Michal Tomasz Marzec

Michal Tomasz Marzec

Guest researcher


  1. 2011
  2. Published

    Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA

    Marzec, Michal Tomasz, Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Woetmann, Anders , Cheng, M., Ødum, Niels & Wasik, M. A., 2011, In: Oncogene. 30, 11, p. 1372-1378 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2010
  4. Plasma gelsolin modulates cellular response to sphingosine 1-phosphate

    Bucki, R., Kulakowska, A., Byfield, F. J., Zendzian-Piotrowska, M., Baranowski, M., Marzec, Michal Tomasz, Winer, J. P., Ciccarelli, N. J., Gorski, J., Drozdowski, W., Bittman, R. & Janmey, P. A., 2010, In: American Journal of Physiology: Cell Physiology. 299, 6, p. C1516-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2009
  6. Activation of mTORC1 signaling pathway in AIDS-related lymphomas.

    El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Robertson, E. & Wasik, M. A., 2009, In: American Journal of Pathology. 175, 2, p. 817-824 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches

    Wasik, M. A., Zhang, Q., Marzec, Michal Tomasz, Kasprzycka, M., Wang, H. Y. & Liu, X., 2009, In: Seminars in Oncology. 36, 2 Suppl 1, p. S27-35

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2008
  9. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

    Marzec, Michal Tomasz, Zhang, Q., Goradia, A., Raghunath, P. N., Liu, X., Paessler, M., Wang, H. Y., Wysocka, M., Cheng, M., Ruggeri, B. A. & Wasik, M. A., 30 Dec 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 52, p. 20852-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4(+) T lymphocytes

    Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 15 Aug 2008, In: Journal of Immunology. 181, 4, p. 2506-2512

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Expression of FOXP3(+) regulatory T-cell phenotype in neoplastic and reactive cells in early mycosis fungoides

    Witkiewicz, A. K., Potoczek, M., Kasprzycka, M., Marzec, Michal Tomasz & Wasik, M., Jan 2008, In: Modern Pathology. 21, p. 103A-103A

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

    Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

    Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    γc-Signaling Cytokines Induce a Regulatory T Cell Phenotype in Malignant CD4+ T Lymphocytes.

    Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, Michal Tomasz, Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Ødum, Niels & Wasik, M. A., 2008, In: Journal of Immunology. 181, 4, p. 2506-2512 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2007
  16. Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.

    El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Wlodarski, P., Tsai, D., Hsi, E. & Wasik, M. A., 2007, In: Laboratory Investigation. 87, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

    Marzec, Michal Tomasz, Kasprzycka, M., Liu, X., Raghunath, P. N., Wlodarski, P. & Wasik, M. A., 2007, In: Oncogene. 26, 6, p. 813-821 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

    Marzec, Michal Tomasz, Kasprzycka, M., Liu, X., El-Salem, M., Halasa, K., Raghunath, P. N., Bucki, R., Wlodarski, P. & Wasik, M. A., 2007, In: Oncogene. 26, 38, p. 5606-5614 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. PU.1 activates transcription of SHP-1 gene in hematopoietic cells.

    Wlodarski, P., Zhang, Q., Liu, X., Kasprzycka, M., Marzec, Michal Tomasz & Wasik, M. A., 2007, In: Journal of Biological Chemistry. 282, 9, p. 6316-6323 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2006
  21. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity

    Marzec, Michal Tomasz, Kasprzycka, M., Lai, R., Gladden, A. B., Wlodarski, P., Tomczak, E., Nowell, P., DePrimo, S. E., Sadis, S., Eck, S., Schuster, S. J., Diehl, J. A. & Wasik, M. A., 1 Sep 2006, In: Blood. 108, 5, p. 1744-1750

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3

    Kasprzycka, M., Marzec, Michal Tomasz, Liu, X., Zhang, Q. & Wasik, M. A., 27 Jun 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 26, p. 9964-9969

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

    Kasprzycka, M., Majewski, M., Wang, Z., Ptasznik, A., Wysocka, M., Zhang, Q., Marzec, Michal Tomasz, Gimotty, P., Crompton, M. R. & Wasik, M. A., 2006, In: American Journal of Pathology. 168, 5, p. 1631-1641 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Jak3 contributes to the activation of ALK and Stat3 in ALK + anaplastic large cell lymphoma. Response.

    Wasik, M. A. & Marzec, Michal Tomasz, 2006, In: Laboratory Investigation. 86, 4, p. 420-421 2 p.

    Research output: Contribution to journalLetterResearch

  25. Published

    Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing

    Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Peroxisome Proliferator-Activated Receptor γ Promotes Lymphocyte Survival through Its Actions on Cellular Metabolic Activities.

    Jo, S., Yang, C., Miao, Q., Marzec, Michal Tomasz, Wasik, M. A., Lu, P. & Wang, Y. L., 2006, In: Journal of Immunology. 177, 6, p. 3737-3745 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2005
  28. Activation of Mammalian Target of Rapamycin in Transformed B Lymphocytes Is Nutrient Dependent but Independent of Akt, Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase, Insulin Growth Factor-I, and Serum.

    Wlodarski, P., Kasprzycka, M., Liu, X., Marzec, Michal Tomasz, Robertson, E. S., Slupianek, A. & Wasik, M. A., 2005, In: Cancer Research. 65, 17, p. 7800-7808 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

    Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

    Zhang, Q., Wang, H. Y., Marzec, Michal Tomasz, Raghunath, P. N., Nagasawa, T. & Wasik, M. A., 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 19, p. 6948-6953 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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