Niels Høiby

Niels Høiby

Professor, No job title

Member of:

    ORCID: 0000-0002-1347-725X

    Publication year:
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    1 - 100 out of 506Page size: 100
    1. 2024
    2. Published

      Centennial celebrations of the Danish Pasteur Society

      Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3

      Research output: Contribution to journal › Editorial › Research

    3. Published

      Louis Pasteur and the birth of microbiology in Denmark

      Høiby, Niels, 2024, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 132, 1, p. 43-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2023
    5. Published

      Attainment of Target Antibiotic Levels by Oral Treatment of Left-sided Infective Endocarditis: A POET Substudy

      Bock, M., Theut, A. M., van Hasselt, J. G. C., Wang, H., Fuursted, K., Hoiby, N., Lerche, C. J., Ihlemann, N., Gill, S., Christiansen, U., Nielsen, H. L., Lemming, L., Elming, H., Povlsen, J. A., Bruun, N. E., Hofsten, D., Fosbøl, E. L., Kober, L., Schultz, M., Pries-Heje, M. M. & 9 others, Kristensen, J. H., Christensen, J. J., Rosenvinge, F. S., Torp-Pedersen, Christian, Helweg-Larsen, J., Tønder, N., Iversen, Kasper, Bundgård, Henning & Moser, Claus Ernst, 2023, In: Clinical Infectious Diseases. 77, 2, p. 242–251 10 p., 168.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms

      Armengol, E., Kragh, K. N., Tolker-Nielsen, Tim, Sierra, J. M., Higazy, Doaa Mohamed Mohamed E, Ciofu, Oana, Viñas, M. & Høiby, Niels, 2023, In: Antimicrobial Agents and Chemotherapy. 67, 4, e0164122.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Hyperbaric oxygen therapy counteracts Pseudomonas aeruginosa biofilm micro-compartment phenomenon in murine thermal wounds

      Laulund, A. S., Schwartz, F. A., Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 6, 8 p., 100159.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis

      Bock, M., Van Hasselt, J. G. C., Schwartz, F., Wang, H., Høiby, N., Fuursted, K., Ihlemann, N., Gill, S., Christiansen, U., Bruun, N. E., Elming, H., Povlsen, J. A., Køber, L., Høfsten, D. E., Fosbøl, E. L., Pries-Heje, M. M., Christensen, J. J., Rosenvinge, F. S., Torp-Pedersen, C., Helweg-Larsen, J. & 4 others, Tønder, N., Iversen, Kasper, Bundgård, Henning & Moser, Claus Ernst, 2023, In: The Journal of antimicrobial chemotherapy. 78, 12, p. 2840–2848 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. 2022
    11. Published

      Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity

      Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

      Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model

      Schwartz, F. A., Christophersen, L., Thomsen, K., Baekdal, S., Pals Bendixen, M., Jørgensen, M., Bull Rasmussen, I. K., Laulund, A. S., Høiby, Niels & Moser, Claus Ernst, 2022, In: Frontiers in Microbiology. 13, 988386.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections

      Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.

      Research output: Contribution to journal › Review › Research › peer-review

    15. Published

      Dynamics of a Staphylococcus aureus infective endocarditis simulation model

      Schwartz, F. A., Nielsen, L., Struve Andersen, J., Bock, M., Christophersen, L., Sunnerhagen, T., Lerche, C. J., Bay, Lene, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 8, p. 515-523

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo

      Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections

      Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    18. Published

      Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection

      Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.

      Research output: Contribution to journal › Review › Research › peer-review

    19. Published

      Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Høiby, Niels, Svendsen, J. S. M., Stensen, W., Thomsen, K., Cavanagh, J. P. & Moser, Claus Ernst, 2022, In: Journal of Global Antimicrobial Resistance. 29, p. 185-193 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Murine burn lesion model for studying acute and chronic wound infections

      Calum, Henrik Pierre, Trøstrup, H., Laulund, A. S., Thomsen, K., Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 477-490 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

      Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Tolerance and resistance of microbial biofilms

      Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. 621–635

      Research output: Contribution to journal › Review › Research › peer-review

    23. 2021
    24. Published

      Autologous fibrin sealant co-delivered with antibiotics is a robust method for topical antibiotic treatment after sinus surgery

      Aanæs, Kasper, Nielsen, Kim G., Arndal, E., von Buchwald, Christian, Pressler, T. & Høiby, Niels, 1 Feb 2021, In: Acta Oto-Laryngologica. 141, 2, p. 181-186 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model

      Laulund, A. S., Schwartz, F., Trøstrup, H., Thomsen, K., Christophersen, L., Calum, Henrik Pierre, Ciofu, Oana, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 652012.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome

      Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, Kasper, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cell and Developmental Biology. 9, 25 p., 643335.

      Research output: Contribution to journal › Review › Research › peer-review

    27. Published

      Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model

      Thomsen, K., Christophersen, L., Lerche, C. J., Holmgaard, D. B., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2021, In: International Journal of Antimicrobial Agents. 57, 1, 106213.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus

      Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Maintaining normal lung function in children with cystic fibrosis is possible with aggressive treatment regardless of Pseudomonas aeruginosa infections

      Hansen, C. R., Gilljam, M., Olesen, H. V., Høiby, Niels, Karpati, F., Johansson, E., Krantz, C., Skov, M., Pressler, T. & Lindblad, A., 2021, In: Acta Pædiatrica. 110, 9, p. 2607-2609 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Novel human in vitro vegetation simulation model for infective endocarditis

      Schwartz, F. A., Christophersen, L., Laulund, A. S., Lundquist, R., Lerche, C., Rude Nielsen, P., Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: APMIS. 129, 11, p. 653-662 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      SARS-CoV-2 infection dynamics in Denmark, February through October 2020: Nature of the past epidemic and how it may develop in the future

      Rasmussen, S., Petersen, M. S. & Høiby, Niels, 2021, In: PLoS ONE. 16, 4 April, e0249733.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. 2020
    33. Published

      Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients

      Mauch, R. M., Hentschel, J., Aanæs, Kasper, Barucha, A., Nolasco da Silva, M. T., Levy, C. E., Høiby, Niels & Mainz, J. G., 2020, In: Pediatric Pulmonology. 55, 4, p. 959-967

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

      Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Further Commentary

      Hengzhuang, W. & Høiby, Niels, 2020, In: Pediatric Pulmonology. 55, 1, 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    37. Published

      In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments

      Christophersen, L., Schwartz, F. A., Lerche, C. J., Svanekjær, T., Kragh, K. N., Laulund, A. S., Thomsen, K., Henneberg, K. Å., Sams, T., Høiby, Niels & Moser, Claus Ernst, 2020, In: Journal of Cystic Fibrosis. 19, 6, p. 996-1003

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

      Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.

      Research output: Contribution to journal › Letter › Research › peer-review

    39. Published

      Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation

      Schwensen, H. F., Moser, Claus Ernst, Perch, Michael, Pressler, T. & Høiby, Niels, 2020, In: Journal of Cystic Fibrosis. 19, 4, p. 587-594

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance

      Ahmed, M. N., Abdelsamad, A., Wassermann, T., Porse, A., Becker, J., Sommer, M. O. A., Høiby, Niels & Ciofu, Oana, 2020, In: npj Biofilms and Microbiomes. 6, 1, 10 p., 28.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. 2019
    42. Published

      P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions

      Henriksen, K., Rørbo, N., Rybtke, Morten Levin, Martinet, M. G., Tolker-Nielsen, Tim, Høiby, Niels, Middelboe, Mathias & Ciofu, Oana, 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Antibiotic therapy as personalized medicine - general considerations and complicating factors

      Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

      Research output: Contribution to journal › Review › Research › peer-review

    45. Published

      Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test

      Ravnholt, C., Qvist, T., Kolpen, M., Pressler, T., Skov, M. & Høiby, Niels, 2019, In: Journal of Cystic Fibrosis. 18, 4, p. 516-521

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

      Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Editorial comment

      Moser, Claus Ernst, Song, Z. & Høiby, Niels, 2019, In: APMIS. 127, 5, 1 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    48. Published

      Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth

      Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

      Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

      Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections

      Hengzhuang, W., Green, K., Pressler, T., Skov, M., Katzenstein, T. L., Wu, X. & Høiby, Niels, 2019, In: Pediatric Pulmonology. 54, 5, p. 575-580

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients

      Mauch, R. M., Rossi, C. L., Nolasco da Silva, M. T., Bianchi Aiello, T., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2019, In: Medical Microbiology and Immunology. 208, 2, p. 205-213 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. 2018
    55. Published

      Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin

      Ahmed, M. N. A., Porse, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 1 Aug 2018, In: Antimicrobial Agents and Chemotherapy. 62, 8, 12 p., e00320-18.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine

      Schwensen, H. F., Kan, C., Treasure, J., Høiby, Niels & Sjögren, M., 2018, In: Eating and Weight Disorders. 23, 4, p. 399-418

      Research output: Contribution to journal › Review › Research › peer-review

    58. Published

      Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

      Caçador, N. C., Paulino da Costa Capizzani, C., Monteiro Marin Torres, L. A. G., Galetti, R., Ciofu, Oana, Lúcia da Costa Darini, A. & Høiby, Niels, 2018, In: PLoS ONE. 13, 11, 11 p., e0208013.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

      Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis

      Mauch, R. M., Nørregaard, L. L., Ciofu, Oana, Levy, C. E. & Høiby, Niels, 2018, In: Journal of Cystic Fibrosis. 17, 3, p. 356-359

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

      Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152

      Research output: Contribution to journal › Review › Research › peer-review

    62. Published

      Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

      Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Next generation microbiology and cystic fibrosis diagnostics: are we there yet?

      Moser, Claus Ernst, Thomsen, T. R. & Høiby, Niels, 2018, In: Current Opinion in Pulmonary Medicine. 24, 6, p. 599-605

      Research output: Contribution to journal › Review › Research › peer-review

    64. Published

      The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis

      Ravnholt, C., Kolpen, M., Skov, M., Moser, C., Katzenstein, T. L., Pressler, T., Høiby, Niels & Qvist, T., 2018, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 126, 12, p. 885-891 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. 2017
    66. Published

      Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

      Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM

      Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    69. Published

      Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink

      Kirkeby, Svend, Hammer, Anne Sofie Vedsted, Høiby, Niels & Salomonsen, C. M., May 2017, In: International Journal of Pediatric Otorhinolaryngology. 96, p. 156-163 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      A short history of microbial biofilms and biofilm infections

      Høiby, Niels, Apr 2017, In: APMIS. 125, 4, p. 272-275 4 p.

      Research output: Contribution to journal › Review › Research › peer-review

    71. Published

      Biofilms and host response - helpful or harmful

      Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

      Research output: Contribution to journal › Review › Research › peer-review

    72. Published

      Chronic urinary tract infections in patients with spinal cord lesions – biofilm infection with need for long-term antibiotic treatment

      Tofte, N., Nielsen, A. C. Y., Trøstrup, H., Andersen, C. B., Von Linstow, M., Hansen, B., Biering-Sørensen, Fin, Høiby, Niels & Moser, Claus Ernst, Apr 2017, In: APMIS. 125, 4, p. 385-391 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    73. Published

      Diagnosis of biofilm infections in cystic fibrosis patients

      Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.

      Research output: Contribution to journal › Review › Research › peer-review

    74. Published

      Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients

      Schultz, A. N. Ø., Høiby, Niels, Nielsen, X. C., Pressler, T., Dalhoff, Kim, Duno, M., Buchard, Anders, Johansen, H. K., Wang, H. & Dalbøge, C. S., Mar 2017, In: Pediatric Pulmonology. 52, 3, p. 319-323 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment

      Fernandez-Barat, L., Ciofu, Oana, Kragh, K. N., Pressler, T., Johansen, U., Motos, A., Torres, A. & Høiby, Niels, Mar 2017, In: Journal of Cystic Fibrosis. 16, 2, p. 222-229

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

      Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis

      Qvist, T., Pressler, T., Katzenstein, T. L., Høiby, Niels & Collins, M. T., Jan 2017, In: Pediatric Pulmonology. 52, 1, p. 34-40 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

      Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis

      Mauch, R. M., Rossi, C. L., Aiello, T. B., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2017, In: Pathogens and Disease. 75, 6, 4 p., ftx069.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review

      Møller, M. E., Alanin, M. C., Grønhøj, C., Aanæs, Kasper, Høiby, Niels & von Buchwald, Christian, 2017, In: American Journal of Rhinology and Allergy. 31, 5, p. 293-298 6 p.

      Research output: Contribution to journal › Review › Research › peer-review

    82. 2016
    83. Published

      The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms

      Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus

      Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

      Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

      Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

      Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Diffusion retardation by binding of tobramycin in an alginate biofilm model

      Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits

      Møller-Sørensen, H., Korshin, A., Mogensen, T. & Høiby, Niels, Apr 2016, In: Journal of Hospital Infection. 92, 4, p. 337-339 3 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    90. Published

      Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Animal models of chronic wound care: the application of biofilms in clinical research

      Trøstrup, H., Thomsen, K., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2016, In: Chronic Wound Care Management and Research. 3, p. 123-132 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    93. Published

      Bacterial evolution in PCD and CF patients follows the same mutational steps

      Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis

      Moser, Claus Ernst, Hartvig, T., Schierbeck, J. & Høiby, Niels, 2016, In: Ugeskrift for Laeger. 178, p. 2-6 5 p., V05150426.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Genome sequence of Pseudomonas aeruginosa strain DK1-NH57388A, a stable mucoid cystic fibrosis isolate

      Norman, A., Ciofu, Oana, Amador, C. I., Høiby, Niels & Jelsbak, L., 2016, In: Genome Announcements. 4, 1, e00008-16.

      Research output: Contribution to journal › Journal article › Research

    96. Published

      Kai Adolf Jensen, professor i almindelig patologi

      Høiby, Niels, 2016, In: Bibliotek for Laeger. 208, 4, p. 344-361

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model

      Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

      Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    99. Published

      Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis

      Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      The phagocytic fitness of leucopatches may impact the healing of chronic wounds

      Thomsen, K., Trøstrup, H., Christophersen, L., Lundquist, R., Høiby, Niels & Moser, Claus Ernst, 2016, In: Clinical and Experimental Immunology. 184, 3, p. 368-77 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    101. 2015
    102. Published

      Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    103. Published

      A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

      Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

      Research output: Contribution to journal › Journal article › Research › peer-review

    104. Published

      Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection

      Qvist, T., Eickhardt-Dalbøge, S. R., Kragh, K. N., Andersen, C. B., Iversen, M., Høiby, Niels & Bjarnsholt, Thomas, Dec 2015, In: European Respiratory Journal. 46, 6, p. 1823-1826 4 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    105. Published

      The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface

      Rybtke, Morten Levin, Berthelsen, J., Yang, L., Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, Dec 2015, In: MicrobiologyOpen. 4, 6, p. 917-930 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    106. Published

      RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT

      Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    107. Published

      Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    108. Published

      Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

      Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    109. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    110. Published

      The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

      Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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