Morten Bækgaard Thomsen

Morten Bækgaard Thomsen

Associate Professor


  1. 2003
  2. Published

    Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes

    Stengl, M., Volders, P. G. A., Thomsen, Morten Bækgaard, Spätjens, R. L. H. M. G., Sipido, K. R. & Vos, M. A., 15 Sep 2003, In: Journal of Physiology. 551, Pt 3, p. 777-86 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Electrophysiological safety of sertindole in dogs with normal and remodeled hearts

    Thomsen, Morten Bækgaard, Volders, P. G. A., Stengl, M., Spätjens, R. L. H. M. G., Beekman, J. D. M., Bischoff, U., Kall, M. A., Frederiksen, K., Matz, J. & Vos, M. A., Nov 2003, In: Journal of Pharmacology and Experimental Therapeutics. 307, 2, p. 776-84 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. 2004
  5. Published

    Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

    Thomsen, Morten Bækgaard, Verduyn, S. C., Stengl, M., Beekman, J. D. M., de Pater, G., van Opstal, J., Volders, P. G. A. & Vos, M. A., 19 Oct 2004, In: Circulation. 110, 16, p. 2453-9 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. 2005
  7. Published
  8. Published

    Sudden cardiac death in dogs with remodeled hearts is associated with larger beat-to-beat variability of repolarization

    Thomsen, Morten Bækgaard, Truin, M., van Opstal, J. M., Beekman, J. D. M., Volders, P. G. A., Stengl, M. & Vos, M. A., May 2005, In: Basic Research in Cardiology. 100, 3, p. 279-87 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Decreasing the infusion rate reduces the proarrhythmic risk of NS-7: confirming the relevance of short-term variability of repolarisation in predicting drug-induced torsades de pointes

    Detre, E., Thomsen, Morten Bækgaard, Beekman, J. D., Petersen, K. & Vos, M. A., Jun 2005, In: British Journal of Pharmacology. 145, 3, p. 397-404 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. 2006
  11. Published

    Beat-to-Beat variability of repolarization determines proarrhythmic outcome in dogs susceptible to drug-induced torsades de pointes

    Thomsen, Morten Bækgaard, Volders, P. G. A., Beekman, J. D. M., Matz, J. & Vos, M. A., 19 Sep 2006, In: Journal of the American College of Cardiology. 48, 6, p. 1268-76 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Assessing the proarrhythmic potential of drugs: current status of models and surrogate parameters of torsades de pointes arrhythmias

    Thomsen, Morten Bækgaard, Matz, J., Volders, P. G. A. & Vos, M. A., Oct 2006, In: Pharmacology & Therapeutics. 112, 1, p. 150-70 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    No proarrhythmic properties of the antibiotics Moxifloxacin or Azithromycin in anaesthetized dogs with chronic-AV block

    Thomsen, Morten Bækgaard, Beekman, J. D. M., Attevelt, N. J. M., Takahara, A., Sugiyama, A., Chiba, K. & Vos, M. A., Dec 2006, In: British Journal of Pharmacology. 149, 8, p. 1039-48 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2007
  15. Published

    Proarrhythmic electrical remodelling is associated with increased beat-to-beat variability of repolarisation

    Thomsen, Morten Bækgaard, Oros, A., Schoenmakers, M., van Opstal, J. M., Maas, J. N., Beekman, J. D. M. & Vos, M. A., 1 Feb 2007, In: Cardiovascular Research. 73, 3, p. 521-30 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Double pharmacological challenge on repolarization opens new avenues for drug safety research

    Thomsen, Morten Bækgaard, Aug 2007, In: British Journal of Pharmacology. 151, 7, p. 909-11 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    High-septal pacing reduces ventricular electrical remodeling and proarrhythmia in chronic atrioventricular block dogs

    Winckels, S. K. G., Thomsen, Morten Bækgaard, Oosterhoff, P., Oros, A., Beekman, J. D. M., Attevelt, N. J. M., Kretzers, L. & Vos, M. A., 28 Aug 2007, In: Journal of the American College of Cardiology. 50, 9, p. 906-13 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. 2008
  19. Published

    Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration

    Thomsen, Morten Bækgaard, Sosunov, E. A., Anyukhovsky, E. P., Ozgen, N., Boyden, P. A. & Rosen, M. R., 2008, In: Heart Rhythm. 6, 3, p. 370-7 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study

    Hinterseer, M., Thomsen, Morten Bækgaard, Beckmann, B., Pfeufer, A., Schimpf, R., Wichmann, H., Steinbeck, G., Vos, M. A. & Kaab, S., Jan 2008, In: European Heart Journal. 29, 2, p. 185-90 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. 2009
  22. Published

    Accessory subunit KChIP2 modulates the cardiac L-type calcium current

    Thomsen, Morten Bækgaard, Wang, C., Ozgen, N., Wang, H., Rosen, M. R. & Pitt, G. S., 2009, In: Circulation Research. 104, 12, p. 1382-9 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Relation of increased short-term variability of QT interval to congenital long-QT syndrome

    Hinterseer, M., Beckmann, B., Thomsen, Morten Bækgaard, Pfeufer, A., Dalla Pozza, R., Loeff, M., Netz, H., Steinbeck, G., Vos, M. A. & Kääb, S., 2009, In: American Journal of Cardiology. 103, 9, p. 1244-8 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Transcriptional and electrophysiological consequences of KChIP2-mediated regulation of CaV1.2

    Thomsen, Morten Bækgaard, Foster, E., Nguyen, K. H. & Sosunov, E. A., 2009, In: Channels (Austin). 3, 5, p. 308-10 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. 2010
  26. Published

    Usefulness of short-term variability of QT intervals as a predictor for electrical remodeling and proarrhythmia in patients with nonischemic heart failure

    Hinterseer, M., Beckmann, B., Thomsen, Morten Bækgaard, Pfeufer, A., Ulbrich, M., Sinner, M. F., Perz, S., Wichmann, H., Lengyel, C., Schimpf, R., Maier, S. K. G., Varró, A., Vos, M. A., Steinbeck, G. & Kääb, S., 15 Jul 2010, In: Journal of the American College of Cardiology. 106, 2, p. 216-20 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Repolarization variability and early afterdepolarizations in long QT syndrome type 2: is labile calcium the common denominator?

    Antoons, G. & Thomsen, Morten Bækgaard, 1 Nov 2010, In: Heart Rhythm. 7, 11, p. 1695-6 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    High-Rate Pacing Reduces Variability of Repolarization and Prevents Repolarization-Dependent Arrhythmias in Dogs With Chronic AV Block

    Oosterhoff, P., Thomsen, Morten Bækgaard, Maas, J. N., Atteveld, N. J. M., Beekman, J. D. M., VAN Rijen, H. V. M., VAN DER Heyden, M. A. G. & Vos, M. A., 1 Dec 2010, In: Journal of Cardiovascular Electrophysiology. 21, 12, p. 1384-91 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. 2011
  30. Published

    Strengthening intercellular communication to prevent atrial fibrillation

    Thomsen, Morten Bækgaard, 1 Nov 2011, In: Cardiovascular Research. 92, 2, p. 187-8 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. 2012
  32. Published

    Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

    Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes

    Nalos, L., Varkevisser, R., Jonsson, M., Houtman, M., Beekman, J., van der Nagel, R., Thomsen, Morten Bækgaard, Duker, G., Sartipy, P., de Boer, T., Peschar, M., Rook, M., van Veen, T., van der Heyden, M. & Vos, M., 2012, In: British Journal of Pharmacology. 165, 2, p. 467-478

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure

    Grubb, Søren, Callø, Kirstine & Thomsen, Morten Bækgaard, 2012, In: Frontiers in Physiology. 3, p. 118

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Triangulation of the monophasic action potential causes flattening of the electrocardiographic T-wave

    Bhuiyan, T. A., Graff, C., Thomsen, Morten Bækgaard & Struijk, J. J., 1 Jan 2012, Computing in Cardiology. Vol. 39. p. 757-760 4 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  36. Published

    Special Interest Group on Cardiac Physiology established within the Scandinavian Physiological Society

    Thomsen, Morten Bækgaard & Louch, W. E., Apr 2012, In: Acta Physiologica (Print). 204, 4, p. 464

    Research output: Contribution to journalJournal article

  37. Published

    Torsades de Pointes in the Guinea-pig heart: editorial to: "dofetilide promotes repolarization abnormalities in perfused Guinea-pig heart" by O.E. Osadchii

    Soltysinska, E. & Thomsen, Morten Bækgaard, Dec 2012, In: Cardiovascular Drugs and Therapy. 26, 6, p. 437-9 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. 2013
  39. Published

    Flattening of the electrocardiographic T-wave is a sign of proarrhythmic risk and a reflection of action potential triangulation

    Bhuiyan, T. A., Graff, C., Kanters, Jørgen K., Thomsen, Morten Bækgaard & Struijk, J. J., 1 Jan 2013, Computing in Cardiology. Vol. 40. p. 353-356 4 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  40. Published

    In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

    Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Kv7.1 isoform gradients in the heart: new potential approach to alter repolarization reserve

    Thomsen, Morten Bækgaard, Aug 2013, In: Heart rhythm : the official journal of the Heart Rhythm Society. 10, 8, p. 1229-30 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Physiology and analysis of the electrocardiographic T wave in mice

    Speerschneider, T. & Thomsen, Morten Bækgaard, Dec 2013, In: Acta Physiologica. 209, 4, p. 262-71 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Development of heart failure is independent of K+ channel-interacting protein 2 expression

    Speerschneider, T., Grubb, Søren, Metoska, A., Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 1 Dec 2013, In: Journal of Physiology. 591, 23, p. 5923-37 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. 2014
  45. Published

    KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

    Soltysinska, E., Bentzen, B. H., Barthmes, M., Hattel, H., Thrush, A. B., Harper, M-E., Qvortrup, K., Larsen, F. J., Schiffer, T. A., Losa-Reyna, J., Straubinger, J., Kniess, A., Thomsen, M. B., Brüggemann, A., Fenske, S., Biel, M., Ruth, P., Wahl-Schott, C., Boushel, R. C., Olesen, S-P. & 1 others, Lukowski, R., 2014, In: PLOS ONE. 9, 7, p. 1-12 12 p., e103402.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Loss of K+ currents in heart failure is accentuated in KChIP2 deficient mice

    Grubb, Søren, Speerschneider, T., Occhipinti, D., Fiset, C., Olesen, Søren-Peter, Thomsen, Morten Bækgaard & Callø, Kirstine, 2014, In: Journal of Cardiovascular Electrophysiology. 25, 8, p. 896-904 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Sinoatrial node dysfunction induces cardiac arrhythmias in diabetic mice

    Soltysinska, E., Speerschneider, T., Winther, S. V. & Thomsen, Morten Bækgaard, 12 Aug 2014, In: Cardiovascular Diabetology. 13, 1, p. 1-11 11 p., 122.

    Research output: Contribution to journalJournal articlepeer-review

  48. 2015
  49. Published

    Assessment of anti-arrhythmic activity of antipsychotic drugs in an animal model: Influence of non-cardiac α1-adrenergic receptors

    Mow, T., Frederiksen, K. & Thomsen, Morten Bækgaard, 5 Feb 2015, In: European Journal of Pharmacology. 748, p. 10-17 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

    Grubb, Søren, Aistrup, G. L., Koivumäki, J. T., Speerschneider, T., Gottlieb, Lisa Amalie, Mutsaers, N. A. M., Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H481-H489 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. 2016
  52. Published

    Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling

    Winther, S. V., Tuomainen, T., Borup, R., Tavi, P., Antoons, G. & Thomsen, Morten Bækgaard, 2016, In: Scientific Reports. 6, 12 p., 28760.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Human atrial fibroblasts and their contribution to supraventricular arrhythmia

    Thomsen, Morten Bækgaard & Callø, Kirstine, Feb 2016, In: Physiological Reports. 4, 3, 3 p., e12711.

    Research output: Contribution to journalEditorialpeer-review

  54. Published

    Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice

    Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. 2017
  56. Published

    Circadian rhythm in QT interval is preserved in mice deficient of potassium channel interacting protein 2

    Gottlieb, Lisa Amalie, Lubberding, Anniek Frederike, Larsen, A. P. & Thomsen, Morten Bækgaard, Jan 2017, In: Chronobiology International. 34, 1, p. 45-56 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

    Speerschneider, T., Grubb, Søren, Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 9 Feb 2017, In: Acta Physiologica. 219, 3, p. 662-670 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  58. 2018
  59. Published

    Potassium channels in the heart

    Thomsen, Morten Bækgaard, 2018, Channelopathies in Heart Disease. Thomas, D. & Remme, C. A. (eds.). Springer, p. 47-75 (Cardiac and Vascular Biology, Vol. 6).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  60. Published

    Ultrasonographic and histological evaluation of the effects of long-term carotid catheterization on cardiac function in NMRI mice

    Teilmann, A. C., Thomsen, Morten Bækgaard, Ihms, E. A., Pate, N., Hau, Jann & Abelson, Klas, Feb 2018, In: Laboratory Animals. 52, 1, p. 17-28

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Nav1.5 gain-of-function mutation (G213D)

    Callø, Kirstine, Broendberg, A. K., Christensen, A. H., Pedersen, L. N., Olesen, Morten Steen Salling, de Los Angeles Tejada, M., Friis, S., Thomsen, Morten Bækgaard, Bundgård, Henning & Jensen, H. K., 15 Apr 2018, In: International Journal of Cardiology. 257, p. 160-167 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    Uremia increases QRS duration after β-adrenergic stimulation in mice

    Thomsen, Morten Bækgaard, Nielsen, Morten Schak, Aarup, A., Bisgaard, Line & Pedersen, T. X., 1 Jul 2018, In: Physiological Reports. 6, 13, 13 p., e13720.

    Research output: Contribution to journalJournal articlepeer-review

  63. 2019
  64. Published

    Low-Dose Adrenaline Reduces Blood Pressure Acutely in Anesthetized Pigs Through a beta(2)-Adrenergic Pathway

    Lubberding, Anniek Frederike & Thomsen, Morten Bækgaard, 2019, In: Journal of Cardiovascular Pharmacology. 74, 1, p. 38-43

    Research output: Contribution to journalJournal articlepeer-review

  65. 2020
  66. Published

    Aberrant sinus node firing during beta-adrenergic stimulation leads to cardiac arrhythmias in diabetic mice

    Lubberding, Anniek Frederike, Pereira, L., Xue, J., Gottlieb, Lisa Amalie, Matchkov, V. V., Gomez, A. M. & Thomsen, Morten Bækgaard, 2020, In: Acta Physiologica. 229, 1, 12 p., e13444.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    An American Physiological Society cross-journal Call for Papers on "Deconstructing Organs Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models"

    Adams, J. C., Bell, P. D., Bodine, S. C., Brooks, H. L., Bunnett, N., Joe, B., Keehan, K. H., Kleyman, T. R., Marette, A., Morty, R. E., Ramirez, J., Thomsen, Morten Bækgaard, Yates, B. J. & Zucker, I. H., 2020, In: American Journal of Physiology: Lung Cellular and Molecular Physiology. 319, 2, p. L266-L272 7 p.

    Research output: Contribution to journalEditorialpeer-review

  68. 2021
  69. Published

    Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE−/− mice

    Christophersen, D. V., Møller, Peter, Thomsen, Morten Bækgaard, Lykkesfeldt, Jens, Loft, Steffen, Wallin, H., Vogel, U. & Jacobsen, N. R., 2021, In: FASEB Journal. 35, 3, 14 p., e21307.

    Research output: Contribution to journalJournal articlepeer-review

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