Niels Erik Møllegaard
Associate Professor
Transcription, RNA, and Gene Medicine Program
Blegdamsvej 3, 2200 København N., 18 Bygning 18, Building: 18-2-28
Member of:
- 2020
- Published
UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
Leinisch, F., Mariotti, M., Andersen, S. H., Lindemose, Søren, Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael J., 2020, In: Scientific Reports. 10, 1, 11 p., 3106.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins
Traynor, S., Møllegaard, Niels Erik, Jørgensen, M. G., Brückmann, N. H., Pedersen, C. B., Terp, M. G., Johansen, S., Dejardin, J., Ditzel, H. J. & Gjerstorff, M. F., 2019, In: Nucleic Acids Research. 47, 13, p. 6668-6684 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Uranyl Photocleavage of Phosphopeptides Yields Truncated C-Terminally Amidated Peptide Products
Elnegaard, R. L. B., Møllegaard, Niels Erik, Zhang, Q., Kjeldsen, F. & Jørgensen, T. J. D., 19 Jun 2017, In: ChemBioChem. 18, 12, p. 1117-1122 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Barley plants over-expressing the NAC transcription factor gene HvNAC005 show stunting and delay in development combined with early senescence
Christiansen, M. W., Matthewman, C., Podzimska-Sroka, D. A., O'Shea, Charlotte, Lindemose, Søren, Møllegaard, Niels Erik, Holme, I. B., Hebelstrup, K., Skriver, Karen & Gregersen, P. L., 2016, In: Journal of Experimental Botany. 67, 17, p. 5259-5273 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression
Gjerstorff, M. F., Relster, M. M., Greve, K. B. V., Moeller, J. B., Elias, D., Lindgreen, J. N., Schmidt, S., Mollenhauer, J., Voldborg, B., Pedersen, C. B., Brückmann, N. H., Møllegaard, Niels Erik & Ditzel, H. J., 13 Oct 2014, In: Nucleic Acids Research. 42, 18, p. 11433-46 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Indirect Sequence Readout Component in the E. coli Cyclic AMP Receptor Protein Operator
Lindemose, Søren, Nielsen, Peter E., Valentin-Hansen, P. & Møllegaard, Niels Erik, 21 Mar 2014, In: ACS chemical biology. 9, 3, p. 752-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Phosphorylation Tag for Uranyl Mediated Protein Purification and Photo Assisted Tag Removal
Zhang, Q., Jørgensen, T. J. D., Nielsen, Peter E. & Møllegaard, Niels Erik, 2014, In: PloS one. 9, 3, p. 1-6 6 p., e91138.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors
Welner, D. H., Lindemose, Søren, Grossmann, J. G., Møllegaard, Niels Erik, Olsen, A. N., Helgstrand, C., Skriver, Karen & Lo Leggio, Leila, 2012, In: Biochemical Journal. 444, p. 395-404 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GAGE cancer-germline antigens are recruited to the nuclear envelope by germ cell-less (GCL)
Gjerstorff, M., Rösner, Heike Ilona, Pedersen, C. B., Greve, K. B. V., Schmidt, S., Wilson, K. L., Mollenhauer, J., Besir, H., Poulsen, F. M., Møllegaard, Niels Erik & Ditzel, H., 2012, In: P L o S One. 7, 9, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
A DNA minor groove electronegative potential genome map based on photo-chemical probing
Lindemose, Søren, Nielsen, Peter E., Hansen, M. & Møllegaard, Niels Erik, 1 Aug 2011, In: Nucleic Acids Research. 39, 14, p. 6269-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Dissecting direct and indirect readout of cAMP receptor protein DNA binding using an inosine and 2,6-diaminopurine in vitro selection system.
Lindemose, Søren, Nielsen, Peter E. & Møllegaard, Niels Erik, 2008, In: Nucleic Acids Research. 36, 14, p. 4797-807 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphate Selective Uranyl Photo-Affinity Cleavage of Proteins. Determination of Phosphorylation Sites.
Kristensen, L. H., Nielsen, Peter E., Jørgensen, C. I., Kragelund, Birthe Brandt & Møllegaard, Niels Erik, 2008, In: ChemBioChem. 9, 15, p. 2377-81 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Polyamines preferentially interact with bent adenine tracts in double-stranded DNA
Lindemose, Søren, Nielsen, Peter E. & Møllegaard, Niels Erik, 2005, In: Nucleic Acids Research. 33, 6, p. 1790-803 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uranyl photoprobing of nonbent A/T- and bent A-tracts. A difference of flexibility?
Møllegaard, Niels Erik, Lindemose, Søren & Nielsen, Peter E., 2005, In: Biochemistry. 44, 21, p. 7855-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Increased Temperature and 2-Methyl-2,4-pentanediol Change the dna Stucture of both Curved and Uncurved Adenine/Thymine-Rich Sequences
Møllegaard, Niels Erik & Nielsen, Peter E., 2003, In: Biochemistry. Vol. 42, p. 8587-8593Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased temperature and 2-methyl-2,4-pentanediol change the DNA structure of both curved and uncurved adenine/thymine-rich sequences
Møllegaard, Niels Erik & Nielsen, Peter E., 2003, In: Biochemistry. 42, 28, p. 8587-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
In vitro Transcription from Peptide Nucleic Acid/DNA Strand Displacement Loops
Møllegaard, Niels Erik & Nielsen, Peter E., 2002, Peptide Nucleic Acids. Totowa, New Jersey: Humana Press, p. 249-258Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- 2000
- Published
Applications of Uranyl Cleavage Mapping of RNA Structure
Møllegaard, Niels Erik & Nielsen, Peter E., 2000, RNA-Ligand Interactions. Part B. Molecular Biology Methods. Methods in Enzymology. Vol. 318. Academic Press, p. 43-47Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- Published
Quinoxaline antibiotics enhance peptide nucleic acid binding to double-stranded DNA
Møllegaard, Niels Erik, Bailly, C., Waring, M. J. & Nielsen, Peter E., 2000, In: Biochemistry. 39, 31, p. 9502-9507Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Helical periodicity of (PNA)2-(DNA)triplexes in strand displacement complexes
Kim, J., Kim, K., Møllegaard, Niels Erik, Nielsen, Peter E. & Koo, H., 1999, In: Nucleic Acids Research. 27,14, p. 2842-2847Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA folding and misfolding of the hammerhead ribozyme
Møllegaard, Niels Erik, Murchie, A. I. & Lilley, D. M. J., 1999, In: Biochemistry. 16; 38 (11), p. 3345-3354Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Effects of diaminopurine and inosine substitutions on A-tract induced DNA curvature. Importance of the 3'-Atract junction
Møllegaard, Niels Erik, Bailly, C., Waring, M. J. & Nielsen, Peter E., 1997, In: Nucleic Acids Research. 25, 17, p. 3497-3502Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence/structure selective thermal and photochemical cleavage of yeast-tRNA(Phe) by UO(2)2+
Nielsen, Peter E. & Møllegaard, Niels Erik, 1997, In: Journal of Molecular Recognition. 9, 3, p. 228-32 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uranyl photoprobing of DNA structures and drug-DNA complexes
Møllegaard, Niels Erik & Nielsen, Peter E., 1997, Drug-DNA Interaction Protocols. Humana Press, p. 43-49 (Methods in Molecular Biology, Vol. 90).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 1995
- Published
Ionic interactions and the global conformations of the hammerhead ribozyme
Bassi, G. S., Møllegaard, Niels Erik, Murchie, A. I., von Kitzing, E. & Lilley, D. M., 1995, In: Nature Structural and Molecular Biology. 2, 1, p. 45-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of the 2-amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA
Bailly, C., Møllegaard, Niels Erik & Nielsen, P. E., 1995, In: EMBO Journal. 14, No 9, p. 2121-2131Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters
Møllegaard, Niels Erik, Buchardt, O. & Nielsen, Peter E., 26 Apr 1994, In: Proceedings of the National Academy of Sciences of the United States of America. 91, 9, p. 3892-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uranyl photoprobing of a four-way DNA junction: evidence for specific metal ion binding
Møllegaard, Niels Erik, Murchie, A. I., Lilley, D. M. & Nielsen, Peter E., 1 Apr 1994, In: E M B O Journal. 13, 7, p. 1508-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide nucleic acid. DNA strand displacement loops as artificial transcription promotors
Møllegaard, Niels Erik, Buchardt, O., Egholm, M. & Nielsen, P. E., 1994, In: Proceedings of the National Academy of Science of the United States of America. 91, p. 3892-3895Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Characterization of Promotor recognition Complexes formed by CRP and CytR for Repression and by CRP and RNA Polymerase for Activation of Transcription on the Escherichia coli deoP2 Promoter
Møllegaard, Niels Erik, Rasmussen, P. B., Valentin-Hansen, P. B. & Nielsen, Peter E., 1993, In: Journal of Biological Chemistry. 268, 23, p. 17471-17477Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
Uranyl photoprobing of conformational changes in DNA induced by drug binding
Nielsen, Peter E., Møllegaard, Niels Erik & Jeppesen, C., Feb 1990, In: Anti-Cancer Drug Design. 5, 1, p. 105-10 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA conformational analysis in solution by uranyl mediated photocleavage
Nielsen, Peter E., Møllegaard, Niels Erik & Jeppesen, C., 1990, In: Nucleic Acids Research. 18, 13, p. 3847-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tandem DNA-bound cAMP-CRP complexes are required for transcriptional repression of the deoP2 promoter by the CytR repressor in Escherichia coli
Søgaard-Andersen, L., Møllegaard, Niels Erik, Douthwaite, S. R. & Valentin-Hansen, P., 1990, In: Molecular Microbiology. 4, 9, p. 1595-601 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CytR repressor antagonizes cyclic AMP-cyclic AMP receptor protein activation of the deoCp2 promoter of Escherichia coli K-12
Søgaard-Andersen, L., Martinussen, J., Møllegaard, Niels Erik, Douthwaite, S. R. & Valentin-Hansen, P., 1990, In: Journal of Bacteriology. 172, 10, p. 5706-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uranyl photoprobing of conformational changes in DNA induced by drug binding
Nielsen, P. E., Møllegaard, Niels Erik & Jeppesen, C., 1990, In: Oncology Research. 5, p. 105-110Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8025
Most downloads
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767
downloads
GAGE cancer-germline antigens are recruited to the nuclear envelope by germ cell-less (GCL)
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
146
downloads
Uranyl Photocleavage of Phosphopeptides Yields Truncated C-Terminally Amidated Peptide Products
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
49
downloads
Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins
Research output: Contribution to journal › Journal article › Research › peer-review
Published