Nicole Schmitt

Nicole Schmitt

Professor with special responsibilities


  1. 2020
  2. Published

    A Novel Loss-of-Function Variant in the Chloride Ion Channel Gene Clcn2 Associates with Atrial Fibrillation

    Hansen, T. H., Yan, Yannan, Ahlberg, G., Vad, O. B., Refsgaard, L., Louro Larupa dos Santos, Joana, Mutsaers, N., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, 29 Jan 2020, In : Scientific Reports. 10, 1, 10 p., 1453.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Functional phenotype variations of two novel Kv 7.1 mutations identified in patients with Long QT syndrome

    Hammami Bomholtz, S., Refaat, M., Steffensen, Annette Buur, David, J., Espinosa, K., Nussbaum, R., Wojciak, J., Bentzen, Bo Hjorth, Scheinman, M. & Schmitt, Nicole, 2020, In : Pacing and Clinical Electrophysiology. 43, 2, p. 210-216 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Investigating gene-microRNA networks in atrial fibrillation patients with mitral valve regurgitation

    Louro Larupa dos Santos, Joana, Rodriguez Palomo, Ismael, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, 2020, In : PLoS ONE. 15, 5, 21 p., e0232719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2019
  6. Published

    Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular KV currents and predisposes to ventricular arrhythmia

    David, J., Lisewski, U., Crump, S. M., Jepps, Thomas Andrew Qvistgaard, Bocksteins, E., Wilck, N., Lossie, J., Roepke, T. K., Schmitt, Nicole & Abbott, G. W., Feb 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 2, p. 2537-2552 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Reappraisal of variants previously linked with sudden infant death syndrome: results from three population-based cohorts

    Paludan-Mueller, C., Ghouse, J., Vad, O. B., Herfelt, C. B., Lundegaard, Pia Rengtved, Ahlberg, G., Schmitt, Nicole, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2019, In : European Journal of Human Genetics. 27, 9, p. 1427-1435

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2018
  9. Published

    Homozygosity for SCN4A Arg1142Gln causes congenital myopathy with variable disease expression

    Sloth, C. K., Denti, F., Schmitt, Nicole, Bentzen, Bo Hjorth, Fagerberg, C., Vissing, John & Gaist, D., Oct 2018, In : Neurology: Genetics. 4, 5, p. e267 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Functional consequences of genetic variation in sodium channel modifiers in early onset lone atrial fibrillation

    Denti, F., Paludan-Müller, C., Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, Mar 2018, In : Personalized Medicine. 15, 2, p. 93-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    SUMO co-expression modifies KV 11.1 channel activity

    Steffensen, Annette Buur, Andersen, M. N., Mutsaers, N., Mujezinovic, A. & Schmitt, Nicole, Mar 2018, In : Acta Physiologica (Print). 222, 3, 11 p., e12974.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Multiple genetic variations in sodium channel subunits in a case of sudden infant death syndrome

    Denti, F., Bentzen, Bo Hjorth, Wojciak, J., Thomsen, N. M., Scheinman, M. & Schmitt, Nicole, 2018, In : Pacing and Clinical Electrophysiology. 41, 6, p. 620-626

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

    Steffensen, Annette Buur, Bomholtz, S. H., Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In : Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Spinal dorsal horn astrocytes release GABA in response to synaptic activation

    Christensen, R. K., Delgado-Lezama, R., Russo, R. E., Lind, Barbara Lykke, Alcocer, E. L., Rath, Martin Fredensborg, Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V., Carlsen, Eva Maria Meier & Perrier, Jean-Francois Marie, 2018, In : The Journal of Physiology. 596, 20, p. 4983-4994 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    Trafficking of Kv2.1 Channels to the Axon Initial Segment by a Novel Nonconventional Secretory Pathway

    Jensen, C. S., Watanabe, S., Stas, J. I., Klaphaak, J., Yamane, A., Schmitt, Nicole, Olesen, Søren-Peter, Trimmer, J. S., Rasmussen, Hanne Borger & Misonou, H., 29 Nov 2017, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 37, 48, p. 11523-11536 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants

    Gregers, E., Ahlberg, G., Christensen, T., Jabbari, J., Larsen, K. O., Herfelt, C. B., Henningsen, K. M., Andreasen, L., Thiis, J. J., Lund, J., Holme, S., Haunsø, Stig, Bentzen, Bo Hjorth, Schmitt, Nicole, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, Oct 2017, In : Heart Rhythm. 14, 10, p. 1531-1538

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis

    Colman, M. A., Ni, H., Liang, Bo, Schmitt, Nicole & Zhang, H., Jun 2017, In : PLoS Computational Biology. 13, 6, 21 p., e1005587.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2016
  20. Published

    Structural interplay of Kv7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (Kv7.1-A287T)

    Rothenberg, I., Piccini, I., Wrobel, E., Stallmeyer, B., Müller, J., Greber, B., Strutz-Seebohm, N., Schulze-Bahr, E., Schmitt, Nicole & Seebohm, G., Nov 2016, In : HeartRhythm Case Reports. 2, 6, p. 521-529 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The anticonvulsant retigabine suppresses neuronal Kv2-mediated currents

    Stas, J. I., Bocksteins, E., Jensen, C. S., Schmitt, Nicole & Snyders, D. J., 13 Oct 2016, In : Scientific Reports. 6, 12 p., 35080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size

    Christensen, A. H., Chatelain, F. C., Huttner, I. G., Olesen, Morten Steen Salling, Soka, M., Feliciangeli, S., Horvat, C., Santiago, C. F., Vandenberg, J. I., Schmitt, Nicole, Olesen, Søren-Peter, Lesage, F. & Fatkin, D., Aug 2016, In : Journal of Molecular and Cellular Cardiology. 97, p. 24-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, Mark, Jepps, Thomas Andrew Qvistgaard, Bomholtz, S. H., Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In : Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Iron Overload Leading to Torsades de Pointes in β-Thalassemia and Long QT Syndrome

    Refaat, M. M., El Hage, L., Steffensen, Annette Buur, Hotait, M., Schmitt, Nicole, Scheinman, M. & Badhwar, N., Mar 2016, In : Cardiac Electrophysiology Clinics. 8, 1, p. 247-256 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes

    Liin, S. I., Karlsson, U., Bentzen, Bo Hjorth, Schmitt, Nicole & Elinder, F., 23 Feb 2016, In : Acta Physiologica (Print). 218, 1, p. 28-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2015
  27. Published

    Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking

    Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In : American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels

    David, J., Stas, J. I., Schmitt, Nicole & Bocksteins, E., 5 Aug 2015, In : Scientific Reports. 5, p. 1-14 14 p., 12813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Astrocytes gate synaptic transmission from unmyelinated sensory afferents

    Perrier, Jean-Francois Marie, Christensen, R. K., Delgado-Lezama, R., Russo, R., Lind, Barbara Lykke, Alcocer, E. L., Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V. & Carlsen, E. M., Aug 2015, In : Glia. 63, S1, p. E241-E241 T08-22B .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells

    Adinolfi, B., Carpi, S., Romanini, A., Da Pozzo, E., Castagna, M., Costa, B., Martini, C., Olesen, Søren-Peter, Schmitt, Nicole, Breschi, M. C., Nieri, P. & Fogli, S., Jul 2015, In : Anticancer Research. 35, 7, p. 3781-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance

    Steffensen, Annette Buur, Refaat, M. M., David, J., Mujezinovic, A., Callø, Kirstine, Wojciak, J., Nussbaum, R. L., Scheinman, M. M. & Schmitt, Nicole, 12 Jun 2015, In : Scientific Reports. 5, p. 1-13 13 p., 10009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel

    Liin, S. I., Silverå Ejneby, M., Barro-Soria, R., Skarsfeldt, Mark, Larsson, J. E., Starck Härlin, F., Parkkari, T., Bentzen, Bo Hjorth, Schmitt, Nicole, Larsson, H. P. & Elinder, F., 5 May 2015, In : Proceedings of the National Academy of Science of the United States of America. 112, 18, p. 5714–5719 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    IKs Gain- and Loss-of-Function In Early-Onset Lone Atrial Fibrillation

    Steffensen, Annette Buur, Refsgaard, L., Andersen, M. N., Vallet, C., Mujezinovic, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Olesen, Morten Steen Salling & Schmitt, Nicole, 2015, In : Journal of cardiovascular electrophysiology. 26, 7, p. 715-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2014
  35. Published

    Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanning

    Eckey, K., Wrobel, E., Strutz-Seebohm, N., Pott, L., Schmitt, Nicole & Seebohm, G., 15 Aug 2014, In : The Journal of Biological Chemistry. 289, 33, p. 22749-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    From pan-reactive KV7 channel opener to subtype selective opener/inhibitor by addition of a methyl group

    Blom, S. M., Rottländer, M., Kehler, J., Bundgaard, C., Schmitt, Nicole & Jensen, H. S., Jun 2014, In : PloS one. 9, 6, 9 p., e100209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

    Schmitt, Nicole, Grunnet, M. & Olesen, Søren-Peter, Apr 2014, In : Physiological Reviews. 94, 2, p. 609-53 45 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

    Nielsen, J. B., Bentzen, Bo Hjorth, Olesen, Morten Steen Salling, David, J., Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, Apr 2014, In : Biomarkers in Medicine. 8, 4, p. 557-570 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Brugada syndrome risk loci seem protective against atrial fibrillation

    Andreasen, L., Nielsen, J. B., Darkner, S., Christophersen, I. E., Jabbari, J., Refsgaard, L., Thiis, J. J., Sajadieh, Ahmad, Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Schmitt, Nicole & Olesen, Morten Steen Salling, 26 Mar 2014, In : European Journal of Human Genetics. 22, p. 1357-1361 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Specific Sorting and Post-Golgi trafficking of Dendritic Potassium Channels in Living Neurons

    Jensen, C. S., Watanabe, S., Rasmussen, Hanne Borger, Schmitt, Nicole, Olesen, Søren-Peter, Frost, N. A., Blanpied, T. A. & Misonou, H., 25 Feb 2014, In : The Journal of Biological Chemistry. 289, p. 10566-10581 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

    Yuan, L., Koivumaki, J., Liang, Bo, Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In : American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation

    Olesen, Morten Steen Salling, Andreasen, L., Jabbari, J., Refsgaard, L., Haunsø, Stig, Olesen, Søren-Peter, Nielsen, J. B., Schmitt, Nicole & Svendsen, Jesper Hastrup, Feb 2014, In : Heart Rhythm. 11, 2, p. 246-251 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Fast detection of extrasynaptic GABA with a whole-cell sniffer

    Christensen, R. K., Petersen, A. V., Schmitt, Nicole & Perrier, Jean-Francois Marie, 2014, In : Frontiers in Cellular Neuroscience. 8, p. 1-9 9 p., 00133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2013
  45. Published

    Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

    Liang, Bo, Soka, M., Christensen, A. H., Olesen, Morten Steen Salling, Larsen, A. P., Knop, Filip Krag, Wang, F., Nielsen, J. B., Andersen, M. N., Humphreys, D., Mann, S. A., Huttner, I. G., Vandenberg, J. I., Svendsen, Jesper Hastrup, Haunsø, Stig, Preiss, T., Seebohm, G., Olesen, Søren-Peter, Schmitt, Nicole & Fatkin, D., 27 Dec 2013, In : Journal of Molecular and Cellular Cardiology. 67, p. 69-76 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Genetic Modifier of the QTc Interval Associated With Early-Onset Atrial Fibrillation

    Andreasen, L., Nielsen, J. B., Christophersen, I. E., Holst, A. G., Sajadieh, Ahmad, Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Schmitt, Nicole & Olesen, Morten Steen Salling, Oct 2013, In : Canadian Journal of Cardiology. 29, 10, p. 1234-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia

    Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, Iain Andrew & Olesen, Søren-Peter, 30 Sep 2013, In : Hypertension. 62, 6, p. 1090-1097 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    A Common Structural Component for β-Subunit Mediated Modulation of Slow Inactivation in Different KV Channels

    Strutz-Seebohm, N., Henrion, U., Schmitt, Nicole, Schulze-Bahr, E. & Seebohm, G., 26 Jun 2013, In : Cellular Physiology and Biochemistry. 31, 6, p. 968-980 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

    Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In : Science Signaling. 6, 278, p. rs11 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Trafficking of the IKs -Complex in MDCK Cells: Site of Subunit Assembly and Determinants of Polarized Localization

    David, J., Andersen, M. N., Olesen, Søren-Peter, Rasmussen, Hanne Borger & Schmitt, Nicole, Apr 2013, In : Traffic. 14, 4, p. 399-411 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

    Olesen, Morten Steen Salling, Refsgaard, L., Holst, A. G., Larsen, A. P., Grubb, Søren, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Schmitt, Nicole & Callø, Kirstine, 2013, In : Cardiovascular Research. 98, 3, p. 488-495 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Characterization and mechanisms of action of novel NaV1.5 channel mutations associated with Brugada syndrome

    Callø, Kirstine, Refaat, M. M., Grubb, Søren, Wojciak, J., Campagna, J., Thomsen, N. M., Nussbaum, R. L., Scheinman, M. M. & Schmitt, Nicole, 2013, In : Circulation. Arrhythmia and Electrophysiology (Online). 6, 1, p. 177-184 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Dysfunction of the heteromeric KV7.3/KV7.5 potassium channel is associated with autism spectrum disorders

    Nielsen, Mette Gilling, Rasmussen, Hanne Borger, Callø, Kirstine, F. Sequeira, A., Baretto, M., Oliveira, G., Almeida, J., B. Lauritsen, M., Ullmann, R., Boonen, S. E., Brøndum-Nielsen, K., M. Kalscheuer, V., Tümer, Asuman Zeynep, M. Vicente, A., Schmitt, Nicole & Tommerup, Niels, 2013, In : Frontiers in Genetics. 4, 54, p. 1-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Gliadin Fragments and a Specific Gliadin 33-mer Peptide Close KATP Channels and Induce Insulin Secretion in INS-1E Cells and Rat Islets of Langerhans

    Dall, M., Callø, Kirstine, Haupt-Jorgensen, M., Larsen, J., Schmitt, Nicole, Josefsen, K. & Buschard, Karsten Stig, 2013, In : PLOS ONE. 8, 6, p. 1-10 10 p., e66474.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2012
  56. Published

    Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

    Christophersen, I. E., Olesen, M. S., Liang, Bo, Andersen, M. N., Larsen, A. P., Nielsen, J. B., Haunsø, Stig, Olesen, Søren-Peter, Tveit, A., Svendsen, Jesper Hastrup & Schmitt, Nicole, 21 Dec 2012, In : European Heart Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Cellular mechanisms for presynaptic inhibition of sensory afferents

    Christensen, R. K., Delgado-Lezama, R., russo, R., lind, B., Schmitt, Nicole, LOEZA-ALCOCER, M., Lauritzen, Martin & Perrier, Jean-Francois Marie, 2012. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  58. Published

    High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

    Olesen, M. S., Yuan, L., Liang, Bo, Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In : Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

    Olesen, M. S., Bentzen, Bo Hjorth, Nielsen, J. B., Steffensen, Annette Buur, David, J., Jabbari, J., Jensen, H., Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, 2012, In : B M C Medical Genetics. 13, p. 24

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. 2011
  61. Published

    A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

    Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In : Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Cellular mechanisms for presynaptic inhibition of sensory afferents.

    Perrier, Jean-Francois Marie, delgado-lezama, R., Christensen, R. K., Lind, B., Schmitt, Nicole, Loeza-Alcocer, E., petersen, A., Lauritzen, Martin & russo, R., 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  63. Published

    Letter by Olesen et al regarding article, "MOG1: a new susceptibility gene for Brugada syndrome"

    Olesen, M. S., Holst, A. G. & Schmitt, Nicole, 2011, In : Circulation: Cardiovascular Genetics. 4, 5

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

    Calloe, K., Schmitt, Nicole, Grubb, Søren, Pfeiffer, R., David, J., Kanter, R., Cordeiro, J. M., Antzelevitch, C. & Callø, Kirstine, 2011, In : Canadian Journal of Physiology and Pharmacology. 89, 10, p. 723-36 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

    Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, Bo, Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In : Cardiovascular Research. 89, 4, p. 786-793 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. 2010
  67. Published

    Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2

    Cordeiro, J. M., Perez, G. J., Schmitt, Nicole, Pfeiffer, R., Nesterenko, V. V., Burashnikov, E., Veltmann, C., Borggrefe, M., Wolpert, C., Schimpf, R. & Antzelevitch, C., Dec 2010, In : Canadian Journal of Physiology and Pharmacology. 88, 12, p. 1181-90 10 p.

    Research output: Contribution to journalJournal articleResearch

  68. Published

    Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2

    Lundby, Alicia, Jespersen, T., Schmitt, Nicole, Grunnet, M., Olesen, S., Cordeiro, J. M. & Calloe, K., Aug 2010, In : British Journal of Pharmacology. 160, 8, p. 2028-44 17 p.

    Research output: Contribution to journalJournal articleResearch

  69. Published

    Differential effects of ICA-27243 on cloned K(V)7 channels

    Blom, S. M., Schmitt, Nicole & Jensen, H. S., Jan 2010, In : Pharmacology. 86, 3, p. 174-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Structural basis for KV7.1/KCNEx interactions in the IKs channel complex

    Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In : Heart Rhythm. 7, 5, p. 708-713

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. 2009
  72. Published

    Functional properties of human neuronal Kv11 channels

    Einarsen, K., Callø, Kirstine, Grunnet, M., Olesen, Søren-Peter & Schmitt, Nicole, 2009, In : Pflügers Archiv: European Journal of Physiology. 458, 4, p. 689-700 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Phosphorylation of connexin43 on serine 306 regulates electrical coupling

    Procida, Kristina, Jørgensen, L., Schmitt, Nicole, Delmar, M., Taffet, S. M., Holstein-Rathlou, N., Nielsen, Morten Schak & Braunstein, T. H., 2009, In : Heart Rhythm. 6, 11, p. 1632-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    The acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytes

    Blom, S. M., Schmitt, Nicole & Jensen, H. S., 2009, In : PLoS ONE. 4, 12, p. e8251

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. 2008
  76. Published

    KCNE3 mutation V17M identified in a patient with lone atrial fibrillation.

    Lundby, Alicia, Ravn, L. S., Svendsen, J. H., Hauns, S., Olesen, Søren-Peter & Schmitt, Nicole, 2008, In : Cellular Physiology and Biochemistry. 21, 1-3, p. 47-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. 2007
  78. Published

    Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

    Callø, Kirstine, Ravn, L. S., Schmitt, Nicole, Sui, J. L., Duno, M., Haunso, S., Grunnet, M., Svendsen, J. H. & Olesen, Søren-Peter, 2007, In : Biochemical and Biophysical Research Communications. 364, 4, p. 889-95 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes.

    Callø, Kirstine, Nielsen, Morten Schak, Grunnet, M., Schmitt, Nicole & Jorgensen, N. K., 2007, In : BBA General Subjects. 1773, 6, p. 764-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.

    Lundby, Alicia, Ravn, L. S., Svendsen, Jesper Hastrup, Olesen, Søren-Peter & Schmitt, Nicole, 2007, In : Heart Rhythm. 4, 12, p. 1532-41 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Modulation of ERG channels by XE991.

    Elmedyb, P., Callø, Kirstine, Schmitt, Nicole, Hansen, R. S., Grunnet, M. & Olesen, Søren-Peter, 2007, In : Basic & Clinical Pharmacology & Toxicology. 100, 5, p. 316-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.

    Nielsen, N. H., Winkel, B. G., Kanters, Jørgen K., Schmitt, Nicole, Hofman-Bang, J., Jensen, H. S., Bentzen, Bo Hjorth, Sigurd, B., Larsen, Lars Allan, Andersen, P. S., Kjeldsen, K., Grunnet, M., Christiansen, M., Olesen, Søren-Peter & Haunsø, Stig, 2007, In : Biochemical and Biophysical Research Communications. 354, 3, p. 776-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

    Rasmussen, Hanne Borger, Frøkjaer-Jensen, C., Jensen, C. S., Jensen, H. S., Jørgensen, N. K., Misonou, H., Trimmer, J. S., Olesen, Søren-Peter & Schmitt, Nicole, 2007, In : Journal of Cell Science. 120, Pt 6, p. 953-63 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

    Schmitt, Nicole, Callø, Kirstine, Nielsen, N. H., Buschmann, M., Speckmann, E., Schulze-Bahr, E. & Schwarz, M., 2007, In : Biochemical and Biophysical Research Communications. 358, 1, p. 304-10 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. 2006
  86. Published

    Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations.

    Shamgar, L., Ma, L., Schmitt, Nicole, Haitin, Y., Peretz, A., Wiener, R., Hirsch, J., Pongs, O. & Attali, B., 2006, In : Circulation Research. 98, 8, p. 1055-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Long QT 1 mutation KCNQ1A344V increases local anesthetic sensitivity of the slowly activating delayed rectifier potassium current.

    Siebrands, C. C., Binder, S., Eckhoff, U., Schmitt, Nicole & Friederich, P., 2006, In : Anesthesiology. 105, 3, p. 511-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

    Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, M. & Olesen, Søren-Peter, 2006, In : Neuropharmacology. 51, 6, p. 1068-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. 2005
  90. Published

    Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.

    Grunnet, M., Behr, E. R., Callø, Kirstine, Hofman-Bang, J., Till, J., Christiansen, M., McKenna, W. J., Olesen, Søren-Peter & Schmitt, Nicole, 2005, In : Heart Rhythm. 2, 11, p. 1238-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Local anesthetic interaction with human ether-a-go-go-related gene (HERG) channels: role of aromatic amino acids Y652 and F656.

    Siebrands, C. C., Schmitt, Nicole & Friederich, P., 2005, In : Anesthesiology. 103, 1, p. 102-12 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. 2003
  93. Published

    KCNQ1 channels sense small changes in cell volume.

    Grunnet, M., Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In : Journal of Physiology. 549, Pt 2, p. 419-27 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. 2000
  95. Published

    A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly.

    Schmitt, Nicole, Schwarz, M., Peretz, A., Abitbol, I., Attali, B. & Pongs, O., 2000, In : EMBO Journal. 19, 3, p. 332-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5624