75. Published

      Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy

      Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    76. Published

      High frequency of T cells specific for cryptic epitopes in melanoma patients

      Andersen, R. S., Andersen, S. R., Hjortsø, M. D., Lyngaa, R., Idorn, M., Køllgård, T. M., Met, Özcan, Straten, P. & Hadrup, S. R., 2013, In: OncoImmunology. 2, 7, e25374.

      Research output: Contribution to journalJournal articlepeer-review

    77. Published

      Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells

      Cathelin, D., Met, Özcan & Svane, Inge Marie, 2013, In: Cytotherapy. 15, 6, p. 740-749 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    78. 2012
    79. Published

      Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

      Ellebaek, E., Iversen, T. Z., Junker, N., Donia, M., Engell-Noerregaard, L., Met, Özcan, Hølmich, Lisbet Rosenkrantz, Andersen, R. S., Hadrup, S. R., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2012, In: Journal of Translational Medicine. 10, p. 169

      Research output: Contribution to journalJournal articlepeer-review

    80. Published

      Cellular based cancer vaccines: type 1 polarization of dendritic cells

      Hansen, M., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.

      Research output: Contribution to journalReviewpeer-review

    81. 2011
    82. Published

      Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip

      Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., Apr 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    83. Published

      Cell culture plastics with immobilized interleukin-4 for monocyte differentiation

      Hansen, M., Hjortø, Gertrud Malene, Met, Özcan, Jakobsen, M. H., Svane, Inge Marie & Larsen, N. B., Feb 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    84. Published

      High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer

      Met, Özcan, Balslev, E., Flyger, H. & Svane, Inge Marie, 1 Jan 2011, In: Breast Cancer Research and Treatment. 125, 2, p. 395-406 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    85. 2009
    86. Published

      Addition of interferon-alpha to a standard maturation cocktail induces CD38 up-regulation and increases dendritic cell function

      Trepiakas, R., Pedersen, Anders Elm, Met, Özcan & Svane, Inge Marie, 2009, In: Vaccine. 27, 16, p. 2213-9 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    87. 2008
    88. Published

      Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential

      Met, Özcan, Eriksen, J. & Svane, Inge Marie, Oct 2008, In: Molecular Biotechnology. 40, 2, p. 151-60 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    89. Published

      Comparison of alpha-Type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocyte-derived dendritic cell preparations from cancer patients.

      Trepiakas, R., Pedersen, Anders Elm, Met, Özcan, Hansen, M. H., Berntsen, A. & Svane, I. M., 2008, In: Vaccine. 26, 23, p. 2824-32 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    90. 2006
    91. Published

      The effect of a therapeutic dendritic cell-based cancer vaccination depends on the blockage of CTLA-4 signaling.

      Met, Özcan, Wang, M., Pedersen, Anders Elm, Nissen, Mogens Holst, Buus, Søren & Claesson, Mogens Helweg, 2006, In: Cancer Letters. 231, 2, p. 247-56 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    92. 2003
    93. Published

      Immunobiological Effects of Glucosamine In Vitro

      Forchhammer, L., Thorn, M., Met, Özcan, Gad, M., Weidner, M. S. & Claesson, Mogens Helweg, 1 Oct 2003, In: Scandinavian Journal of Immunology. 58, 4, p. 404-11 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    94. Published

      Peptide-loaded dendritic cells prime and activate MHC-class I-restricted T cells more efficiently than protein-loaded cross-presenting DC

      Met, Özcan, Buus, Søren & Claesson, Mogens Helweg, 2003, In: Cellular Immunology. 222, 2, p. 126-33 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    ID: 33971757