Michal Tomasz Marzec

Michal Tomasz Marzec

Guest researcher


  1. Published

    In silico approach to predict pancreatic β-cells classically secreted proteins

    Pinheiro-Machado, E., Sandberg, T. O. M., Pihl, Celina, Hägglund, Per Mårten & Marzec, Michal Tomasz, 1 Jan 2020, In: Bioscience Reports. 40, 2, 13 p., BSR20193708.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

    Marzec, Michal Tomasz, Hawkes, C. P., Eletto, D., Boyle, S., Rosenfeld, R. G., Hwa, V., Wit, J. M., van Duyvenvoorde, H. A., Oostdijk, W., Losekoot, M., Pedersen, Oluf Borbye, Yeap, B. B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A. & Argon, Y., May 2016, In: Endocrinology. 157, 5, p. 1914-1928 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Activation of Mammalian Target of Rapamycin in Transformed B Lymphocytes Is Nutrient Dependent but Independent of Akt, Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase, Insulin Growth Factor-I, and Serum.

    Wlodarski, P., Kasprzycka, M., Liu, X., Marzec, Michal Tomasz, Robertson, E. S., Slupianek, A. & Wasik, M. A., 2005, In: Cancer Research. 65, 17, p. 7800-7808 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Activation of mTORC1 signaling pathway in AIDS-related lymphomas.

    El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Robertson, E. & Wasik, M. A., 2009, In: American Journal of Pathology. 175, 2, p. 817-824 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches

    Wasik, M. A., Zhang, Q., Marzec, Michal Tomasz, Kasprzycka, M., Wang, H. Y. & Liu, X., 2009, In: Seminars in Oncology. 36, 2 Suppl 1, p. S27-35

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.

    El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Wlodarski, P., Tsai, D., Hsi, E. & Wasik, M. A., 2007, In: Laboratory Investigation. 87, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma.

    Lee, S., Marzec, Michal Tomasz, Liu, X., Wehrli, S., Kantekure, K., Ragunath, P. N., Nelson, D. S., Delikatny, E. J., Glickson, J. D. & Wasik, M. A., 2013, In: NMR in Biomedicine. 26, 1, p. 106-114 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells

    Khilji, Muhammad Saad, Faridi, P., Pinheiro-Machado, E., Hoefner, C., Dahlby, T., Aranha, R., Buus, Søren, Nielsen, M., Klusek, J., Mandrup-Poulsen, Thomas, Pandey, K., Purcell, A. W. & Marzec, Michal Tomasz, 2022, In: Biomedicines. 10, 4, 814.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

    Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling

    Ghiasi, S. M., Dahlby, T., Hede Andersen, C., Haataja, L., Petersen, S., Omar-Hmeadi, M., Yang, M., Pihl, Celina, Bresson, S. E., Khilji, Muhammad Saad, Klindt, K., Cheta, O., Perone, M. J., Tyrberg, B., Prats, C., Barg, S., Tengholm, A., Arvan, P., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, Apr 2019, In: Diabetes. 68, 4, p. 747-760 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in beta-Cells

    Dahlby, T., Simon, C., Backe, M. B., Dahllof, M. S., Holson, E., Wagner, B. K., Boni-Schnetzler, M., Marzec, Michal Tomasz, Lundh, M. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences. 21, 21, 18 p., 8016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

    Kasprzycka, M., Majewski, M., Wang, Z., Ptasznik, A., Wysocka, M., Zhang, Q., Marzec, Michal Tomasz, Gimotty, P., Crompton, M. R. & Wasik, M. A., 2006, In: American Journal of Pathology. 168, 5, p. 1631-1641 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Expression of FOXP3(+) regulatory T-cell phenotype in neoplastic and reactive cells in early mycosis fungoides

    Witkiewicz, A. K., Potoczek, M., Kasprzycka, M., Marzec, Michal Tomasz & Wasik, M., Jan 2008, In: Modern Pathology. 21, p. 103A-103A

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    FK506-Binding Protein 2 Participates in Proinsulin Folding

    Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, Borowiak, M., Wierer, M., MacDonald, P. E., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, 2023, In: Biomolecules. 13, 1, 20 p., 152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum

    Marzec, Michal Tomasz, Eletto, D. & Argon, Y., Mar 2012, In: B B A - Reviews on Cancer. 1823, 3, p. 774-87 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production

    Argon, Y., Bresson, S. E., Marzec, Michal Tomasz & Grimberg, A., 2020, In: Cells. 9, 8, 12 p., 1844.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Glutathione S-Transferase P1 Genetic Variant’s Influence on the HbA1c Level in Type Two Diabetic Patients

    Orlewska, K., Klusek, J., Głuszek, S., Klusek, J., Witczak, B., Wawszczak, M., Madej, Ł., Marzec, Michal Tomasz & Orlewska, E., 2023, In: International Journal of Environmental Research and Public Health. 20, 2, 9 p., 1520.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    IDF2022-0254 Glutathione S-transferase P1 genetic variants influence the HbA1c level in diabetic patients

    Klusek, J., Głuszek, S., Orlewska, K., Marzec, Michal Tomasz, Wawszczak-kasza, M., Madej, Ł., Klusek, J., Witczak, B. & Orlewska, E., 2023, In: Diabetes Research and Clinical Practice. 197, Suppl. 1, 1 p., 110268.

    Research output: Contribution to journalConference articleResearchpeer-review

  19. Published

    IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

    Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Immunometabolism in type 2 diabetes mellitus: tissue-specific interactions

    Pinheiro-Machado, E., Convey, E. G. & Marzec, Michal Tomasz, 2023, In: Archives of Medical Science. 19, 4, 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

    Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Jak3 contributes to the activation of ALK and Stat3 in ALK + anaplastic large cell lymphoma. Response.

    Wasik, M. A. & Marzec, Michal Tomasz, 2006, In: Laboratory Investigation. 86, 4, p. 420-421 2 p.

    Research output: Contribution to journalLetterResearch

  23. Published

    MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity

    Tyka, K., Joerns, A., Dunst, A., Tang, Y., Holgersen Bryde, Tenna, Mehmeti, I., Walentinsson, A., Marselli, L., Cnop, M., Tyrberg, B., Marzec, Michal Tomasz & Gurgul-Convey, E., 2021, In: B B A - Molecular Basis of Disease. 1867, 10, 12 p., 166199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    MCPIP1 regulates insulin biosynthesis and glucose-stimulated insulin secretion: [Meeting Abstract]

    Tyka, K., Brydde, T. H., Wilamowski, M., Jura, J., Marzec, Michal Tomasz & Gurgul-Convey, E., 2019, In: FEBS Open Bio. 9, S1, p. 87-87 P-01-064.

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming

    Marzec, Michal Tomasz, Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Woetmann, Anders , Zhang, Q., Turner, S. D., Ødum, Niels & Wasik, M. A., 15 Dec 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 12, p. 6200-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 129941679