Nanna MacAulay

Nanna MacAulay

Professor


  1. 2024
  2. Published

    Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

    Westgate, C. S. J., Kamp-Jensen, C., Israelsen, I. M. E., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C. A., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rigmor Højland & Eftekhari, S., 2024, In: British Journal of Pharmacology. 181, 1, p. 70-86

    Research output: Contribution to journalJournal articlepeer-review

  3. Published
  4. Published

    Toward New AQP4 Inhibitors: ORI-TRN-002

    Thormann, M., Traube, N., Yehia, N., Koestler, R., Galabova, G., MacAulay, Nanna & Toft-Bertelsen, Trine Lisberg, 2024, In: International Journal of Molecular Sciences. 25, 2, 11 p., 924.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2023
  6. Published

    Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis

    Razzaghi Khamesi, P., Charitatos, V., Heerfordt, E. K., MacAulay, Nanna & Kurtcuoglu, V., 2023, In: Fluids and Barriers of the CNS. 20, 1, 13 p., 18.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    CSF hypersecretion versus impaired CSF absorption in posthemorrhagic hydrocephalus: a systematic review

    Ben-Shoshan, Shai David, Lolansen, Sara Diana, Mathiesen, Tiit Illimar & MacAulay, Nanna, 2023, In: Acta Neurochirurgica. 165, p. 3271-3287 17 p.

    Research output: Contribution to journalReviewpeer-review

  8. Published

    Day–night fluctuations in choroid plexus transcriptomics and cerebrospinal fluid metabolomics

    Edelbo, Beatriche Louise, Andreassen, Søren Norge, Steffensen, Annette Buur & MacAulay, Nanna, 2023, In: PNAS Nexus. 2, 8, 10 p., pgad262.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Differential proteomic profile of lumbar and ventricular cerebrospinal fluid

    Rostgaard, Nina, Olsen, M. H., Ottenheijm, Maud Eline, Drici, L., Simonsen, A. H., Plomgaard, Peter Stendahl, Gredal, Hanne Birgit, Poulsen, Helle Harding, Zetterberg, H., Blennow, K., Hasselbalch, Steen, MacAulay, Nanna & Juhler, Marianne, 2023, In: Fluids and Barriers of the CNS. 20, 1, 13 p., 6.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Distinct Cerebrospinal Fluid Lipid Signature in Patients with Subarachnoid Hemorrhage-Induced Hydrocephalus

    Toft-Bertelsen, Trine Lisberg, Andreassen, Søren Norge, Rostgaard, Nina, Olsen, M. H., Norager, N. H., Capion, T., Juhler, Marianne & MacAulay, Nanna, 2023, In: Biomedicines. 11, 9, 14 p., 2360.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Dual function of the choroid plexus: Cerebrospinal fluid production and control of brain ion homeostasis

    MacAulay, Nanna & Toft-Bertelsen, Trine Lisberg, 2023, In: Cell Calcium. 116, 9 p., 102797.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Inflammatory Markers as Predictors of Shunt Dependency and Functional Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage

    Rostgaard, Nina, Olsen, M. H., Capion, T., MacAulay, Nanna & Juhler, Marianne, 2023, In: Biomedicines. 11, 4, 14 p., 997.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

    Wardman, Jonathan Henry, Jensen, Mette Nyholm, Andreassen, Søren Norge, Styrishave, Bjarne, Wilhjelm, J. E., Sinclair, A. J. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 44.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Nocturnal increase in cerebrospinal fluid secretion as a circadian regulator of intracranial pressure

    Steffensen, Annette Buur, Edelbo, Beatriche Louise, Barbuskaite, Dagne, Andreassen, Søren Norge, Olsen, M. H., Møller, Kirsten & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 14 p., 49.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Posthemorrhagic Hydrocephalus in Patients with Subarachnoid Hemorrhage Occurs Independently of CSF Osmolality

    Lolansen, Sara Diana, Rostgaard, Nina, Capion, T., Norager, N. H., Olsen, M. H., Juhler, Marianne, Mathiesen, Tiit Illimar & MacAulay, Nanna, 2023, In: International Journal of Molecular Sciences. 24, 14, 13 p., 11476.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Spontaneously hypertensive rats can become hydrocephalic despite undisturbed secretion and drainage of cerebrospinal fluid

    Lolansen, Sara Diana, Barbuskaite, Dagne, Ye, F., Xiang, J., Keep, R. F. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 11 p., 53.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Ventricular CSF proteomic profiles and predictors of surgical treatment outcome in chronic hydrocephalus

    Rostgaard, Nina, Olsen, M. H., Lolansen, Sara Diana, Nørager, N. H., Plomgaard, Peter Stendahl, MacAulay, Nanna & Juhler, Marianne, 2023, In: Acta Neurochirurgica. 165, p. 4059–4070 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. 2022
  19. Published

    Acetazolamide modulates intracranial pressure directly by its action on the cerebrospinal fluid secretion apparatus

    Barbuskaite, Dagne, Ørnbo, E. K., Wardman, Jonathan Henry, Toft-Bertelsen, Trine Lisberg, Conti, E., Andreassen, Søren Norge, Gerkau, N. J., Rose, C. R. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, p. 53 1 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Cerebrospinal fluid osmolality cannot predict development or surgical outcome of idiopathic normal pressure hydrocephalus

    Ørnbo, E. K., Steffensen, Annette Buur, Gredal, Hanne Birgit, Poulsen, Helle Harding, Rostgaard, Nina, Rasmussen, C. H., Møller-Nissen, M., Simonsen, A. H., Hasselbalch, Steen, Juhler, Marianne & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 9 p., 52.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited

    MacAulay, Nanna, Keep, R. F. & Zeuthen, Thomas, 2022, In: Fluids and Barriers of the CNS. 19, 1, 18 p., 26.

    Research output: Contribution to journalReviewpeer-review

  22. Published

    DRAIN - Double-blind Randomized Acetazolamide trial in Idiopathic Normal pressure hydrocephalus

    Virhammar, J., Braun, M., Ekblom, M., Fasth, O., Fallmar, D., Laurell, K., MacAulay, Nanna & Nyholm, D., 2022, In: Fluids and Barriers of the CNS. 19, Supplement 1, p. 10 2 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  23. Published

    Hydrocephalus Study Design: Testing New Hypotheses in Clinical Studies and Bench-to-Bedside Research

    Juhler, Marianne, Hansen, T. S., Novrup, H. V. G., MacAulay, Nanna & Munch, Tina Nørgaard, 2022, In: World Neurosurgery. 161, p. 424-431 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Involvement of Aquaporin-1 in brain water homeostasis

    Jensen, Dennis Bo, Barbuskaite, Dagne & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, Supplement 1, p. 25 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  25. Published

    Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1

    Toft-Bertelsen, Trine Lisberg, Barbuskaite, Dagne, Heerfordt, E. K., Lolansen, Sara Diana, Andreassen, Søren Norge, Rostgaard, Nina, Olsen, M. H., Norager, N. H., Capion, T., Rath, Martin Fredensborg, Juhler, Marianne & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p., 69.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure

    Oernbo, E. K., Steffensen, Annette Buur, Khamesi, P. R., Toft-Bertelsen, Trine Lisberg, Barbuskaite, Dagne, Vilhardt, Frederik, Gerkau, N. J., Tritsaris, Katerina, Simonsen, A. H., Lolansen, Sara Diana, Andreassen, Søren Norge, Hasselbalch, Steen, Zeuthen, Thomas, Rose, C. R., Kurtcuoglu, V. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 25 p., 65.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters

    Lolansen, Sara Diana, Rostgaard, Nina, Barbuskaite, Dagne, Capion, T., Olsen, M. H., Norager, N. H., Vilhardt, Frederik, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Ye, F., Juhler, Marianne, Keep, R. F. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 62.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion

    Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rasmus Herlo Beenfeldt & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.

    Research output: Contribution to journalConference abstract in journalpeer-review

  29. Published

    Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus

    Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Villadsen, René & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 44.

    Research output: Contribution to journalJournal articlepeer-review

  30. 2021
  31. Published
  32. Published

    Inflammatory Markers in Cerebrospinal Fluid from Patients with Hydrocephalus: A Systematic Literature Review

    Lolansen, Sara Diana, Rostgaard, N., Oernbo, E. K., Juhler, Marianne, Simonsen, A. H. & MacAulay, Nanna, 2021, In: Disease Markers. 2021, 12 p., 8834822.

    Research output: Contribution to journalReviewpeer-review

  33. Published

    Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

    Lakk, M., Hoffmann, G. F., Gorusupudi, A., Enyong, E., Lin, A., Bernstein, P. S., Toft-Bertelsen, Trine Lisberg, MacAulay, Nanna, Elliott, M. H. & Krizaj, D., 2021, In: Journal of Lipid Research. 62, 15 p., 100145.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Molecular mechanisms of brain water transport

    MacAulay, Nanna, 2021, In: Nature Reviews Neuroscience. 22, p. 326–344 19 p.

    Research output: Contribution to journalReviewpeer-review

  35. Published

    Reply to 'Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis'

    MacAulay, Nanna, 2021, In: Nature Reviews Neuroscience. 22, p. 651–652

    Research output: Contribution to journalLetterpeer-review

  36. Published

    TRPing on Cell Swelling-TRPV4 Senses It

    Toft-Bertelsen, Trine Lisberg & MacAulay, Nanna, 2021, In: Frontiers in Immunology. 12, 9 p., 730982.

    Research output: Contribution to journalReviewpeer-review

  37. Published

    TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel

    Toft-Bertelsen, Trine Lisberg & MacAulay, Nanna, 2021, In: Cells. 10, 1, 16 p., 165.

    Research output: Contribution to journalReviewpeer-review

  38. 2020
  39. Published

    ARDD 2020: from aging mechanisms to interventions

    Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor

    Toft-Bertelsen, Trine Lisberg, Larsen, B. R., Christensen, S. K., Khandelia, H., Waagepetersen, Helle S. & MacAulay, Nanna, 2020, In: Glia. 69, 1, p. 28-41 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    CrossTalk opposing view: NKCC1 in the luminal membrane of choroid plexus is outwardly directed under basal conditions and contributes directly to cerebrospinal fluid secretion

    MacAulay, Nanna & Rose, C. R., 2020, In: Journal of Physiology. 598, 21, p. 4737-4739 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  42. Published

    Molecular mechanisms of K+ clearance and extracellular space shrinkage—Glia cells as the stars

    MacAulay, Nanna, 2020, In: Glia. 68, 11, p. 2192-2211 20 p.

    Research output: Contribution to journalReviewpeer-review

  43. Published

    Molecular mechanisms of brain water transport

    MacAulay, Nanna, 2020, University of Copenhagen. 222 p.

    Research output: Book/ReportDoctoral thesis

  44. Published

    Pannexin 1 activation and inhibition is permeant-selective

    Nielsen, B. S., Toft-Bertelsen, Trine Lisberg, Lolansen, Sara Diana, Anderson, C. L., Nielsen, Morten Schak, Thompson, R. J. & MacAulay, Nanna, 2020, In: The Journal of Physiology. 598, 2, p. 361-379 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Rebuttal from Nanna MacAulay and Christine R. Rose

    MacAulay, Nanna & Rose, C. R., 2020, In: Journal of Physiology. 598, 21, p. 4743 1 p.

    Research output: Contribution to journalComment/debatepeer-review

  46. 2019
  47. Published

    Developmental maturation of activity-induced K+ and pH transients and the associated extracellular space dynamics in the rat hippocampus

    Larsen, B. R., Stoica, A. & MacAulay, Nanna, 2019, In: Journal of Physiology. 597, 2, p. 583-597

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Evaluating the involvement of cerebral microvascular endothelial Na+/K+-ATPase and Na+-K+-2Cl- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration

    Lykke, K., Assentoft, M., Hørlyck, S., Helms, H. C. C., Stoica, A., Toft-Bertelsen, Trine Lisberg, Tritsaris, Katerina, Vilhardt, Frederik, Larsen, Birger Brodin & MacAulay, Nanna, 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 3, p. 497-512

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Structural determinants underlying permeant discrimination of the Cx43 hemichannel

    Nielsen, B. S., Zonta, F., Farkas, T., Litman, Thomas, Nielsen, Morten Schak & MacAulay, Nanna, 2019, In: Journal of Biological Chemistry. 294, 45, p. 16789-16803 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain

    Toft-Bertelsen, Trine Lisberg, Yarishkin, O., Redmon, S., Phuong, T. T. T., Krizaj, D. & MacAulay, Nanna, 2019, In: Journal of Biological Chemistry. 294, 48, p. 18421-18434 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. 2018
  52. Published

    Corrigendum to “Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's antiseizure efficacy” [Neuropharmacology 143 (2018) 186–204](S0028390818306774)(10.1016/j.neuropharm.2018.09.025)

    Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Hansen, Kasper Lykke, Toft-Bertelsen, Trine Lisberg, Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, Nanna, Kaila, K. & Löscher, W., Dec 2018, In: Neuropharmacology. 143, p. 349-350 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  53. Published

    A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance

    Berland, S., Toft-Bertelsen, Trine Lisberg, Aukrust, I., Byska, J., Vaudel, M., Bindoff, L. A., MacAulay, Nanna & Houge, G., 2018, In: Cold Spring Harbor molecular case studies. 4, 1, 10 p., a002303.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B

    Hampel, P., Römermann, K., MacAulay, Nanna & Löscher, W., 2018, In: Scientific Reports. 8, 11 p., 9877.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy

    Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Lykke, K., Toft-Bertelsen, Trine Lisberg, Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, Nanna, Kaila, K. & Löscher, W., 2018, In: Neuropharmacology. 143, p. 186-204 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Cerebral influx of Na+ and Cl- as the osmotherapy-mediated rebound response in rats

    Oernbo, E. K., Lykke, K., Steffensen, Annette Buur, Töllner, K., Kruuse, Christina Rostrup, Rath, Martin Fredensborg, Löscher, W. & MacAulay, Nanna, 2018, In: Fluids and Barriers of the CNS. 15, 14 p., 27.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Cotransporter-mediated water transport underlying cerebrospinal fluid formation

    Steffensen, Annette Buur, Oernbo, E. K., Stoica, A., Gerkau, N. J., Barbuskaite, Dagne, Tritsaris, Katerina, Rose, C. R. & MacAulay, Nanna, 2018, In: Nature Communications. 9, 1, 13 p., 2167.

    Research output: Contribution to journalJournal articlepeer-review

Previous 1 2 3 Next

ID: 10786