Morten Heiberg Bestle

Morten Heiberg Bestle

Clinical Professor

Member of:

  • Anaesthesiology


Publication year:
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1 - 50 out of 119Page size: 50
  1. 2024
  2. Published

    Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL)

    on behalf of the REVIVAL investigators, O. B. O. T. R. I., Jan 2024, In: Intensive Care Medicine. 50, 1, p. 68-78 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Furosemide versus placebo for fluid overload in intensive care patients-The randomised GODIF trial second version: Statistical analysis plan

    Wichmann, S., Lange, T., Perner, A., Gluud, C., Itenov, T. S., Berthelsen, R. E., Nebrich, L., Wiis, J., Brøchner, A. C., Nielsen, L. G., Behzadi, M. T., Damgaard, K., Andreasen, A. S., Strand, K., Järvisalo, M., Strøm, T., Eschen, C. T., Vang, M. L., Hildebrandt, T., Andersen, F. H. & 14 others, Sigurdsson, M. I., Thomar, K. M., Thygesen, S. K., Troelsen, T. T., Uusalo, P., Jalkanen, V., Illum, D., Sølling, C., Keus, F., Pfortmueller, C. A., Wahlin, R. R., Ostermann, M., Aneman, A. & Bestle, Morten Heiberg, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 130-136 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Heterogeneity of treatment effect of higher dose dexamethasone by geographic region (Europe vs. India) in patients with COVID-19 and severe hypoxemia – a post hoc evaluation of the COVID STEROID 2 trial

    Tirupakuzhi Vijayaraghavan, B. K., Granholm, A., Munch, M. W., Kjær, M. B. N., Møller, M. H., Perner, A., Myatra, S. N., Jha, V., Jha, V., Jha, V., Hammond, N., Micallef, S., Venkatesh, B., Hammond, N., Lange, T., Munch, M. W., Myatra, S. N., Tirupakuzhi Vijayaraghavan, B. K., Saseedharan, S., Benfield, T. & 31 others, Wahlin, R. R., Rasmussen, B. S., Andreasen, Anne Sofie, Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brøchner, A. C., Bestle, Morten Heiberg, Helleberg, Marie, Michelsen, J., Padmanaban, A., Bose, N., Møller, A., Borawake, K., Kristiansen, Klaus Tjelle, Shukla, U., Chew, M. S., Ulrik, Charlotte Suppli, Kjær, M. B. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Gluud, C., Lange, Theis, Marcussen, Klaus Vennick, Nielsen, H., Jensen, T. S., Perner, Anders & the COVID-STEROID 2 collaborators, T. C. 2. C., 2024, In: The Lancet Regional Health - Southeast Asia. 20, 8 p., 100293.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    LASSO regression shows histidine and sphingosine 1 phosphate are linked to both sepsis mortality and endothelial damage

    Jo­hans­son, Pär In­ge­mar , Henriksen, H. H., Karvelsson, S. T., Rolfsson, Ó., Schønemann-Lund, M., Bestle, Morten Heiberg & McGarrity, S., 2024, In: European Journal of Medical Research. 29, 1, 14 p., 71.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium

    Mortensen, C. B., Andersen-Ranberg, N. C., Poulsen, L. M., Granholm, A., Rasmussen, B. S., Kjær, M. B. N., Lange, T., Ebdrup, B. H., Collet, M. O., Andreasen, A. S., Bestle, M. H., Uslu, B., Pedersen, H. S., Nielsen, L. G., Hästbacka, J., Jensen, T. B., Damgaard, K., Sommer, T., Morgen, M., Dey, N. & 6 others, Citerio, G., Estrup, S., Egerod, Ingrid Eugenie, Samuelson, K., Perner, Anders & Mathiesen, Ole, 2024, In: Intensive Care Medicine. 50, p. 103–113 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial

    Nielsen, F. M., Klitgaard, T. L., Siegemund, M., Laake, J. H., Thormar, K. M., Cole, J. M., Aagaard, S. R., Bunzel, A-M. G., Vestergaard, S. R., Langhoff, P. K., Pedersen, C. H., Hejlesen, J. Ø., Abdelhamid, S., Dietz, A., Gebhard, C. E., Zellweger, N., Hollinger, A., Poulsen, L. M., Weihe, S., Andersen-Ranberg, N. C. & 25 others, Pedersen, U. G., Mathiesen, O., Andreasen, Anne Sofie, Brix, H., Thomsen, J. J., Petersen, C. H., Bestle, Morten Heiberg, Wichmann, S., Lund, M. S., Mortensen, K. M., Brand, B. A., Haase, N., Iversen, S. A., Marcussen, Klaus Vennick, Brøchner, A. C., Borup, M., Grøfte, T., Hildebrandt, T., Kjær, M. N., Engstrøm, J., Lange, Theis, Perner, Anders, Schjørring, O. L., Rasmussen, B. S. & HOT-COVID Trial Group, H. T. G., 2024, In: JAMA. 331, 14, p. 1185-1194 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2023
  9. Published

    Atrial Fibrillation (AFIB) in the ICU: Incidence, Risk Factors, and Outcomes: The International AFIB-ICU Cohort Study

    Wetterslev, M., Hylander Møller, M., Granholm, A., Hassager, C., Haase, N., Lange, T., Myatra, S. N., Hästbacka, J., Arabi, Y. M., Shen, J., Cronhjort, M., Lindqvist, E., Aneman, A., Young, P. J., Szczeklik, W., Siegemund, M., Koster, T., Aslam, T. N., Bestle, M. H., Girkov, M. S. & 31 others, Kalvit, K., Mohanty, R., Mascarenhas, J., Pattnaik, M., Vergis, S., Haranath, S. P., Shah, M., Joshi, Z., Wilkman, E., Reinikainen, M., Lehto, P., Jalkanen, V., Pulkkinen, A., An, Y., Wang, G., Huang, L., Huang, B., Liu, W., Gao, H., Dou, L., Li, S., Yang, W., Tegnell, E., Perner, Anders, Poulsen, L. M., Hildebrandt, T., Andreasen, Anne Sofie, Kristiansen, Klaus Tjelle, Mohr, T., Møller, Kirsten & the AFIB-ICU collaborators, T. A. C., 2023, In: Critical Care Medicine. 51, 9, p. 1124-1137 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Bioimpedance and Duration of Organ Dysfunction in Septic Shock - A Prospective Observational Study

    Koch, E. B., Madsen, J. M., Wichmann, S., Bestle, Morten Heiberg & Itenov, Theis Skovsgaard, 2023, In: Journal of Intensive Care Medicine. 38, 10, p. 966-974

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Bioimpedance as a measure of fluids in patients with septic shock. A prospective observational study

    Madsen, J. M., Itenov, Theis Skovsgaard, Koch, E. B. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 3, p. 319-328

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Clinical progression, disease severity, and mortality among adults hospitalized with COVID-19 caused by the Omicron and Delta SARS-CoV-2 variants: A population-based, matched cohort study

    Harboe, Z. B., Roed, C., Holler, J. G., Khan, F. I., Abdulrahman, A. N. A., Mulverstedt, S. L., Lindgaard-Jensen, B., Bertelsen, B. B., Søborg, C., Nielsen, T. L., Hansen, L. V., Madsen, B. L., Browatzki, A., Eiberg, M., Bernhard, P. H., Pedersen, E. M. J., Egelund, G. B., Dungu, A. M., Sejdic, A., Mathiesen, I. H. M. & 56 others, Jespersen, N. Z., Petersen, P. T., Nielsen, L., Jepsen, M. P. G., Pedersen, T. I., Eriksson, R., Seitz-Rasmussen, H. E. S., Bestle, Morten Heiberg, Andersen, H., Skram, U., Skøtt, M. R., Altaraihi, S., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Bagge, K., Jørgensen, K. M., Knudsen, M. J. S., Leineweber, T., Schneider, Uffe Vest, Ahlstrom, M. G., Rytter, S., Le Dous, N., Ravn, P., Reiter, N., Podlekareva, D., Knudsen, A., Johnsen, Stine, Kristensen, Lars Erik Vølund, Leding, C., Hertz, B. B., Benfield, Thomas, Kirk, Ole, Holler, J. G., Ostrowski, Sisse Rye, Sigurdsson, S. T., Perner, Anders, Kirkby, N., Pedersen, M. S., Van Wijhe, M., Simonsen, L., Bager, P. M., Krause, T. G., Voldstedlund, M., Christiansen, L. E., Stegger, M., Cohen, A., Fonager, J., Fomsgaard, A., Legarth, R., Rasmussen, M., Gubbels, S., Wohlfahrt, J., Lillebaek, Troels, Johannesen, C. K., Van Wijhe, M. & Fischer, Thea Kølsen, 2023, In: PLoS ONE. 18, 4 , 15 p., e0282806.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Exhaled nitric oxide in intubated ICU patients on mechanical ventilation—a feasibility study

    Kofoed, A., Hindborg, M., Hjembæk-Brandt, J., Sørensen, C. D., Kolpen, Mette & Bestle, Morten Heiberg, 2023, In: Journal of Breath Research. 17, 4, 6 p., 046014.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Existing Data Sources in Clinical Epidemiology: Database of Community Acquired Infections Requiring Hospital Referral in Eastern Denmark (DCAIED) 2018–2021

    Holler, J. G., Jensen , Jens-Ulrik Stæhr , Engsig, F. N., Bestle, Morten Heiberg, Lindegaard, Birgitte, Rasmussen, J. H., Bundgård, Henning, Nielsen, F. E., Iversen, Kasper, Larsen, J. J., Holzknecht, Barbara Juliane, Boel, J., Sivapalan, P. & Itenov, Theis Skovsgaard, 2023, In: Clinical Epidemiology. 15, p. 939-955 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Goal-directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A randomised, blinded trial (GODIF trial—First version)

    Wichmann, S., Schønemann-Lund, M., Perner, Anders, Itenov, Theis Skovsgaard, Lange, Theis, Gluud, C., Berthelsen, R. E., Brøchner, A. C., Wiis, J. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 470-478 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID–ICU trial

    Andersen-Ranberg, N. C., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M., Citerio, G., Collet, Marie Oxenbøll, Weber, S. O., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2023, In: Intensive Care Medicine. 49, p. 411–420 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    How nurses use National Early Warning Score and Individual Early Warning Score to support their patient risk assessment practice: A fieldwork study

    Langkjaer, C. S., Bundgaard, K., Bunkenborg, G., Nielsen, P. B., Iversen, Kasper, Bestle, Morten Heiberg & Bove, D. G., 2023, In: Journal of Advanced Nursing. 79, 2, p. 789-797 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock

    Kjær, M. B. N., Meyhoff, T. S., Sivapalan, P., Granholm, A., Hjortrup, P. B., Madsen, M. B., Møller, M. H., Egerod, I., Wetterslev, J., Lange, T., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Ostermann, M., Gould, D., Cecconi, M., Malbrain, M. L. N. G., Ahlstedt, C., Kiel, L. B. & 41 others, Bestle, Morten Heiberg, Nebrich, L., Hildebrandt, T., Russell, Lene, Vang, M., Rasmussen, M. L., Sølling, C., Brøchner, A. C., Krag, M., Pfortmueller, C., Kriz, M., Siegemund, M., Albano, G., Aagaard, S. R., Bundgaard, H., Crone, V., Wichmann, S., Johnstad, B., Martin, Y. K., Seidel, P., Mårtensson, J., Hollenberg, J., Wistrand, M., Donati, A., Barbara, E., Karvunidis, T., Hollinger, A., Carsetti, A., Lumlertgul, N., Joelsson-Alm, E., Lambiris, N., Aslam, T. N., Friberg, F. F., Vesterlund, G. K., Mortensen, C. B., Vestergaard, S. R., Caspersen, S. F., Jensen, D. B., Borup, M., Rasmussen, B. S. & Perner, Anders, 2023, In: Intensive Care Medicine. 49, p. 820–830 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Mild induced hypothermia and coagulation and platelet function in patients with septic shock: Secondary outcome of a randomized trial

    Itenov, Theis Skovsgaard, Kromann, M. E., Ostrowski, Sisse Rye, Bestle, Morten Heiberg, Mohr, T., Gyldensted, L., Lindhardt, A., Thormar, K., Sessler, D. I., Juffermans, N. P., Lundgren, Jens & Jensen , Jens-Ulrik Stæhr , 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 909-917 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Novel subgroups in acute respiratory failure based on the trajectories of three endotheliopathy biomarkers: A cohort study

    Schønemann-Lund, M., Itenov, Theis Skovsgaard, Larsson, J. E., Lindegaard, Birgitte, Jo­hans­son, Pär In­ge­mar & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 896-908 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    PaCO2 trajectories in mechanically ventilated patients with COVID-19: A population-based cohort study

    Berg, R. M. G., Ronit, A., Haase, N., Moller, M. H., Kristiansen, K. T. T., Jonassen, T., Wamberg, C., Andreasen, A. S., Mohr, T., Bestle, M. H. H., Jorgensen, V. L. L., Hammer, N. R. R., Mitchell, A. U. U., Smitt, M., Greve, A. M., Nyeland, M. E., Jensen, B. W., Andreasen, A. H., Petersen, J., Solem, E. J. & 2 others, Winther-Jensen, M. & Plovsing, R. R. R., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 779-787 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial

    François, B., Lambden, S., Fivez, T., Gibot, S., Derive, M., Grouin, J-M., Salcedo-Magguilli, M., Lemarié, J., De Schryver, N., Jalkanen, V., Hicheur, T., Garaud, J-J., Cuvier, V., Ferrer, R., Bestle, M., Pettilä, V., Mira, J-P., Bouisse, C., Mercier, E., Vermassen, J. & 6 others, Huberlant, V., Vinatier, I., Anguel, N., Levy, M., Laterre, P. F. & ASTONISH investigators, A. I., 2023, In: The Lancet Respiratory Medicine. 11, 10, p. 894-904 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Pupillary dilation velocity is reduced in intensive care unit patients with septic shock

    Uhrenholt, S., Linér, S. M., Stokholm, J., Christensen, T. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 56-62 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury

    Pickkers, P., Angus, D. C., Arend, J., Bellomo, R., Van Den Berg, E., Bernholz, J., Bestle, M., Broglio, K., Carlsen, J., Doig, C. J., Ferrer, R., Joannidis, M., Francois, B., Doi, K., Kellum, J. A., Laterre, P. F., Liu, K., Mehta, R. L., Murray, P. T., Ostermann, M. & 5 others, Pettilä, V., Richards, S., Young, P., Zarbock, A. & Kjølbye, A. L., 2023, In: BMJ Open. 13, 4, e065613.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The clinical task force: Improving quality of medical students’ internship

    Baker, J. J., Weis, Nina, Boysen, T., Bestle, Morten Heiberg, Andersen, A. G., Morcke, A. M. & Bremholm, L., 2023, In: Heliyon. 9, 2, 9 p., e13419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)

    Anthon, C. T., Pène, F., Perner, A., Azoulay, E., Puxty, K., Van De Louw, A., Barratt-Due, A., Chawla, S., Castro, P., Póvoa, P., Coelho, L., Metaxa, V., Kochanek, M., Liebregts, T., Kander, T., Hästbacka, J., Andreasen, J. B., Péju, E., Nielsen, L. B., Hvas, C. L. & 101 others, Dufranc, E., Canet, E., Lundqvist, L., Wright, C. J., Schmidt, J., Uhel, F., Ait-Oufella, H., Krag, M., Cos Badia, E., Díaz-Lagares, C., Menat, S., Voiriot, G., Clausen, N. E., Lorentzen, K., Kvåle, R., Hildebrandt, T., Holten, A. R., Strand, K., Tzalavras, A., Bestle, Morten Heiberg, Klepstad, P., Fernandez, S., Vimpere, D., Costa, C., Graça, C., Lueck, C., Juhl, C. S., Costa, C., Bådstøløkken, P. M., Miranda, T., Lêdo, L. S. A., Sousa Torres, J. C., Granholm, A., Møller, Morten Hylander, Russell, Lene, Khalil, A., Yehia, A., Salem, H., Farahat, H., Sudevan, M., Biggart, M., Fatima, N., Elkhonezy, M., Bunzel, A. M., Siegumfeldt, R. M., Vestergaard, S. R., Pelle, J., Lê, M. P., Vigneron, C., Bertrix, M., Cirera, P., Laghlam, D., Bredin, S., Marin, N., Toppenberg, M., Benelli, B., Seguin, A., Garret, C., Guillotin, F., Blonz, G., Lascarrou, J. B., Lemarie, J., Desmedt, L., Agbakou, M., Carpentier, M., Martin, M., Benkalfate, N., Zambon, O., Decamps, P., Wilquin, P. L., Benguerfi, S., Gardner, J., Remor, N., Carr, S., Yang, G., Gernez, C., Thiry, I., Missri, L., Denneborg, M. K. G., Brown, K., Casares, V., Sivula, M., Lappi, E., Pettilä, L., Heinonen, J., Saario, M., Mecheri, M. K., Elabbadi, A., Desnos, C., Lafarge, A., Mghirbi, O., Sjøbø, B., Christoffersen, C., Bestle, F. H., Lemos, C., Gonçalves, C. V., Jacinto, N. M. B., Anselmo, M. P., Hoeper, M. M., Hoff, M. & Simões Freire, P. M., 2023, In: Intensive Care Medicine. 49, 11, p. 1327-1338 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2022
  28. Published

    Agents intervening against delirium in the intensive care unit trial — Protocol for a secondary Bayesian analysis

    Andersen-Ranberg, N., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M. P. G., Citerio, G., Oxenbøll-Collet, M., Weber, S., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. B. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 7, p. 898-903

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Clinical assessment as a part of an early warning score-a Danish cluster-randomised, multicentre study of an individual early warning score

    Nielsen, P. B., Langkjaer, C. S., Schultz, M., Kodal, A. M., Pedersen, N. E., Petersen, J. A., Lange, Theis, Arvig, Michael Dan, Meyhoff, Christian Sylvest, Bestle, Morten Heiberg, Hølge-Hazelton, B., Bunkenborg, G., Lippert, A., Andersen, Ove, Rasmussen, L. S. & Iversen, Kasper, 2022, In: Lancet digital health. 4, 7, p. E497-E506 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial

    Granholm, A., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Kjaer, M-B. N., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Moller, M. H., Benfield, T., Venkatesh, B., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, V. & 26 others, Kristiansen, Klaus Tjelle, Ulrik, Charlotte Suppli, Jorgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brochner, A. C., Strom, T., Moller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Wamberg, C. A., Gluud, C., Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, p. 45–55 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Early Biomarker-Guided Prediction of Bloodstream Infection in Critically Ill Patients: C-Reactive Protein, Procalcitonin, and Leukocytes

    Hertz, Frederik Boëtius, Ahlström, M. G., Bestle, Morten Heiberg, Hein, L., Mohr, T., Lundgren, Jens, Galle, T., Andersen, M. H., Murray, D., Lindhardt, A., Itenov, Theis Skovsgaard & Jensen , Jens-Ulrik Stæhr , 2022, In: Open Forum Infectious Diseases. 9, 10, ofac467.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Endotheliopathy is associated with slower liberation from mechanical ventilation: a cohort study

    Schønemann-Lund, M., Itenov, T. S., Larsson, J. E., Lindegaard, Birgitte, Jo­hans­son, Pär In­ge­mar & Bestle, Morten Heiberg, 2022, In: Critical Care. 26, 1, 33.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Endotracheal lactate reflects lower respiratory tract infections and inflammation in intubated patients

    Kolpen, M., Dalby Sørensen, C., Faurholt-Jepsen, D., Hertz, Frederik Boëtius, Jensen, Peter Østrup & Bestle, Morten Heiberg, 2022, In: APMIS. 130, 8, p. 507-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Goal directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A trial protocol for a randomised, blinded trial (GODIF trial)

    Wichmann, S., Itenov, T. S., Berthelsen, R. E., Lange, T., Perner, A., Gluud, C., Lawson-Smith, P., Nebrich, L., Wiis, J., Brøchner, A. C., Hildebrandt, T., Behzadi, M. T., Strand, K., Andersen, F. H., Strøm, T., Järvisalo, M., Damgaard, K. A. J., Vang, M. L., Wahlin, R. R., Sigurdsson, M. I. & 4 others, Thormar, K. M., Ostermann, M., Keus, F. & Bestle, Morten Heiberg, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 9, p. 1138-1145 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Haloperidol for the Treatment of Delirium in ICU Patients

    Andersen-Ranberg, N. C., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Haestbacka, J., Morgan, M., Citerio, G., Caballero, J., Lange, T., Kjaer, M-B. N., Ebdrup, B. H., Engstrom, J., Olsen, M. H., Oxenboll Collet, M., Mortensen, C. B., Weber, S-O., Andreasen, A. S., Bestle, M. H., Uslu, B. & 28 others, Scharling Pedersen, H., Gramstrup Nielsen, L., Toft Boesen, H. C., Jensen, J. V., Nebrich, L., La Cour, K., Laigaard, J., Haurum, C., Olesen, M. W., Overgaard-Steensen, C., Westergaard, B., Brand, B. A., Kingo Vesterlund, G., Thornberg Kyhnauv, P., Mikkelsen, V. S., Hyttel-Sorensen, S., de Haas, I., Aagaard, S. R., Nielsen, L. O., Eriksen, A. S., Rasmussen, B. S., Brix, H., Hildebrandt, T., Schonemann-Lund, M., Fjeldsoe-Nielsen, H., Kuivalainen, A., Mathiesen, Ole & AID ICU Trial Grp, 2022, In: New England Journal of Medicine. 387, 20, p. 2425-2435 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia

    Granholm, A., Kjær, M-B. N., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Møller, M. H., Benfield, T., Venkatesh, B., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, V. & 29 others, Kristiansen, Klaus Tjelle, Ulrik, Charlotte Suppli, Jørgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brochner, A. C., Strøm, T., Møller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Wamberg, C. A., Bose, N., Shah, M. S., Darfelt, I. S., Gluud, C., Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, 5, p. 580–589 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Loop diuretics in adult intensive care patients with fluid overload: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

    Wichmann, S., Barbateskovic, M., Liang, N., Itenov, Theis Skovsgaard, Berthelsen, R. E., Lindschou, J., Perner, Anders, Gluud, C. & Bestle, Morten Heiberg, 2022, In: Annals of Intensive Care. 12, 1, 16 p., 52.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Nordic survey on assessment and treatment of fluid overload in intensive care

    Zeuthen, E., Wichmann, S., Schønemann-Lund, M., Järvisalo, M. J., Rubenson-Wahlin, R., Sigurðsson, M. I., Holen, E. & Bestle, Morten Heiberg, 2022, In: Frontiers in Medicine. 9, 1067162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Oxygenation targets in ICU patients with COVID-19: a post-hoc sub-group analysis of the HOT-ICU trial

    Rasmussen, B. S., Klitgaard, T. L., Perner, A., Brand, B. A., Hildebrandt, T., Siegemund, M., Hollinger, A., Aagaard, S. R., Bestle, M. H., Marcussen, K. V., Brøchner, A. C., Sølling, C. G., Poulsen, L. M., Laake, J. H., Aslam, T. N., Bäcklund, M., Okkonen, M., Morgan, M., Sharman, M., Lange, T. & 2 others, Wetterslev, J. & Schjørring, O. L., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 76-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Prostacyclin in Mechanically Ventilated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized, Clinical Trial

    Johansson, P. I., Søe-Jensen, P., Bestle, Morten Heiberg, Clausen, N. E., Kristiansen, Klaus Tjelle, Lange, Theis, Stensballe, J. & Perner, Anders, 2022, In: American Journal of Respiratory and Critical Care Medicine. 205, 3, p. 324-329 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Rapid response teams—how and who? A protocol for a randomised clinical trial evaluating the composition of the efferent limb of the rapid response system

    Føns-Sønderskov, M. B., Subbe, C., Kodal, A. M., Bunkenborg, G. & Bestle, Morten Heiberg, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 3, p. 401-407

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Restriction of Intravenous Fluid in ICU Patients with Septic Shock

    Meyhoff, T. S., Hjortrup, P. B., Wetterslev, J., Sivapalan, P., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M., Pettila, V., Møller, M. H., Kjaer, M-B. N., Lange, T., Overgaard-Steensen, C., Brand, B. A., Winther-Olesen, M., White, J. O., Quist, L. & 48 others, Westergaard, B., Jonsson, A. B., Hjortso, C. J. S., Meier, N., Jensen, T. S., Engstrom, J., Nebrich, L., Andersen-Ranberg, N. C., Jensen, J. V., Joseph, N. A., Poulsen, L. M., Herlov, L. S., Solling, C. G., Pedersen, S. K., Knudsen, K. K., Straarup, T. S., Vang, M. L., Bundgaard, H., Rasmussen, B. S., Aagaard, S. R., Hildebrandt, T., Russell, Lene, Bestle, Morten Heiberg, Schonemann-Lund, M., Brochner, A. C., Elvander, C. F., Hoffmann, S. K. L., Rasmussen, M. L., Martin, Y. K., Friberg, F. F., Seter, H., Aslam, T. N., Adnoy, S., Seidel, P., Strand, K., Johnstad, B., Joelsson-Alm, E., Christensen, J., Ahlstedt, C., Pfortmueller, C. A., Siegemund, M., Greco, M., Radej, J., Kriz, M., Gould, D. W., Rowan, K. M., Mouncey, P. R. & Perner, Anders, 2022, In: New England Journal of Medicine. 386, p. 2459-2470 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Risk factors for fatigue and impaired function eight months after hospital admission with COVID-19

    Schouborg, L. B., Mølsted, Stig, Lendorf, M. E., Hegelund, M. H., Ryrsø, C. K., Sommer, D. H., Kolte, L., Nolsöe, R. L., Pedersen, T. I., Harboe, Z. B., Browatzki, A., Brandi, L., Krog, S. M., Bestle, Morten Heiberg, Jørgensen, Inger Merete, Jensen, T. Ø., Fischer, Thea Kølsen, Pedersen-Bjergaard, Ulrik & Lindegaard, Birgitte, 2022, In: Danish Medical Journal. 69, 4, 9 p., A08210633.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The effect of prostacyclin infusion on markers of endothelial activation and damage in mechanically ventilated patients with SARS-CoV-2 infection

    Vigstedt, M., Søe-Jensen, P., Bestle, Morten Heiberg, Clausen, N. E., Kristiansen, Klaus Tjelle, Lange, Theis, Stensballe, J., Perner, Anders & Jo­hans­son, Pär In­ge­mar , 2022, In: Journal of Critical Care. 69, 154010.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2021
  46. Published

    Cardiac arrhythmias in critically ill patients with coronavirus disease 2019: A retrospective population-based cohort study

    Wetterslev, M., Jacobsen, P. K., Hassager, Christian, Jøns, C., Risum, N., Pehrson, S., Bastiansen, A., Andreasen, Anne Sofie, Tjelle Kristiansen, K., Bestle, Morten Heiberg, Mohr, T., Møller-Sørensen, H. & Perner, Anders, Jul 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 770-777 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Første danske tilfælde af tick-borne encefalitis trods forudgående vaccination

    Andersen, N. S., Jepsen, M. P. G., Witt, A. M., Franck, K. T. & Bestle, Morten Heiberg, 22 Feb 2021, In: Ugeskrift for Laeger. 183, 8, 4 p., V11200812.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

    on behalf of the DecubICUs Study Team, O. B. O. T. D. S. T. & the European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators, T. E. S. O. I. C. M. (. T. G. C., Feb 2021, In: Intensive Care Medicine. 47, 2, p. 160-169 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    ABO blood types and sepsis mortality

    Itenov, T. S., Sessler, D. I., Khanna, A. K., Ostrowski, Sisse Rye, Johansson, P. I., Erikstrup, C., Pedersen, O. B., Rygård, S. L., Holst, L. B., Bestle, Morten Heiberg, Hein, L., Lindhardt, A., Tousi, H., Andersen, M. H., Mohr, T., Lundgren, Jens & Jensen , Jens-Ulrik Stæhr , 2021, In: Annals of Intensive Care. 11, 1, 61.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Bioimpedance as a measure of fluid status in critically ill patients: A systematic review

    Madsen, J. M., Wichmann, S., Bestle, Morten Heiberg & Itenov, T. S., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1155-1167

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia The COVID STEROID 2 Randomized Trial

    Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Saseedharan, S., Benfield, T., Wahlin, R. R., Rasmussen, B. S., Andreasen, A. S., Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brochner, A. C., Bestle, M. H., Helleberg, M., Michelsen, J., Padmanaban, A., Bose, N., Møller, A. & 59 others, Borawake, K., Kristiansen, K. T., Shukla, U., Chew, M. S., Dixit, S., Ulrik, Charlotte Suppli, Amin, P. R., Chawla, R., Wamberg, C. A., Shah, M. S., Darfelt, I. S., Jorgensen, V. L., Smitt, M., Granholm, A., Kjær, M. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, A., Cronhjort, M., Jakob, S. M., Gluud, C., Lange, Theis, Kadam, V., Marcussen, Klaus Vennick, Hollenberg, J., Hedman, A., Nielsen, H., Schjorring, O. L., Jensen, M. Q., Leistner, J. W., Jonassen, T. B., Kristensen, C. M., Clapp, E. C., Hjortso, C. J. S., Jensen, T. S., Halstad, L. S., Bak, E. R. B., Zaabalawi, R., Metcalf-Clausen, M., Abdi, S., Hatley, E. V., Aksnes, T. S., Gleipner-Andersen, E., Alarcon, A. F., Yamin, G., Heymowski, A., Berggren, A., La Cour, K., Weihe, S., Pind, A. H., Engstrom, J., Jha, V., Venkatesh, B. & Perner, Anders, 2021, In: J A M A: The Journal of the American Medical Association. 326, 18, p. 1807-1817 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Handling oxygenation targets in ICU patients with COVID-19—Protocol and statistical analysis plan in the HOT-COVID trial

    Mølgaard Nielsen, F., Lass Klitgaard, T., Crescioli, E., Rosborg Aagaard, S., Andreasen, Anne Sofie, Musaeus Poulsen, L., Siegemund, M., Craveiro Brøchner, A., Bestle, Morten Heiberg, Andi Iversen, S., Brand, B. A., Laake, J. H., Grøfte, T., Hildebrandt, T., Lange, Theis, Perner, Anders, Lilleholt Schjørring, O. & Steen Rasmussen, B., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 10, p. 1497-1504 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Higher vs Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: Protocol for a secondary Bayesian analysis

    Granholm, A., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Kjær, M. B. N., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Møller, M. H., Benfield, T., Venkatesh, B., Hammond, N., Micallef, S., Bassi, A., John, O., Jha, V. & 25 others, Kristiansen, K. T., Ulrik, Charlotte Suppli, Jørgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brøchner, A. C., Strøm, T., Møller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Gluud, C., Lange, Theis & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 5, p. 702-710 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Higher vs lower doses of dexamethasone in patients with COVID-19 and severe hypoxia (COVID STEROID 2) trial: Protocol and statistical analysis plan

    Warrer Munch, M., Granholm, A., Nainan Myatra, S., Kumar Tirupakuzhi Vijayaraghavan, B., Cronhjort, M., Rubenson Wahlin, R., Jakob, S. M., Cioccari, L., Nørregaard Kjær, M. B., Kingo Vesterlund, G., Sylvest Meyhoff, T., Helleberg, M., Hylander Møller, M., Benfield, T., Venkatesh, B., Hammond, N., Micallef, S., Bassi, A., John, O., Jha, V. & 25 others, Tjelle Kristiansen, K., Ulrik, Charlotte Suppli, Lind Jørgensen, V., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Musaeus Poulsen, L., Steen Rasmussen, B., Craveiro Brøchner, A., Strøm, T., Møller, A., Saif Khan, M., Padmanaban, A., Vasishtha Divatia, J., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Gluud, C., Lange, Theis & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 834-845 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 32365843